V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors

Genes and Development

Volumn 10, Issue 16, 1996, Pages 2038-2054

  Guidos, Cynthia J ^a,b   Williams, Christine J ^a,b   Grandal, Ildiko ^a   Knowles, Gisele ^a   Huang, Manley T F ^c,d   Danska, Jayne S ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c GenPharm International   (United States)

^d ALZA CORPORATION   (United States)

Author keywords

DNA repair; p53 protein; protein kinase; scid; V(D)J recombination

Indexed keywords

DNA DIRECTED DNA POLYMERASE; PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; DNA DAMAGE; DNA STRAND BREAKAGE; GENE REARRANGEMENT; GENETIC RECOMBINATION; GENOTOXICITY; IMMUNE DEFICIENCY; LYMPHOCYTE CULTURE; NONHUMAN; PRIORITY JOURNAL; PROLYMPHOCYTE; STEM CELL; TUMOR SUPPRESSOR GENE;

ANIMALIA;

EID: 0029858143     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.16.2038     Document Type: Article

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