-
1
-
-
0026316096
-
Growth factors and cancer
-
Aaronson S.A. Growth factors and cancer Science 254 1991 1146 1153
-
(1991)
Science
, vol.254
, pp. 1146-1153
-
-
Aaronson, S.A.1
-
2
-
-
0024292722
-
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
-
Almoguera C. Shibata D. Forrester K. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes Cell 53 1988 549 554
-
(1988)
Cell
, vol.53
, pp. 549-554
-
-
Almoguera, C.1
Shibata, D.2
Forrester, K.3
-
3
-
-
0027525105
-
Identification of human activin and TGFß type I receptors that form heteromeric complexes with type II receptors
-
Attisano L. Caracamo J. Ventura F. Identification of human activin and TGFß type I receptors that form heteromeric complexes with type II receptors Cell 75 1993 671 680
-
(1993)
Cell
, vol.75
, pp. 671-680
-
-
Attisano, L.1
Caracamo, J.2
Ventura, F.3
-
4
-
-
0026527384
-
Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors
-
Attisano L. Wrana J.L. Cheifetz S. Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors Cell 68 1992 97 108
-
(1992)
Cell
, vol.68
, pp. 97-108
-
-
Attisano, L.1
Wrana, J.L.2
Cheifetz, S.3
-
5
-
-
0029810920
-
Attenuated ALK5 receptor expression in human pancreatic cancer: Correlation with resistance to growth inhibition
-
Baldwin R.L. Friess H. Yokoyama M. Attenuated ALK5 receptor expression in human pancreatic cancer: Correlation with resistance to growth inhibition Int J Cancer 67 1996 283 288
-
(1996)
Int J Cancer
, vol.67
, pp. 283-288
-
-
Baldwin, R.L.1
Friess, H.2
Yokoyama, M.3
-
6
-
-
0026334753
-
Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer
-
Barton C.M. Staddon S.L. Hughes C.M. Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer Br J Cancer 64 1991 1076 1082
-
(1991)
Br J Cancer
, vol.64
, pp. 1076-1082
-
-
Barton, C.M.1
Staddon, S.L.2
Hughes, C.M.3
-
7
-
-
0029890372
-
Increased expression of insulin receptor substrate-1 in human pancreatic cancer
-
Bergmann U. Funatomi H. Kornmann M. Increased expression of insulin receptor substrate-1 in human pancreatic cancer Biochem Biophys Res Commun 220 1996 886 890
-
(1996)
Biochem Biophys Res Commun
, vol.220
, pp. 886-890
-
-
Bergmann, U.1
Funatomi, H.2
Kornmann, M.3
-
8
-
-
0029788198
-
Insulin-like growth factor II activates mitogenic signaling in pancreatic cancer cells via IRS-1: In vivo evidence for an isletcancer cell axis
-
Bergmann U. Funatomi H. Kornmann M. Insulin-like growth factor II activates mitogenic signaling in pancreatic cancer cells via IRS-1: In vivo evidence for an isletcancer cell axis International Journal of Oncology 9 1996 487 492
-
(1996)
International Journal of Oncology
, vol.9
, pp. 487-492
-
-
Bergmann, U.1
Funatomi, H.2
Kornmann, M.3
-
9
-
-
0028997487
-
Insulin-like growth factor I overexpression in human pancreatic cancer: Evidence for autocrine and paracrine roles
-
Bergmann U. Funatomi H. Yokoyama M. Insulin-like growth factor I overexpression in human pancreatic cancer: Evidence for autocrine and paracrine roles Cancer Res 55 1995 2007 2011
-
(1995)
Cancer Res
, vol.55
, pp. 2007-2011
-
-
Bergmann, U.1
Funatomi, H.2
Yokoyama, M.3
-
10
-
-
0028784167
-
Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines
-
Boyer J.C. Umar A. Risinger J.I. Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines Cancer Res 1995 55 1995 6063 6070
-
(1995)
Cancer Res 1995
, vol.55
, pp. 6063-6070
-
-
Boyer, J.C.1
Umar, A.2
Risinger, J.I.3
-
11
-
-
0028176477
-
A Neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling
-
Carraway K.L. Cantley L.C. A Neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling Cell 78 1994 5 8
-
(1994)
Cell
, vol.78
, pp. 5-8
-
-
Carraway, K.L.1
Cantley, L.C.2
-
12
-
-
0027216028
-
p53 Mutations are common in pancreatic cancer and are absent in chronic pancreatitis
-
Casey G. Yamanaka Y. Friess H. p53 Mutations are common in pancreatic cancer and are absent in chronic pancreatitis Cancer Lett 69 1993 151 160
-
(1993)
Cancer Lett
, vol.69
, pp. 151-160
-
-
Casey, G.1
Yamanaka, Y.2
Friess, H.3
-
13
-
-
0028904053
-
Insulin action and the insulin signaling network
-
Cheatham B. Kahn C.R. Insulin action and the insulin signaling network Endocr Rev 16 1995 117 142
-
(1995)
Endocr Rev
, vol.16
, pp. 117-142
-
-
Cheatham, B.1
Kahn, C.R.2
-
14
-
-
0025456944
-
The possible autocrine/paracrine and endocrine roles of insulin-like growth factors of human tumors [editorial]
-
Daughaday W.H. The possible autocrine/paracrine and endocrine roles of insulin-like growth factors of human tumors [editorial] Endocrinology 127 1990 14
-
(1990)
Endocrinology
, vol.127
, pp. 14
-
-
