메뉴 건너뛰기




Volumn 35, Issue 1, 2000, Pages 1-9

Stress kinases and heat shock proteins in the pancreas: possible roles in normal function and disease

Author keywords

Hsp; MAPK; Pancreas; Stress kinase

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

EID: 0033984954     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (85)

References (73)
  • 2
    • 0031825424 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase cascades as regulators of stress responses
    • Karin M. Mitogen-activated protein kinase cascades as regulators of stress responses (review). Ann NY Acad Sci 1998;851:139-46.
    • (1998) Ann NY Acad Sci , vol.851 , pp. 139-146
    • Karin, M.1
  • 3
    • 0030703604 scopus 로고    scopus 로고
    • Regulation and function of the JNK subgroup of MAP kinases
    • Minden A, Karin M. Regulation and function of the JNK subgroup of MAP kinases (review). Biochim Biophys Acta 1997;1333:F85-104.
    • (1997) Biochim Biophys Acta , vol.1333
    • Minden, A.1    Karin, M.2
  • 4
    • 0029055812 scopus 로고
    • The small GTP-binding proteins racl and cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso OA, Chiariello M, Yu JC, Teramoto H, Crespo P, Xu N, et al. The small GTP-binding proteins racl and cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 1995;81:1137-46.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6
  • 5
    • 0027984138 scopus 로고
    • GAPs for rho-related GTPases
    • Lamarche N, Hall A. GAPs for rho-related GTPases. Trends Genet 1994;10:436-40.
    • (1994) Trends Genet , vol.10 , pp. 436-440
    • Lamarche, N.1    Hall, A.2
  • 6
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb M, Goldsmith EJJ. How MAP kinases are regulated (review). J Biol Chem 1995;270:14843-6.
    • (1995) J Biol Chem , vol.270 , pp. 14843-14846
    • Cobb, M.1    Goldsmith, E.J.J.2
  • 8
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases (review). J Biol Chem 1995;270:16483-6.
    • (1995) J Biol Chem , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 9
    • 0032928614 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase cascade: Conservation of a three-kinase module from yeast to human
    • Widmann C, Gibson S, Jarpe MB, Johnson GL. Mitogen-activated protein kinase cascade: conservation of a three-kinase module from yeast to human (review). Physiol Rev 1999;79:143-80.
    • (1999) Physiol Rev , vol.79 , pp. 143-180
    • Widmann, C.1    Gibson, S.2    Jarpe, M.B.3    Johnson, G.L.4
  • 11
    • 0030898417 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways
    • Robinson MJ, Cobb MH. Mitogen-activated protein kinase pathways (review). Curr Opin Cell Biol 1997;9:180-6.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 180-186
    • Robinson, M.J.1    Cobb, M.H.2
  • 12
    • 0027423418 scopus 로고
    • Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
    • Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev 1993;7:2135-48.
    • (1993) Genes Dev , vol.7 , pp. 2135-2148
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 13
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, et al. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 1994;76:1025-37.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5    Deng, T.6
  • 15
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • Han J, Lee JD, Bibbs L, Ulevitch RJ. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 1994;265:808-11.
    • (1994) Science , vol.265 , pp. 808-811
    • Han, J.1    Lee, J.D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 16
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994;372:739-46.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3    Gallagher, T.F.4    Kumar, S.5    Green, D.6
  • 17
    • 0028022750 scopus 로고
    • A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
    • Rouse J, Cohen P, Trigon S, Morange M, Alonso-Llamazeres A, Zamanillo D, et al. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 1994;78:1027-37.
    • (1994) Cell , vol.78 , pp. 1027-1037
    • Rouse, J.1    Cohen, P.2    Trigon, S.3    Morange, M.4    Alonso-Llamazeres, A.5    Zamanillo, D.6
  • 18
    • 0028073283 scopus 로고
    • MAPKs: New JNK expands the group
    • Davis RJ. MAPKs: new JNK expands the group (review). Trends Biochem Sci 1994;19:470-3.
    • (1994) Trends Biochem Sci , vol.19 , pp. 470-473
    • Davis, R.J.1
  • 20
    • 0032054723 scopus 로고    scopus 로고
    • Signal transduction by the c-Jun N-terminal kinase (JNK)- from inflammation to development
    • Ip YT, Davis RJ. Signal transduction by the c-Jun N-terminal kinase (JNK)- from inflammation to development. Curr Opin Cell Biol 1998;10:205-219.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 205-219
    • Ip, Y.T.1    Davis, R.J.2
  • 21
    • 0030689618 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase
    • Wu Z, Wu J, Jacinto E, Karin M. Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase. Mol Cell Biol 1997;17:7407-16.
