Elevated Cu/Zn-SOD exacerbates radiation sensitivity and hematopoietic abnormalities of Atm-deficient mice

EMBO Journal

Volumn 20, Issue 7, 2001, Pages 1538-1546

  Peter, Yakov ^a   Rotman, Galit ^b   Lotem, Joseph ^a   Elson, Ari ^a   Shiloh, Yosef ^b   Groner, Yoram ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Ataxia telangiectasia; Atm knockout; Oxidative stress; Radiosensitivity; Transgenic SOD1

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA TELANGIECTASIA; BLOOD DISEASE; CANCER SUSCEPTIBILITY; CLINICAL FEATURE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE OVEREXPRESSION; HEMATOPOIESIS; IMMUNE DEFICIENCY; IONIZING RADIATION; KNOCKOUT MOUSE; MALE; MOUSE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; TRANSGENE;

ANIMALS; ATAXIA TELANGIECTASIA; CELL CYCLE PROTEINS; CEREBELLUM; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; FEMALE; GROWTH DISORDERS; HEMATOPOIESIS; HUMANS; KIDNEY; LIVER; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN-SERINE-THREONINE KINASES; RADIATION TOLERANCE; SPLEEN; SUPEROXIDE DISMUTASE; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; ATAXIA; ATAXIA TELANGIECTASIA; MURINAE;

EID: 0035794540     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.7.1538     Document Type: Article

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