Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action

Journal of Medicinal Chemistry

Volumn 40, Issue 19, 1997, Pages 3057-3063

  Mazumder, Abhijit ^a   Neamati, Nouri ^a   Sunder, Sanjay ^a   Schulz, Jutta ^b   Pertz, Heinz ^b   Eich, Eckart ^b   Pommier, Yves ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1,7 BIS(3,4 HYDROXYPHENYL) 1,6 HEPTADIENE 3,5 DIONE; ANTIVIRUS AGENT; CURCUMIN; CURCUMIN DERIVATIVE; DIVALENT CATION; ENZYME INHIBITOR; INTEGRASE; INTEGRASE INHIBITOR; NSC 158393; ROSMARINIC ACID; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS ENZYME;

ARTICLE; BINDING KINETICS; DRUG ACTIVITY; DRUG DNA BINDING; DRUG POTENCY; DRUG POTENTIATION; DRUG SYNTHESIS; ENZYME BINDING; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION;

4-HYDROXYCOUMARINS; BASE SEQUENCE; CATECHOLS; CINNAMATES; CURCUMIN; DEPSIDES; DNA, VIRAL; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; KINETICS; MOLECULAR STRUCTURE; OLIGODEOXYRIBONUCLEOTIDES; SUBSTRATE SPECIFICITY;

EID: 0030805998     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970190x     Document Type: Article

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