Efficacy of curcumin in the management of chronic anterior uveitis

Phytotherapy Research

Volumn 13, Issue 4, 1999, Pages 318-322

  Lal, B ^a   Kapoor, A K ^a   Asthana, O P ^b   Agrawal, P K ^a   Prasad, R ^a   Kumar, P ^b   Srimal, R C ^c  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

^c CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Chronic uveitis; Clinical trial; Curcuma longa; Curcumin

Indexed keywords

CURCUMIN; TUBERCULOSTATIC AGENT;

ADULT; AGED; ARTICLE; CATARACTOGENESIS; CLINICAL TRIAL; DRUG EFFICACY; FEMALE; FOLLOW UP; GLAUCOMA; HUMAN; IRIDOCYCLITIS; MAJOR CLINICAL STUDY; MALE; OPTIC NERVE LESION; ORAL DRUG ADMINISTRATION; RECURRENCE RISK; RETINA MACULA EDEMA; UVEITIS; VEIN OCCLUSION; VISUAL IMPAIRMENT;

ADULT; AGED; CHRONIC DISEASE; CURCUMIN; FEMALE; HUMANS; MALE; MIDDLE AGED; TREATMENT OUTCOME; UVEITIS, ANTERIOR;

CURCUMA LONGA;

EID: 0033062493     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1573(199906)13:4<318::AID-PTR445>3.0.CO;2-7     Document Type: Article

References (37)

