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Volumn 35, Issue 1, 2002, Pages 28-40

Nuclear factor-κB activation: A question of life or death

Author keywords

Apoptosis; Caspases; NF B; Reactive oxygen intermediates; TNF

Indexed keywords

APOPTOSIS INDUCING FACTOR; APOPTOSIS INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR; TRANSCRIPTION FACTOR;

EID: 0037203538     PISSN: 12258687     EISSN: None     Source Type: Journal    
DOI: 10.5483/bmbrep.2002.35.1.028     Document Type: Review
Times cited : (249)

References (145)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams, J. M. and Cory, S. (1998) The Bcl-2 protein family: arbiters of cell survival. Science 281, 1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 3
    • 0030694424 scopus 로고    scopus 로고
    • Inhibition of caspase proteases by CrmA enhances the resistance of human leukemic cells to multiple chemotherapeutic agents
    • Antoku, K., Liu, Z. and Johnson, D. E. (1997) Inhibition of caspase proteases by CrmA enhances the resistance of human leukemic cells to multiple chemotherapeutic agents. Leukemia 11, 1665-1672.
    • (1997) Leukemia , vol.11 , pp. 1665-1672
    • Antoku, K.1    Liu, Z.2    Johnson, D.E.3
  • 4
    • 0035569054 scopus 로고    scopus 로고
    • Endothelial apoptosis induced by oxidative stress through activation of NF-kappaB: Antiapoptotic effect of antioxidant agents on endothelial cells
    • Aoki, M., Nata, T., Morishita, R., Matsushita, H., Nakagami, H., Yamamoto, K. Yamazaki, K., Nakabayashi, M., Ogihara, T. and Kaneda, Y. (2001) Endothelial apoptosis induced by oxidative stress through activation of NF-kappaB: antiapoptotic effect of antioxidant agents on endothelial cells. Hypertension 38, 48-55.
    • (2001) Hypertension , vol.38 , pp. 48-55
    • Aoki, M.1    Nata, T.2    Morishita, R.3    Matsushita, H.4    Nakagami, H.5    Yamamoto, K.6    Yamazaki, K.7    Nakabayashi, M.8    Ogihara, T.9    Kaneda, Y.10
  • 5
    • 0025932984 scopus 로고
    • Apoptosis: Mechanisms and roles in pathology
    • Arends, M. J. and Wyllie, A. H. (1991) Apoptosis: mechanisms and roles in pathology. Int. Rev. Exp. Pathol. 32, 223-254
    • (1991) Int. Rev. Exp. Pathol. , vol.32 , pp. 223-254
    • Arends, M.J.1    Wyllie, A.H.2
  • 6
    • 0035804222 scopus 로고    scopus 로고
    • Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells
    • Arlt, A., Grobe, O., Sieke, A., Kruse, M. L., Folsch, U. R., Schmidt, W. E. and Schafer, H. (2001) Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells. Oncogene 20, 69-76.
    • (2001) Oncogene , vol.20 , pp. 69-76
    • Arlt, A.1    Grobe, O.2    Sieke, A.3    Kruse, M.L.4    Folsch, U.R.5    Schmidt, W.E.6    Schafer, H.7
  • 7
    • 0035864344 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin
    • Arlt, A., Vorndamm, J., Breitenbroich, M., Folsch, U. R., Kalthoff, H., Schmidt, W. E. and Schafer, H. (2001) Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin. Oncogene 20, 859-868.
    • (2001) Oncogene , vol.20 , pp. 859-868
    • Arlt, A.1    Vorndamm, J.2    Breitenbroich, M.3    Folsch, U.R.4    Kalthoff, H.5    Schmidt, W.E.6    Schafer, H.7
  • 8
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi, A. and Dixit, V. M. (1998) Death receptors: signaling and modulation. Science 281, 1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 9
    • 0032563764 scopus 로고    scopus 로고
    • Relationship between IkappaBalpha constitutive expression, TNFalpha synthesis, and apoptosis in EBV-infected lymphoblastoid cells
    • Asso-Bonnet, M., Feuillard, J., Ferreira, V., Bissieres, P., Tarantino, N., Korner, M. and Raphael, M. (1998) Relationship between IkappaBalpha constitutive expression, TNFalpha synthesis, and apoptosis in EBV-infected lymphoblastoid cells. Oncogene 24, 1607-1615.
    • (1998) Oncogene , vol.24 , pp. 1607-1615
    • Asso-Bonnet, M.1    Feuillard, J.2    Ferreira, V.3    Bissieres, P.4    Tarantino, N.5    Korner, M.6    Raphael, M.7
  • 11
    • 0027332498 scopus 로고
    • The IκB proteins: Multifunctional regulators of Rel/ NF-κB trancription factors
    • Beg, A. A. and Baldwin, A. S. (1993) The IκB proteins: Multifunctional regulators of Rel/ NF-κB trancription factors. Genes Dev. 7, 2064-2070.
    • (1993) Genes Dev. , vol.7 , pp. 2064-2070
    • Beg, A.A.1    Baldwin, A.S.2
  • 12
    • 0029976817 scopus 로고    scopus 로고
    • An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
    • Beg, A. A. and Baltimore, D. (1996). An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274, 782-784.
    • (1996) Science , vol.274 , pp. 782-784
    • Beg, A.A.1    Baltimore, D.2
  • 13
    • 0032587410 scopus 로고    scopus 로고
    • Nuclear factor kappaB cooperates with c-Myc in promoting murine hepatocyte survival in a manner independent of p53 tumor suppressor function
    • Bellas, R. E. and Sonenshein G. E. (1999) Nuclear factor kappaB cooperates with c-Myc in promoting murine hepatocyte survival in a manner independent of p53 tumor suppressor function. Cell Growth & Differ. 10, 287-294.
    • (1999) Cell Growth & Differ. , vol.10 , pp. 287-294
    • Bellas, R.E.1    Sonenshein, G.E.2
  • 14
    • 0034957413 scopus 로고    scopus 로고
    • Effect of NF- kappa B inhibition on TNF-alpha-induced apoptosis and downstream pathways in cardiomyocytes
    • Bergmann, M. W., Loser, P., Dietz, R. and Harsdorf , R. (2001) Effect of NF- kappa B Inhibition on TNF-alpha-induced Apoptosis and Downstream Pathways in Cardiomyocytes. J Mol. Cell Cardiol. 33, 1223-1232.
