-
1
-
-
0021401673
-
Free radical metabolism in the mode of action of chemotherapeutic agents and phagocytic cells on Trypanosoma cruzi
-
Docampo R., Moreno S.N.J. Free radical metabolism in the mode of action of chemotherapeutic agents and phagocytic cells on Trypanosoma cruzi. Rev. Infect. Dis. 6:1984;223-238.
-
(1984)
Rev. Infect. Dis.
, vol.6
, pp. 223-238
-
-
Docampo, R.1
Moreno, S.N.J.2
-
2
-
-
0025166484
-
Sensitivity of parasites to free radical damage by antiparasitic drugs
-
Docampo R. Sensitivity of parasites to free radical damage by antiparasitic drugs. Chem. Biol. Interactions. 73:1990;1-27.
-
(1990)
Chem. Biol. Interactions
, vol.73
, pp. 1-27
-
-
Docampo, R.1
-
3
-
-
0032582844
-
Overexpression of superoxide dismutase in Trypanosoma cruzi results in increased sensitivity to the trypanocidal agents gentian violet and benznidazole
-
Temperton N.J., Wilkinson S.R., Meyer D.J., Kelly J.M. Overexpression of superoxide dismutase in Trypanosoma cruzi results in increased sensitivity to the trypanocidal agents gentian violet and benznidazole. Mol. Biochem. Parasitol. 96:1998;167-176.
-
(1998)
Mol. Biochem. Parasitol.
, vol.96
, pp. 167-176
-
-
Temperton, N.J.1
Wilkinson, S.R.2
Meyer, D.J.3
Kelly, J.M.4
-
4
-
-
0030997726
-
Molecular cloning and characterization of two iron superoxide dismutase cDNAs from Trypanosoma cruzi
-
Ismail S.O., Paramchuk W., Sheiky Y.A., Reed S.G., Bhatia A., Gedamu L. Molecular cloning and characterization of two iron superoxide dismutase cDNAs from Trypanosoma cruzi. Mol. Biochem. Parasitol. 86:1997;187-197.
-
(1997)
Mol. Biochem. Parasitol.
, vol.86
, pp. 187-197
-
-
Ismail, S.O.1
Paramchuk, W.2
Sheiky, Y.A.3
Reed, S.G.4
Bhatia, A.5
Gedamu, L.6
-
5
-
-
0030458544
-
Antioxidant defense mechanisms in parasitic protozoa
-
Melhotra R.K. Antioxidant defense mechanisms in parasitic protozoa. Crit. Rev. Microbiol. 22:1996;295-314.
-
(1996)
Crit. Rev. Microbiol.
, vol.22
, pp. 295-314
-
-
Melhotra, R.K.1
-
6
-
-
0019325482
-
Deficient metabolic utilization of hydrogen peroxide in Trypanosoma cruzi
-
Boveris A., Sies H., Martino E.E., Docampo R., Turrens J.F., Stoppani A.O.M. Deficient metabolic utilization of hydrogen peroxide in Trypanosoma cruzi. Biochem. J. 188:1980;643-648.
-
(1980)
Biochem. J.
, vol.188
, pp. 643-648
-
-
Boveris, A.1
Sies, H.2
Martino, E.E.3
Docampo, R.4
Turrens, J.F.5
Stoppani, A.O.M.6
-
7
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance B., Sies H., Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59:1979;527-605.
-
(1979)
Physiol. Rev.
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
8
-
-
0000704119
-
The selenoprotein glutathione peroxidase
-
In: Dophin, D.; Poulson, R. and Avramocic, O., eds. New York: Part A. John Wiley & Sons Inc.
-
Flohé, L. The selenoprotein glutathione peroxidase. In: Dophin, D.; Poulson, R. and Avramocic, O., eds. Glutathione: chemical, biochemical and medical aspects. New York: Part A. John Wiley & Sons Inc., 1989: 643-676.
-
(1989)
Glutathione: Chemical, Biochemical and Medical Aspects
, pp. 643-676
-
-
Flohé, L.1
-
9
-
-
0029187630
-
The diversity of glutathione peroxidases
-
Ursini F., Maiorino M., Brigelius-Flohé R., Aumann K.D., Roveri A., Schomburg D., Flohé L. The diversity of glutathione peroxidases. Meth. Enzymol. 252:1995;38-53.