1. 4 formation in rat peritoneal polymorphonuclear neutrophils (PMNL). Planta Med. 58, 226-227.
2. Ammon, H. P. T., Safayhi, H., Mack, T., and Sabierai, J. (1993). Mechanism of antinflammatory actions of curcumin and boswellic acid. J. Ethnopharmacol., 38, 113-119.
3. Anto, R. J., Kuttan, G., Babu, K. V. D., Rajasekharan, K. N., and Kuttan, R. (1996). Anti-tumour and free radical scavenging activity of synthetic curcuminoids. Int. J. Pharmac., 131, 1-7.
4. Awasthi, S., Srivastava, S. K., Piper, J. T., Singhal, S. S., Chaubey, M., and Awasthi, Y. C. (1996). Curcumin protects against 4-hydroxy-2-trans-nonenal-induced cataract formation in rat lenses. Am. J. Clin. Nutr. 64, 761-766.
5. Babu, P. S., and Srinivasan, K. (1993). Influence of dietary spices on adrenal steroidogenesis in rats. Nutr. Res., 13, 435-444.
6. Bates, S. E., Duen, J. Y., and Tranum, B. L. (1979). Immunological skin testing and interpretation. A plea for uniformity. Cancer 43, 2306-2311.
7. Bloch-Mitchell, E., and Nussenblatt, R. B. (1987). International uveitis study group recommendations for the evaluation of intraocular inflammatory disease. Am. J. Ophthalmol., 103, 234-235.
8. Brouet, I., and Ohshim, H. (1995). Curcumin, an anti-tumour promoter and antiinflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem. Biophys. Res. Commun. 206, 533-540.
9. Chang, H., and But, P. P. (1987). Pharmacology and Applications of Chinese Materia Medica. 2, World Scientific, Singapore.
10. Colombe, B. W. (1994). Histocompatibility testing. In, Basic and Clinical Immunology, ed. by D. P. Stites, A. I. Terr, and T. G. Parslow, 8th Edn, pp. 237-255. Prentice-Hall, London.
11. Deodhar, S. D., Srimal, R. C., and Dhawan, B. N. (1980). Antirheumatic activity of Curcumin. Proc. World Conference on Clinical Pharmacology and Therapeutics, London, Abstract No. 0668. Macmillan Publishers Ltd., London
12. Dikshit, M., Rastogi, L., Shukla, R., and Srimal, R. C. (1995). Prevention of ischemia-induced biochemical changes by curcumin and quinidine in the cat heart. Indian. J. Med. Res. 101, 31-35.
13. Flynn, D. L., and Rafferty, M. F. (1986). Inhibition of 5-HETE formation in intact human neutrophils by naturally occurring diarylheptanoids. Prostagland. Leukotrien. Med. 22, 357-360.
14. Ghatak, A., Srivastava, J. S., Gaur, S. P. S., Asthana, O. P., Srimal, R. C., and Dhawan, B. N. (1991). Evidence for efficacy of curcumin in rheumatoid arthritis. J. Assoc. Physic. India 39, 137.
15. Ghatak, N., and Basu, N. (1972). Sodium curcuminate as an effective antiinflammatory agent. Indian. J. Exp. Biol. 10, 235-236.
16. Grinberg, L. N., Shalev, O., Tonnesen, H. H., and Rachmilewitz, E. A. (1996). Studies on curcumin and curcuminoids.26. Antioxidant effects of curcumin on the red blood cell membrane. Int. J. Pharmac. 132, 251-257.
17. Hogan, M., Kimura, S. J., and Thygeson, P. (1959). Signs and symptoms of uveitis. I. Anterior uveitis. Am. J. Ophthalmol. 47, 155-170.
18. Huang, M. T., Lysz, T., Ferraro, T., Abidi, T. F., Kaskin, J. D., and Conney, A. H. (1991). Inhibitory effect of curcumin in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res. 51, 813-819.
19. Kimura, S. J., Thygeson, P., and Hagen, M. (1959). Signs and symptoms of uveitis. II. Classification of the posterior manifestations of uveitis. Am. J. Ophthalmol. 47, 171-176.
20. Mukhopadhyaya, A., Basu, N., Ghatak, N., and Gujral, P. K. (1982). Antiinflammatory and irritant activities of curcumin analogues in rats. Agents Actions 12, 508-515.
21. Rajakumar, D. V., and Rao, M. N. A. (1994). Anti-oxidant properties of dehydrozingerone and curcumin in rat brain homogenates. Mol. Cell. Biochem. 140, 73-79.
22. Sharma, O. P. (1976). Antioxidant activity of curcumin and related compounds. Biochem. Pharmacol. 25, 1811-1812.
23. South, E. H., Exon, J. H., and Hendrix, K. (1997). Dietary curcumin enhances antibody response in rats. Immunopharmacol Immunotoxicol. 19, 105-119.
24. Srimal, R. C., and Dhawan, B. N. (1973). Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J. Pharm. Pharmacol. 25, 447-452.
25. Srimal, R. C., and Dhawan, B. N. (1985). Pharmacological and clinical studies on Curcuma longa. In, Development of Unani Drugs from Herbal sources and the role of Elements in their Mechanism of Action, ed. by R. B. Arora, pp. 131-142. Hamdard National Foundation Monograph. Hamdard National Foundation, New Delhi.
26. Srimal, R. C., Khanna, N. M., and Dhawan, B. N. (1971). A preliminary report on the antiinflammatory activity of curcumin. Indian. J. Pharmacol. 3, 10.
27. Srinivas, C., and Prabhakaran, K. V. S. (1989). Haridra (Curcuma longa) and its effect on Abhisayanda (conjunctivitis). Anc. Sci. Life 8, 279-283.
28. Srivastava, R., and Srimal, R. C. (1985). Modification of certain inflammation induced biochemical changes by curcumin. Indian J. Med. Res. 81, 215-223.
29. Srivastava, R., Dikshit, M., Srimal, R. C., and Dhawan, B. N. (1985). Antithrombotic effect of curcumin. Thromb. Res. 40, 413-418.
30. Srivastava, R., Puri, V., Srimal, R. C., and Dhawan, B. N. (1986). Effects of curcumin on platelet aggregation and vascular prostacyclin synthesis. Arzneimittel Forsch. 36, 715-717.
31. Srivastava, R., and Srimal, R. C. (1990a). On the mechanism of action of Curcumin, a nonsteroidal anti-inflammatory agent. Indian J. Pharmacol. 22, 2.
32. Srivastava, R., and Srimal, R. C. (1990b). Action of Curcumin on free radical mechanisms during acute inflammation in rats. Indian J. Pharmacol. 22, 47.
33. Vyrenkova, T. E., and Oleinichenko, E. G. (1990). The importance of subcutaneous tuberculin administration in early diagnosis of tuberculous uveitis. Probl. Tuberk. 1, 59-62.
34. Wood, A. C. (1960). Modern concepts of the etiology of uveitis. Am. J. Ophthalmol. 50, 1170-1187.
35. Woods, A. C., and Abrahams, I. W. (1961). Uveitis survey. Am. J. Ophthalmol. 51, 761-780.
36. Yano, S., Terai, M., Shimizu, K. L. et al. (1996). Antiallergic activity of extracts from Curcuma longa: Active compounds and mechanism of actions. Proc. 2nd Int. Cong. on Phytomedicine. Munich, Germany, Sept. 11-14, p. SL40. German Society of Phytotherapy and ESCOP, Munich, Germany.
37. Zhao, B. L., Li, X. J., He, R. G., Cheng, S. J., and Xin, W. J. (1989). Scavenging effect of extracts of green tea and natural anti-oxidants on active oxygen radicals. Cell Biophys. 14, 175-185.