    • (2001) J. Mol. Cell Cardiol. , vol.33 , pp. 1223-1232
    • Bergmann, M.W.1    Loser, P.2    Dietz, R.3    Harsdorf, R.4
  • 15
    • 0032698132 scopus 로고    scopus 로고
    • Insulin antiapoptotic signaling involves insulin activation of the nuclear factor kappaB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase
    • Bertrand, F., Desbois-Mouthon, C., Cadoret, A., Prunier, C., Robin, H., Capeau, J., Atfi, A. and Cherqui, G. (1999). Insulin antiapoptotic signaling involves insulin activation of the nuclear factor kappaB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase. J. Biol. Chem. 274, 30596-30602.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30596-30602
    • Bertrand, F.1    Desbois-Mouthon, C.2    Cadoret, A.3    Prunier, C.4    Robin, H.5    Capeau, J.6    Atfi, A.7    Cherqui, G.8
  • 16
    • 0032493369 scopus 로고    scopus 로고
    • Evidence for a role of NF-kappaB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor beta fusion protein
    • Besancon, F., Atfi. A., Gespach, C., Cayre, Y. E. and Bourgeade, M. F. (1998) Evidence for a role of NF-kappaB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor beta fusion protein. Proc. Natl. Acad. Sci. USA 95, 8081-8086.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8081-8086
    • Besancon, F.1    Atfi, A.2    Gespach, C.3    Cayre, Y.E.4    Bourgeade, M.F.5
  • 17
    • 0028072422 scopus 로고
    • Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes
    • Bessho, R., Matsubara, K., Kubota, M., Kuwakado, K., Hirota, H., Wakazono, Y., Lin, Y. W., Okuda, A., Kawai, M., Nishikomori, R. and Heike, T. (1994) Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes. Biochem. Pharmacol. 48, 1883-1889.
    • (1994) Biochem. Pharmacol , vol.48 , pp. 1883-1889
    • Bessho, R.1    Matsubara, K.2    Kubota, M.3    Kuwakado, K.4    Hirota, H.5    Wakazono, Y.6    Lin, Y.W.7    Okuda, A.8    Kawai, M.9    Nishikomori, R.10    Heike, T.11
  • 18
    • 0034668204 scopus 로고    scopus 로고
    • A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis
    • Beyaert, R., Heyninck, K. and Van Huffel, S. (2000) A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis. Biochem. Pharmacol. 60, 1143-1151.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 1143-1151
    • Beyaert, R.1    Heyninck, K.2    Van Huffel, S.3
  • 19
    • 0028788309 scopus 로고
    • Microfilament reorganization during apoptosis: The role of Gas2, a possible substrate for ICE-like proteases
    • Brancolini, C., Benedetti, M. and Schneider, C. (1995) Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE-like proteases. EMBO J. 14, 5179-5190.
    • (1995) EMBO J. , vol.14 , pp. 5179-5190
    • Brancolini, C.1    Benedetti, M.2    Schneider, C.3
  • 20
    • 0034669923 scopus 로고    scopus 로고
    • Identification of a role for NF-kappa B2 in the regulation of apoptosis and in maintenance of T cell-mediated immunity to Toxoplasma gondii
    • Caamano, J., Tato, C., Cai, G., Villegas, E. N., Speirs, K., Craig, L., Alexander, J. and Hunter, C. A. (2000) Identification of a role for NF-kappa B2 in the regulation of apoptosis and in maintenance of T cell-mediated immunity to Toxoplasma gondii. J. Immunol. 165, 5720-5728.
    • (2000) J. Immunol. , vol.165 , pp. 5720-5728
    • Caamano, J.1    Tato, C.2    Cai, G.3    Villegas, E.N.4    Speirs, K.5    Craig, L.6    Alexander, J.7    Hunter, C.A.8
  • 21
    • 0030614456 scopus 로고    scopus 로고
    • IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-alpha-induced apoptosis
    • Cai, Z., Korner, M., Tarantino, N. and Chouaib, S. (1997) IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-alpha-induced apoptosis. J. Biol. Chem. 272, 96-101.
    • (1997) J. Biol. Chem. , vol.272 , pp. 96-101
    • Cai, Z.1    Korner, M.2    Tarantino, N.3    Chouaib, S.4
  • 22
    • 0029890823 scopus 로고    scopus 로고
    • Apopain/CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death
    • Casciola-Rosen. L., Nicholson, D. W., Chong, T., Rowan, K. R., Thornberry, N. A., Miller, D. K. and Rosen, A. (1996) Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. J. Exp. Med. 183, 1957-1964.
    • (1996) J. Exp. Med. , vol.183 , pp. 1957-1964
    • Casciola-Rosen, L.1    Nicholson, D.W.2    Chong, T.3    Rowan, K.R.4    Thornberry, N.A.5    Miller, D.K.6    Rosen, A.7
  • 24
    • 0033596120 scopus 로고    scopus 로고
    • Regulation of DNA binding by Rel/NF-kappaB transcription factors: Structural views
    • Chen, F. E. and Ghosh, G. (1999) Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views. Oncogene 18, 6845-6852.
    • (1999) Oncogene , vol.18 , pp. 6845-6852
    • Chen, F.E.1    Ghosh, G.2
  • 25
    • 0035914417 scopus 로고    scopus 로고
    • Suppression of tumor necrosis factor-mediated apoptosis by NF-κB-independent BMP/Smad signaling
    • Chen, S., Guttridge, D., Tang, E., Shi, S., Guan, K. and Wang, C. Y. (2001) Suppression of tumor necrosis factor-mediated apoptosis by NF-κB-independent BMP/Smad signaling. J. Biol. Chem. 276, 39259-39263.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39259-39263
    • Chen, S.1    Guttridge, D.2    Tang, E.3    Shi, S.4    Guan, K.5    Wang, C.Y.6
  • 26
  • 27
    • 0030885421 scopus 로고    scopus 로고
    • Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control
    • Chu, Z. L., McKinsey, T. A., Liu, L., Gentry, J. J., Malim, M. H., and Ballard, D. W. (1997) Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control. Proc. Natl. Acad. Sci. USA 94, 10057-10062.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 10057-10062
    • Chu, Z.L.1    McKinsey, T.A.2    Liu, L.3    Gentry, J.J.4    Malim, M.H.5    Ballard, D.W.6
  • 28
    • 0028800903 scopus 로고
    • Historic apoptosis
    • Clarke, P. G. and Clarke, S. (1995) Historic apoptosis. Nature. 16, 378(6554): 230.
    • (1995) Nature , vol.378 , Issue.6554 , pp. 230
    • Clarke, P.G.1    Clarke, S.2
  • 29
    • 0027513268 scopus 로고
    • Apoptosis
    • Cohen, J. J. (1993) Apoptosis. Immunol. Today 14, 126-130.
    • (1993) Immunol. Today , vol.14 , pp. 126-130
    • Cohen, J.J.1
  • 30
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen, G. M. (1997) Caspases: the executioners of apoptosis. Biochem. J. 326, 1-16.
    • (1997) Biochem. J. , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 33
    • 0029099845 scopus 로고
    • Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B
    • Darmon, A. J., Nicholson, D. W. and Bleackley, R. C. (1995) Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 377, 446-448.
    • (1995) Nature , vol.377 , pp. 446-448
    • Darmon, A.J.1    Nicholson, D.W.2    Bleackley, R.C.3
  • 34
    • 0011068524 scopus 로고    scopus 로고
    • Signal transduction by TNF and TNF-related Ligands and their receptors
    • Darnay, B. G. and Aggarwal, B. B. (1999) Signal transduction by TNF and TNF-related Ligands and Their receptors. Ann. Rheumatic Diseases 58, S0-S11.
    • (1999) Ann. Rheumatic Diseases , vol.58
    • Darnay, B.G.1    Aggarwal, B.B.2
  • 35
    • 0032508486 scopus 로고    scopus 로고
    • Bcl-2 activates the transcription factor NF-kappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha
    • de Moissac, D., Mustapha, S., Greenberg, A. H. and Kirshenbaum, L. A. (1998) Bcl-2 activates the transcription factor NF-kappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha. J. Biol. Chem. 273, 23946-23951.
