Defective Cytochrome c-dependent Caspase Activation in Ovarian Cancer Cell Lines due to Diminished or Absent Apoptotic Protease Activating Factor-1 Activity

Journal of Biological Chemistry

Volumn 276, Issue 36, 2001, Pages 34244-34251

  Wolf, Beni B ^a   Schuler, Martin ^a   Li, Wei ^a   Eggers Sedlet, Beth ^a   Lee, Wilson ^a   Tailor, Pankaj ^b   Fitzgerald, Patrick ^a   Mills, Gordon B ^c   Green, Douglas R ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL ACTIVATION; ENZYMES; OLIGOMERS; TUMORS;

CELL LINES;

BIOCHEMISTRY;

CASPASE; CYTOCHROME C; PROTEIN BCL 2; PROTEINASE ACTIVATED RECEPTOR 1; APAF1 PROTEIN, HUMAN; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASP3 PROTEIN, HUMAN; CASP7 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE 3; CASPASE 7; CASPASE 9; GRANZYME; GZMB PROTEIN, HUMAN; ISOPROTEIN; PROTEIN; SERINE PROTEINASE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL FREE SYSTEM; CELL KILLING; CELL SURVIVAL; ENZYME ACTIVATION; GENE MUTATION; HUMAN; HUMAN CELL; MALIGNANT TRANSFORMATION; MITOCHONDRIAL MEMBRANE; OLIGOMERIZATION; OVARY CANCER; PRIORITY JOURNAL; PROTEIN DEGRADATION; ULTRAVIOLET RADIATION; CELL CULTURE; CELL LINE; EPITHELIUM CELL; FEMALE; GENETIC TRANSFECTION; GENETICS; METABOLISM; MUTATION; OVARY; OVARY TUMOR; PATHOLOGY; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BLOTTING, WESTERN; CASPASE 3; CASPASE 7; CASPASE 9; CASPASES; CELL LINE; CELL-FREE SYSTEM; CYTOCHROME C GROUP; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; EPITHELIAL CELLS; FEMALE; GRANZYMES; HUMANS; MUTATION; OVARIAN NEOPLASMS; OVARY; PROTEIN ISOFORMS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERINE ENDOPEPTIDASES; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035823503     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011778200     Document Type: Article

References (32)

