Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models

Nature Cell Biology

Volumn 7, Issue 7, 2005, Pages 675-685

  Difilippantonio, Simone ^a   Celeste, Arkady ^a   Fernandez Capetillo, Oscar ^a,h   Chen, Hua Tang ^a   San Martin, Bernardo Reina ^b   Van Laethem, Francois ^a   Yang, Yong Ping ^c   Petukhova, Galina V ^d   Eckhaus, Michael ^e   Feigenbaum, Lionel ^f   Manova, Katia ^g   Kruhlak, Michael ^a   Camerini Otero, R Daniel ^d   Sharan, Shyam ^c   Nussenzweig, Michel ^b   Nussenzweig, André ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f SAIC FREDERICK INC   (United States)

^g MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^h Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; ATR PROTEIN; DNA; GENE PRODUCT; ISOPROTEIN; MRE11 PROTEIN; MUTANT PROTEIN; NIBRIN; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA TELANGIECTASIA; B CELL LYMPHOMA; B LYMPHOCYTE; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL MATURATION; CELL VIABILITY; CHROMOSOME FRAGILITY; CLINICAL FEATURE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; ENZYME ACTIVATION; ENZYME INACTIVATION; GENE EXPRESSION; GENE REARRANGEMENT; GONAD DYSFUNCTION; IMMUNE DEFICIENCY; IONIZING RADIATION; KNOCKOUT MOUSE; LETHALITY; MEIOSIS; METAPHASE; MOUSE; NIJMEGEN BREAKAGE SYNDROME; NONHUMAN; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STRESS; T LYMPHOCYTE; ULTRAVIOLET RADIATION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; B-LYMPHOCYTES; BINDING SITES; CELL CYCLE; CELL CYCLE PROTEINS; CHROMOSOME ABERRATIONS; CHROMOSOME BREAKAGE; CHROMOSOME DISORDERS; DISEASE MODELS, ANIMAL; DNA DAMAGE; DNA REPAIR ENZYMES; DNA REPLICATION; DNA-BINDING PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GONADS; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; LYMPHOMA, NON-HODGKIN; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTATION; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SYNDROME; T-LYMPHOCYTES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; ATAXIA TELANGIECTASIA;

EID: 22144462810     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1270     Document Type: Article

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