    • (1998) J. Biol. Chem. , vol.273 , pp. 23946-23951
    • De Moissac, D.1    Mustapha, S.2    Greenberg, A.H.3    Kirshenbaum, L.A.4
  • 37
    • 0033590630 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB
    • Dumont, A., Hehner, S. P., Hofmann, T G., Ueffing, M., Droge, W. and Schmitz, M. L. (1999) Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB. Oncogene 18, 747-757.
    • (1999) Oncogene , vol.18 , pp. 747-757
    • Dumont, A.1    Hehner, S.P.2    Hofmann, T.G.3    Ueffing, M.4    Droge, W.5    Schmitz, M.L.6
  • 38
    • 0033626629 scopus 로고    scopus 로고
    • IkappaB/NF-kappaB mediated cisplatin resistance in HeLa cells after low-dose gamma-irradiation is associated with altered SODD expression
    • Eichholtz-Wirth, H. and Sagan, D. (2000) IkappaB/NF-kappaB mediated cisplatin resistance in HeLa cells after low-dose gamma-irradiation is associated with altered SODD expression. Apoptosis 5, 255-263.
    • (2000) Apoptosis , vol.5 , pp. 255-263
    • Eichholtz-Wirth, H.1    Sagan, D.2
  • 39
    • 0031888955 scopus 로고    scopus 로고
    • Caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A. and Nagata, S. A. (1998) Caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391, 43-50.
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.A.6
  • 40
    • 0032055940 scopus 로고    scopus 로고
    • A20 inhibits NF-kappaB activation in endothelial cells without sensitizing to tumor necrosis factor-mediated apoptosis
    • Ferran, C., Stroka, D. M., Badrichani, A. Z., Cooper, J. T., Wrighton, C. J., Soares, M., Grey, S. T. and Bach, F. H. (1998) A20 inhibits NF-kappaB activation in endothelial cells without sensitizing to tumor necrosis factor-mediated apoptosis. Blood 91, 2249-2258.
    • (1998) Blood , vol.91 , pp. 2249-2258
    • Ferran, C.1    Stroka, D.M.2    Badrichani, A.Z.3    Cooper, J.T.4    Wrighton, C.J.5    Soares, M.6    Grey, S.T.7    Bach, F.H.8
  • 41
    • 0034667635 scopus 로고    scopus 로고
    • NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells
    • Foehr, E. D., Lin, X., O'Mahony, A., Geleziunas, R., Bradshaw, R. A. and Greene, W. C. (2000) NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells. J. Neurosci. 20, 7556-7563.
    • (2000) J. Neurosci. , vol.20 , pp. 7556-7563
    • Foehr, E.D.1    Lin, X.2    O'Mahony, A.3    Geleziunas, R.4    Bradshaw, R.A.5    Greene, W.C.6
  • 43
    • 0031897632 scopus 로고    scopus 로고
    • NF-κB and Rel proteins: Evolutionary conserved mediators of immune responses
    • Ghosh, S., May, M. J. and Kopp, E. B. (1998) NF-κB and Rel proteins: Evolutionary conserved mediators of immune responses. Annu. Rev. Immunol. 16, 225-260.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 44
    • 0344731406 scopus 로고    scopus 로고
    • Induction of apoptosis by double-stranded RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB
    • Gil, J., Alcami, J. and Esteban, M. (1999) Induction of apoptosis by double-stranded RNA-dependent protein kinase (PKR) involves the alpha subunit of eukaryotic translation initiation factor 2 and NF-kappaB. Mol. Cell. Biol. 19, 4653-4663.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4653-4663
    • Gil, J.1    Alcami, J.2    Esteban, M.3
  • 45
  • 46
    • 0033596128 scopus 로고    scopus 로고
    • Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel
    • Gilmore, T. D. (1999) Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel. Oncogene. 18, 6925-6937.
    • (1999) Oncogene , vol.18 , pp. 6925-6937
    • Gilmore, T.D.1
  • 47
    • 0034574885 scopus 로고    scopus 로고
    • Tumor necrosis factor and reactive oxygen species cooperative cytotoxicity is mediated via inhibition of NF-kappaB
    • Ginis, I., Hallenbeck, J. M., Liu, J., Spatz, M., Jaiswal, R. and Shohami, E. (2000) Tumor necrosis factor and reactive oxygen species cooperative cytotoxicity is mediated via inhibition of NF-kappaB. Mol. Med. 6, 1028-1041.
    • (2000) Mol. Med. , vol.6 , pp. 1028-1041
    • Ginis, I.1    Hallenbeck, J.M.2    Liu, J.3    Spatz, M.4    Jaiswal, R.5    Shohami, E.6
  • 48
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green, D. R. and Reed, J. C. (1998) Mitochondria and apoptosis. Science 281, 1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 49
    • 0034616946 scopus 로고    scopus 로고
    • Apoptotic pathways: Paper wraps stone blunts scissors
    • Green, D. R. (2000) Apoptotic pathways: paper wraps stone blunts scissors. Cell 102, 1-4.
    • (2000) Cell , vol.102 , pp. 1-4
    • Green, D.R.1
  • 50
    • 0032745109 scopus 로고    scopus 로고
    • A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets
    • Grey, S. T., Arvelo, M. B., Hasenkamp, W., Bach, F. H. and Ferran, C. (1999) A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets. J. Exp. Med. 190, 1135-1146.
    • (1999) J. Exp. Med. , vol.190 , pp. 1135-1146
    • Grey, S.T.1    Arvelo, M.B.2    Hasenkamp, W.3    Bach, F.H.4    Ferran, C.5
  • 51
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross, A., McDonnell, J. M. and Korsmeyer, S. J. (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13, 1899-911.
    • (1999) Genes Dev. , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 52
    • 0035903124 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kappa B-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells
    • Gupta, R. A., Polk, D. B., Krishna, U., Israel, D. A., Yan, F., DuBois, R. N. and Peek R. M. Jr. (2001) Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kappa B-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells. J. Biol. Chem. 276, 31059-31066.
    • (2001) J. Biol. Chem. , vol.276 , pp. 31059-31066
    • Gupta, R.A.1    Polk, D.B.2    Krishna, U.3    Israel, D.A.4    Yan, F.5    DuBois, R.N.6    Peek R.M., Jr.7
  • 53
    • 0032588186 scopus 로고    scopus 로고
    • NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1
    • Guttridge, D. C., Albanese, C., Reuther, J. Y., Pestell, R. G. and Baldwin, A. S. Jr. (1999) NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol. Cell. Biol. 19, 5785-5799.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5785-5799
    • Guttridge, D.C.1    Albanese, C.2    Reuther, J.Y.3    Pestell, R.G.4    Baldwin A.S., Jr.5
  • 54
    • 0035933483 scopus 로고    scopus 로고
    • Overexpression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-kappaB-independent and -dependent pathways
    • Hall, J. L., Wang, X., Van Adamson, Zhao, Y. and Gibbons, G. H. (2001) Overexpression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-kappaB-independent and -dependent pathways. Circ. Res. 88, 1247-1253.
