Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells

Pharmaceutical Research

Volumn 15, Issue 8, 1998, Pages 1160-1167

  Makhey, Vijaya D ^a   Guo, Ailan ^a   Norris, Daniel A ^a   Hu, Peidi ^a   Yan, Jiansheng ^a   Sinko, Patrick J ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Caco 2 cells; Colon; Drug efflux; Etoposide; Ileum; Intestinal transport kinetics; Jejunum; Verapamil hydrochloride; Vinblastine sulphate

Indexed keywords

ETOPOSIDE; VERAPAMIL; VINBLASTINE;

ANIMAL CELL; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PENETRATION; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTESTINE BRUSH BORDER; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; RAT; TEMPERATURE DEPENDENCE; TRANSPORT KINETICS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CACO-2 CELLS; COLON; ETOPOSIDE; HUMANS; ILEUM; INTESTINES; JEJUNUM; PROTONS; RATS; SODIUM; TEMPERATURE; VERAPAMIL; VINBLASTINE;

EID: 0031719032     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011971303880     Document Type: Article

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