    • (1997) Mol Cell Biol , vol.17 , pp. 7407-7416
    • Wu, Z.1    Wu, J.2    Jacinto, E.3    Karin, M.4
  • 22
  • 23
    • 0028568217 scopus 로고
    • Differential activation of ERK and JNK mitogen-activated protein kinases by Rat-1 and MEKK
    • Minden A, Lin A, McMahon M, Lange-Carter C, Derijard B, Davis RJ, et al. Differential activation of ERK and JNK mitogen-activated protein kinases by Rat-1 and MEKK. Science 1994; 266:1719-23.
    • (1994) Science , vol.266 , pp. 1719-1723
    • Minden, A.1    Lin, A.2    McMahon, M.3    Lange-Carter, C.4    Derijard, B.5    Davis, R.J.6
  • 24
    • 0028670788 scopus 로고
    • Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
    • Yan M, Dai T, Deak JC, Kyriakis JM, Zon LI, Woodgett JR, Templeton DJ. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature 1994;372: 798-800.
    • (1994) Nature , vol.372 , pp. 798-800
    • Yan, M.1    Dai, T.2    Deak, J.C.3    Kyriakis, J.M.4    Zon, L.I.5    Woodgett, J.R.6    Templeton, D.J.7
  • 25
    • 0030934694 scopus 로고    scopus 로고
    • Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway
    • Gerwins P, Blank JL, Johnson GL. Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway. J Biol Chem 1997;272:8288-95.
    • (1997) J Biol Chem , vol.272 , pp. 8288-8295
    • Gerwins, P.1    Blank, J.L.2    Johnson, G.L.3
  • 26
    • 0028924419 scopus 로고
    • Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation
    • Liu Y, Gorospe M, Yang C, Holbrook NJ. Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation. J Biol Chem 1995;270:8377-80.
    • (1995) J Biol Chem , vol.270 , pp. 8377-8380
    • Liu, Y.1    Gorospe, M.2    Yang, C.3    Holbrook, N.J.4
  • 28
    • 0031044561 scopus 로고    scopus 로고
    • MEKKs, GCKs, MEKs, PAKs, TAKs, and tpls: Upstream regulators of the c-Jun amino-terminal kinases?
    • Fanger GR, Gerwins P, Widmann C, Jarpe MB, Johnson GL. MEKKs, GCKs, MEKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases? (review). Curr Opin Genet Dev 1997;7:67-74.
    • (1997) Curr Opin Genet Dev , vol.7 , pp. 67-74
    • Fanger, G.R.1    Gerwins, P.2    Widmann, C.3    Jarpe, M.B.4    Johnson, G.L.5
  • 29
    • 0030044182 scopus 로고    scopus 로고
    • Characterization of the structure and function of a novel MAP kinase kinase (MKK6)
    • Han J, Lee JD, Jiang Y, Ei Z, Feng L, Ulevitch RJ. Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J Biol Chem 1996;271:2886-91.
    • (1996) J Biol Chem , vol.271 , pp. 2886-2891
    • Han, J.1    Lee, J.D.2    Jiang, Y.3    Ei, Z.4    Feng, L.5    Ulevitch, R.J.6
  • 30
    • 0030006618 scopus 로고    scopus 로고
    • Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade
    • Stein B, Brady H, Yang MX, Young DB, Barbosa MS. Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade. J Biol Chem 1996; 271:11427-33.
    • (1996) J Biol Chem , vol.271 , pp. 11427-11433
    • Stein, B.1    Brady, H.2    Yang, M.X.3    Young, D.B.4    Barbosa, M.S.5
  • 31
    • 0030051528 scopus 로고    scopus 로고
    • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. J Mol Cell Biol 1996;16:1247-55.
    • (1996) J Mol Cell Biol , vol.16 , pp. 1247-1255
    • Raingeaud, J.1    Whitmarsh, A.J.2    Barrett, T.3    Derijard, B.4    Davis, R.J.5
  • 32
    • 0029782176 scopus 로고    scopus 로고
    • Purification and cDNA cloning of SAPKK3. the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells
    • Cuenda A, Alonso G, Morrice N, Jones M, Meier R, Cohen P, Nebreda AR. Purification and cDNA cloning of SAPKK3. the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells. EMBO J 1996;15:4156-64.
