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Volumn 30, Issue 4, 1998, Pages 445-456

Mechanisms of anticarcinogenic properties of curcumin: The effect of curcumin on glutathione linked detoxification enzymes in rat liver

Author keywords

4 hydroxynonenal; Curcumin; Glutathione peroxidase; Glutathione S transferase; Lipid peroxidation

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 4 HYDROXYNONENAL; CURCUMIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; THIOL DERIVATIVE;

EID: 0031799304     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(98)00015-6     Document Type: Article
Times cited : (235)

References (37)
  • 1
    • 0027171266 scopus 로고
    • Oxidants, antioxidants and the degenerative diseases of aging
    • Ames B.N., Shigenaga M.K., Hagen T.M. Oxidants, antioxidants and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA. 90:1993;7915-7922.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7915-7922
    • Ames, B.N.1    Shigenaga, M.K.2    Hagen, T.M.3
  • 2
    • 0021934758 scopus 로고
    • Chemoprevention of cancer
    • Wattenberg L.W. Chemoprevention of cancer. Cancer Res. 45:1985;1-8.
    • (1985) Cancer Res. , vol.45 , pp. 1-8
    • Wattenberg, L.W.1
  • 3
  • 4
    • 0026659471 scopus 로고
    • Protective role of aqueous turmeric extract against mutagenicity of direct-acting carcinogens as well as benzo[a]pyrene induced genotoxicity and carcinogenicity
    • Azuine M.A., Kayal J.J., Bhide S.V. Protective role of aqueous turmeric extract against mutagenicity of direct-acting carcinogens as well as benzo[a]pyrene induced genotoxicity and carcinogenicity. J. Cancer Res. Clin. Oncol. 118:1992;447-452.
    • (1992) J. Cancer Res. Clin. Oncol. , vol.118 , pp. 447-452
    • Azuine, M.A.1    Kayal, J.J.2    Bhide, S.V.3
  • 5
    • 0028073507 scopus 로고
    • Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice
    • Huang M.T., Lou Y.R., Ma W., Newmark H.L., Reuhl K.R., Conney A.H. Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice. Cancer Res. 54:1994;5841-5847.
    • (1994) Cancer Res. , vol.54 , pp. 5841-5847
    • Huang, M.T.1    Lou, Y.R.2    Ma, W.3    Newmark, H.L.4    Reuhl, K.R.5    Conney, A.H.6
  • 6
    • 0028872989 scopus 로고
    • Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound
    • Rao C.V., Rivenson A., Simi B., Reddy B.S. Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound. Cancer Res. 55:1995;259-266.
    • (1995) Cancer Res. , vol.55 , pp. 259-266
    • Rao, C.V.1    Rivenson, A.2    Simi, B.3    Reddy, B.S.4
  • 7
    • 0001952670 scopus 로고    scopus 로고
    • Mechanisms of anticarcinogenic effects of antioxidant nutrients
    • In: R.R. Watson (Ed.) CRC Press, Boca Ratan, FL
    • Y.C. Awasthi, S.S. Singhal, S. Awasthi. Mechanisms of anticarcinogenic effects of antioxidant nutrients. In: R.R. Watson (Ed.), Nutrition and Cancer. CRC Press, Boca Ratan, FL, 1996, pp. 139-172.
    • (1996) Nutrition and Cancer , pp. 139-172
    • Awasthi, Y.C.1    Singhal, S.S.2    Awasthi, S.3
  • 8
    • 0026615189 scopus 로고
    • Inhibitory effects of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethyl-benz[a]anthracene
    • Huang M.T., Wang Z.Y., Georgiadis C.A., Laskin J.D., Conney A.H. Inhibitory effects of curcumin on tumor initiation by benzo[a]pyrene and 7,12-dimethyl-benz[a]anthracene. Carcinogeneis. 13:1992;2183-2186.
    • (1992) Carcinogeneis , vol.13 , pp. 2183-2186
    • Huang, M.T.1    Wang, Z.Y.2    Georgiadis, C.A.3    Laskin, J.D.4    Conney, A.H.5
  • 9
    • 0345680855 scopus 로고
    • Inhibition of the mutagenicity of Bay-Region diol-epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: Exceptional activity of ellagic acid
    • Wood A.W., Huang M.T., Chang R.L., Newmark H.L., Lehr R.E., Yagi H., Sayer J.M., Jernia D.M., Conney A.H. Inhibition of the mutagenicity of Bay-Region diol-epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: exceptional activity of ellagic acid. Proc. Natl. Acad. Sci. USA. 79:1982;5513-5517.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 5513-5517
    • Wood, A.W.1    Huang, M.T.2    Chang, R.L.3    Newmark, H.L.4    Lehr, R.E.5    Yagi, H.6    Sayer, J.M.7    Jernia, D.M.8    Conney, A.H.9