1. Wolf, B. B., and Green, D. R. (1999) J. Biol. Chem. 274, 20049-20052
2. Ashkenazi, A., and Dixit, V. M. (1998) Science 281, 1305-1308
3. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. (1997) Cell 91, 470-489
4. Zou, H., Li, Y., Liu, X., and Wang, X. (1999) J. Biol. Chem. 274, 11549-11556
5. Martin, S. J., and Green, D. R. (1996) Cell 82, 349-352
6. Yang, E., and Korsmeyer, S. J. (1996) Blood 88, 386-401
7. Bruey, J.-M., Ducasse, C., Bonniaud, P., Ravagnan, L., Susin, S. A., Diaz-Latoud, C., Gurbuxani, S., Arrigo, A.-P., Kroemer, G., Solary, E., and Garrido, C. (2000) Nat. Cell Biol. 2, 645-652
8. Soengas, M. S., Capodieci, P., Polsky, D., Mora, J., Esteller, M., Opitz-Araya, X., McCombie, R., Herman, J. G., Gerald, W. L., Lazebnik, Y. A., Cordon-Cardo, C., and Lowe, S. W. (2001) Nature 409, 207-211
9. Saleh, A., Srinivasula, S. M., Balkir, L., Robbins, P. D., and Alnemri, E. S. (2000) Nat. Cell Biol. 2, 476-483
10. Beere, H. M., Wolf, B. B., Cain, K., Mosser, D. D., Mahboubi, A., Kuwana, T., Tailor, P., Morimoto, R. I., Cohen, G. M., and Green, D. R. (2000) Nat. Cell Biol. 2, 469-475
11. Pandy, P., Saleh, A., Nakazawa, A., Kumar, S., Srinivasula, S. M., Kumar, V., Weichselbaum, R., Nalin, C., Alnemri, E. S., Kufe, D., and Kharbanda, S. (2000) EMBO J. 19, 4310-4322
12. Cardone, M. H., Roy, N., Stennicke, H. R., Salvesen, G. S., Franke, T. F., Stanbridge, E., Frisch, S., and Reed, J. C. (1998) Science 282, 1318-1321
13. Deveraux, Q. L., Takahashi, R., Salvesen, G. S., and Reed, J. C. (1997) Nature 388, 300-304
14. Soengas, M. S., Alarcon, R. M., Yoshida, H., Giaccia, P. J., Hakem, R., Mak, T. W., and Lowe, S. W. (1999) Science 284, 156-159
15. Thigpen, J. T. (2000) in Clinical Oncology (Abeloff, M. D., Armitage, J. O., Lichter, A. S., and Niederhuber, J. E., eds) 2nd Ed., pp. 2016-2040, Chrchill Livingstone, New York
16. Auersperg, N., Edelson, M. I., Mok, S. C., Johnson, S. W., and Hamilton, T. C. (1998) Semin. Oncol. 25, 281-304
17. Srinivasa, S. M., Ahmad, M., Fernandes-Alnemri, T., and Alnemri, E. S. (1998) Mol. Cell 1, 949-957
18. Benedict, M. A., Hu, Y., Inohara, N., and Nunez, G. (2000) J. Biol. Chem. 275, 8461-8468
19. Yoshida, H., Kong, Y.-K., Elia, A. J., Hakem, A., Hakem, R., Penninger, J. M., and Mak, T. W. (1998) Cell 94, 739-750
20. Shayesteh, L., Lu, Y., Kuo, W.-L., Baldocchi, R., Godfrey, T., Collins, C., Pinkel, D., Powell, B., Mills, G. B., and Gray, J. W. (1999) Nat. Genet. 21, 99-102
21. Wolf, B. B., Goldstein, J. C., Stennicke, H. R., Beere, H., Amarante-Mendes, G. P., Salvesen, G. S., and Green, D. R. (1999) Blood 94, 1683-1692
22. Wolf, B. B., Schuler, M., Echeverri, F., and Green, D. R. (1999) J. Biol. Chem. 274, 30651-30656
23. Li, B., and Dou, Q. P. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 3850-3855
24. Hahn, C., Hirsch, B., Jahnke, D., Durkop, H., and Stein, S. (1999) Biochem. Biophys. Res. Commun. 261, 746-749
25. Bala, S., Oliver, H., Renault, B., Montgomery, K., Dutta, S., Rao, P., Houldsworth, J., Kucherlapati, R., Wang, X., Chaganti, R. S. K., and Murty, V. V. V. S. (2000) Genes Chromosomes Cancer 28, 258-267
26. Yamamoto, H., Gil, J., and Perucho, M. (2000) Cell Death Differ. 7, 238-240
27. Lynch, H. T., Casey, M. J., Lynch, J., White, T. E. K., and Godwin, A. K. (1998) Semin. Oncol. 25, 265-280
28. Jaattela, M. (1999) Exp. Cell Res. 248, 30-43
29. Perkins, C., Kim, C. N., Fang, G., and Bhalla, K. N. (1998) Cancer Res. 58, 4561-4566
30. Chauhan, D., Hideshima, T., Rosen, S., Reed, J. C., Kharbanda, S., and Anderson, K. C. (2001) J. Biol. Chem. 276, 24453-24456
31. Kasibhatla, S., Brunner, T., Genesier, L., Echeverri, F., Mahboubi, A., and Green, D. R. (1998) Mol. Cell 1, 543-551
32. Harwood, F. G., Kasibhatla, S., Petak, I., Vernes, R., Green, D. R., and Houghton, J. A. (2000) J. Biol. Chem. 275, 10023-10029