    • (1996) EMBO J , vol.15 , pp. 4156-4164
    • Cuenda, A.1    Alonso, G.2    Morrice, N.3    Jones, M.4    Meier, R.5    Cohen, P.6    Nebreda, A.R.7
  • 33
    • 0031916832 scopus 로고    scopus 로고
    • Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6
    • Enslen H, Raingeaud J, Davis RJ. Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6. J Biol Chem 1998;273:1741-8.
    • (1998) J Biol Chem , vol.273 , pp. 1741-1748
    • Enslen, H.1    Raingeaud, J.2    Davis, R.J.3
  • 34
    • 14444281569 scopus 로고    scopus 로고
    • Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK, JNK and p38 signaling pathways
    • Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK, JNK and p38 signaling pathways. Science 1997;275:90-4.
    • (1997) Science , vol.275 , pp. 90-94
    • Ichijo, H.1    Nishida, E.2    Irie, K.3    Ten Dijke, P.4    Saitoh, M.5    Moriguchi, T.6
  • 35
    • 0033015379 scopus 로고    scopus 로고
    • Novel molecular mediators in the pathway connecting G-protein-coupled receptors to MAP kinase cascades
    • Murga C, Fukuhara S, Gutkind S. Novel molecular mediators in the pathway connecting G-protein-coupled receptors to MAP kinase cascades. Trends Endocrinol Metabol 1999;10:122-7.
    • (1999) Trends Endocrinol Metabol , vol.10 , pp. 122-127
    • Murga, C.1    Fukuhara, S.2    Gutkind, S.3
  • 36
    • 0032508660 scopus 로고    scopus 로고
    • A role for the p38 mitogen-activated protein kinase/ Hsp27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini
    • Schäfer C, Ross SE, Bragado MJ, Groblewski GE, Ernst SE, Williams JA. A role for the p38 mitogen-activated protein kinase/ Hsp27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini. J Biol Chem 1998;273:24173-80.
    • (1998) J Biol Chem , vol.273 , pp. 24173-24180
    • Schäfer, C.1    Ross, S.E.2    Bragado, M.J.3    Groblewski, G.E.4    Ernst, S.E.5    Williams, J.A.6
  • 37
    • 0031056783 scopus 로고    scopus 로고
    • Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27
    • Guay J, Lambert H, Gingras-Breton G, Lavoie J, Huot J, Landry J. Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27. J Cell Sci 1997;110:357-68.
    • (1997) J Cell Sci , vol.110 , pp. 357-368
    • Guay, J.1    Lambert, H.2    Gingras-Breton, G.3    Lavoie, J.4    Huot, J.5    Landry, J.6
  • 38
    • 0032535245 scopus 로고    scopus 로고
    • Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
    • Morimoto RI. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Dev 1998;12:3788-96.
    • (1998) Genes Dev , vol.12 , pp. 3788-3796
    • Morimoto, R.I.1
  • 39
    • 0027925653 scopus 로고
    • Heat shock proteins functioning as molecular chaperones: Their roles in normal and stressed cells
    • Welch WJ. Heat shock proteins functioning as molecular chaperones: their roles in normal and stressed cells (review). Philos Trans R Soc Land B Biol Sci 1993;339:327-33.
    • (1993) Philos Trans R Soc Land B Biol Sci , vol.339 , pp. 327-333
    • Welch, W.J.1
  • 40
    • 0023647142 scopus 로고
    • Protein transport. Signals and salvage sequences
    • Warren G. Protein transport. Signals and salvage sequences. Nature 1987;327:17-8.
    • (1987) Nature , vol.327 , pp. 17-18
    • Warren, G.1
  • 41
    • 0032440847 scopus 로고    scopus 로고
    • Heat shock proteins: Regulators of stress response and apoptosis
    • Samali A, Orrenius S. Heat shock proteins: regulators of stress response and apoptosis (review). Cell Stress Chaperones 1998;3: 228-36.
    • (1998) Cell Stress Chaperones , vol.3 , pp. 228-236
    • Samali, A.1    Orrenius, S.2
  • 42
    • 0026584271 scopus 로고
    • Protein folding in the cell
    • Gething MJ, Sambrook J. Protein folding in the cell. Nature 1992;355:33-45.
    • (1992) Nature , vol.355 , pp. 33-45
    • Gething, M.J.1    Sambrook, J.2
  • 43
    • 0027391629 scopus 로고
    • Small heat shock proteins are molecular chaperones
    • Jakob U, Gaestel M, Engel K, Buchner J. Small heat shock proteins are molecular chaperones. J Biol Chem 1993;268:1517-20.