Daughaday, W.H.1
-
16
-
-
0028941747
-
Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer
-
Di Renzo M.F. Poulsom R. Olivero M. Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer Cancer Res 55 1995 1129 1138
-
(1995)
Cancer Res
, vol.55
, pp. 1129-1138
-
-
Di Renzo, M.F.1
Poulsom, R.2
Olivero, M.3
-
17
-
-
0029146793
-
Induction of platelet-derived growth factor A and B chains and over-expression of their receptors in human pancreatic cancer
-
Ebert M. Yokoyama M. Friess H. Induction of platelet-derived growth factor A and B chains and over-expression of their receptors in human pancreatic cancer Int J Cancer 62 1995 529 535
-
(1995)
Int J Cancer
, vol.62
, pp. 529-535
-
-
Ebert, M.1
Yokoyama, M.2
Friess, H.3
-
18
-
-
0027939437
-
Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer
-
Ebert M. Yokoyama M. Friess H. Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancer Cancer Res 54 1994 5775 5778
-
(1994)
Cancer Res
, vol.54
, pp. 5775-5778
-
-
Ebert, M.1
Yokoyama, M.2
Friess, H.3
-
19
-
-
0028101982
-
Induction and expression of amphiregulin in human pancreatic cancer
-
Ebert M. Yokoyama M. Kobrin M.S. Induction and expression of amphiregulin in human pancreatic cancer Cancer Res 54 1994 3959 3962
-
(1994)
Cancer Res
, vol.54
, pp. 3959-3962
-
-
Ebert, M.1
Yokoyama, M.2
Kobrin, M.S.3
-
20
-
-
0027219671
-
Cloning of a type I TGF-ß receptor and its effect on binding to the type II receptor
-
Ebner R. Chen R.H. Shum L. Cloning of a type I TGF-ß receptor and its effect on binding to the type II receptor Science 260 1993 1344 1348
-
(1993)
Science
, vol.260
, pp. 1344-1348
-
-
Ebner, R.1
Chen, R.H.2
Shum, L.3
-
21
-
-
0027739933
-
Determination of type I receptor specificity by the type II receptors for TGF-ß and activin
-
Ebner R. Chen R.H. Lawler S. Determination of type I receptor specificity by the type II receptors for TGF-ß and activin Science 262 1993 900 902
-
(1993)
Science
, vol.262
, pp. 900-902
-
-
Ebner, R.1
Chen, R.H.2
Lawler, S.3
-
22
-
-
0029920945
-
Differential regulation of mRNA and protein by two molecular forms of basic FGF: Modulation of FGRF-1 mRNA stability
-
Estival A. Monzat V. Miguel K. Differential regulation of mRNA and protein by two molecular forms of basic FGF: Modulation of FGRF-1 mRNA stability J Biol Chem 271 1996 5663 5670
-
(1996)
J Biol Chem
, vol.271
, pp. 5663-5670
-
-
Estival, A.1
Monzat, V.2
Miguel, K.3
-
23
-
-
0025727898
-
Transforming growth factor ßl (TGF-ßl) induced neutrophil recruitment to synovial tissues: Implications for the TGF-ß-driven synovial inflammation and hyperplasia
-
Fava R.A. Olsen N.J. Postlethwaite A.E. Transforming growth factor ßl (TGF-ßl) induced neutrophil recruitment to synovial tissues: Implications for the TGF- ß -driven synovial inflammation and hyperplasia J Exp Med 173 1993 1121 1129
-
(1993)
J Exp Med
, vol.173
, pp. 1121-1129
-
-
Fava, R.A.1
Olsen, N.J.2
Postlethwaite, A.E.3
-
24
-
-
0027295352
-
Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factorlike growth factor/diphteria toxin receptor
-
Fen Z. Dhadly M.S. Yoshizumi M. Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factorlike growth factor/diphteria toxin receptor Biochemistry 32 1993 7932 7938
-
(1993)
Biochemistry
, vol.32
, pp. 7932-7938
-
-
Fen, Z.1
Dhadly, M.S.2
Yoshizumi, M.3
-
25
-
-
0027332995
-
Cloning of a TGF-ß type I receptor that forms a heteromeric complex with the TGF-ß type II receptor
-
Franzen P. ten Dijke P. Ichijo H. Cloning of a TGF-ß type I receptor that forms a heteromeric complex with the TGF-ß type II receptor Cell 75 1993 681 692
-
(1993)
Cell
, vol.75
, pp. 681-692
-
-
Franzen, P.1
ten Dijke, P.2
Ichijo, H.3
-
26
-
-
85119787807
-
A novel mutation of the TGF-ß receptor type II gene contributes to the tumorigenic properties of the human pancreatic cancer cell line MIA PaCA-2
-
Freeman J. Ahmed M. Kolaparthi V. A novel mutation of the TGF-ß receptor type II gene contributes to the tumorigenic properties of the human pancreatic cancer cell line MIA PaCA-2 AACR Proceedings 38 1997 65A
-
(1997)
AACR Proceedings
, vol.38
, pp. 65A
-
-
Freeman, J.1
Ahmed, M.2
Kolaparthi, V.3
-
27
-
-
0028296244
-
Cripto, a member of the epidermal growth factor family, is over-expressed in human pancreatic cancer and chronic pancreatitis
-
Friess H. Yamanaka Y. Büchler M. Cripto, a member of the epidermal growth factor family, is over-expressed in human pancreatic cancer and chronic pancreatitis Int J Cancer 56 1994 668 674
-
(1994)
Int J Cancer
, vol.56
, pp. 668-674
-
-
Friess, H.1
Yamanaka, Y.2
Büchler, M.3
-
28
-
-
0027131252
