Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line

Cancer Letters

Volumn 184, Issue 1, 2002, Pages 1-6

  Ramachandran, Cheppail ^a   Fonseca, Hugo B ^a   Jhabvala, Perseus ^a   Escalon, Enrique A ^a   Melnick, Steven J ^a  

^a MIAMI CHILDREN'S HOSPITAL   (United States)

Author keywords

c myc; Curcumin; Human telomerase reverse transcriptase; Real time reverse transcription polymerase chain reaction; Telomerase; Telomerase RNA

Indexed keywords

CURCUMIN; MESSENGER RNA; MYC PROTEIN; RNA DIRECTED DNA POLYMERASE; TELOMERASE; DNA BINDING PROTEIN; ENZYME INHIBITOR; RNA;

APOPTOSIS; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; BREAST TUMOR; CELL CULTURE; COMPARATIVE STUDY; DRUG ANTAGONISM; ENZYMOLOGY; EPITHELIUM CELL; FEMALE; GENETICS; METABOLISM;

BREAST NEOPLASMS; COMPARATIVE STUDY; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; EPITHELIAL CELLS; FEMALE; HUMAN; PROTO-ONCOGENE PROTEINS C-MYC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; SUPPORT, NON-U.S. GOV'T; TELOMERASE; TUMOR CELLS, CULTURED; DNA-BINDING PROTEINS; HUMANS;

CURCUMA LONGA; MINK CELL FOCUS-FORMING VIRUS;

EID: 0037044179     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(02)00192-1     Document Type: Article

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