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Journal of Molecular Structure: THEOCHEM

Volumn 584, Issue 1-3, 2002, Pages 95-105

Computer assisted design of potentially active anti-trypanosomal compounds

(14) Paulino, Margot a Iribarne, Federico a Hansz, María a Vega, Mauricio a Seoane, Gustavo a Cerecetto, Hugo a Di Maio, Rossanna a Caracelli, Ignez b Zukerman Schpector, Julio b Olea, Claudio c Stoppani, Andrés O M d Berriman, Mathew e Fairlamb, Alan H e Tapia, Orlando f

a UNIVERSIDAD DE LA REPÚBLICA (Uruguay)

b FEDERAL UNIVERSITY OF SÃO CARLOS (Brazil)

c UNIVERSITY OF CHILE (Chile)

d UNIVERSIDAD DE BUENOS AIRES (Argentina)

e UNIVERSITY OF DUNDEE (United Kingdom)

f UPPSALA UNIVERSITY (Sweden)

Author keywords

Anti trypanosomal compounds; Drug design; Inhibition assays; Molecular modeling; Trypanosomiasis

Indexed keywords

2 METHOXYPHENYL 1 (5 NITROFURFURILIDENE) SEMICARBAZIDE; 4 (2 METHOXYETHYL) 1 (5 NITROFURFURILIDENE) SEMICARBAZIDE; 4 BUTYL (5 NITROFURFURILIDENE) SEMICARBAZIDE; 4 HEXYL 1 (5 NITROFURFURILIDENE) SEMICARBAZIDE; 5 NITROTHIOPHENE DERIVATIVE; ANTITRYPANOSOMAL AGENT; DISULFIDE; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONYLSPERMIDINE DISULFIDE; N1 [(5 NITRO 2 FURYL)METHYLIDENE] N4 [4 [3 (2,2,2 TRIFLUOROACETYL)HEXAHYDRO 1 1 PYRIMIDINYLL]BUTYL] SEMICARBAZIDE; TRYPANOTHIONE; TRYPANOTHIONE REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; COMPUTER; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; GROWTH INHIBITION; MOLECULAR MODEL; NONHUMAN; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS;

EID: 0037177688 PISSN: 01661280 EISSN: None Source Type: Journal
DOI: 10.1016/S0166-1280(02)00009-X Document Type: Article

Times cited : (22)

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