-
Enhanced expression of transforming growth factor-beta isoforms in human pancreatic cancer correlates with decreased survival
-
Friess H. Yamanaka Y. Büchler M. Enhanced expression of transforming growth factor-beta isoforms in human pancreatic cancer correlates with decreased survival Gastroenterology 105 1993 1846 1856
-
(1993)
Gastroenterology
, vol.105
, pp. 1846-1856
-
-
Friess, H.1
Yamanaka, Y.2
Büchler, M.3
-
29
-
-
0027195937
-
Enhanced expression of the type II transforming growth factor ßreceptor in human pancreatic cancer cells without alteration of type III receptor expression
-
Friess H. Yamanaka Y. Büchler M. Enhanced expression of the type II transforming growth factor ßreceptor in human pancreatic cancer cells without alteration of type III receptor expression Cancer Res 53 1993 2704 2707
-
(1993)
Cancer Res
, vol.53
, pp. 2704-2707
-
-
Friess, H.1
Yamanaka, Y.2
Büchler, M.3
-
30
-
-
0028799821
-
Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression
-
Friess H. Yamanaka Y. Kobrin M.S. Enhanced erbB-3 expression in human pancreatic cancer correlates with tumor progression Clinical Cancer Research 1 1995 1413 1420
-
(1995)
Clinical Cancer Research
, vol.1
, pp. 1413-1420
-
-
Friess, H.1
Yamanaka, Y.2
Kobrin, M.S.3
-
31
-
-
0030740155
-
Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor targeted therapy
-
Funatomi H. Itakura J. Ishiwata T. Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor targeted therapy Int J Cancer 72 1997 512 517
-
(1997)
Int J Cancer
, vol.72
, pp. 512-517
-
-
Funatomi, H.1
Itakura, J.2
Ishiwata, T.3
-
32
-
-
0025281396
-
daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase
-
Georgi L.L. Albert P.S. Riddle D.L. daf- 1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase Cell 61 1990 635 645
-
(1990)
Cell
, vol.61
, pp. 635-645
-
-
Georgi, L.L.1
Albert, P.S.2
Riddle, D.L.3
-
33
-
-
0027050480
-
Complexity of FGF receptors: Genetic basis for structural diversity and functional specificity
-
Givol D. Yayon A. Complexity of FGF receptors: Genetic basis for structural diversity and functional specificity FASEB J 6 1992 336 339
-
(1992)
FASEB J
, vol.6
, pp. 336-339
-
-
Givol, D.1
Yayon, A.2
-
34
-
-
0029129816
-
Increased risk of pancreatic cancer in melanoma-prone kindreds with pl6INK4 mutations
-
Goldstein A.M. Fraser M.C. Struewing J.P. Increased risk of pancreatic cancer in melanoma-prone kindreds with pl6INK4 mutations N Engl J Med 333 1995 970 974
-
(1995)
N Engl J Med
, vol.333
, pp. 970-974
-
-
Goldstein, A.M.1
Fraser, M.C.2
Struewing, J.P.3
-
35
-
-
0024851629
-
Expression of transforming growth factor a in normal human adult kidney and enhanced expression of transforming growth factors α and - ß1 in renal cell carcinoma
-
Gomella L.G. Sargent E.R. Wade T.P. Expression of transforming growth factor a in normal human adult kidney and enhanced expression of transforming growth factors α and - ß1 in renal cell carcinoma Cancer Res 49 1989 6972 6975
-
(1989)
Cancer Res
, vol.49
, pp. 6972-6975
-
-
Gomella, L.G.1
Sargent, E.R.2
Wade, T.P.3
-
36
-
-
0027053058
-
Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer
-
Gorsch S.M. Memoli V.A. Stukel T.A. Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer Cancer Res 52 1992 6949 6952
-
(1992)
Cancer Res
, vol.52
, pp. 6949-6952
-
-
Gorsch, S.M.1
Memoli, V.A.2
Stukel, T.A.3
-
37
-
-
0024333967
-
High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas
-
Grunewald K. Lyons J. Frohlich A. High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas Int J Cancer 43 1989 1037 1041
-
(1989)
Int J Cancer
, vol.43
, pp. 1037-1041
-
-
Grunewald, K.1
Lyons, J.2
Frohlich, A.3
-
38
-
-
0023626809
-
Cancer of the pancreas: 50 years of surgery
-
Gudjonsson B. Cancer of the pancreas: 50 years of surgery Cancer 60 1987 2284 2303
-
(1987)
Cancer
, vol.60
, pp. 2284-2303
-
-
Gudjonsson, B.1
-
39
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn S.A. Schutte M. Shansul Hoque A.T.M. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1 Science 268 1996 350 353
-
(1996)
Science
, vol.268
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Shansul Hoque, A.T.M.3
-
40
-
-
0028275239
-
The gradient of basic fibroblast growth factor concentration in human pancreatic cancer cell invasion
-
Hasegqawa Y. Takada M. Yamamot M. The gradient of basic fibroblast growth factor concentration in human pancreatic cancer cell invasion Biochem Biophys Res Commun 200 1994 1435 1439
-
(1994)
Biochem Biophys Res Commun
, vol.200
, pp. 1435-1439
-
-
Hasegqawa, Y.1
Takada, M.2
Yamamot, M.3
-
41
-
-
0024495948