  • 10
    • 0026740957 scopus 로고
    • Hydrolyzable tannins: Potent inhibitors of hydroperoxide production and tumor promotion in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate in vivo
    • Gali H.U., Perchellet E.M., Klish D.S., Johnson J.M., Perchellet J.P. Hydrolyzable tannins: potent inhibitors of hydroperoxide production and tumor promotion in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate in vivo. Int. J. Cancer. 51:1992;425-432.
    • (1992) Int. J. Cancer , vol.51 , pp. 425-432
    • Gali, H.U.1    Perchellet, E.M.2    Klish, D.S.3    Johnson, J.M.4    Perchellet, J.P.5
  • 11
    • 0021341107 scopus 로고
    • A hypothesis for dietary components as blocking agents of chemical carcinogenesis: plant phenolics and pyrrole pigments
    • H.L. Newmark, A hypothesis for dietary components as blocking agents of chemical carcinogenesis: plant phenolics and pyrrole pigments, Nutr. Cancer. 6 (1984) 58-70.
    • (1984) Nutr. Cancer. , vol.6 , pp. 58-70
    • Newmark, H.L.1
  • 12
    • 0025020674 scopus 로고
    • Oxygen radical scavenging activity of curcumin
    • Kunchandy E., Rao M.N.A. Oxygen radical scavenging activity of curcumin. Int. J. Pharmaceut. 58:1990;237-240.
    • (1990) Int. J. Pharmaceut. , vol.58 , pp. 237-240
    • Kunchandy, E.1    Rao, M.N.A.2
  • 13
    • 0022021733 scopus 로고
    • Modification of certain inflammation induced biochemical changes by curcumin
    • Srivastava R., Srimal R.C. Modification of certain inflammation induced biochemical changes by curcumin. Indian J. Med. Res. 81:1985;215-223.
    • (1985) Indian J. Med. Res. , vol.81 , pp. 215-223
    • Srivastava, R.1    Srimal, R.C.2
  • 16
    • 0018116175 scopus 로고
    • Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo[a]pyrene by dietary antioxidants
    • Benson A.M., Batzinger R.P., Ou S.Y., Bueding E., Cha Y.N., Talalay P. Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo[a]pyrene by dietary antioxidants. Canc. Res. 38:1978;4486-4495.
    • (1978) Canc. Res. , vol.38 , pp. 4486-4495
    • Benson, A.M.1    Batzinger, R.P.2    Ou, S.Y.3    Bueding, E.4    Cha, Y.N.5    Talalay, P.6
  • 17
    • 0024781837 scopus 로고
    • Mechanisms of induction of enzymes that protect against chemical carcinogenesis
    • Talalay P. Mechanisms of induction of enzymes that protect against chemical carcinogenesis. Adv. Enzyme Reg. 28:1989;237-250.
    • (1989) Adv. Enzyme Reg. , vol.28 , pp. 237-250
    • Talalay, P.1
  • 18
    • 0026628343 scopus 로고
    • Induction of glutathione S-transferase activity by curcumin in mice
    • Susan M., Rao M.N.A. Induction of glutathione S-transferase activity by curcumin in mice. Drug Res. 42:1992;962-964.
    • (1992) Drug Res. , vol.42 , pp. 962-964
    • Susan, M.1    Rao, M.N.A.2
  • 19
    • 0029561598 scopus 로고
    • The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
    • Hayes J.D., Pulford D.J. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit. Rev. Biochem. Molec. Biol. 30:1995;445-600.
    • (1995) Crit. Rev. Biochem. Molec. Biol. , vol.30 , pp. 445-600
    • Hayes, J.D.1    Pulford, D.J.2
  • 20
    • 0028292679 scopus 로고
    • Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues
    • Singhal S.S., Zimniak P., Awasthi S., Piper J.T., He N.G., Teng J.I., Petersen D.R., Awasthi Y.C. Several closely related glutathione S-transferase isozymes catalyzing conjugation of 4-hydroxynonenal are differentially expressed in human tissues. Arch. Biochem. Biophys. 311:1994;242-250.
    • (1994) Arch. Biochem. Biophys. , vol.311 , pp. 242-250
    • Singhal, S.S.1    Zimniak, P.2    Awasthi, S.3    Piper, J.T.4    He, N.G.5    Teng, J.I.6    Petersen, D.R.7    Awasthi, Y.C.8
  • 21
    • 0029032156 scopus 로고
    • Glutathione S-transferase 8-8 is localized in smooth muscle cells of rat aorta is induced in an experimental model of atherosclerosis
    • Misra P., Srivastava S.K., Singhal S.S., Awasthi S., Awasthi Y.C., Boor P.J. Glutathione S-transferase 8-8 is localized in smooth muscle cells of rat aorta is induced in an experimental model of atherosclerosis. Toxicol. Appl. Pharmacol. 133:1995;27-33.
    • (1995) Toxicol. Appl. Pharmacol. , vol.133 , pp. 27-33