    • (2001) Circ. Res. , vol.88 , pp. 1247-1253
    • Hall, J.L.1    Wang, X.2    Van Adamson3    Zhao, Y.4    Gibbons, G.H.5
  • 55
  • 56
    • 0029834145 scopus 로고    scopus 로고
    • Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B
    • Helenius, M., Hanninen, M., Lehtinen, S. K. and Salminen, A. (1996) Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B. Biochem. J. 318, 603-608.
    • (1996) Biochem. J. , vol.318 , pp. 603-608
    • Helenius, M.1    Hanninen, M.2    Lehtinen, S.K.3    Salminen, A.4
  • 58
    • 0033521663 scopus 로고    scopus 로고
    • An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis
    • Hettmann, T., DiDonato, J., Karin, M. and Leiden, J. M. (1996) An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis. J. Exp. Med. 189, 145-158.
    • (1996) J. Exp. Med. , vol.189 , pp. 145-158
    • Hettmann, T.1    DiDonato, J.2    Karin, M.3    Leiden, J.M.4
  • 59
    • 0032588170 scopus 로고    scopus 로고
    • NF-kappaB function in growth control: Regulation of cyclin D1 expression and G0/G1-to-S-phase transition
    • Hinz, M., Krappmann, D., Eichten, A., Heder, A., Scheidereit, C. and Strauss, M. (1999) NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol. & Cell. Biol. 19, 2690-2698.
    • (1999) Mol. & Cell. Biol. , vol.19 , pp. 2690-2698
    • Hinz, M.1    Krappmann, D.2    Eichten, A.3    Heder, A.4    Scheidereit, C.5    Strauss, M.6
  • 60
    • 0034698053 scopus 로고    scopus 로고
    • Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1
    • Hofer-Warbinek, R., Schmid, J. A., Stehlik, C., Binder, B. R., Lipp, J. and de Martin R. (2000) Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1. J. Biol. Chem. 275, 22064-22068.
    • (2000) J. Biol. Chem. , vol.275 , pp. 22064-22068
    • Hofer-Warbinek, R.1    Schmid, J.A.2    Stehlik, C.3    Binder, B.R.4    Lipp, J.5    De Martin, R.6
  • 61
    • 0033568622 scopus 로고    scopus 로고
    • TNF-alpha-induced growth suppression of CD34+ myeloid leukemic cell lines signals through TNF receptor type I and is associated with NF-kappa B activation
    • Hu, X., Tang, M., Fisher, A. B., Olashaw, N. and Zuckerman, K. S. (1999) TNF-alpha-induced growth suppression of CD34+ myeloid leukemic cell lines signals through TNF receptor type I and is associated with NF-kappa B activation. J. Immunol. 163, 3106-3115.
    • (1999) J. Immunol. , vol.163 , pp. 3106-3115
    • Hu, X.1    Tang, M.2    Fisher, A.B.3    Olashaw, N.4    Zuckerman, K.S.5
  • 62
    • 0034660614 scopus 로고    scopus 로고
    • p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression
    • Ivanov, V. N. and Ronai, Z. (2000) p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression. Oncogene 19, 3003-3012.
    • (2000) Oncogene , vol.19 , pp. 3003-3012
    • Ivanov, V.N.1    Ronai, Z.2
  • 63
    • 0035953398 scopus 로고    scopus 로고
    • Expression of zinc finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFalpha and suppression of NF-kappaB activities
    • Ivanov, V. N. Fodstad, O. and Ronai, Z. (2001) Expression of zinc finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFalpha and suppression of NF-kappaB activities. Oncogene 20, 2243-2253.
    • (2001) Oncogene , vol.20 , pp. 2243-2253
    • Ivanov, V.N.1    Fodstad, O.2    Ronai, Z.3
  • 64
    • 0038668000 scopus 로고    scopus 로고
    • Escaping cell death: Survival proteins in cancer
    • Jaattela, M. (1999) Escaping cell death: survival proteins in cancer. Exp. Cell Res. 248, 30-43.
    • (1999) Exp. Cell Res. , vol.248 , pp. 30-43
    • Jaattela, M.1
  • 65
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson, M. D., Weil, M. and Raft M. C. (1997) Programmed cell death in animal development. Cell 88, 347-354.
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raft, M.C.3
  • 66
    • 0035913158 scopus 로고    scopus 로고
    • NF-kappa B activation results in rapid inactivation of JNK in TNF alpha-treated Ewing sarcoma cells: A mechanism for the anti-apoptotic effect of NF-kappa B
    • Javelaud, D. and Besancon, F. (2001) NF-kappa B activation results in rapid inactivation of JNK in TNF alpha-treated Ewing sarcoma cells: a mechanism for the anti-apoptotic effect of NF-kappa B. Oncogene 20, 365-372.
    • (2001) Oncogene , vol.20 , pp. 365-372
    • Javelaud, D.1    Besancon, F.2
  • 67
    • 0033593655 scopus 로고    scopus 로고
    • Prevention of constitutive TNF receptor 1 signaling by silencer of death domains
    • Jiang, Y., Woronicz, J. D., Liu, W. and Goeddel, D. V. (1999) Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. Science 283, 543-546.
    • (1999) Science , vol.283 , pp. 543-546
    • Jiang, Y.1    Woronicz, J.D.2    Liu, W.3    Goeddel, D.V.4
  • 68
  • 69
    • 0034959512 scopus 로고    scopus 로고
    • TGF-alpha inhibits apoptosis of murine gastric pit cells through an NF-kappaB-dependent pathway
    • Kanai, M., Konda, Y., Nakajima, T. Izumi, Y., Takeuchi, T. and Chiba, T. (2001) TGF-alpha inhibits apoptosis of murine gastric pit cells through an NF-kappaB-dependent pathway. Gastroenterology 121, 56-67.
    • (2001) Gastroenterology , vol.121 , pp. 56-67
    • Kanai, M.1    Konda, Y.2    Nakajima, T.3    Izumi, Y.4    Takeuchi, T.5    Chiba, T.6
  • 70
    • 0033595893 scopus 로고    scopus 로고
    • How NF-κB is activated: The role of the IKK comples
    • Karin, M. (1999) How NF-κB is activated: The role of the IKK comples. Oncogene 18, 6867-6874.
    • (1999) Oncogene , vol.18 , pp. 6867-6874
    • Karin, M.1
  • 71
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
    • Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E. and Poirier, G. G. (1993) Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res. 53, 3976-3985.
    • (1993) Cancer Res. , vol.53 , pp. 3976-3985
    • Kaufmann, S.H.1    Desnoyers, S.2    Ottaviano, Y.3    Davidson, N.E.4    Poirier, G.G.5
  • 72
    • 0024470862 scopus 로고
    • Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: A cautionary note
    • Kaufmann, S. H. (1989) Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res. 49, 5870-5878.