-
Regulation of cell adhesion receptors by transforming growth factor β
-
Heino J. Ignotz R.A. Hemler M.E. Regulation of cell adhesion receptors by transforming growth factor β J Biol Chem 264 1989 380 390
-
(1989)
J Biol Chem
, vol.264
, pp. 380-390
-
-
Heino, J.1
Ignotz, R.A.2
Hemler, M.E.3
-
42
-
-
0018564970
-
A comparative study of the portal vessels connecting the endocrine and exocrine pancreas, with a discussion of some functional implications
-
Henderson J.R. Daniel P.M. A comparative study of the portal vessels connecting the endocrine and exocrine pancreas, with a discussion of some functional implications Quarterly Journal of Experimental Physiology and Cognitive Medical Sciences 64 1979 267 275
-
(1979)
Quarterly Journal of Experimental Physiology and Cognitive Medical Sciences
, vol.64
, pp. 267-275
-
-
Henderson, J.R.1
Daniel, P.M.2
-
43
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes R.O. Integrins: Versatility, modulation, and signaling in cell adhesion Cell 69 1992 11 19
-
(1992)
Cell
, vol.69
, pp. 11-19
-
-
Hynes, R.O.1
-
44
-
-
85119807630
-
-
Ishiwata T, Bergmann U, Kornmann M, et al: Altered expression of insulin-like growth factor II receptor in human pancreatic cancer. Pancreas, in press
-
-
-
-
45
-
-
85038531556
-
KGF and its receptor are co-expressed in human pancreatic cancer
-
Ishiwata T. Friess H. Büchler M.W. KGF and its receptor are co-expressed in human pancreatic cancer Pancreas 13 1996 440A
-
(1996)
Pancreas
, vol.13
, pp. 440A
-
-
Ishiwata, T.1
Friess, H.2
Büchler, M.W.3
-
46
-
-
0026406073
-
Elevated levels of transforming growth factor 1 messenger RNA and its polypeptide in human hepatocellular carcinoma
-
Ito N. Kawata S. Tamura S. Elevated levels of transforming growth factor 1 messenger RNA and its polypeptide in human hepatocellular carcinoma Cancer Res 51 1991 4080 4083
-
(1991)
Cancer Res
, vol.51
, pp. 4080-4083
-
-
Ito, N.1
Kawata, S.2
Tamura, S.3
-
47
-
-
0026649742
-
Fibroblast growth factor receptor tyrosine kinases: Molecular analysis and signal transduction
-
Jaye M. Schlessinger J. Dionne C. Fibroblast growth factor receptor tyrosine kinases: Molecular analysis and signal transduction Biochim Biophys Acta 1135 1992 185 199
-
(1992)
Biochim Biophys Acta
, vol.1135
, pp. 185-199
-
-
Jaye, M.1
Schlessinger, J.2
Dionne, C.3
-
48
-
-
0025895774
-
TGF-βl and TGF-β2 are potent growth regulators for low-grade and malignant gliomas in vitro: Evidence in support of an autocrine hypothesis
-
Jennings M.T. Maciunas R.J. Carver R. TGF-βl and TGF-β2 are potent growth regulators for low-grade and malignant gliomas in vitro: Evidence in support of an autocrine hypothesis Int J Cancer 49 1991 129 139
-
(1991)
Int J Cancer
, vol.49
, pp. 129-139
-
-
Jennings, M.T.1
Maciunas, R.J.2
Carver, R.3
-
49
-
-
0027344852
-
Structural and functional diversity in the FGF receptor multigene family
-
Johnson D.E. Williams L.T. Structural and functional diversity in the FGF receptor multigene family Adv Cancer Res 60 1993 1 18
-
(1993)
Adv Cancer Res
, vol.60
, pp. 1-18
-
-
Johnson, D.E.1
Williams, L.T.2
-
50
-
-
0026720594
-
Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon
-
Johnson G.R. Saeki T. Gordon A.W. Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon J Cell Biol 118 1992 741 751
-
(1992)
J Cell Biol
, vol.118
, pp. 741-751
-
-
Johnson, G.R.1
Saeki, T.2
Gordon, A.W.3
-
51
-
-
0028242737
-
Loss of receptors for transforming growth factor β in human T cell malignancies
-
Kadin M.E. Cavaille-Coll M.W. Gertz R. Loss of receptors for transforming growth factor β in human T cell malignancies Proc Natl Acad Sci U S A 91 1994 6002 6006
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 6002-6006
-
-
Kadin, M.E.1
Cavaille-Coll, M.W.2
Gertz, R.3
-
52
-
-
0030048263
-
Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells
-
Kim I.Y. Ahn H.J. Zelner D.J. Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells Cancer Res 56 1996 44 48
-
(1996)
Cancer Res
, vol.56
, pp. 44-48
-
-
Kim, I.Y.1
Ahn, H.J.2
Zelner, D.J.3
-
53
-
-
0028180315
-
The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
-
Kingsley D.M. The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms Genes Dev 8 1994 133 146
-
(1994)
Genes Dev
, vol.8
, pp. 133-146
-
-
Kingsley, D.M.1
-
54
-
-
0028111134
-
Induction and expression of heparin-binding EGF-like growth factor in human pancreatic cancer
-
Kobrin M.S. Funatomi H. Friess H. Induction and expression of heparin-binding EGF-like growth factor in human pancreatic cancer Biochem Biophys Res Commun 202 1994 1705 1709
-
(1994)
