The chemotherapy of Chagas' disease: An overview

Mini-Reviews in Medicinal Chemistry

Volumn 5, Issue 5, 2005, Pages 499-519

  Paulino, Margot ^a   Iribarne, F ^a   Dubin, M ^b   Aguilera Morales, S ^c   Tapia, O ^d   Stoppani, A O M ^b  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c UNIVERSIDAD CATÓLICA DEL NORTE   (Chile)

^d UPPSALA UNIVERSITY   (Sweden)

Author keywords

Antichagasic agents; Chemotherapy targets; Trypanosomiasis; Trypanothione metabolism; Trypanothione reductase inhibitors

Indexed keywords

2 (2,4 DIFLUOROPHENYL) 1 [3 [2 [4 (2,2,3,3 TETRAFLUOROPROPOXY)PHENYL]VINYL] 1,2,4 TRIAZOL 1 YL] 3 (1,2,4 TRIAZOL 1 YL) 2 PROPANOL; ADENOSINE DERIVATIVE; ALBACONAZOLE; ALLOPURINOL; ANTIFUNGAL AGENT; ANTIPROTOZOAL AGENT; BENZIMIDAZOLE; CRUZIPAIN; DIHYDROFOLATE REDUCTASE; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; FLAVONOID; FLUCONAZOLE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; ITRACONAZOLE; KETOCONAZOLE; METHOTREXATE; NAPHTHOQUINONE; NIFURTIMOX; NITROFURAN; PAMIDRONIC ACID; PHENOTHIAZINE DERIVATIVE; POSACONAZOLE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; STEROL; TRYPANOTHIONE REDUCTASE; UNINDEXED DRUG;

ANTIBIOTIC RESISTANCE; ANTIPROTOZOAL ACTIVITY; CHAGAS DISEASE; DISEASE MODEL; DRUG DESIGN; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; IN VIVO STUDY; NONHUMAN; OXIDATIVE STRESS; PARASITEMIA; REVIEW; STEROL SYNTHESIS; TRYPANOSOMA CRUZI;

ANIMALS; CHAGAS DISEASE; HUMANS; NADH, NADPH OXIDOREDUCTASES; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI; TRYPANOSOMATINA;

EID: 18044365378     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389557053765565     Document Type: Review

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