Co-amplification of the γ-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae

EMBO Journal

Volumn 16, Issue 11, 1997, Pages 3057-3065

  Grondin, Katherine ^b   Haimeur, Anass ^b   Mukhopadhyay, Rita ^a   Rosen, Barry P ^a   Ouellette, Marc ^b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

ABC transporter; Drug resistance; Glutathione; Leishmania; Trypanothione

Indexed keywords

ABC TRANSPORTER; ARSENIC TRIOXIDE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; TRYPANOTHIONE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; GENE AMPLIFICATION; GLUTATHIONE METABOLISM; LEISHMANIA; MUTANT; NONHUMAN; PRIORITY JOURNAL; REVERTANT;

AMINO ACID SEQUENCE; ANIMALS; ARSENITES; ATP-BINDING CASSETTE TRANSPORTERS; DRUG RESISTANCE; GENE AMPLIFICATION; GENES, PROTOZOAN; GENETIC VECTORS; GLUTAMATE-CYSTEINE LIGASE; LEISHMANIA; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PROTOZOAN PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SULFHYDRYL COMPOUNDS; TRANSFECTION;

EID: 0030924243     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.11.3057     Document Type: Article

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