Contribution of the murine mdr1a P-glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption

Hepatology

Volumn 27, Issue 4, 1998, Pages 1056-1063

  Smit, Johan W ^a,b   Schinkel, Alfred H ^b   Müller, Michael ^c   Weert, Betty ^a   Meijer, Dirk K F ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AZIDOPROCAINAMIDE METHIODIDE; AZOPENTYLDEOXYAJMALINIUM; CATION; GLYCOPROTEIN P; TRIBUTYLMETHYLAMMONIUM; UNCLASSIFIED DRUG; VECURONIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BILIARY EXCRETION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG URINE LEVEL; GENE DISRUPTION; INTESTINE; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BILE; BIOLOGICAL AVAILABILITY; INTESTINES; LIVER; MALE; MICE; MICE, KNOCKOUT; P-GLYCOPROTEIN; VECURONIUM BROMIDE;

EID: 0031921312     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510270422     Document Type: Article

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