Relative contribution of nf-κb and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by keratinocytes

Cytokine

Volumn 18, Issue 3, 2002, Pages 168-177

  Grandjean Laquerriere, Alexia ^a   Gangloff, Sophie C ^a   Le Naour, Richard ^a   Trentesaux, Chantal ^a   Hornebeck, William ^a   Guenounou, Moncef ^a  

^a CNRS   (France)

Author keywords

Anti inflammatory effects; NCTC 2544 cell; Transcription factors

Indexed keywords

BETA ACTIN; CURCUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; PYRROLIDINE DITHIOCARBAMATE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; DNA; PYRROLIDINE DERIVATIVE; PYRROLIDINE DITHIOCARBAMIC ACID; THIOCARBAMIC ACID DERIVATIVE;

ARTICLE; ASSAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFECT; ELECTROPHORETIC MOBILITY; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; STEADY STATE; ULTRAVIOLET B RADIATION; BIOSYNTHESIS; CELL LINE; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

BASE SEQUENCE; CELL LINE; CURCUMIN; CYTOKINES; DNA; GENE EXPRESSION; HUMANS; INTERLEUKIN-10; INTERLEUKIN-6; INTERLEUKIN-8; KERATINOCYTES; NF-KAPPA B; PYRROLIDINES; RNA, MESSENGER; THIOCARBAMATES; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA; ULTRAVIOLET RAYS;

EID: 0035997266     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2002.0888     Document Type: Article

References (42)

1. Antioxidant nutrients protect against UVB-induced oxidative damage to DNA of mouse keratinocytes in culture
2. UVA-induced autocrine stimulation of fibroblast-derived collagenase/MMP-1 by interrelated loops of interleukin-1 and interleukin-6
3. Elevated plasma interleukin-1 levels in humans following ultraviolet light therapy for psoriasis
4. Ultraviolet light induces increased circulating interleukin-6 in humans
5. Human keratinocytes are a source for tumor necrosis factor alpha: Evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light
6. The role of nuclear factor-κB in cytokine gene regulation
7. Transcriptional regulation in the immune system: All roads lead to AP-1
8. The inductible transcription activator NF-κB: Regulation by distinct protein subunits
9. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor
10. Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide
11. Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide
12. Regulation of interleukin-8 gene expression
13. Isolation of the human interleukin 10 promoter Characterization of the promoter activity in Burkitt's lymphoma cell lines
14. Up-regulation of monocytic IL-10 by tumor necrosis factor-a and cAMP elevating drugs
15. AP-1 function and regulation
16. UVB light induces nuclear factor -κB (NF-κB) activity independently from chromosomal DNA damage in cell-free cytosolic extracts
17. Rapid and preferential activation of the c-jun gene during the mammalian UV response
18. Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent
19. Activation of transcription factor NF-κB is suppressed by curcumin (diferuloylmethane)
20. Curcumin inhibits IL1-α and TNF-α induction of AP-1 and NF-κB DNA-binding activity in bone marrow stromal cells
21. Inhibition of cytokine gene expression by sodium salicylate in a macrophage cell line through an NF-κB-independent mechanism
22. Inhibition of NF-kappaB activation by pyrrolidine dithiocarbamate prevents In vivo expression of proinflammatory genes
23. Transcriptional up-regulation of intracellular adhesion molecule-1 in human endothelial cells by the antioxidant pyrrolidine dithiocarbamate involves the activation of activating protein-1
24. Role of oxidants and antioxidants in the induction of AP-1. NF-kappaB, and glutathione S-transferase gene expression
25. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
26. Differential spontaneous expression of mRNA for IL-4, IL-10, IL-13, IL-2 and interferon-gamma (IFN-gamma) in peripheral blood mononuclear cells (PBMC) from atopic patients
27. Regulation of epidermal cell interleukin-6 production by UV light and corticosteroids
28. IL-8 gene expression and production in human keratinocytes and their modulation by UVB
29. Ultraviolet-A induces activation of AP-1 in cultured human keratinocytes
30. UV-A-induced decrease in nuclear factor-κB activity in human keratinocytes
31. Differential regulation of IFN-gamma, IL-10 and inducible nitric oxide synthase in human T cells by cyclic AMP-dependent signal transduction pathway
32. In contrast to their murine counterparts, normal human keratinocytes and human epidermoid cell lines A431 and HaCaT fail to express IL-10 mRNA and protein
33. Pyrrolidine dithiocarbamate inhibits NF-κB mobilization and TNF production in human monocytes
34. Influence of pyrrolidine dithiocarbamate on the inflammatory response in macrophages and mouse endotoxin shock
35. The dietary pigment curcumin reduces endothelial tissue factor gene expression by inhibiting binding of AP-1 to the DNA and activation of NF-κB
36. Inhibition of tumor necrosis factor by curcumin, a phytochemical
37. Tumor necrosis factor-alpha induces expression of monocyte chemoattractant JE via fos and jun genes in clonal osteoblastic MC3T3-E1 cells
38. Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells
39. Dithiocarbamates as potent inhibitors of nuclear factor-κB activation in intact cells
40. JNK (c-Jun NH2-terminal kinase) is a target for antioxidants in T lymphocytes
41. IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3
42. Selection of optimal kappa B/Rel DNA-binding motifs: Interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation