Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

Journal of Biological Chemistry

Volumn 278, Issue 33, 2003, Pages 31401-31411

  Bidère, Nicolas ^a   Lorenzo, Hans K ^a   Carmona, Sylvie ^a   Laforge, Mireille ^a   Harper, Francis ^b   Dumont, Céline ^a   Senik, Anna ^a  

^a HÔPITAL PAUL BROUSSE   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDITY; CELLS; CONDENSATION;

CELL SHRINKAGE;

BIOCHEMISTRY;

APOPTOSIS INDUCING FACTOR; BAFILOMYCIN A1; CASPASE INHIBITOR; CATHEPSIN B; CATHEPSIN D; CATHEPSIN L; PEPSTATIN; PROTEIN BAX; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; RNA; SMALL INTERFERING RNA; STAUROSPORINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ASSAY; ENZYME SUBSTRATE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LYMPHOCYTE CULTURE; MITOCHONDRION; PRIORITY JOURNAL; T LYMPHOCYTE;

ANTI-BACTERIAL AGENTS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CATHEPSIN B; CATHEPSIN D; CATHEPSINS; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; CYTOSOL; DOWN-REGULATION; ENZYME INHIBITORS; FLAVOPROTEINS; HUMANS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MACROLIDES; MEMBRANE PROTEINS; MITOCHONDRIA; PEPSTATINS; PHENOTYPE; PROTEASE INHIBITORS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAUROSPORINE; T-LYMPHOCYTES;

FELIS CATUS; INSERTION SEQUENCES;

EID: 0043234207     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301911200     Document Type: Article

References (48)