    • (1993) J Biol Chem , vol.268 , pp. 1517-1520
    • Jakob, U.1    Gaestel, M.2    Engel, K.3    Buchner, J.4
  • 44
    • 0027957356 scopus 로고
    • Stress- and mitogen-induced phosphorylation of the small heat shock protein Hsp25 by MAPKAP kinase-2 is not essential for chaperone properties and cellular thermoresistance
    • Knauf U, Jakob U, Engel K, Buchner J, Gaestel M. Stress- and mitogen-induced phosphorylation of the small heat shock protein Hsp25 by MAPKAP kinase-2 is not essential for chaperone properties and cellular thermoresistance. EMBO J 1994; 13:54-60.
    • (1994) EMBO J , vol.13 , pp. 54-60
    • Knauf, U.1    Jakob, U.2    Engel, K.3    Buchner, J.4    Gaestel, M.5
  • 45
    • 0028071812 scopus 로고
    • Phosphorylation and supramolecular organization of murine small heat shock protein Hsp25 abolish its actin polymerization-inhibiting activity
    • Benndorf R, Hayess K, Ryazantsev S, Wieske M, Behlke J, Lusch G. Phosphorylation and supramolecular organization of murine small heat shock protein Hsp25 abolish its actin polymerization-inhibiting activity. J Biol Chem 1994;269:20780-4.
    • (1994) J Biol Chem , vol.269 , pp. 20780-20784
    • Benndorf, R.1    Hayess, K.2    Ryazantsev, S.3    Wieske, M.4    Behlke, J.5    Lusch, G.6
  • 46
    • 0031849099 scopus 로고    scopus 로고
    • Small heat-shock family: Function in health and disease
    • Welsh MJ, Gaestel M. Small heat-shock family: function in health and disease. Ann NY Acad Sci 1998;851:28-35.
    • (1998) Ann NY Acad Sci , vol.851 , pp. 28-35
    • Welsh, M.J.1    Gaestel, M.2
  • 47
    • 0029864407 scopus 로고    scopus 로고
    • Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo
    • Dabrowski A, Grady T, Logsdon CD, Williams JA. Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo. J Biol Chem 1996;271:5686-90.
    • (1996) J Biol Chem , vol.271 , pp. 5686-5690
    • Dabrowski, A.1    Grady, T.2    Logsdon, C.D.3    Williams, J.A.4
  • 48
    • 0028156378 scopus 로고
    • Cholecystokinin rapidly activates mitogen-activated protein kinase in rat pancreatic acini
    • Duan R-D, Williams JA. Cholecystokinin rapidly activates mitogen-activated protein kinase in rat pancreatic acini. Am J Physiol 1994;267:G401-8.
    • (1994) Am J Physiol , vol.267
    • Duan, R.-D.1    Williams, J.A.2
  • 49
    • 0028835482 scopus 로고
    • Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini
    • Duan R-D, Zheng C-F, Guan K-L, Williams JA. Activation of MAP kinase kinase (MEK) and Ras by cholecystokinin in rat pancreatic acini. Am J Physiol 1995;268:G1060-5.
    • (1995) Am J Physiol , vol.268
    • Duan, R.-D.1    Zheng, C.-F.2    Guan, K.-L.3    Williams, J.A.4
  • 50
    • 0030720786 scopus 로고    scopus 로고
    • Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells
    • Dabrowski A, Groblewski GE, Schäfer C, Guan K-L, Williams JA. Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells. Am J Physiol 1997;273:C1472-9.
    • (1997) Am J Physiol , vol.273
    • Dabrowski, A.1    Groblewski, G.E.2    Schäfer, C.3    Guan, K.-L.4    Williams, J.A.5
  • 52
    • 0029864557 scopus 로고    scopus 로고
    • Cholecystokinin stimulates formation of Shc-Grb2 complex in rat pancreatic acinar cells through a protein kinase C-dependent mechanism
    • Dabrowski A, VanderKuur JA, Carter-Su C, Williams JA. Cholecystokinin stimulates formation of Shc-Grb2 complex in rat pancreatic acinar cells through a protein kinase C-dependent mechanism. J Biol Chem 1996;271:27125-9.
