Cytotoxicity of β-lapachone, an o-naphthoquinone with possible therapeutic use

Medicina

Volumn 61, Issue 3, 2001, Pages 343-350

  Dubin, M ^a   Fernandez Villamil, S H ^a   Stoppani, A O M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

lapachone; Apoptosis; Cancer; Cytostatic agents; PARP; Topoisomerases

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; BETA LAPACHONE; CALPAIN; CASPASE; DIHYDROLIPOAMIDE DEHYDROGENASE; DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEASE; OXYGEN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCING AGENT; STRESS ACTIVATED PROTEIN KINASE; THIOL PROTEINASE; ANTINEOPLASTIC ANTIBIOTIC; BETA-LAPACHONE; NAPHTHOQUINONE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER INHIBITION; CATALYSIS; CELL DEATH; CLINICAL OBSERVATION; COLON CANCER; CONTROLLED STUDY; DNA STRUCTURE; DNA SYNTHESIS INHIBITION; DRUG CYTOTOXICITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; ISOLATION PROCEDURE; LARYNX CANCER; LEUKEMIA CELL; NONHUMAN; OVARY CANCER; OXIDATION REDUCTION REACTION; PROSTATE CANCER; SQUAMOUS CELL CARCINOMA; TREE; TRYPANOSOMA CRUZI; TUMOR GROWTH; WALKER CARCINOMA; YOSHIDA SARCOMA; ANIMAL; CARCINOMA; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; METABOLISM; NEOPLASM; PHYSIOLOGY; REVIEW;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CARCINOMA 256, WALKER; DNA TOPOISOMERASES, TYPE I; HUMANS; NAPHTHOQUINONES; NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; SARCOMA, YOSHIDA;

EID: 0035223367     PISSN: 00257680     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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