New approaches to Leishmania chemotherapy: Pteridine Reductase 1 (PTR1) as a target and modulator of antifolate sensitivity

Parasitology

Volumn 114, Issue SUPPL. 1, 1997, Pages

  Nare, B ^a   Luba, J ^b   Hardy, L W ^b   Beverley, S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Chemotherapy; Drug resistance; Leishmania; Methotrexate; Pteridine reductase

Indexed keywords

ANTIPARASITIC AGENT; FOLIC ACID ANTAGONIST; PTERIDINE;

CONFERENCE PAPER; DRUG MECHANISM; DRUG TRANSPORT; ENZYME ACTIVITY; FOLATE METABOLISM; LEISHMANIA; LEISHMANIASIS; NONHUMAN; PRIORITY JOURNAL; TREATMENT OUTCOME;

ANIMALS; DRUG RESISTANCE; FOLIC ACID ANTAGONISTS; LEISHMANIA; LEISHMANIASIS; METHOTREXATE; OXIDOREDUCTASES; PTERIDINES;

ANIMALIA; EUKARYOTA; PROTOZOA; TRYPANOSOMATIDAE;

EID: 0030921824     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0031182097001133     Document Type: Article

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