Down-regulation of Leishmania donovani trypanothione reductase by heterologous expression of a trans-dominant mutant homologue: Effect on parasite intracellular survival

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 9, 1998, Pages 5311-5316

  Tovar, Jorge ^a   Cunningham, Mark L ^a,b   Smith, Aden C ^a   Croft, Simon L ^a   Fairlamb, Alan H ^a,c  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

FLAVOPROTEIN; MUTANT PROTEIN; OXIDOREDUCTASE; TRYPANOTHIONE REDUCTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL GROWTH; DOWN REGULATION; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; GENE EXPRESSION; LEISHMANIA DONOVANI; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMASTIGOTE; TRANSGENE;

ANIMALS; DIMERIZATION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, DOMINANT; HETEROZYGOTE; HYDROGEN PEROXIDE; LEISHMANIA DONOVANI; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED BALB C; NADH, NADPH OXIDOREDUCTASES; OXIDATION-REDUCTION;

ANIMALIA; LEISHMANIA DONOVANI; MURINAE; TRYPANOSOMA; TRYPANOSOMA CRUZI; TRYPANOSOMATIDAE;

EID: 0032574808     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.9.5311     Document Type: Article

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