-
3
-
-
0029967353
-
Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes
-
ANDERSON K.L., ANDERSON G., MICHELL R.H., JENKINSON E.J. & OWEN J.J. (1996) Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes. J Immunol 156, 4083.
-
(1996)
J Immunol
, vol.156
, pp. 4083
-
-
Anderson, K.L.1
Anderson, G.2
Michell, R.H.3
Jenkinson, E.J.4
Owen, J.J.5
-
5
-
-
0027490727
-
+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr
-
+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr. Proc Natl Acad Sci 90, 10 340.
-
(1993)
Proc Natl Acad Sci
, vol.90
, pp. 10340
-
-
Drappa, J.1
Brot, N.2
Elkon, K.B.3
-
6
-
-
0027957777
-
Thy-1 triggers mouse thymocyte apoptosis through a bcl-2 resistant mechanism
-
HUEBER A.O., RAPOSO G., PIERRES M. & HE H.T. (1994) Thy-1 triggers mouse thymocyte apoptosis through a bcl-2 resistant mechanism. J Exp Med 179, 785.
-
(1994)
J Exp Med
, vol.179
, pp. 785
-
-
Hueber, A.O.1
Raposo, G.2
Pierres, M.3
He, H.T.4
-
7
-
-
0029907408
-
Cross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death
-
LERNER A., CLAYTON L.K., MIZOGUCHI E. et al. (1996) Cross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death. EMBO J 15, 5876.
-
(1996)
EMBO J
, vol.15
, pp. 5876
-
-
Lerner, A.1
Clayton, L.K.2
Mizoguchi, E.3
-
8
-
-
0030565418
-
Reactive oxygen intermediate (s) (ROI ): Common mediator (s) of poly (ADP-ribose) cleavage and apoptosis
-
MCGOWAN A.J., RUIZ-RUIZ M.C., GORMAN A.M., LOPEZ-RIVAS A. & COTTER T.G. (1996) Reactive oxygen intermediate (s) (ROI ): Common mediator (s) of poly (ADP-ribose) cleavage and apoptosis. FEBS Lett 392, 299.
-
(1996)
FEBS Lett
, vol.392
, pp. 299
-
-
Mcgowan, A.J.1
Ruiz-Ruiz, M.C.2
Gorman, A.M.3
Lopez-Rivas, A.4
Cotter, T.G.5
-
9
-
-
0029052841
-
Nitric oxide induces apoptosis in mouse thymocytes
-
FEHSEL K., KRÖNCKE, K.-D., MEYER K.L., HUBER H., WAHN V. & KOLB-BACHOFEN V. (1995) Nitric oxide induces apoptosis in mouse thymocytes. J Immunol 155, 2858.
-
(1995)
J Immunol
, vol.155
, pp. 2858
-
-
Fehsel, K.1
Kröncke, K.-D.2
Meyer, K.L.3
Huber, H.4
Wahn, V.5
Kolb-Bachofen, V.6
-
10
-
-
0031569964
-
Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes
-
TAI X.G., TOYO-OKA K., YAMAMOTO N. et al. (1997) Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes. J Immunol 158, 4696.
-
(1997)
J Immunol
, vol.158
, pp. 4696
-
-
Tai, X.G.1
Toyo-Oka, K.2
Yamamoto, N.3
-
11
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: The good, the bad and the ugly
-
BECKMAN J.S. & KOPPENOL W.H. (1996) Nitric oxide, superoxide, and peroxynitrite: the good, the bad and the ugly. Am J Physiol 271, 1424.
-
(1996)
Am J Physiol
, vol.271
, pp. 1424
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
12
-
-
0030203367
-
The role of peroxynitrite in the pathophysiology of shock, inflammation and ischemia-reperfusion injury
-
SZABÓ C. (1996) The role of peroxynitrite in the pathophysiology of shock, inflammation and ischemia-reperfusion injury. Shock 6, 79.
-
(1996)
Shock
, vol.6
, pp. 79
-
-
Szabó, C.1
-
13
-
-
0029014788
-
Peroxynitrite-induced apoptosis in HL-60 cells
-
LIN K.-T., XUE J.-Y., NOMEN M., SPUR B. & WONG P.Y.-K. (1995) Peroxynitrite-induced apoptosis in HL-60 cells. J Biol Chem 270, 16 487.
-
(1995)
J Biol Chem
, vol.270
, pp. 16487
-
-
Lin, K.-T.1
Xue, J.-Y.2
Nomen, M.3
Spur, B.4
Wong, P.Y.-K.5
-
14
-
-
0030854951
-
Endothelial dysfunction in endotoxic shock: Importance of the activation of poly (ADP ribose) synthetase (PARS) by peroxynitrite
-
SZABÓ C., CUZZOCREA S., ZINGARELLI B., O'CONNOR M. & SALZMAN A.L. (1997) Endothelial dysfunction in endotoxic shock: importance of the activation of poly (ADP ribose) synthetase (PARS) by peroxynitrite. J Clin Invest 100, 723.
