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Chemico-Biological Interactions

Volumn 134, Issue 3, 2001, Pages 283-289

Pregnane X receptor: Molecular basis for species differences in CYP3A induction by xenobiotics

(1) LeCluyse, Edward L a

a UNIVERSITY OF NORTH CAROLINA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

16ALPHA CYANOPREGNENOLONE; CELL DNA; CELL NUCLEUS RECEPTOR; CYTOCHROME P450 3A; PREGNANE X RECEPTOR; RIFAMPICIN; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ARTICLE; BINDING SITE; DNA RESPONSIVE ELEMENT; ENZYME INDUCTION; GENE CONTROL; GENE EXPRESSION; HUMAN; NONHUMAN; PROMOTER REGION; PROTEIN DNA BINDING; RECEPTOR UPREGULATION; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; TRANSCRIPTION REGULATION; XENOBIOTIC METABOLISM;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MICE; OXIDOREDUCTASES, N-DEMETHYLATING; PREGNENOLONE CARBONITRILE; RABBITS; RATS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RIFAMPIN; SPECIES SPECIFICITY; XENOBIOTICS;

ORYCTOLAGUS CUNICULUS; RODENTIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0035897713 PISSN: 00092797 EISSN: None Source Type: Journal
DOI: 10.1016/S0009-2797(01)00163-6 Document Type: Article

Times cited : (173)

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