Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bcl-2 and Bcl-xl

Carcinogenesis

Volumn 23, Issue 1, 2002, Pages 143-150

  Anto, Ruby John ^a   Mukhopadhyay, Asok ^a   Denning, Kate ^a   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CURCUMA LONGA EXTRACT; CURCUMIN; CYCLOOXYGENASE 2; CYTOCHROME C; FLAVORING AGENT; MITOCHONDRIAL ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID;

ACUTE GRANULOCYTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG RESISTANCE; DRUG SAFETY; ENZYME ACTIVATION; ENZYME RELEASE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; TIME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BLOTTING, WESTERN; CARRIER PROTEINS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL SURVIVAL; CURCUMIN; CYCLOOXYGENASE 2; CYTOCHROME C GROUP; DOWN-REGULATION; ENZYME ACTIVATION; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HL-60 CELLS; HUMANS; ISOENZYMES; JURKAT CELLS; MEMBRANE PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTO-ONCOGENE PROTEINS C-BCL-2; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036195104     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/23.1.143     Document Type: Article

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