Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis

FASEB Journal

Volumn 14, Issue 5, 2000, Pages 729-739

  Daugas, Eric ^a   Susin, Santos A ^a   Zamzami, Naoufal ^a   Ferri, Karine F ^a   Irinopoulou, Theano ^e   Larochette, Nathanael ^a   Prévost, Marie Christine ^b   Leber, Brian ^c   Andrews, David ^d   Penninger, Josef ^f   Kroemer, Guido ^a,g  

^a CNRS   (France)

^b INSTITUT PASTEUR   (France)

^c MCMASTER UNIVERSITY MEDICAL CENTRE   (Canada)

^d MCMASTER UNIVERSITY   (Canada)

^e HÔPITAL BROUSSAIS   (France)

^f UNIVERSITY OF TORONTO   (Canada)

^g NONE   (France)

Author keywords

Antioncogene; Mitochondrial transmembrane potential; Oncogene; Permeability transition; Programmed cell death

Indexed keywords

APOPTOSIS INDUCING FACTOR; CERAMIDE; ETOPOSIDE; M PROTEIN; MYC PROTEIN; PROTEIN BCL 2; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL NUCLEUS MEMBRANE; CHROMATIN CONDENSATION; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0034117177     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.14.5.729     Document Type: Article

References (42)

1. Zamzami, N., Susin, S. A., Marchetti, P., Hirsch, T., G-mez-Monterrey, I., Castedo, M., and Kroemer, G. (1996) Mitochondrial control of nuclear apoptosis. J. Exp. Med. 183, 1533-1544
2. Liu, X. S., Kim, C. N., Yang, J., Jemmerson, R., and Wang, X. (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome C. Cell 86, 147-157
3. Susin, S. A., Zamzami, N., Castedo, M., Hirsch, T., Marchetti, P., Macho, A., Daugas, E., Geuskens, M., and Kroemer, G. (1996) Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J. Exp. Med. 184, 1331-1342
4. vander Heiden, M. G., Chandal, N. S., Williamson, E. K., Schumacker, P. T., and Thompson, C. B. (1997) Bcl-XL regulates the membrane potential and volume homeostasis of mitochondria. Cell 91, 627-637
5. Petit, P. X., Goubern, M., Diolez, P., Susin, S. A., Zamzami, N., and Kroemer, G. (1998) Disruption of the outer mitochondrial membrane as a result of mitochondrial swelling. The impact of irreversible permeability transition. FEBS Lett. 426, 111-116
6. Kluck, R. M., Bossy-Wetzel, E., Green, D. R., and Newmeyer, D. D. (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275, 1132-1136
7. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T.-I., Jones, D. P., and Wang, X. (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275, 1129-1132
8. Jürgensmeier, J. M., Xie, Z., Deveraux, Q., Ellerby, L., Bredesen, D., and Reed, J. C. (1998) Bax directly induces release of cytochrome c from isolated mitochondria. Prof. Natl. Acad. Sci. USA 95, 4997-5002
9. Desagher, S., Osen-Sand, A., Nichols, A., Eskes, R., Montessuit, S., Lauper, S., Maundrell, K., Antonsson, B., and Martinou, J.-C. (1999) Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. J. Cell Biol. 144, 891-901
10. Shimizu, S., Narita, M., and Tsujimoto, Y. (1999) Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature (London) 399, 483-487
11. Marzo, I., Brenner, C., Zamzami, N., Susin, S. A., Beutner, G., Brdiczka, D., Rémy, R., Xie, Z.-H., Reed, J. C., and Kroemer, G. (1998) The permeability transition pore complex: a target for apoptosis regulation by caspases and Bcl-2 related proteins. J. Exp. Med. 187, 1261-1271
12. Marzo, I., Brenner, C., Zamzami, N., Jürgensmeier, J., Susin, S. A., Vieira, H. L. A., Prévost, M.-C., Xie, Z., Mutsiyama, S., Reed, J. C., and Kroemer, G. (1998) Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281, 2027-2031
13. Gross, A., Jockel, J., Wei, M. C., and Korsmeyer, S. J. (1998) Enforced dimerization of Bax results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 17, 3878-3885
14. Narita, M., Shimizu, S., Ito, T., Chittenden, T., Lutz, R. J., Matsuda, H., and Tsujimoto, Y. (1998) Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc. Natl. Acad. Sci. USA 95, 14681-14686
15. Zhou, H., Henzel, W. J., Liu, X., Lutschg, A., and Wang, X. D. (1997) Apaf-1, a human protein homologous to C. elegans Ced-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-405-413
16. Xiang, J., Chao, D. T., and Korsmeyer, S. J. (1996) Bax-induced cell death may not require interleukin 1β-converting enzyme-like proteases. Proc. Natl. Acad. Sci. USA 93, 14559-14563
17. McCarthy, N. J., Whyte, M. K. B., Gilbert, C. S., and Evan, G. I. (1997) Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J. Cell Biol. 136, 215-227
18. Hirsch, T., Marchetti, P., Susin, S. A., Dallaporta, B., Zamzami, N., Marzo, I., Geuskens, M., and Kroemer, G. (1997) The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene 15, 1573-1582
