New spermine and spermidine derivatives as potent inhibitors of trypanosoma cruzi trypanothione reductase

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 7, 1997, Pages 1249-1256

  Bonnet, Béatrice ^a   Soullez, David ^a   Davioud Charvet, Elisabeth ^a   Landry, Valérie ^a   Horvath, Dragos ^a   Sergheraert, Christian ^a  

^a INSTITUT PASTEUR DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CLOMIPRAMINE; OXIDOREDUCTASE; SPERMIDINE DERIVATIVE; SPERMINE DERIVATIVE;

ALGORITHM; ARTICLE; COMPUTER SIMULATION; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA CRUZI;

ANIMALS; ENZYME INHIBITORS; NADH, NADPH OXIDOREDUCTASES; PROTOZOAN PROTEINS; SPERMIDINE; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA CRUZI;

TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0030838722     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00070-9     Document Type: Article

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