-
(1995)
Meth. Enzymol.
, vol.252
, pp. 38-53
-
-
Ursini, F.1
Maiorino, M.2
Brigelius-Flohé, R.3
Aumann, K.D.4
Roveri, A.5
Schomburg, D.6
Flohé, L.7
-
10
-
-
0021933665
-
Identification of a novel, thiol-containing co-factor essential for glutathione reductase enzyme activity in trypanosomatids
-
Fairlamb A.H., Cerami A. Identification of a novel, thiol-containing co-factor essential for glutathione reductase enzyme activity in trypanosomatids. Mol. Biochem. Parasitol. 14:1985;187-198.
-
(1985)
Mol. Biochem. Parasitol.
, vol.14
, pp. 187-198
-
-
Fairlamb, A.H.1
Cerami, A.2
-
11
-
-
0027375651
-
Trypanothione-dependent peroxide metabolism in Trypanosoma cruzi different stages
-
Carnieri E.G.S., Moreno S.N.J., Docampo R. Trypanothione-dependent peroxide metabolism in Trypanosoma cruzi different stages. Mol. Biochem. Parasitol. 61:1993;79-86.
-
(1993)
Mol. Biochem. Parasitol.
, vol.61
, pp. 79-86
-
-
Carnieri, E.G.S.1
Moreno, S.N.J.2
Docampo, R.3
-
12
-
-
0030861413
-
A unique cascade of oxidoreductases catalyses trypanothione-mediated peroxide metabolism in Crithidia fasciculata
-
Nogoceke E., Gommel D.U., Kiess M., Kalisz H.M., Flohé L. A unique cascade of oxidoreductases catalyses trypanothione-mediated peroxide metabolism in Crithidia fasciculata. Biol. Chem. 378:1997;827-836.
-
(1997)
Biol. Chem.
, vol.378
, pp. 827-836
-
-
Nogoceke, E.1
Gommel, D.U.2
Kiess, M.3
Kalisz, H.M.4
Flohé, L.5
-
13
-
-
0026793462
-
Metabolism and functions of trypanothione in the kinetoplastida
-
Fairlamb A.H., Cerami A. Metabolism and functions of trypanothione in the kinetoplastida. Ann. Rev. Biochem. 46:1992;695-729.
-
(1992)
Ann. Rev. Biochem.
, vol.46
, pp. 695-729
-
-
Fairlamb, A.H.1
Cerami, A.2
-
14
-
-
0000876731
-
Lipoamide dehydrogenase, glutathione reductase, thioredoxin reductase and mercuric ion reductase - A family of flavoenzyme transhydrogenases
-
In: Müller, F., ed. Boca Raton, FL: CRC Press
-
Williams, C. H., Jr. Lipoamide dehydrogenase, glutathione reductase, thioredoxin reductase and mercuric ion reductase - a family of flavoenzyme transhydrogenases. In: Müller, F., ed. Chemistry and biochemistry of flavoenzymes. Boca Raton, FL: CRC Press, 1992: Vol. III:121-211.
-
(1992)
Chemistry and Biochemistry of Flavoenzymes
, vol.3
, pp. 121-211
-
-
Williams C.H., Jr.1
-
15
-
-
0023150396
-
Trypanothione reductase from Trypanosoma cruzi. Purification and characterization of the crystalline enzyme
-
Kraut-Siegel R.L., Enders B., Henderson G.B., Fairlamb A.H., Schirmer R.H. Trypanothione reductase from Trypanosoma cruzi. Purification and characterization of the crystalline enzyme. Eur. J. Biochem. 164:1987;123-128.
-
(1987)
Eur. J. Biochem.
, vol.164
, pp. 123-128
-
-
Kraut-Siegel, R.L.1
Enders, B.2
Henderson, G.B.3
Fairlamb, A.H.4
Schirmer, R.H.5
-
16
-
-
0031719808
-
Sequence, heterologous expression and functional characterization of a novel tryparedoxin from Crithidia fasciculata
-
Montemartini M., Kalisz H.M., Kiess M., Nogoceke E., Singh M., Steinert P., Flohé L. Sequence, heterologous expression and functional characterization of a novel tryparedoxin from Crithidia fasciculata. Biol. Chem. 379:1998;1137-1142.