    • Misra, P.1    Srivastava, S.K.2    Singhal, S.S.3    Awasthi, S.4    Awasthi, Y.C.5    Boor, P.J.6
  • 23
    • 0022534948 scopus 로고
    • Rat glutathione transferase 8-8, an enzyme efficiently detoxifying 4-hydroxyalk-2-enals
    • Jensson H., Guthenberg C., Alin P., Mannervik B. Rat glutathione transferase 8-8, an enzyme efficiently detoxifying 4-hydroxyalk-2-enals. FEBS Lett. 203:1986;207-209.
    • (1986) FEBS Lett. , vol.203 , pp. 207-209
    • Jensson, H.1    Guthenberg, C.2    Alin, P.3    Mannervik, B.4
  • 24
    • 0028069416 scopus 로고
    • Estimation of genomic complexity, heterologous expression, and enzymatic characterization of mouse glutathione S-transferase mGSTA4-4 (GST 5.7)
    • Zimniak P., Singhal S.S., Srivastava S.K., Awasthi S., Sharma R., Hayden J.B., Awasthi Y.C. Estimation of genomic complexity, heterologous expression, and enzymatic characterization of mouse glutathione S-transferase mGSTA4-4 (GST 5.7). J. Biol. Chem. 269:1994;992-1000.
    • (1994) J. Biol. Chem. , vol.269 , pp. 992-1000
    • Zimniak, P.1    Singhal, S.S.2    Srivastava, S.K.3    Awasthi, S.4    Sharma, R.5    Hayden, J.B.6    Awasthi, Y.C.7
  • 25
    • 0026553336 scopus 로고
    • Chemoprotective effect of turmeric against stomach and skin tumors induced by chemical carcinogens in swiss mice
    • Azuine M.A., Bhide S.V. Chemoprotective effect of turmeric against stomach and skin tumors induced by chemical carcinogens in swiss mice. Nutr. Cancer. 17:1992;77-83.
    • (1992) Nutr. Cancer , vol.17 , pp. 77-83
    • Azuine, M.A.1    Bhide, S.V.2
  • 26
    • 0016275313 scopus 로고
    • Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
    • Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249:1974;7130-7139.
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 27
    • 0021950853 scopus 로고
    • 4-Hydroxyalk-2-enals are substrates for glutathione transferase
    • Alin P., Danielson U.H., Mannervik B. 4-Hydroxyalk-2-enals are substrates for glutathione transferase. FEBS Lett. 179:1985;267-270.
    • (1985) FEBS Lett. , vol.179 , pp. 267-270
    • Alin, P.1    Danielson, U.H.2    Mannervik, B.3
  • 28
    • 0016769483 scopus 로고
    • Purification and properties of human erythrocyte glutathione peroxidase
    • Awasthi Y.C., Beutler E., Srivastava S.K. Purification and properties of human erythrocyte glutathione peroxidase. J. Biol. Chem. 250:1975;5144-5149.
    • (1975) J. Biol. Chem. , vol.250 , pp. 5144-5149
    • Awasthi, Y.C.1    Beutler, E.2    Srivastava, S.K.3
  • 29
    • 0021359583 scopus 로고
    • Gamma-glutamylcysteine synthetase. Interactions of an essential sulfhydryl group
    • Seelig G.F., Meister A. Gamma-glutamylcysteine synthetase. Interactions of an essential sulfhydryl group. J. Biol. Chem. 259:1984;3534-3538.
    • (1984) J. Biol. Chem. , vol.259 , pp. 3534-3538
    • Seelig, G.F.1    Meister, A.2
  • 30
    • 73649194769 scopus 로고
    • Improved method for the determination of blood glutathione
    • Beutler E., Duron O., Kelly B.M. Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 61:1963;882-890.
    • (1963) J. Lab. Clin. Med. , vol.61 , pp. 882-890
    • Beutler, E.1    Duron, O.2    Kelly, B.M.3
  • 31
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 33
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 34
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA. 76:1979;4350-4354.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 36
    • 0344292325 scopus 로고
    • Glutathione peroxidase activity of glutathione S-transferases
    • Prohaska J.R., Ganther H.E. Glutathione peroxidase activity of glutathione S-transferases. Biochem. Biophys. Res. Commun. 102:1977;403-410.
    • (1977) Biochem. Biophys. Res. Commun. , vol.102 , pp. 403-410
    • Prohaska, J.R.1    Ganther, H.E.2
  • 37
    • 0018222291 scopus 로고
    • The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat
    • Holder G.M., Plummer J.L., Ryan A.J. The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat. Xenobiotica. 8:1978;761-768.
    • (1978) Xenobiotica , vol.8 , pp. 761-768
    • Holder, G.M.1    Plummer, J.L.2    Ryan, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.