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Volumn 94, Issue 3, 1998, Pages 345-355

Peroxynitrite-induced thymocyte apoptosis: The role of caspases and poly (ADP-ribose) synthetase (PARS) activation

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; SYNTHETASE; T LYMPHOCYTE RECEPTOR;

EID: 0031822063     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1998.00534.x     Document Type: Article
Times cited : (192)

References (51)
  • 3
    • 0029967353 scopus 로고    scopus 로고
    • Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes
    • ANDERSON K.L., ANDERSON G., MICHELL R.H., JENKINSON E.J. & OWEN J.J. (1996) Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes. J Immunol 156, 4083.
    • (1996) J Immunol , vol.156 , pp. 4083
    • Anderson, K.L.1    Anderson, G.2    Michell, R.H.3    Jenkinson, E.J.4    Owen, J.J.5
  • 4
    • 0027957577 scopus 로고
    • + thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28
    • + thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28. J Exp Med 179, 709.
    • (1994) J Exp Med , vol.179 , pp. 709
    • Punt, J.A.1    Osborne, B.A.2    Takahama, Y.3    Sharrow, S.O.4    Singer, A.5
  • 5
    • 0027490727 scopus 로고
    • + thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr
    • + thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr. Proc Natl Acad Sci 90, 10 340.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 10340
    • Drappa, J.1    Brot, N.2    Elkon, K.B.3
  • 6
    • 0027957777 scopus 로고
    • Thy-1 triggers mouse thymocyte apoptosis through a bcl-2 resistant mechanism
    • HUEBER A.O., RAPOSO G., PIERRES M. & HE H.T. (1994) Thy-1 triggers mouse thymocyte apoptosis through a bcl-2 resistant mechanism. J Exp Med 179, 785.
    • (1994) J Exp Med , vol.179 , pp. 785
    • Hueber, A.O.1    Raposo, G.2    Pierres, M.3    He, H.T.4
  • 7
    • 0029907408 scopus 로고    scopus 로고
    • Cross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death
    • LERNER A., CLAYTON L.K., MIZOGUCHI E. et al. (1996) Cross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death. EMBO J 15, 5876.
    • (1996) EMBO J , vol.15 , pp. 5876
    • Lerner, A.1    Clayton, L.K.2    Mizoguchi, E.3
  • 8
    • 0030565418 scopus 로고    scopus 로고
    • Reactive oxygen intermediate (s) (ROI ): Common mediator (s) of poly (ADP-ribose) cleavage and apoptosis
    • MCGOWAN A.J., RUIZ-RUIZ M.C., GORMAN A.M., LOPEZ-RIVAS A. & COTTER T.G. (1996) Reactive oxygen intermediate (s) (ROI ): Common mediator (s) of poly (ADP-ribose) cleavage and apoptosis. FEBS Lett 392, 299.
    • (1996) FEBS Lett , vol.392 , pp. 299
    • Mcgowan, A.J.1    Ruiz-Ruiz, M.C.2    Gorman, A.M.3    Lopez-Rivas, A.4    Cotter, T.G.5
  • 10
    • 0031569964 scopus 로고    scopus 로고
    • Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes
    • TAI X.G., TOYO-OKA K., YAMAMOTO N. et al. (1997) Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes. J Immunol 158, 4696.
    • (1997) J Immunol , vol.158 , pp. 4696
    • Tai, X.G.1    Toyo-Oka, K.2    Yamamoto, N.3
  • 11
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad and the ugly
    • BECKMAN J.S. & KOPPENOL W.H. (1996) Nitric oxide, superoxide, and peroxynitrite: the good, the bad and the ugly. Am J Physiol 271, 1424.
    • (1996) Am J Physiol , vol.271 , pp. 1424
    • Beckman, J.S.1    Koppenol, W.H.2
  • 12
    • 0030203367 scopus 로고    scopus 로고
    • The role of peroxynitrite in the pathophysiology of shock, inflammation and ischemia-reperfusion injury
    • SZABÓ C. (1996) The role of peroxynitrite in the pathophysiology of shock, inflammation and ischemia-reperfusion injury. Shock 6, 79.
    • (1996) Shock , vol.6 , pp. 79
    • Szabó, C.1
  • 14
    • 0030854951 scopus 로고    scopus 로고
    • Endothelial dysfunction in endotoxic shock: Importance of the activation of poly (ADP ribose) synthetase (PARS) by peroxynitrite
    • SZABÓ C., CUZZOCREA S., ZINGARELLI B., O'CONNOR M. & SALZMAN A.L. (1997) Endothelial dysfunction in endotoxic shock: importance of the activation of poly (ADP ribose) synthetase (PARS) by peroxynitrite. J Clin Invest 100, 723.