    • (1989) Cancer Res. , vol.49 , pp. 5870-5878
    • Kaufmann, S.H.1
  • 73
    • 0033572270 scopus 로고    scopus 로고
    • Down-regulation of nuclear factor kappaB is required for p53-dependent apoptosis in X-ray-irradiated mouse lymphoma cells and thymocytes
    • Kawai, H., Yamada, Y., Tatsuka, M., Niwa, O., Yamamoto, K. and Suzuki, F. (1999) Down-regulation of nuclear factor kappaB is required for p53-dependent apoptosis in X-ray-irradiated mouse lymphoma cells and thymocytes. Cancer Res. 59, 6038-6041.
    • (1999) Cancer Res. , vol.59 , pp. 6038-6041
    • Kawai, H.1    Yamada, Y.2    Tatsuka, M.3    Niwa, O.4    Yamamoto, K.5    Suzuki, F.6
  • 74
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J. F., Wyllie, A. H. and Currie, A. R. (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 75
    • 0034663779 scopus 로고    scopus 로고
    • The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes
    • Khoshnan, A., Tindell, C., Laux, I., Bae, D., Bennett, B. and Nel, A. E. (2000) The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. J. Immunol. 165, 1743-1754.
    • (2000) J. Immunol. , vol.165 , pp. 1743-1754
    • Khoshnan, A.1    Tindell, C.2    Laux, I.3    Bae, D.4    Bennett, B.5    Nel, A.E.6
  • 76
    • 0030248272 scopus 로고    scopus 로고
    • Ceramide-induced nuclear translocation of NF-kappa B is a potential mediator of the apoptotic response to TNF-alpha in murine clonal osteoblasts
    • Kitajima, I., Soejima, Y., Takasaki, I., Beppu, H., Tokioka, T. and Maruyama, I. (1996) Ceramide-induced nuclear translocation of NF-kappa B is a potential mediator of the apoptotic response to TNF-alpha in murine clonal osteoblasts. Bone 19, 263-270.
    • (1996) Bone , vol.19 , pp. 263-270
    • Kitajima, I.1    Soejima, Y.2    Takasaki, I.3    Beppu, H.4    Tokioka, T.5    Maruyama, I.6
  • 77
    • 0033565406 scopus 로고    scopus 로고
    • Inhibition of NF-kappa B activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3
    • Kolenko, V., Bloom, T., Rayman, P., Bukowski, R., Hsi, E. and Finke J. (1999) Inhibition of NF-kappa B activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3. J. Immunol. 163, 590-598.
    • (1999) J. Immunol. , vol.163 , pp. 590-598
    • Kolenko, V.1    Bloom, T.2    Rayman, P.3    Bukowski, R.4    Hsi, E.5    Finke, J.6
  • 78
    • 0026699666 scopus 로고
    • Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements
    • Krikos, A. Laherty, C. D. and Dixit, V. M. (1992) Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements. J. Biol. Chem. 267, 17971-17976.
    • (1992) J. Biol. Chem. , vol.267 , pp. 17971-17976
    • Krikos, A.1    Laherty, C.D.2    Dixit, V.M.3
  • 79
    • 0033621839 scopus 로고    scopus 로고
    • NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis
    • Kuhnel, F., Zender, L., Paul, Y., Tietze, M. K., Trautwein, C., Manns, M. and Kubicka, S. (2000) NFkappaB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis. J. Biol. Chem. 275, 6421-6427.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6421-6427
    • Kuhnel, F.1    Zender, L.2    Paul, Y.3    Tietze, M.K.4    Trautwein, C.5    Manns, M.6    Kubicka, S.7
  • 81
    • 0000597684 scopus 로고    scopus 로고
    • PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells
    • Lee, K.Y., Chang, W., Qiu, D., Kao, P. N. and Rosen G. D. (1999) PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells. J. Biol. Chem. 274, 13451-13455.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13451-13455
    • Lee, K.Y.1    Chang, W.2    Qiu, D.3    Kao, P.N.4    Rosen, G.D.5
  • 82
    • 0033174072 scopus 로고    scopus 로고
    • Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop
    • Levkau, B., Scatena, M., Giachelli, C. M., Ross, R. and Raines, E. W. (1999) Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop. Nature Cell Biol. 1, 227-233.
    • (1999) Nature Cell Biol. , vol.1 , pp. 227-233
    • Levkau, B.1    Scatena, M.2    Giachelli, C.M.3    Ross, R.4    Raines, E.W.5
  • 83
    • 0030610080 scopus 로고    scopus 로고
    • Nuclear factor-kappaB is activated by hyperoxia but does not protect from cell death
    • Li, Y., Zhang, W., Mantell, L. L., Kazzaz, J. A., Fein, A. M. and Horowitz, S. (1997) Nuclear factor-kappaB is activated by hyperoxia but does not protect from cell death. J. Biol. Chem. 272, 20646-20649.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20646-20649
    • Li, Y.1    Zhang, W.2    Mantell, L.L.3    Kazzaz, J.A.4    Fein, A.M.5    Horowitz, S.6
  • 84
    • 0033532386 scopus 로고    scopus 로고
    • The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
    • Li, Z. W., Chu, W., Hu, Y., Delhase, M., Deerinck, T., Ellisman, M., Johnson, R. and Karin, M. (1999) The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J. Exp. Med. 189, 1839-1845.
    • (1999) J. Exp. Med. , vol.189 , pp. 1839-1845
    • Li, Z.W.1    Chu, W.2    Hu, Y.3    Delhase, M.4    Deerinck, T.5    Ellisman, M.6    Johnson, R.7    Karin, M.8
  • 85
    • 0029097316 scopus 로고
    • Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways
    • Liebermann, D. A., Hoffman, B. and Steinman, R. A. (1995) Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways. Oncogene 11, 199-210.
    • (1995) Oncogene , vol.11 , pp. 199-210
    • Liebermann, D.A.1    Hoffman, B.2    Steinman, R.A.3
  • 86
    • 0032577979 scopus 로고    scopus 로고
    • Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosis
    • Lin, K. I., DiDonato, J. A., Hoffmann, A. Hardwick, J. M. and Ratan, R.R. (1998) Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosis. J. Cell Biol. 141, 1479-1487.
    • (1998) J. Cell Biol. , vol.141 , pp. 1479-1487
    • Lin, K.I.1    DiDonato, J.A.2    Hoffmann, A.3    Hardwick, J.M.4    Ratan, R.R.5
  • 87
    • 0028785523 scopus 로고
    • Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B
    • Lin, K. I., Lee, S. H., Narayanan, R., Baraban, J. M., Hardwick, J. M. and Ratan R. R. (1995) Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B. J. Cell Biol. 131, 1149-1161.
    • (1995) J. Cell Biol. , vol.131 , pp. 1149-1161
    • Lin, K.I.1    Lee, S.H.2    Narayanan, R.3    Baraban, J.M.4    Hardwick, J.M.5    Ratan, R.R.6
  • 88
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
    • Liu, Z. G., Hsu, H., Goeddel, D. V. and Karin, M. (1996) Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell 87, 565-576.
