Adenovirus-mediated transfer of p53 and p16INK4a results in pancreatic cancer regression in vitro and in vivo

Gene Therapy

Volumn 8, Issue 3, 2001, Pages 199-208

  Ghaneh, P ^a   Greenhalf, W ^a   Humphreys, M ^a   Wilson, D ^b   Zumstein, L ^b   Lemoine, N R ^c   Neoptolemos, J P ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b Introgen Therapeutics Inc   (United States)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Gene therapy; P16INK4a; P53; Pancreatic cancer; Tumour suppressor gene

Indexed keywords

BETA GALACTOSIDASE; LUCIFERASE; PROTEIN P16; PROTEIN P53; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER REGRESSION; CELL CYCLE G1 PHASE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MOUSE STRAIN; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; SUBCUTANEOUS TISSUE; TUMOR VOLUME; VIRUS INFECTION; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; CELL DIVISION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, P16; GENES, P53; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSGENES; TUMOR CELLS, CULTURED;

ADENOVIRIDAE; ANIMALIA;

EID: 0035114253     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301394     Document Type: Article

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