-
(1997)
J Clin Invest
, vol.100
, pp. 723
-
-
Szabó, C.1
Cuzzocrea, S.2
Zingarelli, B.3
O'Connor, M.4
Salzman, A.L.5
-
16
-
-
0029959717
-
DNA strand breakage and activation of poly-ADP ribosyltransferase: A cytotoxic pathway triggered by peroxynitrite
-
SZABÓ C. (1996) DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite. Free Rad Biol Med 21, 855.
-
(1996)
Free Rad Biol Med
, vol.21
, pp. 855
-
-
Szabó, C.1
-
17
-
-
0030000690
-
DNA strand breakage, activation of poly-ADP ribosyl synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite
-
SZABÓ C., ZINGARELLI B., O'CONNOR M. & SALZMAN A.L. (1996) DNA strand breakage, activation of poly-ADP ribosyl synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite. Proc Natl Acad Sci USA 93, 1753.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1753
-
-
Szabó, C.1
Zingarelli, B.2
O'Connor, M.3
Salzman, A.L.4
-
18
-
-
0030026515
-
Peroxynitrite-mediated DNA strand breakage activates poly-ADP ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide
-
ZINGARELLI B., O'CONNOR M., WONG H., SALZMAN A.L. & SZABÓ C. (1996) Peroxynitrite-mediated DNA strand breakage activates poly-ADP ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. J Immunol 156, 350.
-
(1996)
J Immunol
, vol.156
, pp. 350
-
-
Zingarelli, B.1
O'Connor, M.2
Wong, H.3
Salzman, A.L.4
Szabó, C.5
-
19
-
-
0026032580
-
Mechanisms of oxidant injury of cells
-
COCHRANE C. (1991) Mechanisms of oxidant injury of cells. Mol Aspects Med 12, 137.
-
(1991)
Mol Aspects Med
, vol.12
, pp. 137
-
-
Cochrane, C.1
-
20
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessery for mammalian apoptosis
-
NICHOLSON D.W., ALI A., THORNBERRY N.A. et al. (1995) Identification and inhibition of the ICE/CED-3 protease necessery for mammalian apoptosis. Nature 376, 37.
-
(1995)
Nature
, vol.376
, pp. 37
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
-
21
-
-
0028990125
-
Yama/CPP. 32β, a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase
-
TEWARI M., QUAN L.T., O'ROURKE K. et al. (1995) Yama/CPP. 32β, a mammalian homolog of CED-3, is a crmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell 81, 801.
-
(1995)
Cell
, vol.81
, pp. 801
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
-
22
-
-
0024470862
-
Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
-
KAUFMANN S.H. (1989) Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res 49, 5870.
-
(1989)
Cancer Res
, vol.49
, pp. 5870
-
-
Kaufmann, S.H.1
-
23
-
-
0027255417
-
Specific proteolytic cleavage of poly (ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
-
KAUFMANN S.H., DESNOYERS S., OTTAVIANO Y., DAVIDSON N.E. & POIRIER G.G. (1993) Specific proteolytic cleavage of poly (ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res 53, 3976.
-
(1993)
Cancer Res
, vol.53
, pp. 3976
-
-
Kaufmann, S.H.1
Desnoyers, S.2
Ottaviano, Y.3
Davidson, N.E.4
Poirier, G.G.5
-
24
-
-
0027449187
-
Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homologue of the C. elegams cell death gene ced-3
-
MIURA M., ZHU H., ROTELLO R., HARTWIEG E.A. & YUAN J. (1993) Induction of apoptosis in fibroblasts by IL-1β-converting enzyme, a mammalian homologue of the C. elegams cell death gene ced-3. Cell 75, 653.
-
(1993)
Cell
, vol.75
, pp. 653
-
-
Miura, M.1
Zhu, H.2
Rotello, R.3
Hartwieg, E.A.4
Yuan, J.5
-
25
-
-
0030814675
-
Caspases: Killer proteases
-
NICHOLSON D.W. & THORNBERRY N.A. (1997) Caspases: killer proteases. TIBS 22, 299.
-
(1997)
TIBS
, vol.22
, pp. 299
-
-
Nicholson, D.W.1
Thornberry, N.A.2
-
26
-
-
0030969193
-
The apoptotic cysteine protease CPP. 32
-
KUMAR S. (1997) The apoptotic cysteine protease CPP. 32. Int J Biochem Cell Biol 29, 393.