1. Dumont, C., Durrbach, A., Bidere, N., Rouleau, M., Kroemer, G., Bernard, G., Hirsch, F., Charpentier, B., Susin, S. A., and Senik, A. (2000) Blood 96, 1030-1038
2. Bidere, N., and Senik, A. (2001) Apoptosis 6, 371
3. Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Snow, B. E., Brothers, G. M., Mangion, J., Jacotot, E., Costantini, P., Loeffler, M., Larochette, N., Goodlett, D. R., Aebersold, R., Siderovski, D. P., Penninger, J. M., and Kroemer, G. (1999) Nature 397, 441-446
4. Joza, N., Susin, S. A., Daugas, E., Stanford, W. L., Cho, S. K., Li, C. Y., Sasaki, T., Elia, A. J., Cheng, H. Y., Ravagnan, L., Ferri, K. F., Zamzami, N., Wakeham, A., Hakem, R., Yoshida, H., Kong, Y. Y., Mak, T. W., Zuniga-Pflucker, J. C., Kroemer, G., and Penninger, J. M. (2001) Nature 410, 549-554
5. Susin, S. A., Daugas, E., Ravagnan, L., Samejima, K., Zamzami, N., Loeffler, M., Costantini, P., Ferri, K. F., Irinopoulou, T., Prevost, M. C., Brothers, G., Mak, T. W., Penninger, J., Earnshaw, W. C., and Kroemer, G. (2000) J. Exp. Med. 192, 571-580
6. Loeffler, M., Daugas, E., Susin, S. A., Zamzami, N., Metivier, D., Nieminen, A. L., Brothers, G., Penninger, J. M., and Kroemer, G. (2001) Faseb J. 15, 758-767
7. Cregan, S. P., Fortin, A., MacLaurin, J. G., Callaghan, S. M., Cecconi, F., Yu, S. W., Dawson, T. M., Dawson, V. L., Park, D. S., Kroemer, G., and Slack, R. S. (2002) J. Cell Biol. 158, 507-517
8. Wang, X., Yang, C., Chai, J., Shi, Y., and Xue, D. (2002) Science 298, 1587-1592
9. Wolter, K. G., Hsu, Y. T., Smith, C. L., Nechushtan, A., Xi, X. G., and Youle, R. J. (1997) J. Cell Biol. 139, 1281-1292
10. Goping, I. S., Gross, A., Lavoie, J. N., Nguyen, M., Jemmerson, R., Roth, K., Korsmeyer, S. J., and Shore, G. C. (1998) J. Cell Biol. 143, 207-215
11. Gross, A., Jockel, J., Wei, M. C., and Korsmeyer, S. J. (1998) EMBO J. 17, 3878-3885
12. Antonsson, B., Montessuit, S., Sanchez, B., and Martinou, J. C. (2001) J. Biol. Chem. 276, 11615-11623
13. Nechustan, A., Smith, C. L., Hsu, Y. T., and Youle, R. J. (1999) EMBO J. 18, 2330-2341
14. Desagher, S., Osen-Sand, A., Nichols, A., Eskes, R., Montessuit, S., Lauper, S., Maundrell, K., Antonsson, B., and Martinou, J. C. (1999) J. Cell Biol. 144, 891-901
15. Eskes, R., Desagher, S., Antonsson, B., and Martinou, J. C. (2000) Mol. Cell. Biol. 20, 929-935
16. Ruffolo, S. C., Breekenridge, D. G., Nguyen, M., Goping, I. S., Gross, A., Korsmeyer, S. J., Li, H., Yuan, J., and Shore, G. C. (2000) Cell Death Differ. 7, 1101-1108
17. Khaled, A. R., Kim, K., Hofmeister, R., Muegge, K., and Durum, S. K. (1999) Proc. Natl. Acad. Sci. 96, 14476-14481
18. Tafani, M., Cohn, J. A., Karpinich, N. O., Rothman, R. J., Russo, M. A., and Farber, J. L. (2002) J. Biol. Chem. 277, 49569-49576
19. Johnson, D. E. (2000) Leukemia 14, 1695-1703
20. Turk, B., Stoka, V., Rozman-Pungercar, J., Cirman, T., Droga-Mazovec, G., Oreie, K., and Turk, V. (2002) Biol. Chem. 383, 1035-1044
21. Mathiasen, I. S., and Jaattela, M. (2002) Trends Mol. Med. 8, 212-220
22. McManus, M. T., and Sharp, P. A. (2002) Nat. Rev. Genet. 3, 737-747
23. Bidere, N., Briet, M., Durrbach, A., Dumont, C., Feldmann, J., Charpentier, B., de Saint-Basile, G., and Senik, A. (2002) J. Biol. Chem. 277, 32339-32347
24. Barrett, A. J., and Kirschke, H. (1981) Methods Enzymol. 80, 535-561
25. Kagedal, K., Johansson, U., and Ollinger, K. (2001) FASEB J. 15, 1592-1594
26. Stinchcombe, J. C., Barral, D. C., Mules, E. H., Booth, S., Hume, A. N., Machesky, L. M., Seabra, M. C., and Griffiths, G. M. (2001) J. Cell Biol. 152, 825-834
27. Hsu, Y. T., and Youle, R. J. (1998) J. Biol. Chem. 272, 10777-10783
28. Foghsgaard, L., Wissing, D., Mauch, D., Lademann, U., Bastholm, L., Boes, M., Elling, F., Leist, M., and Jaattela, M. (2001) J. Cell Biol. 153, 999-1010
29. Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. (2001) Nature 411, 494-498
30. van Loo, G., Saelens, X., van Gurp, M., MacFarlane, M., Martin, S. J., and Vandenabeele, P. (2002) Cell Death Differ. 9, 1031-1042
31. Yoshimori, T., Yamamoto, A., Moriyama, Y., Futai, M., and Tashiro, Y. (1991) J. Biol. Chem. 266, 17707-17712
32. McManus, M. T., Haines, B. B., Dillon, C. P., Whitehurst, C. E., van Parijs, L., Chen, J., and Sharp, P. A. (2002) J. Immunol. 169, 5754-5760
33. Rathmell, J. C., Lindsten, T., Zong, W. X., Cinalli, R. M., and Thompson, C. B. (2002) Nat. Immunol. 3, 932-939
34. Deiss, L. P., Galinka, H., Berissi, H., Cohen, O., and Kimchi, A. (1996) EMBO J. 15, 3661-3670
35. Isahara, K., Ohsawa, Y., Kanamori, S., Shibata, M., Waguri, S., Sato, N., Gotow, T., Watanabe, T., Momoi, T., Urase, K., Kominami, E., and Uchiyama, Y. (1999) Neuroscience 91, 233-249
36. Roberts, L. R., Adjei, P. N., and Gores, G. J. (1999) Cell Biochem. Biophys. 30, 71-88
37. Roberg, K., Kagedal, K., and Ollinger, K. (2002) Am. J. Pathol. 161, 89-96
38. Kagedal, K., Zhao, M., Svensson, I., and Brunk, U. T. (2001) Biochem. J. 359, 335-343
39. Lee, A. Y., Gulnik, S. V., and Erickson, J. W. (1998) Nat. Struct. Biol. 5, 866-871
40. Stoka, V., Turk, B., Schendel, S. L., Kim, T. H., Cirman, T., Snipas, S. J., Ellerby, L. M., Bredesen, D., Freeze, H., Abrahamson, M., Bromme, D., Krajewski, S., Reed, J. C., Yin, X. M., Turk, V., and Salvesen, G. S. (2001) J. Biol. Chem. 276, 3149-3157
41. Reiners, J. J., Caruso, J. A., Mathieu, P., Chelladurai, B., Yin, X. M., and Kessel, D. (2002) Cell Death Differ. 9, 934-944
42. Nomura, M., Shimizu, S., Sugiyama, T., narita, M., Ito, T., Matsuda, H., and Tsujimoto, Y. (2003) J. Biol. Chem. 278, 2058-2065
43. Sawada, M., Sun, W., Hayes, P., Leskov, K., Boothman, D. A., and Matsuyama, S. (2003) Nat. Cell Biol. 5, 320-329
44. Guicciardi, M. E., Deussing, J., Miyoshi, H., Bronk, S. F., Svingen, P. A., Peters, C., Kaufmann, S. H., and Gores, G. J. (2000) J. Clin. Invest. 106, 1127-1137
45. Turk, B., Turk, D., and Salvesen, G. S. (2002) Curr. Pharm. Des. 8, 1623-1637
46. Arnoult, D., Parone, P., Martinou, J. C., Antonsson, B., Estaquier, J., and Ameisen, J. C. (2002) J. Cell Biol. 159, 923-929
47. Saftig, P., Hetman, M., Schmahl, W., Weber, K., Heine, L., Mossmann, H., Koster, A., Hess, B., Evers, M., and von Figura, K. (1995) EMBO J. 14, 3599-3608
48. Klein, J. A., Longo-Guess, C. M., Rossmann, M. P., Seburn, K. L., Hurd, R. E., Frankel, W. N., Bronson, R. T., and Ackerman, S. L. (2002) Nature 419, 367-374