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 89
    • 0032557458 scopus 로고    scopus 로고
    • Overexpression of Mn-superoxide dismutase suppresses TNF induced apoptosis and activation of nuclear transcription Factor-κB and activated Protein-1
    • Manna, S., Zhang, H. J., Yan T., Oberley L. W. and Aggarwal B. B. (1998) Overexpression of Mn-superoxide dismutase suppresses TNF induced apoptosis and activation of Nuclear Transcription Factor-κB and Activated Protein-1. J. Biol. Chem. 273, 13245-13254.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13245-13254
    • Manna, S.1    Zhang, H.J.2    Yan, T.3    Oberley, L.W.4    Aggarwal, B.B.5
  • 91
    • 0029610432 scopus 로고
    • Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis
    • Mashima, T., Naito, M., Fujita, N., Noguchi, K. and Tsuruo, T. (1995) Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis. Biochem. Biophys. Res. Commun. 217,1185-1192.
    • (1995) Biochem. Biophys. Res. Commun. , vol.217 , pp. 1185-1192
    • Mashima, T.1    Naito, M.2    Fujita, N.3    Noguchi, K.4    Tsuruo, T.5
  • 92
    • 0026053958 scopus 로고
    • Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t (14;18)
    • McDonnell, T. J. and Korsmeyer S. J. (1991) Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t (14;18). Nature 349, 254-256
    • (1991) Nature , vol.349 , pp. 254-256
    • McDonnell, T.J.1    Korsmeyer, S.J.2
  • 93
    • 0033522907 scopus 로고    scopus 로고
    • Identification and characterization of a novel cytokine, THANK, α TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase
    • Mukhopadhyay, A., Ni, J., Zhai, Y., Yu, G. L. and Aggarwal, B. B. (1999) Identification and characterization of a novel cytokine, THANK, α TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase. J. Biol. Chem. 274, 15978-15981.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15978-15981
    • Mukhopadhyay, A.1    Ni, J.2    Zhai, Y.3    Yu, G.L.4    Aggarwal, B.B.5
  • 94
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata, S. (1997) Apoptosis by death factor. Cell. 88, 355-365.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 95
    • 0033966324 scopus 로고    scopus 로고
    • Kainic acid-induced apoptosis in rat striatum is associated with nuclear factor-kappaB activation
    • Nakai, M., Qin, Z. H., Chen, J. F., Wang, Y. and Chase, T. N. (2000) Kainic acid-induced apoptosis in rat striatum is associated with nuclear factor-kappaB activation. J. Neurochem. 74, 647-658.
    • (2000) J. Neurochem. , vol.74 , pp. 647-658
    • Nakai, M.1    Qin, Z.H.2    Chen, J.F.3    Wang, Y.4    Chase, T.N.5
  • 96
    • 0032553419 scopus 로고    scopus 로고
    • Nuclear factor kB-independent cytoprotective pathways originating at tumor necrosis factor receptor-associated factor 2
    • Natoli, G., Costanzo, A., Guido, F., Moretti, F., Bernardo, A., Burgio, V. L., Agresti, C. and Levrero, M. (1998) Nuclear factor kB-independent cytoprotective pathways originating at tumor necrosis factor receptor-associated factor 2. J. Biol. Chem. 273, 31262-31272.
    • (1998) J. Biol. Chem. , vol.273 , pp. 31262-31272
    • Natoli, G.1    Costanzo, A.2    Guido, F.3    Moretti, F.4    Bernardo, A.5    Burgio, V.L.6    Agresti, C.7    Levrero, M.8
  • 97
    • 0026043871 scopus 로고
    • Induction of apoptosis during normal and neoplastic B-cell development in the bursa of Fabricius
    • Neiman, P. E., Thomas, S. J. and Loring, G. (1991) Induction of apoptosis during normal and neoplastic B-cell development in the bursa of Fabricius. Proc. Natl. Acad. Sci., USA 88, 5857-5861.
    • (1991) Proc. Natl. Acad. Sci., USA , vol.88 , pp. 5857-5861
    • Neiman, P.E.1    Thomas, S.J.2    Loring, G.3
  • 98
    • 0030588674 scopus 로고    scopus 로고
    • Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin
    • Okura, T., Gong, L., Kamitani, T., Wada, T., Okura, I., Wei, C. F., Chang, H.M. and Yeh, E. T. (1996) Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin. J. Immunol. 157, 4277-4281.
    • (1996) J. Immunol. , vol.157 , pp. 4277-4281
    • Okura, T.1    Gong, L.2    Kamitani, T.3    Wada, T.4    Okura, I.5    Wei, C.F.6    Chang, H.M.7    Yeh, E.T.8
  • 99
    • 0026691240 scopus 로고
    • The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity
    • Opipari, A. W. Jr., Hu, H. M., Yabkowitz, R. and Dixit, V. M. (1992) The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity. J. Biol. Chem. 267, 12424-12427.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12424-12427
    • Opipari A.W., Jr.1    Hu, H.M.2    Yabkowitz, R.3    Dixit, V.M.4
  • 100
    • 0035963273 scopus 로고    scopus 로고
    • Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells
    • Oya, M., Ohtsubo, M., Takayanagi, A., Tachibana, M., Shimizu, N. and Murai, M. (2001) Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells. Oncogene 20, 3888-3896.
    • (2001) Oncogene , vol.20 , pp. 3888-3896
    • Oya, M.1    Ohtsubo, M.2    Takayanagi, A.3    Tachibana, M.4    Shimizu, N.5    Murai, M.6
  • 102
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-κB transcription factors
    • Pahl, H. L. (1999) Activators and target genes of Rel/NF-κB transcription factors. Oncogene 18, 6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 104
    • 0033451738 scopus 로고    scopus 로고
    • TNF-Induced signaling in apoptosis
    • Rath, P. C. and Aggarwal, B. B. (1999) TNF-Induced Signaling in Apoptosis. J. Clinical Immunol. 19, 350-364.
    • (1999) J. Clinical Immunol. , vol.19 , pp. 350-364
    • Rath, P.C.1    Aggarwal, B.B.2
  • 105
    • 0032032627 scopus 로고    scopus 로고
    • CD95 (Fas)-induced caspase-mediated proteolysis of NF-kappaB
    • Ravi, R., Bedi, A., Fuchs, E. J. and Bedi, A. (1998) CD95 (Fas)-induced caspase-mediated proteolysis of NF-kappaB. Cancer Res. 58, 882-886.
    • (1998) Cancer Res. , vol.58 , pp. 882-886
    • Ravi, R.1    Bedi, A.2    Fuchs, E.J.3    Bedi, A.4
  • 106
    • 0033575220 scopus 로고    scopus 로고
    • Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB
    • Reuther, J. Y. and Baldwin, A. S. Jr. (1999) Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB. J. Biol. Chem. 274, 20664-20670.
    • (1999) J. Biol. Chem. , vol.274 , pp. 20664-20670
    • Reuther, J.Y.1    Baldwin A.S., Jr.2
  • 107
    • 0033517190 scopus 로고    scopus 로고
    • NF-kappaB is a target of AKT in anti-apoptotic PDGF signaling
    • Romashkova, J. A. and Makarov, S. S. (1999) NF-kappaB is a target of AKT in anti-apoptotic PDGF signaling [see comments]. Nature 401, 86-90.