Biochem Biophys Res Commun
, vol.202
, pp. 1705-1709
-
-
Kobrin, M.S.1
Funatomi, H.2
Friess, H.3
-
55
-
-
0027365931
-
Aberrant expression of the type I fibroblast growth factor receptor in human pancreatic adenocarcinomas
-
Kobrin M.S. Yamanaka Y. Friess H. Aberrant expression of the type I fibroblast growth factor receptor in human pancreatic adenocarcinomas Cancer Res 53 1993 4741 4744
-
(1993)
Cancer Res
, vol.53
, pp. 4741-4744
-
-
Kobrin, M.S.1
Yamanaka, Y.2
Friess, H.3
-
56
-
-
0002930853
-
Normal function of the endocrine pancreas
-
Korc M. Normal function of the endocrine pancreas Go V.L.W. DiMagno E.P. Gardner J.D. The Pancreas: Biology, Pathobiology and Disease 1993 Raven Press New York 751 758
-
(1993)
, pp. 751-758
-
-
Korc, M.1
-
57
-
-
0026462778
-
Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha
-
Korc M. Chandrasekar B. Yamanaka Y. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha J Clin Invest 90 1992 1352 1360
-
(1992)
J Clin Invest
, vol.90
, pp. 1352-1360
-
-
Korc, M.1
Chandrasekar, B.2
Yamanaka, Y.3
-
58
-
-
0030824603
-
Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: Evidence for autocrine and paracrine actions
-
Kornmann M. Ishiwata T. Beger H.G. Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: Evidence for autocrine and paracrine actions Oncogene 15 1997 1417 1424
-
(1997)
Oncogene
, vol.15
, pp. 1417-1424
-
-
Kornmann, M.1
Ishiwata, T.2
Beger, H.G.3
-
59
-
-
0026472953
-
The erbB-3 gene in human pancreatic cancer
-
Lemoine N.R. Lobresco M. Leung H. The erbB-3 gene in human pancreatic cancer J Pathol 168 1992 269 273
-
(1992)
J Pathol
, vol.168
, pp. 269-273
-
-
Lemoine, N.R.1
Lobresco, M.2
Leung, H.3
-
60
-
-
0031587697
-
Insulin-like growth factors
-
Le Roith D. Insulin-like growth factors N Engl J Med 336 1997 633 640
-
(1997)
N Engl J Med
, vol.336
, pp. 633-640
-
-
Le Roith, D.1
-
61
-
-
0027960891
-
Expression and functional activity of fibroblast growth factors and their receptors in human pancreatic cancer
-
Leung H.Y. Gullick W.J. Lemoine N.R. Expression and functional activity of fibroblast growth factors and their receptors in human pancreatic cancer Int J Cancer 59 1994 667 675
-
(1994)
Int J Cancer
, vol.59
, pp. 667-675
-
-
Leung, H.Y.1
Gullick, W.J.2
Lemoine, N.R.3
-
62
-
-
0026537831
-
Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase
-
Lin H.Y. Wang X.-F. Ng-Eaton E. Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase Cell 68 1992 775 785
-
(1992)
Cell
, vol.68
, pp. 775-785
-
-
Lin, H.Y.1
Wang, X.-F.2
Ng-Eaton, E.3
-
63
-
-
0026576726
-
Insulin-like growth factors and cancer
-
Macaulay V.M. Insulin-like growth factors and cancer Br J Cancer 65 1992 311 320
-
(1992)
Br J Cancer
, vol.65
, pp. 311-320
-
-
Macaulay, V.M.1
-
64
-
-
0030604542
-
TGF-beta signaling: Receptors, transducers, and Mad proteins
-
Massagué J. TGF-beta signaling: Receptors, transducers, and Mad proteins Cell 85 1996 947 950
-
(1996)
Cell
, vol.85
, pp. 947-950
-
-
Massagué, J.1
-
66
-
-
0027530106
-
Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system
-
Marchionni M.A. Goodearl A.D.J. Chen M.S. Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system Nature 362 1993 312 318
-
(1993)
Nature
, vol.362
, pp. 312-318
-
-
Marchionni, M.A.1
Goodearl, A.D.J.2
Chen, M.S.3
-
67
-
-
0029066689
-
Inactivation of the TGF-β type II receptor in colon cancer cells with microsatellite instability
-
Markowitz S. Wang J. Meyerhoff L. Inactivation of the TGF-β type II receptor in colon cancer cells with microsatellite instability Science 268 1995 1336 1338
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Meyerhoff, L.3
-
68
-
-
0028088073
-
The ins and outs of fibroblast growth factors
-
Mason I.J. The ins and outs of fibroblast growth factors Cell 78 1994 547 552
-
(1994)
Cell
, vol.78
, pp. 547-552
-
-
Mason, I.J.1
-
69
-
-
0028785602
-
A transforming growth factor-β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability
-
Meyerhoff L.L. Parsons R. Kim A-J A transforming growth factor-β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability Cancer Res 55 1995 5545 5547
-
(1995)
Cancer Res
, vol.55
, pp. 5545-5547
-
-
Meyerhoff, L.L.1
Parsons, R.2
Kim, A-J3
-
70
-
-
0026570847
-
Determination of ligand-binding specificity by alternative splicing: Two distinct growth factor receptors encoded by a single gene
-
Miki T. Bottaro D.P. Fleming T.P. Determination of ligand-binding specificity by alternative splicing: Two distinct growth factor receptors encoded by a single gene Proc Natl Acad Sci USA 89 1992 246 250