-
(1997)
Int J Biochem Cell Biol
, vol.29
, pp. 393
-
-
Kumar, S.1
-
27
-
-
0029919404
-
Role of ICE-proteasees in apoptosis
-
DIXIT V.M. (1996) Role of ICE-proteasees in apoptosis. Adv Exp Med Biol 406, 113.
-
(1996)
Adv Exp Med Biol
, vol.406
, pp. 113
-
-
Dixit, V.M.1
-
28
-
-
0021099832
-
2+-dependent/poly (ADP-ribose) -sensitive endonuclease
-
2+-dependent/poly (ADP-ribose) -sensitive endonuclease. J Biol Chem 258, 9184.
-
(1983)
J Biol Chem
, vol.258
, pp. 9184
-
-
Tanigawa, Y.1
Shimoyama, M.2
-
29
-
-
0031575931
-
Apoptosis in the absence of poly-(ADP-ribose) polymerase
-
LEIST M., SINGLE B., KÜNSTLE G., VOLBRACHT C., HENTZE H. & NICOTERA P. (1997) Apoptosis in the absence of poly-(ADP-ribose) polymerase. Biochem Biophys Res Commun 233, 518.
-
(1997)
Biochem Biophys Res Commun
, vol.233
, pp. 518
-
-
Leist, M.1
Single, B.2
Künstle, G.3
Volbracht, C.4
Hentze, H.5
Nicotera, P.6
-
30
-
-
0030984490
-
PARP is important for genomic stability but dispensable in apoptosis
-
WANG Z.-Q., STINGL L., MORRISON C., JANTSCH M. et al. (1997) PARP is important for genomic stability but dispensable in apoptosis. Genes Dev 11, 2347.
-
(1997)
Genes Dev
, vol.11
, pp. 2347
-
-
Wang, Z.-Q.1
Stingl, L.2
Morrison, C.3
Jantsch, M.4
-
31
-
-
0029043888
-
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
-
VERMES I., HAANEN C. & STEFFENS-NAKKEN H. & REUTELINGSPERGER C. (1995) A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 184, 39.
-
(1995)
J Immunol Methods
, vol.184
, pp. 39
-
-
Vermes, I.1
Haanen, C.2
Steffens-Nakken, H.3
Reutelingsperger, C.4
-
32
-
-
0028800947
-
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
-
MARTIN S.J., REUTELINGSPERGER C.P.M., MCGAHON A.J., RADER J.A., VAN SCHIE R.C.A.A., LAFACE D.M. & GREEN D.R. (1995) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. J Exp Med 182, 1545.
-
(1995)
J Exp Med
, vol.182
, pp. 1545
-
-
Martin, S.J.1
Reutelingsperger, C.P.M.2
Mcgahon, A.J.3
Rader, J.A.4
Van Schie, R.C.A.A.5
Laface, D.M.6
Green, D.R.7
-
33
-
-
0029185707
-
2+ associated with apoptosis
-
2+ associated with apoptosis. Methods Cell Biol 46, 41.
-
(1995)
Methods Cell Biol
, vol.46
, pp. 41
-
-
Eastman, A.1
-
34
-
-
0030904925
-
Selective activation of caspases during apoptotic induction in IIL-60 cells. Effects of a tetrapeptide inhibitor
-
POLVERINO A.J. & PATTERSON S.D. (1997) Selective activation of caspases during apoptotic induction in IIL-60 cells. Effects of a tetrapeptide inhibitor. J Biol Chem 272, 7013.
-
(1997)
J Biol Chem
, vol.272
, pp. 7013
-
-
Polverino, A.J.1
Patterson, S.D.2
-
35
-
-
10544238107
-
Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis
-
VANAGS D.M., PÖRN-ARES M., COPPOLA S., BURGESS D.H. & ORENIUS S. (1997) Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis. J Biol Chem 271, 31 075.
-
(1997)
J Biol Chem
, vol.271
, pp. 31075
-
-
Vanags, D.M.1
Pörn-Ares, M.2
Coppola, S.3
Burgess, D.H.4
Orenius, S.5
-
36
-
-
0029153913
-
Apoptosis and necrosis: Two distinct event induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
-
BONFOCO E., KRAINC D., ANKARCRONA M., NICOTERA P. & LIPTON S.A. (1995) Apoptosis and necrosis: Two distinct event induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci 92, 7162.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 7162
-
-
Bonfoco, E.1
Krainc, D.2
Ankarcrona, M.3
Nicotera, P.4
Lipton, S.A.5
-
37
-
-
0028841484
-
Different basal NAD levels determine opposite effects of poly (ADP-ribosyl) polymerase inhibitors on H2O2-induced apoptosis
-
COPPOLA S., NOSSERI C., MARESCA V. & GHIBELLI L. (1995) Different basal NAD levels determine opposite effects of poly (ADP-ribosyl) polymerase inhibitors on H2O2-induced apoptosis. Exp Cell Res 221, 462.