-
(1998)
Biol. Chem.
, vol.379
, pp. 1137-1142
-
-
Montemartini, M.1
Kalisz, H.M.2
Kiess, M.3
Nogoceke, E.4
Singh, M.5
Steinert, P.6
Flohé, L.7
-
17
-
-
0000246509
-
Sequence, heterologous expression and functional characterization of Tryparedoxin 1 from Crithidia fasciculata
-
Guerrero S.A., Flohé L., Kalisz H.M., Montemartini M., Nogoceke E., Hecht H.J., Steinert P., Singh M. Sequence, heterologous expression and functional characterization of Tryparedoxin 1 from Crithidia fasciculata. Eur. J. Biochem. 259:1998;789-794.
-
(1998)
Eur. J. Biochem.
, vol.259
, pp. 789-794
-
-
Guerrero, S.A.1
Flohé, L.2
Kalisz, H.M.3
Montemartini, M.4
Nogoceke, E.5
Hecht, H.J.6
Steinert, P.7
Singh, M.8
-
18
-
-
0030880228
-
Catalytic characteristics of tryparedoxin
-
Gommel D.U., Nogoceke E., Morr M., Kiess M., Kalisz H.M., Flohé L. Catalytic characteristics of tryparedoxin. Eur. J. Biochem. 248:1997;913-918.
-
(1997)
Eur. J. Biochem.
, vol.248
, pp. 913-918
-
-
Gommel, D.U.1
Nogoceke, E.2
Morr, M.3
Kiess, M.4
Kalisz, H.M.5
Flohé, L.6
-
19
-
-
0033200161
-
Activation of active site cysteine residues in the peroxiredoxin-type tryparedoxin peroxidase of Crithidia fasciculata
-
Montemartini M., Kalisz H.M., Steinert P., Flohé L. Activation of active site cysteine residues in the peroxiredoxin-type tryparedoxin peroxidase of Crithidia fasciculata. Eur. J. Biochem. 264:1999;516-524.
-
(1999)
Eur. J. Biochem.
, vol.264
, pp. 516-524
-
-
Montemartini, M.1
Kalisz, H.M.2
Steinert, P.3
Flohé, L.4
-
20
-
-
0000582767
-
Sobre uma cepa de Trypanosoma cruzi altamente virulenta para camundongo branco
-
Silva H.P., Nussenzweig V. Sobre uma cepa de Trypanosoma cruzi altamente virulenta para camundongo branco. Folia Clin. Biol. 20:1953;191-207.
-
(1953)
Folia Clin. Biol.
, vol.20
, pp. 191-207
-
-
Silva, H.P.1
Nussenzweig, V.2
-
21
-
-
78651145402
-
Growth and differentiation of Trypanosoma cruzi. Origin of metacyclic trypanosomes in liquid media
-
Camargo E.P. Growth and differentiation of Trypanosoma cruzi. Origin of metacyclic trypanosomes in liquid media. Rev. Inst. Med. Trop. 6:1964;93-100.
-
(1964)
Rev. Inst. Med. Trop.
, vol.6
, pp. 93-100
-
-
Camargo, E.P.1
-
23
-
-
0032570772
-
Sequence analysis of the tryparedoxin peroxidase gene from Crithidia fasciculata and its functional expression in Escherichia coli
-
Montemartini M., Nogoceke E., Singh M., Steinert P., Flohé L., Kalisz H.M. Sequence analysis of the tryparedoxin peroxidase gene from Crithidia fasciculata and its functional expression in Escherichia coli. J. Biol. Chem. 273:1998;4864-4871.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 4864-4871
-
-
Montemartini, M.1
Nogoceke, E.2
Singh, M.3
Steinert, P.4
Flohé, L.5
Kalisz, H.M.6
-
24
-
-
0033230579
-
Glutathione and trypanothione in parasitic hydroperoxide metabolism
-
Flohé L., Hecht H.-J., Steinert P. Glutathione and trypanothione in parasitic hydroperoxide metabolism. Free Radic. Biol. Med. 27:1999;966-984.