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 246-250
-
-
Miki, T.1
Bottaro, D.P.2
Fleming, T.P.3
-
71
-
-
0026808908
-
The insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor mediates IGF-II-induced motility in human rhabdomyosarcoma cells
-
Minniti C.P. Kohn E.C. Grubb J.H. The insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor mediates IGF-II-induced motility in human rhabdomyosarcoma cells J Biol Chem 267 1992 9000 9004
-
(1992)
J Biol Chem
, vol.267
, pp. 9000-9004
-
-
Minniti, C.P.1
Kohn, E.C.2
Grubb, J.H.3
-
72
-
-
0026732702
-
Isolation and characterization of activin receptor from mouse embryonal carcinoma cells
-
Nakamura T. Sugino K. Kurosawa N. Isolation and characterization of activin receptor from mouse embryonal carcinoma cells J Biol Chem 267 1992 18924 18928
-
(1992)
J Biol Chem
, vol.267
, pp. 18924-18928
-
-
Nakamura, T.1
Sugino, K.2
Kurosawa, N.3
-
73
-
-
0002007794
-
The insulin-like growth factor II/mannose 6-phosphate receptor
-
Nissley P. Kiess W. Sklar M.M. The insulin-like growth factor II/mannose 6-phosphate receptor Le Roith D. Insulin-like Growth Factors: Molecular and Cellular Aspects 1991 CRC Press Boca Raton, FL 111 150
-
(1991)
, pp. 111-150
-
-
Nissley, P.1
Kiess, W.2
Sklar, M.M.3
-
74
-
-
0023162479
-
Two forms of transforming growth factor-β distinguished by multipotential haematopoetic progenitor cells
-
Ohta M. Greenberger J.S. Anklesaria P. Two forms of transforming growth factor-β distinguished by multipotential haematopoetic progenitor cells Nature 329 1987 539 543
-
(1987)
Nature
, vol.329
, pp. 539-543
-
-
Ohta, M.1
Greenberger, J.S.2
Anklesaria, P.3
-
75
-
-
15844368097
-
Receptor specificity of the fibroblast growth factor family
-
Ornitz D.M. Xu J. Colvin J.S. Receptor specificity of the fibroblast growth factor family J Biol Chem 271 1996 15292 15297
-
(1996)
J Biol Chem
, vol.271
, pp. 15292-15297
-
-
Ornitz, D.M.1
Xu, J.2
Colvin, J.S.3
-
76
-
-
0028330331
-
Neutrophil chemotaxis in response to TGF-β isoforms (TGF-βl, TGF-β2, TGF-β3) is mediated by fibronectin
-
Parekh T. Saxena B. Reibman J. Neutrophil chemotaxis in response to TGF-β isoforms (TGF-βl, TGF-β2, TGF-β3) is mediated by fibronectin J Immunol 152 1994 2456 2461
-
(1994)
J Immunol
, vol.152
, pp. 2456-2461
-
-
Parekh, T.1
Saxena, B.2
Reibman, J.3
-
77
-
-
0028556486
-
Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric cancer cells: Correlation with sensitivity to growth inhibition by TGF-β
-
Park K. Kim S-J Bang Y-J Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric cancer cells: Correlation with sensitivity to growth inhibition by TGF-β Proc Natl Acad Sci U S A 91 1994 8772 8776
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 8772-8776
-
-
Park, K.1
Kim, S-J2
Bang, Y-J3
-
79
-
-
0026776424
-
Isolation of the Neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells
-
Peles E. Bacus S.S. Koski R.A. Isolation of the Neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells Cell 69 1992 205 216
-
(1992)
Cell
, vol.69
, pp. 205-216
-
-
Peles, E.1
Bacus, S.S.2
Koski, R.A.3
-
80
-
-
0025266694
-
The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity
-
Plowman G.D. Green J.M. McDonald V.L. The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity Mol Cell Biol 10 1990 1969 1981
-
(1990)
Mol Cell Biol
, vol.10
, pp. 1969-1981
-
-
Plowman, G.D.1
Green, J.M.2
McDonald, V.L.3
-
81
-
-
0026487597
-
The type 1 (EGFR-related) family of growth factor receptors and their ligands
-
Prigent S.A. Lemoine N.R. The type 1 (EGFR-related) family of growth factor receptors and their ligands Prog Growth Factor Res 4 1992 1 24
-
(1992)
Prog Growth Factor Res
, vol.4
, pp. 1-24
-
-
Prigent, S.A.1
Lemoine, N.R.2
-
82
-
-
0025637296
-
Mesoderm induction in Xenopus laevis distinguishes between the various TGF-β isoforms
-
Roberts A.B. Kondaiah P. Rosa F. Mesoderm induction in Xenopus laevis distinguishes between the various TGF-β isoforms Growth Factors 3 1990 227 237
-
(1990)
Growth Factors
, vol.3
, pp. 227-237
-
-
Roberts, A.B.1
Kondaiah, P.2
Rosa, F.3
-
83
-
-
0028098065
-
Transforming growth factor-beta 1 and mannose 6-phosphate/insulin-like growth factor II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat
-
Saperstein L.A. Jirtle R.L. Farouk M. Transforming growth factor-beta 1 and mannose 6-phosphate/insulin-like growth factor II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat Hepatology 19 1994 412 417
-
(1994)
Hepatology
, vol.19
, pp. 412-417
-
-
Saperstein, L.A.1
Jirtle, R.L.2
Farouk, M.3
-
84
-
-
0027279176
-
How receptor tyrosine kinases activate Ras.