    • (1997) J Clin Invest , vol.100 , pp. 723
    • Szabó, C.1    Cuzzocrea, S.2    Zingarelli, B.3    O'Connor, M.4    Salzman, A.L.5
  • 16
    • 0029959717 scopus 로고    scopus 로고
    • DNA strand breakage and activation of poly-ADP ribosyltransferase: A cytotoxic pathway triggered by peroxynitrite
    • SZABÓ C. (1996) DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite. Free Rad Biol Med 21, 855.
    • (1996) Free Rad Biol Med , vol.21 , pp. 855
    • Szabó, C.1
  • 17
    • 0030000690 scopus 로고    scopus 로고
    • DNA strand breakage, activation of poly-ADP ribosyl synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite
    • SZABÓ C., ZINGARELLI B., O'CONNOR M. & SALZMAN A.L. (1996) DNA strand breakage, activation of poly-ADP ribosyl synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite. Proc Natl Acad Sci USA 93, 1753.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1753
    • Szabó, C.1    Zingarelli, B.2    O'Connor, M.3    Salzman, A.L.4
  • 18
    • 0030026515 scopus 로고    scopus 로고
    • Peroxynitrite-mediated DNA strand breakage activates poly-ADP ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide
    • ZINGARELLI B., O'CONNOR M., WONG H., SALZMAN A.L. & SZABÓ C. (1996) Peroxynitrite-mediated DNA strand breakage activates poly-ADP ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. J Immunol 156, 350.
    • (1996) J Immunol , vol.156 , pp. 350
    • Zingarelli, B.1    O'Connor, M.2    Wong, H.3    Salzman, A.L.4    Szabó, C.5
  • 19
    • 0026032580 scopus 로고
    • Mechanisms of oxidant injury of cells
    • COCHRANE C. (1991) Mechanisms of oxidant injury of cells. Mol Aspects Med 12, 137.
    • (1991) Mol Aspects Med , vol.12 , pp. 137
    • Cochrane, C.1
  • 20
    • 0029068871 scopus 로고
    • Identification and inhibition of the ICE/CED-3 protease necessery for mammalian apoptosis
    • NICHOLSON D.W., ALI A., THORNBERRY N.A. et al. (1995) Identification and inhibition of the ICE/CED-3 protease necessery for mammalian apoptosis. Nature 376, 37.
    • (1995) Nature , vol.376 , pp. 37
    • Nicholson, D.W.1    Ali, A.2    Thornberry, N.A.3
  • 21
    • 0028990125 scopus 로고
    • Yama/CPP. 32β, a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase
    • TEWARI M., QUAN L.T., O'ROURKE K. et al. (1995) Yama/CPP. 32β, a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell 81, 801.
    • (1995) Cell , vol.81 , pp. 801
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3
  • 22
    • 0024470862 scopus 로고
    • Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
    • KAUFMANN S.H. (1989) Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res 49, 5870.
    • (1989) Cancer Res , vol.49 , pp. 5870
    • Kaufmann, S.H.1
  • 23
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly (ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
    • KAUFMANN S.H., DESNOYERS S., OTTAVIANO Y., DAVIDSON N.E. & POIRIER G.G. (1993) Specific proteolytic cleavage of poly (ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res 53, 3976.
    • (1993) Cancer Res , vol.53 , pp. 3976
    • Kaufmann, S.H.1    Desnoyers, S.2    Ottaviano, Y.3    Davidson, N.E.4    Poirier, G.G.5
  • 24
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homologue of the C. elegams cell death gene ced-3
    • MIURA M., ZHU H., ROTELLO R., HARTWIEG E.A. & YUAN J. (1993) Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homologue of the C. elegams cell death gene ced-3. Cell 75, 653.
    • (1993) Cell , vol.75 , pp. 653
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hartwieg, E.A.4    Yuan, J.5
  • 25
    • 0030814675 scopus 로고    scopus 로고
    • Caspases: Killer proteases
    • NICHOLSON D.W. & THORNBERRY N.A. (1997) Caspases: killer proteases. TIBS 22, 299.
    • (1997) TIBS , vol.22 , pp. 299
    • Nicholson, D.W.1    Thornberry, N.A.2
  • 26
    • 0030969193 scopus 로고    scopus 로고
    • The apoptotic cysteine protease CPP. 32
    • KUMAR S. (1997) The apoptotic cysteine protease CPP. 32. Int J Biochem Cell Biol 29, 393.