-
(1999)
Free Radic. Biol. Med.
, vol.27
, pp. 966-984
-
-
Flohé, L.1
Hecht, H.-J.2
Steinert, P.3
-
25
-
-
0038790585
-
T. brucei tryparedoxin, a thioredoxin-like protein in African trypanosomes
-
Lüdemann H., Dormeyer M., Sticherling C., Stallmann D., Follmann H., Kraut-Siegel R.L. T. brucei tryparedoxin, a thioredoxin-like protein in African trypanosomes. FEBS Letters. 431:1998;381-385.
-
(1998)
FEBS Letters
, vol.431
, pp. 381-385
-
-
Lüdemann, H.1
Dormeyer, M.2
Sticherling, C.3
Stallmann, D.4
Follmann, H.5
Kraut-Siegel, R.L.6
-
26
-
-
0032945243
-
Cytoplasmic localization of the trypanothione peroxidase system in Crithidia fasciculata
-
Steinert P., Dittmar K., Kalisz H.M., Montemartini M., Nogoceke E., Rohde M., Singh M., Flohé L. Cytoplasmic localization of the trypanothione peroxidase system in Crithidia fasciculata. Free Radic. Biol. Med. 26:1999;844-849.
-
(1999)
Free Radic. Biol. Med.
, vol.26
, pp. 844-849
-
-
Steinert, P.1
Dittmar, K.2
Kalisz, H.M.3
Montemartini, M.4
Nogoceke, E.5
Rohde, M.6
Singh, M.7
Flohé, L.8
-
27
-
-
0028587273
-
Trypanosoma cruzi: Immunolocalization of trypanothione reductase
-
Meziane-Cherif D., Aumercier M., Kora I., Sergheraert C., Tartar A., Dubremetz J.F., Ouaissi M.A. Trypanosoma cruzi immunolocalization of trypanothione reductase . Exp. Parasitol. 79:(4):1994;536-541.
-
(1994)
Exp. Parasitol.
, vol.79
, Issue.4
, pp. 536-541
-
-
Meziane-Cherif, D.1
Aumercier, M.2
Kora, I.3
Sergheraert, C.4
Tartar, A.5
Dubremetz, J.F.6
Ouaissi, M.A.7
-
28
-
-
0030994263
-
Convenient isolation and kinetic mechanism of glutathionylspermidine synthetase from Crithidia fasciculata
-
Koenig K., Menge U., Kiess M., Wray V., Flohé L. Convenient isolation and kinetic mechanism of glutathionylspermidine synthetase from Crithidia fasciculata. J. Biol. Chem. 272:1997;11908-11915.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11908-11915
-
-
Koenig, K.1
Menge, U.2
Kiess, M.3
Wray, V.4
Flohé, L.5
-
29
-
-
0032584748
-
Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata
-
Tetaud E., Manai F., Barrett M.P., Nadeau K., Walsh C.T., Fairlamb A.H. Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata. J. Biol. Chem. 273:1998;19383-19390.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19383-19390
-
-
Tetaud, E.1
Manai, F.2
Barrett, M.P.3
Nadeau, K.4
Walsh, C.T.5
Fairlamb, A.H.6
-
30
-
-
0343987888
-
Verification of trypanothione reductase as a drug target using inducible gene expression
-
Zentrum für Molekularbiologie (ZMBH), Heidelberg, Germany
-
Krieger, S.; Schwarz, W.; Kraut-Siegel, L.; Clayton, C. Verification of trypanothione reductase as a drug target using inducible gene expression. "Expert Meeting on Enzymes of the Parasitic Thiol Metabolism as Drug Targets". Zentrum für Molekularbiologie (ZMBH), Heidelberg, Germany (1998).
-
(1998)
Expert Meeting on Enzymes of the Parasitic Thiol Metabolism As Drug Targets
-
-
Krieger, S.1
Schwarz, W.2
Kraut-Siegel, L.3
Clayton, C.4
|