Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 19, 1996, Pages 10383-10387

  Mukhopadhyay, Rita ^a   Dey, Saibal ^a   Xu, Naxing ^b   Gage, Douglas ^b   Lightbody, James ^a   Ouellette, Marc ^c   Rosen, Barry P ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Michigan State University   (United States)

^c LAVAL UNIVERSITY   (Canada)

Author keywords

arsenite; drug resistance; Pentostam; transport ATPase; trypanothione

Indexed keywords

ANTIMONY DERIVATIVE; CYSTEINE; GLUTATHIONE; ORGANOARSENIC DERIVATIVE; STIBOGLUCONATE SODIUM; THIOL GROUP; TRYPANOTHIONE;

ARTICLE; CONTROLLED STUDY; DRUG RESISTANCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEISHMANIA; LEISHMANIASIS; MASS SPECTROMETRY; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROMASTIGOTE;

ANIMALS; ANTIMONY SODIUM GLUCONATE; ANTIPROTOZOAL AGENTS; ARSENIC POISONING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; DRUG RESISTANCE; GLUTATHIONE; LEISHMANIA; MODELS, BIOLOGICAL; MUTATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPERMIDINE;

LEISHMANIA TARENTOLAE;

EID: 0029841913     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.19.10383     Document Type: Article

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