-
Schlessinger J. How receptor tyrosine kinases activate Ras. Trends Biochem Sci 18 1993 273 275
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 273-275
-
-
Schlessinger, J.1
-
85
-
-
0026793456
-
Growth factor signaling by receptor tyrosine kinases
-
Schlessinger J. Ullrich A. Growth factor signaling by receptor tyrosine kinases Neuron 9 1992 383 391
-
(1992)
Neuron
, vol.9
, pp. 383-391
-
-
Schlessinger, J.1
Ullrich, A.2
-
86
-
-
0029041032
-
Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region
-
Schutte M. da Costa L.T. Hahn S.A. Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region Proc Natl Acad Sci USA 92 1995 5950 5954
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5950-5954
-
-
Schutte, M.1
da Costa, L.T.2
Hahn, S.A.3
-
87
-
-
0027400724
-
Betacellulin: A mitogen from pancreatic b cell tumors
-
Shing Y. Christofori D. Hanahan D. Betacellulin: A mitogen from pancreatic b cell tumors Science 259 1993 1604 1607
-
(1993)
Science
, vol.259
, pp. 1604-1607
-
-
Shing, Y.1
Christofori, D.2
Hanahan, D.3
-
88
-
-
0028842474
-
Increased expression of keratinocyte growth factor in human pancreatic cancer
-
Siddiqi I. Funatomi H. Kobrin M.S. Increased expression of keratinocyte growth factor in human pancreatic cancer Biochem Biophys Res Commun 215 1995 309 315
-
(1995)
Biochem Biophys Res Commun
, vol.215
, pp. 309-315
-
-
Siddiqi, I.1
Funatomi, H.2
Kobrin, M.S.3
-
89
-
-
0023449818
-
Production of transforming growth factor a in human pancreatic cancer cells: Evidence for a superagonist autocrine cycle
-
Smith J.J. Derynck R. Kore M. Production of transforming growth factor a in human pancreatic cancer cells: Evidence for a superagonist autocrine cycle Proc Natl Acad Sci USA 84 1987 7567 7570
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7567-7570
-
-
Smith, J.J.1
Derynck, R.2
Kore, M.3
-
90
-
-
0028302018
-
ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
-
Soltoff S.P. Carraway K.L. III Prigent S.A. ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor Mol Cell Biol 14 1994 3550 3558
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3550-3558
-
-
Soltoff, S.P.1
Carraway, K.L.2
Prigent, S.A.3
-
91
-
-
0026445528
-
Transforming growth factor-β: Recent progress and new challenges
-
Sporn M.B. Roberts A.B. Transforming growth factor-β: Recent progress and new challenges J Cell Biol 119 1992 1017 1021
-
(1992)
J Cell Biol
, vol.119
, pp. 1017-1021
-
-
Sporn, M.B.1
Roberts, A.B.2
-
92
-
-
0028295762
-
Characterization of type I receptors for transforming growth factor beta and activin
-
ten Dijke P. Yamashita H. Icjijo H. Characterization of type I receptors for transforming growth factor beta and activin Science 264 1994 101 104
-
(1994)
Science
, vol.264
, pp. 101-104
-
-
ten Dijke, P.1
Yamashita, H.2
Icjijo, H.3
-
93
-
-
0029561565
-
Molecular cloning of mouse epiregulin, a novel epidermal growth factor-related protein, expressed in the early stage of development
-
Toyoda H. Komurasaki T. Ikeda Y. Molecular cloning of mouse epiregulin, a novel epidermal growth factor-related protein, expressed in the early stage of development FEBS Lett 377 1995 403 407
-
(1995)
FEBS Lett
, vol.377
, pp. 403-407
-
-
Toyoda, H.1
Komurasaki, T.2
Ikeda, Y.3
-
94
-
-
0004825735
-
Microsatellite instability and the status of transforming growth factor-β type II gene in pancreatic adenocarcinoma
-
Venkatasubbarao K. Ahmed M.M. Swiderski C. Microsatellite instability and the status of transforming growth factor-β type II gene in pancreatic adenocarcinoma AACR Proceedings 38 1997 149A
-
(1997)
AACR Proceedings
, vol.38
, pp. 149A
-
-
Venkatasubbarao, K.1
Ahmed, M.M.2
Swiderski, C.3
-
95
-
-
0030483560
-
Expression of a truncated EGF receptor is associated with inhibition of pancreatic cancer cell growth and enhanced sensitivity to cisplatinum
-
Wagner M. Cao T. Lopez M.E. Expression of a truncated EGF receptor is associated with inhibition of pancreatic cancer cell growth and enhanced sensitivity to cisplatinum Int J Cancer 68 1996 782 787
-
(1996)
Int J Cancer
, vol.68
, pp. 782-787
-
-
Wagner, M.1
Cao, T.2
Lopez, M.E.3
-
96
-
-
0030056048
-
Reduced expression of transforming growth factor β type I receptor contributes to the malignancy of human colon carcinoma cells
-
Wang J. Han W. Zborowska E. Reduced expression of transforming growth factor β type I receptor contributes to the malignancy of human colon carcinoma cells J Biol Chem 271 1996 17366 17371