    • (1999) Nature , vol.401 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 108
    • 0033556310 scopus 로고    scopus 로고
    • The role of c-FLIP in modulation of CD95-induced apoptosis
    • Scaffidi, C., Schmitz, I., Krammer, P. H. and Peter, M. E. (1999) The role of c-FLIP in modulation of CD95-induced apoptosis. J. Biol. Chem. 274, 1541-1548.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1541-1548
    • Scaffidi, C.1    Schmitz, I.2    Krammer, P.H.3    Peter, M.E.4
  • 110
    • 0033618395 scopus 로고    scopus 로고
    • E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities
    • Shao, R., Hu, M. C., Zhou, B. P., Lin, S. Y., Chiao, P. J., von Lindern, R. H., Spohn, B. and Hung, M. C. (1999) E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities. J. Biol. Chem. 274, 21495-21498.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21495-21498
    • Shao, R.1    Hu, M.C.2    Zhou, B.P.3    Lin, S.Y.4    Chiao, P.J.5    Von Lindern, R.H.6    Spohn, B.7    Hung, M.C.8
  • 111
    • 0031466397 scopus 로고    scopus 로고
    • Inhibition of nuclear factor-kappaB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis
    • Shao, R., Karunagaran, D., Zhou, B. P., Li, K., Lo, S. S., Deng, J., Chiao, P. and Hung, M. C. (1997) Inhibition of nuclear factor-kappaB activity is involved in E1A-mediated sensitization of radiation-induced apoptosis. J. Biol. Chem. 272, 32739-32742.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32739-32742
    • Shao, R.1    Karunagaran, D.2    Zhou, B.P.3    Li, K.4    Lo, S.S.5    Deng, J.6    Chiao, P.7    Hung, M.C.8
  • 112
    • 0033861952 scopus 로고    scopus 로고
    • Death and decoy receptors and p53-mediated apoptosis
    • Sheikh, M. S. and Fornace, A. J. Jr. (2000) Death and decoy receptors and p53-mediated apoptosis. Leukemia 14, 1509-1513.
    • (2000) Leukemia , vol.14 , pp. 1509-1513
    • Sheikh, M.S.1    Fornace A.J., Jr.2
  • 113
    • 0027948135 scopus 로고
    • Apoptosis induced in mouse hepatitis virus-infected cells by a virus specific CD8+ cytotoxic T-lymphocyte clone
    • Shibata, S., Kyuwa, S., Lee, S. K. and Goto, N. (1994) Apoptosis induced in mouse hepatitis virus-infected cells by a virus specific CD8+ cytotoxic T-lymphocyte clone. J. Virol. 68, 7540-7545.
    • (1994) J. Virol. , vol.68 , pp. 7540-7545
    • Shibata, S.1    Kyuwa, S.2    Lee, S.K.3    Goto, N.4
  • 114
    • 0029416976 scopus 로고
    • Constitutive nuclear NF-kappaB/rel DNA-binding activity of rat thymocytes is increased by stimuli that promote apoptosis, but not inhibited by pyrrolidine dithiocarbamate
    • Slater, A. F. G., Kimland, M., Jiang, S. A. and Orrenius, S. (1995) Constitutive nuclear NF-kappaB/rel DNA-binding activity of rat thymocytes is increased by stimuli that promote apoptosis, but not inhibited by pyrrolidine dithiocarbamate. Biochem. J. 312, 833-838.
    • (1995) Biochem. J. , vol.312 , pp. 833-838
    • Slater, A.F.G.1    Kimland, M.2    Jiang, S.A.3    Orrenius, S.4
  • 115
    • 0028353492 scopus 로고
    • The TNF receptor superfamily of cellular and viral proteins: Activation, co-stimulation, and death
    • Smith, C. A., Farrah, T. and Goodwin, R. G. (1994) The TNF receptor superfamily of cellular and viral proteins: activation, co-stimulation, and death. Cell 76, 959-962.
    • (1994) Cell , vol.76 , pp. 959-962
    • Smith, C.A.1    Farrah, T.2    Goodwin, R.G.3
  • 117
    • 0033231188 scopus 로고    scopus 로고
    • Modulation of cellular apoptotic potential: Contributions to oncogenesis
    • Stambolic, V., Mak, T. W. and Woodgett, J. R. (1999) Modulation of cellular apoptotic potential: contributions to oncogenesis. Oncogene 18, 6094-6103.
    • (1999) Oncogene , vol.18 , pp. 6094-6103
    • Stambolic, V.1    Mak, T.W.2    Woodgett, J.R.3
  • 118
    • 0035348486 scopus 로고    scopus 로고
    • Aspirin-induced activation of the NF-kappaB signaling pathway: A novel mechanism for aspirin-mediated apoptosis in colon cancer cells
    • Stark, L. A., Din, F. V., Zwacka, R. M. and Dunlop, M. G. (2001) Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells. FASEB J. 15, 1273-1275.
    • (2001) FASEB J. , vol.15 , pp. 1273-1275
    • Stark, L.A.1    Din, F.V.2    Zwacka, R.M.3    Dunlop, M.G.4
  • 119
    • 0032490670 scopus 로고    scopus 로고
    • Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis
    • Stehlik, C., de Martin, R., Kumabashiri, I., Schmid, J. A., Binder, B. R. and Lipp, J. (1998) Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis. J. Exp. Med. 188, 211-216.
    • (1998) J. Exp. Med. , vol.188 , pp. 211-216
    • Stehlik, C.1    De Martin, R.2    Kumabashiri, I.3    Schmid, J.A.4    Binder, B.R.5    Lipp, J.6
  • 120
    • 0033538450 scopus 로고    scopus 로고
    • Selective sensitization to tumor necrosis factor-alpha-induced apoptosis by blockade of NF-kappaB in primary glomerular mesangial cells
    • Sugiyama, H., Savill, J. S., Kitamura, M., Zhao, L. and Stylianou, E. (1999) Selective sensitization to tumor necrosis factor-alpha-induced apoptosis by blockade of NF-kappaB in primary glomerular mesangial cells. J. Biol. Chem. 274, 19532-19537.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19532-19537
    • Sugiyama, H.1    Savill, J.S.2    Kitamura, M.3    Zhao, L.4    Stylianou, E.5
  • 121
    • 0032504575 scopus 로고    scopus 로고
    • Mitochondria as regulators of apoptosis: Doubt no more
    • Susin, S. A., Zamzami, N. and Kroemer, G. (1998) Mitochondria as regulators of apoptosis: doubt no more. Biochim. Biophys. Acta 1366, 151-165.
    • (1998) Biochim. Biophys. Acta , vol.1366 , pp. 151-165
    • Susin, S.A.1    Zamzami, N.2    Kroemer, G.3
  • 122
    • 0035896601 scopus 로고    scopus 로고
    • Roles of NF-kappaB and 26 S proteasome in apoptotic cell death induced by topoisomerase I and II poisons in human nonsmall cell lung carcinoma
    • Tabata, M., Tabata, R., Grabowski, D. R., Bukowski, R. M., Ganapathi, M. K. and Ganapathi, R. (2001) Roles of NF-kappaB and 26 S proteasome in apoptotic cell death induced by topoisomerase I and II poisons in human nonsmall cell lung carcinoma. J. Biol. Chem. 276, 8029-8036.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8029-8036
    • Tabata, M.1    Tabata, R.2    Grabowski, D.R.3    Bukowski, R.M.4    Ganapathi, M.K.5    Ganapathi, R.6
  • 124
    • 0033233481 scopus 로고    scopus 로고
    • Apoptosis in Ca2+ reperfusion injury of cultured astrocytes: Roles of reactive oxygen species and NF-kappaB activation
    • Takuma, K., Lee, E. Kidawara, M., Mori, K., Kimura., Y., Baba, A. and Matsuda, T. (1999) Apoptosis in Ca2+ reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF-kappaB activation. Eur. J. Neurosci. 11, 4204-4212.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 4204-4212
    • Takuma, K.1    Lee, E.2    Kidawara, M.3    Mori, K.4    Kimura, Y.5    Baba, A.6    Matsuda, T.7
  • 125
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C. B. (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 129
    • 0032727865 scopus 로고    scopus 로고
    • Activation of AP-1 and nuclear factor-kappaB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes
    • Vollgraf, U., Wegner, M. and Richter-Landsberg, C. (1999) Activation of AP-1 and nuclear factor-kappaB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes. J. Neurochem. 73, 2501-2509.
