Lysosomal protease pathways to apoptosis: Cleavage of Bid, not pro-caspases, is the most likely route

Journal of Biological Chemistry

Volumn 276, Issue 5, 2001, Pages 3149-3157

  Stoka, Veronika ^a,b   Turk, Boris ^b   Schendel, Sharon L ^a   Kim, Tae Hyoung ^c   Cirman, Tina ^b   Snipas, Scott J ^a   Ellerby, Lisa M ^d   Bredesen, Dale ^d   Freeze, Hudson ^a   Abrahamson, Magnus ^e   Brömme, Dieter ^f   Krajewski, Stanislaw ^a   Reed, John C ^a   Yin, Xiao Ming ^c   Turk, Vito ^b   Salvesen, Guy S ^a  

^a BURNHAM INSTITUTE   (United States)

^b JO EF STEFAN INSTITUTE   (Slovenia)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^e LUND UNIVERSITY HOSPITAL   (Sweden)

^f MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL ACTIVATION; CHEMICAL BONDS; CYTOLOGY; ENZYME KINETICS; GENES; NEUROLOGY; REACTION KINETICS;

APOPTOSIS; MITOCHONDRIA;

ENZYMES;

BIOCHEMICAL MARKER; CATHEPSIN B; CATHEPSIN L; CRUZIPAIN; CYTOCHROME C; ENZYME PRECURSOR; LYSOSOME ENZYME; PROTEINASE; RECOMBINANT PROTEIN; BID PROTEIN, HUMAN; BID PROTEIN, MOUSE; BID PROTEIN, RAT; CARRIER PROTEIN; CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, MOUSE; CASP3 PROTEIN, RAT; CASP7 PROTEIN, HUMAN; CASP7 PROTEIN, MOUSE; CASPASE; CASPASE 3; CASPASE 7; PROTEIN BID;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; ENZYME ACTIVITY; ENZYME RELEASE; LYSOSOME; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA CRUZI; ANIMAL; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOSOL; ENZYMOLOGY; HUMAN; METABOLISM; PHYSIOLOGY; RAT;

ANIMALIA; MAMMALIA; PROTOZOA; TRYPANOSOMA; TRYPANOSOMA CRUZI;

ANIMALS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CASPASE 3; CASPASE 7; CASPASES; CYTOSOL; ENDOPEPTIDASES; HUMANS; LYSOSOMES; MICE; MODELS, MOLECULAR; RATS; TUMOR CELLS, CULTURED;

EID: 0035793580     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008944200     Document Type: Article

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