-
(1996)
J Biol Chem
, vol.271
, pp. 17366-17371
-
-
Wang, J.1
Han, W.2
Zborowska, E.3
-
97
-
-
0025989562
-
Expression cloning and characterization of the TGF-β type III receptor
-
Wang X-F Lin H.Y. Ng-Eaton E. Expression cloning and characterization of the TGF-β type III receptor Cell 67 1991 797 805
-
(1991)
Cell
, vol.67
, pp. 797-805
-
-
Wang, X-F1
Lin, H.Y.2
Ng-Eaton, E.3
-
99
-
-
0029022221
-
GS domain mutations that constitutively activate TGF-βRl, the downstream signaling component in the TGF-β receptor complex
-
Wieser R. Wrana J.L. Massagué J. GS domain mutations that constitutively activate TGF-βRl, the downstream signaling component in the TGF-β receptor complex EMBO J 14 1995 2199 2208
-
(1995)
EMBO J
, vol.14
, pp. 2199-2208
-
-
Wieser, R.1
Wrana, J.L.2
Massagué, J.3
-
100
-
-
0026496172
-
TGF-β signals through a heteromeric protein kinase receptor complex
-
Wrana J.L. Attisano L. Carcamo J. TGF-β signals through a heteromeric protein kinase receptor complex Cell 71 1992 1003 1014
-
(1992)
Cell
, vol.71
, pp. 1003-1014
-
-
Wrana, J.L.1
Attisano, L.2
Carcamo, J.3
-
101
-
-
0028170226
-
Mechanism of activation of the TGF-β receptor
-
Wrana J.L. Attisano L. Weiser L. Mechanism of activation of the TGF-β receptor Nature 370 1994 341 347
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
Attisano, L.2
Weiser, L.3
-
102
-
-
0030974042
-
Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4
-
Wu R.Y. Zhang Y. Fen X-H Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4 Mol Cell Biol 17 1997 2521 2528
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2521-2528
-
-
Wu, R.Y.1
Zhang, Y.2
Fen, X-H3
-
103
-
-
0027435936
-
Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumor stage
-
Yamanaka Y. Friess H. Büchler M. Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumor stage Cancer Res 53 1993 5289 5296
-
(1993)
Cancer Res
, vol.53
, pp. 5289-5296
-
-
Yamanaka, Y.1
Friess, H.2
Büchler, M.3
-
104
-
-
0027293748
-
Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness
-
Yamanaka Y. Friess H. Kobrin M.S. Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness Anticancer Res 13 1993 565 570
-
(1993)
Anticancer Res
, vol.13
, pp. 565-570
-
-
Yamanaka, Y.1
Friess, H.2
Kobrin, M.S.3
-
105
-
-
0027431337
-
Overexpression of HER-2/neu oncogene in human pancreatic carcinoma
-
Yamanaka Y. Friess H. Kobrin M.S. Overexpression of HER-2 /neu oncogene in human pancreatic carcinoma Hum Pathol 24 1993 1127 1134
-
(1993)
Hum Pathol
, vol.24
, pp. 1127-1134
-
-
Yamanaka, Y.1
Friess, H.2
Kobrin, M.S.3
-
106
-
-
0030037448
-
Structure and expression of the rat mRNA encoding a novel member of the fibroblast growth factor family
-
Yamasaki M. Miyake A. Tagashira S. Structure and expression of the rat mRNA encoding a novel member of the fibroblast growth factor family J Biol Chem 271 1996 15918 15921
-
(1996)
J Biol Chem
, vol.271
, pp. 15918-15921
-
-
Yamasaki, M.1
Miyake, A.2
Tagashira, S.3
-
107
-
-
0031171216
-
The IRS-signalling system during insulin and cytokine action
-
Yenush L. White M. The IRS-signalling system during insulin and cytokine action Bioessays 19 1997 491 500
-
(1997)
Bioessays
, vol.19
, pp. 491-500
-
-
Yenush, L.1
White, M.2
-
108
-
-
0028918095
-
Amphiregulin is a potent mitogen in human pancreatic cancer cells: Correlation with patient survival
-
Yokoyama M. Ebert M. Funatomi H. Amphiregulin is a potent mitogen in human pancreatic cancer cells: Correlation with patient survival International Journal of Oncology 6 1995 625 631
-
(1995)
International Journal of Oncology
, vol.6
, pp. 625-631
-
-
Yokoyama, M.1
Ebert, M.2
Funatomi, H.3
-
109
-
-
0029147169
-
Betacellulin, a member of the epidermal growth factor family, is overexpressed in human pancreatic cancer
-
Yokoyama M. Funatomi H. Kobrin M.S. Betacellulin, a member of the epidermal growth factor family, is overexpressed in human pancreatic cancer International Journal of Oncology 7 1995 825 829
-
(1995)
International Journal of Oncology
, vol.7
, pp. 825-829
-
-
Yokoyama, M.1
Funatomi, H.2
Kobrin, M.S.3
-
110
-
-
0030933427
-
Cystein-rich FGF receptor regulates intracellular FGF-1 and FGF-2 levels
-
Zuber M.E. Zhou Z. Burrus L.W. Cystein-rich FGF receptor regulates intracellular FGF-1 and FGF-2 levels J Cell Physiol 170 1997 217 227
-
(1997)
J Cell Physiol
, vol.170
, pp. 217-227
-
-
Zuber, M.E.1
Zhou, Z.2
Burrus, L.W.3
|