19. Deas, O., Dumont, C., MacFarlane, M., Rouleau, M., Hebib, C., Harper, F., Hirsch, F., Charpentier, B., Cohen, G. M., and Senik, A. (1998) Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes. J. Immunol. 161, 3375-3383
20. Green, D. R., and Kroemer, G. (1998) The central execution of apoptosis: mitochondria or caspases? Trends Cell Biol. 8, 267-271
21. Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Snow, B. E., Brothers, G. M., Mangion, J., Jacotot, E., Costantini, P., Loeffler, M., Larochette, N., Goodlett, D. R., Aebersold, R., Siderovski, D. P., Penninger, J. M., and Kroemer, G. (1999) Molecular characterization of mitochondrial apoptosis-inducing factor (AIF). Nature (London) 397, 441-446
22. Shimizu, S., Eguchi, Y., Kamiike, W., Waguri, S., Uchiyama, Y., Matsuda, H., and Tsujimoto, Y. (1996) Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions. Oncogene 12, 2045-2050
23. Nieminen, A. L., Saylor, A. K., Tesfai, S. A., Herman, B., and Lemasters, J. J. (1995) Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide. Biochem. J. 307, 99-106
24. Saikumar, P., Dong, Z., Patel, Y., Hall, K., Hopfer, U., Weinberg, J. M., and Venkatachalam, M. A. (1998) Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury. Oncogene 17, 3401-3415
25. Kroemer, G., Dallaporta, B., and Resche-Rigon, M. (1998) The mitochondrial death/life regulator in apoptosis and necrosis. Annu. Rev. Physiol. 60, 619-642
26. Eguchi, Y., Shimizu, S., and Tsujimoto, Y. (1997) Intracellular ATP levels determine cell fate by apoptosis or necrosis. Cancer Res. 57, 1835-1840
27. Leist, M., Single, B., Castoldi, A. F., Kühnle, S., and Nicotera, P. (1997) Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med. 185, 1481-1486
28. Zhu, W., Cowie, A., Wasfy, G. W., Penn, L. Z., Leber, B., and Andrews, D. W. (1996) Bcl-2 mutants with restricted subcellular localization reveal spatially distinct pathways for apoptosis in different cell types. EMBO J. 15, 4130-4141
29. Evan, G. I., Wyllie, A. H., Gilbert, C. S., Littlewood, T. D., Land, H., Brooks, M., Waters, C. M., Penn, L. Z., and Hancock, D. C. (1992) Induction of apoptosis in fibroblasts by c-myc protein. Cell 69, 119-128
30. Macho, A., Decaudin, D., Castedo, M., Hirsch, T., Susin, S. A., Zamzami, N., and Kroemer, G. (1996) Chloromethyl-X-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. Cytometry 25, 333-340
31. Liou, W., Geuze, H. J., and Slot, J. W. (1996) Improving structural integrity of cryosections for immunogold labelling. Histochem. Cell Biol. 106, 41-58
32. Kawabe, Y., and Ochi, A. (1991) Programmed cell death and extrathymic reduction of Vβ8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature (London) 349, 245-248
33. Gonzalo, J. A., González-García, A., Martínez-A., C., and Kroemer, G. (1993) Glucocorticoid-mediated control of the clonal deletion and activation of peripheral T cells in vivo. J. Exp. Med. 177, 1239-1246
34. Brown, D. G., Sun, X. M., and Cohen, G. M. (1993) Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J. Biol. Chem. 268, 3037-3039
35. Bossy-Wetzel, E., Newmeyer, D. D., and Green, D. R. (1998) Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J. 17, 37-49
36. Eguchi, Y., Srinivasan, A., Tomaselli, K. J., Shimizu, S., and Tsujimoto, Y. (1999) ATP-dependent steps in apoptotic signal transduction. Cancer Res. 59, 2174-2181
37. Salamon, Z., and Tolling, G. (1997) Interaction of horse heart cytochrome c with lipid bilayer membranes: effects on redox potentials. J. Bioenerg. Biomembr. 29, 211-221
38. Jutila, A., Rytomaa, M., and Kinnunen, P. K. J. (1998) Detachment of cytochrome c by cationic drugs from membranes containing acidic phospholipids: comparison of lidocaine, propranolol, and gentamycin. Mol. Pharmacol. 54, 722-732
39. Liu, X., Zou, H., Slaughter, C., and Wang, X. (1997) DFF, a heterodimeric protein that functions downstream of caspase 3 to trigger DNA fragmentation during apoptosis. Cell 89, 175-184
40. Enari, M., Sakahira, H., Yokoyoma, H., Okawa, K., Iwamtsu, A., and Nagata, S. (1998) A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature (London) 391, 43-50
41. Sakahira, H., Enari, M., and Nagata, S. (1998) Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature (London) 391, 96-99
42. Liu, X. S., Li, P., Widlack, P., Zou, H., Luo, X., Garrard, W. T., and Wang, X. D. (1998) The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc. Natl. Acad. Sci. USA 95, 8461-8466