    • (1996) J Biol Chem , vol.271 , pp. 27125-27129
    • Dabrowski, A.1    VanderKuur, J.A.2    Carter-Su, C.3    Williams, J.A.4
  • 53
    • 0030029422 scopus 로고    scopus 로고
    • Gastrin induces tyrosine phosphorylation of Shc proteins and their association with the Grb2/Sos complex
    • Seva C, Kowalski-Chauvel A, Blanchet J-S, Vaysse N, Pradayrol L. Gastrin induces tyrosine phosphorylation of Shc proteins and their association with the Grb2/Sos complex. FEBS Lett 1996; 378:74-8.
    • (1996) FEBS Lett , vol.378 , pp. 74-78
    • Seva, C.1    Kowalski-Chauvel, A.2    Blanchet, J.-S.3    Vaysse, N.4    Pradayrol, L.5
  • 54
    • 0033000345 scopus 로고    scopus 로고
    • Carbachol activates ERK2 in isolated gastric parietal cells via multiple signaling pathways
    • Takeuchi Y, Pausawasdi N, Todisco A. Carbachol activates ERK2 in isolated gastric parietal cells via multiple signaling pathways. Am J Physiol 1999;276:G1484-92.
    • (1999) Am J Physiol , vol.276
    • Takeuchi, Y.1    Pausawasdi, N.2    Todisco, A.3
  • 56
    • 0030747173 scopus 로고    scopus 로고
    • Pancreatic acinar cell intracellular signaling mechanisms
    • Williams JA. Pancreatic acinar cell intracellular signaling mechanisms. Curr Opin Gastroenterol 1997;13:369-74.
    • (1997) Curr Opin Gastroenterol , vol.13 , pp. 369-374
    • Williams, J.A.1
  • 57
    • 0030567987 scopus 로고    scopus 로고
    • Stress-activated protein kinase activation is the earliest direct correlate to the induction of secretagogue-induced pancreatitis in rats
    • Grady T, Dabrowski A, Williams JA, Logsdon CD. Stress-activated protein kinase activation is the earliest direct correlate to the induction of secretagogue-induced pancreatitis in rats. Biochem Biophys Res Commun 1996;227:1-7.
    • (1996) Biochem Biophys Res Commun , vol.227 , pp. 1-7
    • Grady, T.1    Dabrowski, A.2    Williams, J.A.3    Logsdon, C.D.4
  • 58
    • 0032893960 scopus 로고    scopus 로고
    • p38 Map kinase is expressed in the pancreas and is immediately activated following cerulein hyperstimulation
    • Wagner ACC, Metzler W, Höfken T, Weber H, Göke B. p38 Map kinase is expressed in the pancreas and is immediately activated following cerulein hyperstimulation. Digestion 1999;60:41-7.
    • (1999) Digestion , vol.60 , pp. 41-47
    • Wagner, A.C.C.1    Metzler, W.2    Höfken, T.3    Weber, H.4    Göke, B.5
  • 59
    • 0029809552 scopus 로고    scopus 로고
    • Hyperthermia induces heat shock protein expression and protection against cerulein-induced pancreatitis in rats
    • Wagner ACC, Weber H, Jonas L, Nizze H, Strowski M, Fiedler F, et al. Hyperthermia induces heat shock protein expression and protection against cerulein-induced pancreatitis in rats. Gastroenterology 1996;111:1333-42.
    • (1996) Gastroenterology , vol.111 , pp. 1333-1342
    • Wagner, A.C.C.1    Weber, H.2    Jonas, L.3    Nizze, H.4    Strowski, M.5    Fiedler, F.6
  • 60
    • 4243606604 scopus 로고    scopus 로고
    • Effects of c-Jun N-terminal kinase (JNK) inhibition on cerulein-induced pancreatitis in rats
    • Wagner ACC, Mazzucchelli L, Miller M, Göke B. Effects of c-Jun N-terminal kinase (JNK) inhibition on cerulein-induced pancreatitis in rats (abstract). Gastroenterology 1999;116:G5091.
    • (1999) Gastroenterology , vol.116
    • Wagner, A.C.C.1    Mazzucchelli, L.2    Miller, M.3    Göke, B.4
  • 61
    • 0028939598 scopus 로고    scopus 로고
    • Supramaximal secretagogue stimulation enhances heat shock protein expression in the rat pancreas
    • Weber CK, Gress T, Müller-Pillasch F, Lerch MM, Weidenbach H, Adler G. Supramaximal secretagogue stimulation enhances heat shock protein expression in the rat pancreas. Pancreas 1997; 10:360-7.
