Altered expression of cruzipain and a cathepsin B-like target in a Trypanosoma cruzi cell line displaying resistance to synthetic inhibitors of cysteine-proteinases

Molecular and Biochemical Parasitology

Volumn 109, Issue 1, 2000, Pages 47-59

  Yong, Vladimir ^a   Schmitz, Verônica ^a   Vannier Santos, Marcos André ^a   De A Lima, Ana Paula C ^a   Lalmanach, Gilles ^b   Juliano, Luiz ^c   Gauthier, Francis ^b   Scharfstein, Julio ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITÉ DE TOURS   (France)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Chagas' disease; Cruzipain; Cysteine proteinase; Drug resistance; Trypanosoma cruzi

Indexed keywords

BENZNIDAZOLE; CATHEPSIN B; CRUZIPAIN; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; N BENZYLCARBONYL(S BENZYL)CYSTEINYLPHENYLALANYLDIAZOMETHYLKETONE; NIFURTIMOX; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CHAGAS DISEASE; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA CRUZI;

ANIMALS; ANTIGENS, PROTOZOAN; CATHEPSIN B; CELL LINE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DRUG RESISTANCE, MICROBIAL; FLOW CYTOMETRY; GLYCOPROTEINS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; NIFURTIMOX; NITROIMIDAZOLES; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 0033898794     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(00)00237-1     Document Type: Article

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