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 393
    • Kumar, S.1
  • 27
    • 0029919404 scopus 로고    scopus 로고
    • Role of ICE-proteasees in apoptosis
    • DIXIT V.M. (1996) Role of ICE-proteasees in apoptosis. Adv Exp Med Biol 406, 113.
    • (1996) Adv Exp Med Biol , vol.406 , pp. 113
    • Dixit, V.M.1
  • 28
    • 0021099832 scopus 로고
    • 2+-dependent/poly (ADP-ribose) -sensitive endonuclease
    • 2+-dependent/poly (ADP-ribose) -sensitive endonuclease. J Biol Chem 258, 9184.
    • (1983) J Biol Chem , vol.258 , pp. 9184
    • Tanigawa, Y.1    Shimoyama, M.2
  • 30
    • 0030984490 scopus 로고    scopus 로고
    • PARP is important for genomic stability but dispensable in apoptosis
    • WANG Z.-Q., STINGL L., MORRISON C., JANTSCH M. et al. (1997) PARP is important for genomic stability but dispensable in apoptosis. Genes Dev 11, 2347.
    • (1997) Genes Dev , vol.11 , pp. 2347
    • Wang, Z.-Q.1    Stingl, L.2    Morrison, C.3    Jantsch, M.4
  • 31
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
    • VERMES I., HAANEN C. & STEFFENS-NAKKEN H. & REUTELINGSPERGER C. (1995) A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 184, 39.
    • (1995) J Immunol Methods , vol.184 , pp. 39
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 32
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • MARTIN S.J., REUTELINGSPERGER C.P.M., MCGAHON A.J., RADER J.A., VAN SCHIE R.C.A.A., LAFACE D.M. & GREEN D.R. (1995) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. J Exp Med 182, 1545.
    • (1995) J Exp Med , vol.182 , pp. 1545
    • Martin, S.J.1    Reutelingsperger, C.P.M.2    Mcgahon, A.J.3    Rader, J.A.4    Van Schie, R.C.A.A.5    Laface, D.M.6    Green, D.R.7
  • 33
    • 0029185707 scopus 로고
    • 2+ associated with apoptosis
    • 2+ associated with apoptosis. Methods Cell Biol 46, 41.
    • (1995) Methods Cell Biol , vol.46 , pp. 41
    • Eastman, A.1
  • 34
    • 0030904925 scopus 로고    scopus 로고
    • Selective activation of caspases during apoptotic induction in IIL-60 cells. Effects of a tetrapeptide inhibitor
    • POLVERINO A.J. & PATTERSON S.D. (1997) Selective activation of caspases during apoptotic induction in IIL-60 cells. Effects of a tetrapeptide inhibitor. J Biol Chem 272, 7013.
    • (1997) J Biol Chem , vol.272 , pp. 7013
    • Polverino, A.J.1    Patterson, S.D.2
  • 35
    • 10544238107 scopus 로고    scopus 로고
    • Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis
    • VANAGS D.M., PÖRN-ARES M., COPPOLA S., BURGESS D.H. & ORENIUS S. (1997) Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis. J Biol Chem 271, 31 075.
    • (1997) J Biol Chem , vol.271 , pp. 31075
    • Vanags, D.M.1    Pörn-Ares, M.2    Coppola, S.3    Burgess, D.H.4    Orenius, S.5
  • 36
    • 0029153913 scopus 로고
    • Apoptosis and necrosis: Two distinct event induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
    • BONFOCO E., KRAINC D., ANKARCRONA M., NICOTERA P. & LIPTON S.A. (1995) Apoptosis and necrosis: Two distinct event induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci 92, 7162.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 7162
    • Bonfoco, E.1    Krainc, D.2    Ankarcrona, M.3    Nicotera, P.4    Lipton, S.A.5
  • 37
    • 0028841484 scopus 로고
    • Different basal NAD levels determine opposite effects of poly (ADP-ribosyl) polymerase inhibitors on H2O2-induced apoptosis
    • COPPOLA S., NOSSERI C., MARESCA V. & GHIBELLI L. (1995) Different basal NAD levels determine opposite effects of poly (ADP-ribosyl) polymerase inhibitors on H2O2-induced apoptosis. Exp Cell Res 221, 462.