-
(1995)
Exp Cell Res
, vol.221
, pp. 462
-
-
Coppola, S.1
Nosseri, C.2
Maresca, V.3
Ghibelli, L.4
-
38
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
-
LEIST M., SINGLE B., CASTOLDI A.F., KUHNLE S. & NICOTERA P. (1997) Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J Exp Med 185, 1481.
-
(1997)
J Exp Med
, vol.185
, pp. 1481
-
-
Leist, M.1
Single, B.2
Castoldi, A.F.3
Kuhnle, S.4
Nicotera, P.5
-
40
-
-
0030798072
-
Role of caspases (ICE/CED 3) proteases in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A
-
KAUSHAL G.P., UEDA N. & SHAH S.V. (1997) Role of caspases (ICE/CED 3) proteases in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A. Kidney Int 52, 438.
-
(1997)
Kidney Int
, vol.52
, pp. 438
-
-
Kaushal, G.P.1
Ueda, N.2
Shah, S.V.3
-
41
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
YANG J., LIU X., BHALLA K., KIM C.N. et al. (1997) Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Sci 275, 1129.
-
(1997)
Sci
, vol.275
, pp. 1129
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
-
42
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for bcl-2 regulation of apoptosis
-
KLUCK R.M., BOSSY-WETZEL E., GREEN D.R. & NEWMEYER D.D. (1997) The release of cytochrome c from mitochondria: a primary site for bcl-2 regulation of apoptosis. Sci 275, 1132.
-
(1997)
Sci
, vol.275
, pp. 1132
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
43
-
-
0029058055
-
Apoptosis: Lessons from in vitro systems
-
EARNSHAW W.C. (1995) Apoptosis: Lessons from in vitro systems. Trends Cell Biol 5, 217.
-
(1995)
Trends Cell Biol
, vol.5
, pp. 217
-
-
Earnshaw, W.C.1
-
44
-
-
0040984333
-
Requirement of poly (ADP-ribose) polymerase in recovery from DNA damage in mice and in cells
-
DE MURCIA J.M., NIEDERGANG C., TRUCCO C. et al. (1997) Requirement of poly (ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci USA 94, 7303.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7303
-
-
De Murcia, J.M.1
Niedergang, C.2
Trucco, C.3
-
45
-
-
0030611436
-
6-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide
-
6-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomide. Mol Pharmacol 52, 249.
-
(1997)
Mol Pharmacol
, vol.52
, pp. 249
-
-
Tentori, L.1
Orlando, L.2
Lacal, P.M.3
-
47
-
-
0030992125
-
Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, and inhibitor of poly (ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways
-
SZABÓ C., WONG H.R., BAUER P.I. et al. (1997) Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, and inhibitor of poly (ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways. Int J Oncol 10, 1093.
-
(1997)
Int J Oncol
, vol.10
, pp. 1093
-
-
Szabó, C.1
Wong, H.R.2
Bauer, P.I.3
-
48
-
-
0030870278
-
Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects
-
SZABÓ C., LIM L.H.K., CUZZOCREA S. et al. (1997) Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects. J Exp Med 186, 1041.
-
(1997)
J Exp Med
, vol.186
, pp. 1041
-
-
Szabó, C.1
Lim, L.H.K.2
Cuzzocrea, S.3
-
49
-
-
0030788898
-
Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion
-
CUZZOCREA S., ZINGARELLI B., COSTANTINO G. et al. (1997) Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion. Br J Pharmacol 121, 1065.
-
(1997)
Br J Pharmacol
, vol.121
, pp. 1065
-
-
Cuzzocrea, S.1
Zingarelli, B.2
Costantino, G.3
-
50
-
-
0030842946
-
Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischaemia
-
ELIASSON M.J.L., SAMPEI K., MANDIR A.S. et al. (1997) Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischaemia. Nature Med 3, 1089.
-
(1997)
Nature Med
, vol.3
, pp. 1089
-
-
Eliasson, M.J.L.1
Sampei, K.2
Mandir, A.S.3
-
51
-
-
0032127666
-
Role of poly(ADP-ribose) synthetasc activation in inflammation and reperfusion injury
-
in press
-
SZABÓ C. & DAWSON V.L (1998) Role of poly(ADP-ribose) synthetasc activation in inflammation and reperfusion injury. Trends Pharmacol Sci, in press.
-
(1998)
Trends Pharmacol Sci
-
-
Szabó, C.1
Dawson, V.L.2
|