A novel function for the tumor suppressor p16(INK4a): Induction of anoikis via upregulation of the α5β1 fibronectin receptor

Journal of Cell Biology

Volumn 150, Issue 6, 2000, Pages 1467-1477

  Plath, Thomas ^a   Detjen, Katharina ^a   Welzel, Martina ^a   Von Marschall, Zofia ^a   Murphy, Derek ^a   Schirner, Michael ^a   Wiedenmann, Bertram ^a   Rosewicz, Stefan ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Anoikis; Fibronectin; Integrin; Tumor suppressor p16(INK4a); Tumorigenicity

Indexed keywords

CYCLIN D; CYCLIN DEPENDENT KINASE; DNA FRAGMENT; FIBRONECTIN; FIBRONECTIN RECEPTOR; INTEGRIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYMACON; PROTEIN P16;

ANCHORAGE INDEPENDENT GROWTH; APOPTOSIS; ARTICLE; CARCINOGENICITY; CARCINOMA CELL; CELL ADHESION; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; ENZYME INHIBITION; GENE FUNCTION; HUMAN; HUMAN CELL; PANCREAS CARCINOMA; PRIORITY JOURNAL; RECEPTOR UPREGULATION; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; CARRIER PROTEINS; CELL ADHESION; CELL DIVISION; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASES; DOWN-REGULATION; FIBRONECTINS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; KIDNEY; LIVER; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; PHENOTYPE; PROTO-ONCOGENE PROTEINS; RECEPTORS, FIBRONECTIN; SKIN; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0034683576     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.150.6.1467     Document Type: Article

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