Curcumin protects against 4-hydroxy-2-trans-nonenal-induced cataract formation in rat lenses

American Journal of Clinical Nutrition

Volumn 64, Issue 5, 1996, Pages 761-766

  Awasthi, Sanjay ^a   Srivatava, Sanjay K ^a   Piper, John T ^a   Singhal, Sharad S ^a   Chaubey, Meena ^a   Awasthi, Yogesh C ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

4 hydroxynonenal; antioxidants; cataract prevention; Curcumin; glutathione S transferase

Indexed keywords

CURCUMIN; GAMMA GLUTAMYLTRANSFERASE;

ANIMAL TISSUE; ARTICLE; CATARACTOGENESIS; DETOXIFICATION; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; LENS EPITHELIUM; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PROTECTION; RAT; VISUAL IMPAIRMENT;

ANIMALIA; CURCUMA LONGA; ZEA MAYS;

EID: 0029909051     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/64.5.761     Document Type: Article

References (35)

1. Giblin FJ, Padgaonkar VA, Leverenz VR, et al. Nuclear light scattering, disulfide formation and membrane damage in lenses of older guinea pigs treated with hyperbaric oxygen. Exp Eye Res 1995;60: 219-35.
2. Adamsons I, Munoz B, Enger C, Taylor HR. Prevalence of lens opacities in surgical and general populations. Arch Ophthalmol 1991;109:993-7.
3. Spector A, Wang GM, Wang RR. The prevention of cataract caused by oxidative stress in cultured rat lenses II. Early effects of photochemical stress and recovery. Exp Eye Res 1993;57:659-67.
4. 2 and photochemically induced cataract, Curr Eye Res 1993;12:163-79.
5. Bhatnagar A, Ansari NH, Zacarias A, Srivastava SK. Digital image analysis of cultured rat lens during oxidative stress induced cataractogenesis. Exp Eye Res 1993;57:385-91.
6. Spector A, Wang GM, Wang RR, Li WC, Kleiman NJ. A brief photochemically induced oxidative insult causes irreversible lens damage and cataract II. Mechanism of action. Exp Eye Res 1995;60: 483-93.
7. Bhuyan KC, Bhuyan DK. Molecular mechanism of cataractogenesis: II. Evidence of lipid peroxidation and membrane damage. Vol 2. In: Greenwald RA, Cohen G, eds. Oxy radicals and their scavenger systems. New York: Elsevier Science Publishing, 1983:349-56.
8. Kehrer JP. Free radicals as mediators of tissue injury and disease. Crit Rev Toxicol 1993;23:21-48.
9. Varma SD, Devamanoharan PS, Morris SM. Prevention of cataracts by nutritional and metabolic antioxidants. Crit Rev Food Sci Nutr 1995;35:111-29.
10. Varma SD. Scientific basis for medical therapy of cataracts by antioxidants. Am J Clin Nutr 1991;53(suppl):335S-45S.
11. Robertson JMcD, Donner AP, Trevithick JR. A possible role for vitamin C and E in cataract prevention. Am J Clin Nutr 1991; 53(suppl):346S-51S.
12. Devamanoharan PS, Henein M, Morris S, Ramchandran S, Richards RD, Varma SD. Prevention of selinite cataract by vitamin C. Exp Eye Res 1991;52:563-8.
13. Elizabeth K, Rao MNA. Oxygen radical scavenging activity of curcumin. Int J Pharmacol 1990;58:237-40.
14. Sharma OP. Antioxidant activity of curcumin and related compounds. Biochem Pharmacol 1976;26:1811-2.
15. Susan M, Rao MNA. Induction of glutathione S-transferase activity by curcumin in mice. Drug Res 1992;42:962-4.
16. Awasthi YC, Dao DD, Saneto RP. Interrelationship between cationic and anionic forms of glutathione S-transferases of human liver. Biochem J 1980;191:1-10.
17. Bieri JG, Stoewsand GS, Phillips RW, Knapka JJ. Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies. J Nutr 1977;107:1340-8.
18. Khan MF, Srivastava SK, Singhal SS, et al. Iron induced lipid peroxidation in rat liver is accompanied with preferential induction of glutathione S-transferase 8-8 isozyme. Toxicol Appl Pharmacol 1995; 131:63-72.
19. Ahmad H, Sharma R, Mansour A, Awasthi YC. t-Butylated hydroxytoluene enhances intracellular levels of glutathione and related enzymes of rat lens in vitro organ culture. Exp Eye Res 1992;54:41-8.
20. Dunnett CW. A multiple comparison procedure for comparing several treatments with a control. J Am Stat Assoc 1955;50:1096-121.
21. Talalay P, DeJong MJ, Prochaska HJ. Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis. Proc Natl Acad Sci U S A 1988;85: 8261-5.
22. Alin P, Danielson UH, Mannervik B. 4-Hydroxy-2-enals are substrates for glutathione S-transferase. FEBS Lett 1985;179:267-70.
23. Zimniak P, Eckles MA, Saxena M, Awasthi YC. A subgroup of class a glutathione S-transferases: cloning of cDNA for mouse lung glutathione S-transferase GST 5.7. FEBS Lett 1992;313:173-6.
24. Zimniak P, Singhal SS, Srivastava SK, et al. Estimation of genomic complexity, heterologous expression and enzymatic characterization of mouse glutathione S-transferase mGSTA4-4 (GST 5.7). J Biol Chem 1994;269:992-1000.
25. Srivastava SK, Singhal SS, Bajpai KK, Chaubey M, Ansari NH, Awasthi YC. A group of novel glutathione S-transferase isozymes showing high activity towards 4-hydroxy-2-nonenal are present in bovine ocular tissues. Exp Eye Res 1994;59:151-9.
26. Singhal SS, Awasthi S, Srivastava SK, Zimniak P, Ansari NH, Awasthi YC. Novel human ocular glutathione S-transferases with high activity towards 4-hydroxynonenal. Invest Ophthalmol Vis Sci 1995;36:142-50.
27. Babizhayev MA, Deyev AI. Free radical oxidation of lipids and thiol groups in genesis of cataract. Biophysics 1986;31:119-25.
28. Babizhayev MA, Deyev AI, Linberg LF. Lipid peroxidation as a possible cause of cataract. Mech Ageing Dev 1988;44:69-89.
29. Pacifici RE, Davies KJA. Protein, lipid and DNA repair systems in oxidative stress: the free radical theory of aging revisited. Gerontology 1991;37:166-80.
30. Kagah VE. Lipid peroxidation in biomembranes. Boca Raton, FL: CRC Press, 1988.
31. Awasthi YC, Zimniak P, Singhal SS, Awasthi S. Physiological role of glutathione S-transferases in protection mechanisms against lipid peroxidation, a commentary. Biochem Arch 1995;11:47-54.
32. Singhal SS, Zimniak P, Awasthi S, et al. Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. Arch Biochem Biophys 1994;311:242-50.
33. Srivastava SK, Singhal SS, Awasthi S, Pikula S, Ansari NH, Awasthi YC. A glutathione S-transferases isozyme (bGST 5.8) involved in the metabolism of 4-hydroxy-2-trans-nonenal is localized in bovine lens epithelium. Exp Eye Res(in press).
34. Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 1991;11:81-128.
35. Li WC, Kuszak JR, Dunn K, et al. Lens epithelial cell apoptosis appears to be a common cellular basis for non congenital cataract development in humans and animals. J Cell Biol 1995;130:169-81.