    • (1999) J. Neurochem. , vol.73 , pp. 2501-2509
    • Vollgraf, U.1    Wegner, M.2    Richter-Landsberg, C.3
  • 130
    • 0021321027 scopus 로고
    • Preparations of lymphotoxin induce resistance to their own cytotoxic effect
    • Wallach, D. (1984) Preparations of lymphotoxin induce resistance to their own cytotoxic effect. J. Immunol. 132, 2464-2469.
    • (1984) J. Immunol. , vol.132 , pp. 2464-2469
    • Wallach, D.1
  • 132
    • 0032905030 scopus 로고    scopus 로고
    • Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB
    • Wang, C. Y., Cusack, J. C. Jr., Liu, R. and Baldwin, A. S. Jr. (1999) Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nature Med. 5, 412-417.
    • (1999) Nature Med. , vol.5 , pp. 412-417
    • Wang, C.Y.1    Cusack J.C., Jr.2    Liu, R.3    Baldwin A.S., Jr.4
  • 133
    • 0029858387 scopus 로고    scopus 로고
    • TNF-and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • Wang, C. Y., Mayo, M. W. and Baldwin, A. S. Jr. (1996) TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science 274, 784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin A.S., Jr.3
  • 134
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang, C. Y., Mayo, M. W., Korneluk, R. G., Goeddel, D. V. and Baldwin, A. S. Jr. (1998) NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281, 1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin A.S., Jr.5
  • 136
    • 0032549670 scopus 로고    scopus 로고
    • Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals
    • Widmann, C., Gibson, S. and Johnson, G. L. (1998) Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals. J. Biol. Chem. 273, 7141-7147.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7141-7147
    • Widmann, C.1    Gibson, S.2    Johnson, G.L.3
  • 137
    • 0030042598 scopus 로고    scopus 로고
    • Regulation of the cell cycle machinery by oncogenic ras
    • Winston, J. T., Coats, S. R., Wang, Y. Z. and Pledger, W. J. (1996) Regulation of the cell cycle machinery by oncogenic ras. Oncogene 12, 127-134.
    • (1996) Oncogene , vol.12 , pp. 127-134
    • Winston, J.T.1    Coats, S.R.2    Wang, Y.Z.3    Pledger, W.J.4
  • 139
    • 0032162228 scopus 로고    scopus 로고
    • TAFII105 mediates activation of anti-apoptotic genes by NF-kappaB
    • Yamit-Hezi, A. and Dikstein, R. (1998) TAFII105 mediates activation of anti-apoptotic genes by NF-kappaB. EMBO J. 17, 5161-5169.
    • (1998) EMBO J. , vol.17 , pp. 5161-5169
    • Yamit-Hezi, A.1    Dikstein, R.2
  • 140
    • 0035957951 scopus 로고    scopus 로고
    • Interferon alpha /beta promotes cell survival by activating nuclear factor kappa B through phosphatidylinositol 3-kinase and Akt
    • Yang, C, H., Murti, A., Pfeffer, S. R., Kim, J. G., Donner, D. B. and Pfeffer LM. (2001) Interferon alpha /beta promotes cell survival by activating nuclear factor kappa B through phosphatidylinositol 3-kinase and Akt. J. Biol. Chem. 276, 13756-13761.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13756-13761
    • Yang, C.H.1    Murti, A.2    Pfeffer, S.R.3    Kim, J.G.4    Donner, D.B.5    Pfeffer, L.M.6
  • 141
    • 0030707537 scopus 로고    scopus 로고
    • ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein
    • You, M., Ku, P. T., Hrdlickova, R. and Bose, H. R. Jr. (1997) ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein. Mol. Cell Biol. 17, 7328-7341.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 7328-7341
    • You, M.1    Ku, P.T.2    Hrdlickova, R.3    Bose H.R., Jr.4
  • 142
    • 0032478822 scopus 로고    scopus 로고
    • MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner
    • Zechner, D., Craig, R., Hanford, D. S., McDonough, P. M., Sabbadini, R. A. and Glembotski, C. C. (1998) MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner. J. Biol. Chem. 273, 8232-8239.
    • (1998) J. Biol. Chem. , vol.273 , pp. 8232-8239
    • Zechner, D.1    Craig, R.2    Hanford, D.S.3    McDonough, P.M.4    Sabbadini, R.A.5    Glembotski, C.C.6
  • 143
    • 0033201450 scopus 로고    scopus 로고
    • NF-kappaB activation is required for human endothelial survival during exposure to tumor necrosis factor-alpha but not to interleukin-1beta or lipopolysaccharide
    • Zen, K., Karsan, A., Stempien-Otero, A., Yee, E., Tupper, J., Li, X., Eunson, T., Kay, M. A. Wilson, C. B., Winn, R. K. and Harlan, J. M. (1999) NF-kappaB activation is required for human endothelial survival during exposure to tumor necrosis factor-alpha but not to interleukin-1beta or lipopolysaccharide. J. Biol. Chem. 274, 28808-28815.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28808-28815
    • Zen, K.1    Karsan, A.2    Stempien-Otero, A.3    Yee, E.4    Tupper, J.5    Li, X.6    Eunson, T.7    Kay, M.A.8    Wilson, C.B.9    Winn, R.K.10    Harlan, J.M.11
  • 144
    • 0030798564 scopus 로고    scopus 로고
    • v-Rel prevents apoptosis in transformed lymphoid cells and blocks TNFalpha-induced cell death
    • Zong, W. X., Farrell, M., Bash, J. and Gelinas, C. (1997) v-Rel prevents apoptosis in transformed lymphoid cells and blocks TNFalpha-induced cell death. Oncogene 15, 971-980.
    • (1997) Oncogene , vol.15 , pp. 971-980
    • Zong, W.X.1    Farrell, M.2    Bash, J.3    Gelinas, C.4
  • 145
    • 0033558215 scopus 로고    scopus 로고
    • The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis
    • Zong, W. X., Edelstein, L. C., Chen, C., Bash, J. and Gelinas, C. (1999) The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis. Genes & Dev. 13, 382-387.
    • (1999) Genes & Dev. , vol.13 , pp. 382-387
    • Zong, W.X.1    Edelstein, L.C.2    Chen, C.3    Bash, J.4    Gelinas, C.5


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