    • (1997) Pancreas , vol.10 , pp. 360-367
    • Weber, C.K.1    Gress, T.2    Müller-Pillasch, F.3    Lerch, M.M.4    Weidenbach, H.5    Adler, G.6
  • 63
    • 8544253977 scopus 로고    scopus 로고
    • Differential induction of hsp60 and hsp72 by different stress situations in rats
    • Otaka M, Okuyama A, Otani S, Jin M, Itoh S, Itoh H, et al. Differential induction of hsp60 and hsp72 by different stress situations in rats. Dig Dis Sci 1997;42:1473-9.
    • (1997) Dig Dis Sci , vol.42 , pp. 1473-1479
    • Otaka, M.1    Okuyama, A.2    Otani, S.3    Jin, M.4    Itoh, S.5    Itoh, H.6
  • 64
    • 0030783523 scopus 로고    scopus 로고
    • Caerulein pancreatitis increases mRNA but reduces protein levels of rat pancreatic heat shock proteins
    • Strowski MZ, Sparmann G, Weber H, Fiedler F, Printz H, Jonas L, et al. Caerulein pancreatitis increases mRNA but reduces protein levels of rat pancreatic heat shock proteins. Am J Physiol 1997;273:G937-45.
    • (1997) Am J Physiol , vol.273
    • Strowski, M.Z.1    Sparmann, G.2    Weber, H.3    Fiedler, F.4    Printz, H.5    Jonas, L.6
  • 66
    • 0033373475 scopus 로고    scopus 로고
    • Hsp27 expression regulates cholecystokinin-induced changes of the actin cytoskeleton in CHO-CCK-A cells
    • December (in press)
    • Schäfer C, Clapp P, Welsh MJ, Benndorf R, Williams JA. Hsp27 expression regulates cholecystokinin-induced changes of the actin cytoskeleton in CHO-CCK-A cells. Am J Physiol: Cell Physiol 1999;277:December (in press).
    • (1999) Am J Physiol: Cell Physiol , vol.277
    • Schäfer, C.1    Clapp, P.2    Welsh, M.J.3    Benndorf, R.4    Williams, J.A.5
  • 67
    • 4244172187 scopus 로고    scopus 로고
    • Acute necrotizing pancreatitis induces heat-shock protein 27 expression and alters the actin cytoskeleton in pancreatic acinar cells
    • Tashiro M, Schäfer C, Ernst SA, Williams JA. Acute necrotizing pancreatitis induces heat-shock protein 27 expression and alters the actin cytoskeleton in pancreatic acinar cells (abstract). Gastroenterology 1999;116:G5063.
    • (1999) Gastroenterology , vol.116
    • Tashiro, M.1    Schäfer, C.2    Ernst, S.A.3    Williams, J.A.4
  • 68
    • 26544438469 scopus 로고    scopus 로고
    • Acute pancreatitis results in induction of heat shock factor-1 and heat shock protein 7C
    • Ethridge RT, Ehlers RA, Ehlers BM. Acute pancreatitis results in induction of heat shock factor-1 and heat shock protein 7C (abstract). Gastroenterology 1999;116:G4863.
    • (1999) Gastroenterology , vol.116
    • Ethridge, R.T.1    Ehlers, R.A.2    Ehlers, B.M.3
  • 69
    • 4243366998 scopus 로고    scopus 로고
    • Induction of heat shock proteins prevents hyperstimulation-induced activation of trypsinogen in an in vitro culture of pancreatic fragments
    • Bhagat L, Hietaranta AJ, Akella U, Singh VP, Norman J, Steer ML, Saluja AK. Induction of heat shock proteins prevents hyperstimulation-induced activation of trypsinogen in an in vitro culture of pancreatic fragments (abstract). Gastroenterology 1999;116:G4823.
    • (1999) Gastroenterology , vol.116
    • Bhagat, L.1    Hietaranta, A.J.2    Akella, U.3    Singh, V.P.4    Norman, J.5    Steer, M.L.6    Saluja, A.K.7
  • 71
    • 0033613683 scopus 로고    scopus 로고
    • Molecular chaperones and the heat shock response
    • Kaufman RJ. Molecular chaperones and the heat shock response. Biochem Biophys Acta 1998;1423:R13-27.
    • (1998) Biochem Biophys Acta , vol.1423
    • Kaufman, R.J.1
  • 72
    • 0032406050 scopus 로고    scopus 로고
    • Stress proteins and apoptosis in prenatal development, cancer and medicine
    • Anderson RL. Stress proteins and apoptosis in prenatal development, cancer and medicine. Cell Stress Chaperones 1998;3:209-12.
    • (1998) Cell Stress Chaperones , vol.3 , pp. 209-212
    • Anderson, R.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.