    • (1995) Exp Cell Res , vol.221 , pp. 462
    • Coppola, S.1    Nosseri, C.2    Maresca, V.3    Ghibelli, L.4
  • 38
    • 0030900980 scopus 로고    scopus 로고
    • Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
    • LEIST M., SINGLE B., CASTOLDI A.F., KUHNLE S. & NICOTERA P. (1997) Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J Exp Med 185, 1481.
    • (1997) J Exp Med , vol.185 , pp. 1481
    • Leist, M.1    Single, B.2    Castoldi, A.F.3    Kuhnle, S.4    Nicotera, P.5
  • 40
    • 0030798072 scopus 로고    scopus 로고
    • Role of caspases (ICE/CED 3) proteases in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A
    • KAUSHAL G.P., UEDA N. & SHAH S.V. (1997) Role of caspases (ICE/CED 3) proteases in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A. Kidney Int 52, 438.
    • (1997) Kidney Int , vol.52 , pp. 438
    • Kaushal, G.P.1    Ueda, N.2    Shah, S.V.3
  • 41
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • YANG J., LIU X., BHALLA K., KIM C.N. et al. (1997) Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Sci 275, 1129.
    • (1997) Sci , vol.275 , pp. 1129
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4
  • 42
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for bcl-2 regulation of apoptosis
    • KLUCK R.M., BOSSY-WETZEL E., GREEN D.R. & NEWMEYER D.D. (1997) The release of cytochrome c from mitochondria: a primary site for bcl-2 regulation of apoptosis. Sci 275, 1132.
    • (1997) Sci , vol.275 , pp. 1132
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 43
    • 0029058055 scopus 로고
    • Apoptosis: Lessons from in vitro systems
    • EARNSHAW W.C. (1995) Apoptosis: Lessons from in vitro systems. Trends Cell Biol 5, 217.
    • (1995) Trends Cell Biol , vol.5 , pp. 217
    • Earnshaw, W.C.1
  • 44
    • 0040984333 scopus 로고    scopus 로고
    • Requirement of poly (ADP-ribose) polymerase in recovery from DNA damage in mice and in cells
    • DE MURCIA J.M., NIEDERGANG C., TRUCCO C. et al. (1997) Requirement of poly (ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci USA 94, 7303.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 7303
    • De Murcia, J.M.1    Niedergang, C.2    Trucco, C.3
  • 45
    • 0030611436 scopus 로고    scopus 로고
    • 6-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide
    • 6-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide. Mol Pharmacol 52, 249.
    • (1997) Mol Pharmacol , vol.52 , pp. 249
    • Tentori, L.1    Orlando, L.2    Lacal, P.M.3
  • 47
    • 0030992125 scopus 로고    scopus 로고
    • Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, and inhibitor of poly (ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways
    • SZABÓ C., WONG H.R., BAUER P.I. et al. (1997) Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, and inhibitor of poly (ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways. Int J Oncol 10, 1093.
    • (1997) Int J Oncol , vol.10 , pp. 1093
    • Szabó, C.1    Wong, H.R.2    Bauer, P.I.3
  • 48
    • 0030870278 scopus 로고    scopus 로고
    • Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects
    • SZABÓ C., LIM L.H.K., CUZZOCREA S. et al. (1997) Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. J Exp Med 186, 1041.
    • (1997) J Exp Med , vol.186 , pp. 1041
    • Szabó, C.1    Lim, L.H.K.2    Cuzzocrea, S.3
  • 49
    • 0030788898 scopus 로고    scopus 로고
    • Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion
    • CUZZOCREA S., ZINGARELLI B., COSTANTINO G. et al. (1997) Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion. Br J Pharmacol 121, 1065.
    • (1997) Br J Pharmacol , vol.121 , pp. 1065
    • Cuzzocrea, S.1    Zingarelli, B.2    Costantino, G.3
  • 50
    • 0030842946 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischaemia
    • ELIASSON M.J.L., SAMPEI K., MANDIR A.S. et al. (1997) Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischaemia. Nature Med 3, 1089.
    • (1997) Nature Med , vol.3 , pp. 1089
    • Eliasson, M.J.L.1    Sampei, K.2    Mandir, A.S.3
  • 51
    • 0032127666 scopus 로고    scopus 로고
    • Role of poly(ADP-ribose) synthetasc activation in inflammation and reperfusion injury
    • in press
    • SZABÓ C. & DAWSON V.L (1998) Role of poly(ADP-ribose) synthetasc activation in inflammation and reperfusion injury. Trends Pharmacol Sci, in press.
    • (1998) Trends Pharmacol Sci
    • Szabó, C.1    Dawson, V.L.2


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