Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein

Journal of Biological Chemistry

Volumn 271, Issue 4, 1996, Pages 1877-1883

  Müller, Marianna ^a   Bakos, Éva ^b   Welker, Ervin ^a,b   Váradi, András ^b   Germann, Ursula A ^c,e   Gottesman, Michael M ^c   Morse, Brian S ^d   Roninson, Igor B ^d   Sarkadi, Balázs ^a  

^a National Institute of Haematology and Blood Transfusion Budapest   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^e VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE DERIVATIVE; ADENOSINE TRIPHOSPHATE MAGNESIUM; COLCHICINE; ETOPOSIDE; GLYCOPROTEIN P; LYSINE; METHIONINE; MUTANT PROTEIN; VERAPAMIL; VINBLASTINE; VINCRISTINE;

AMINO ACID SUBSTITUTION; ARTICLE; BACULOVIRUS; ENZYME ACTIVATION; INSECT; MULTIDRUG RESISTANCE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; VIRUS RECOMBINANT;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AFFINITY LABELS; ANIMALS; BASE SEQUENCE; CELL MEMBRANE; DNA PRIMERS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; P-GLYCOPROTEIN; SPODOPTERA; STRUCTURE-ACTIVITY RELATIONSHIP; VANADATES;

INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0030026629     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.4.1877     Document Type: Article

References (40)

1. Al-Shawi, M. K, and Senior, A. E (1993) J. Biol. Chem. 268, 4197-4206
2. Al-Shawi, M K., Urbatsch, I. L., and Senior, A. E. (1994) J. Biol Chem. 269, 8986-8992
3. Ambudkar, S. V., Lelong, I. H., Zhang, J , Cardarelli, C. O., Gottesman, M M., and Pastan, I. (1992) Proc Natl. Acad. Sci. U. S. A. 89, 8472-8476
4. Azzaria, M., Schurr, E , and Gros, P. (1989) Mol. Cell Biol 9, 5289-5297
5. Berkower, C., and Michaelis, S. (1991) EMBO J. 10, 3777-3785
6. Bibi, B., Gros, P , and Kaback, H. R. (1993) Proc. Natl Acad. Sci U. S. A. 90, 9209-9213
7. Bruggemann, E. P., Currier, S. J., Gottesman, M. M., and Pastan, I. (1992) J Biol Chem. 267, 21020-21026
8. Cardarelli, C. O., Aksentijevich, I , Pastan, I , and Gottesman, M. M. (1995) Cancer Res. 55, 1086-1091
9. Choi, K., Chen, C., Kriegler, M , and Roninaon, I. B. (1988) Cell 53, 519-529
10. Cornwell, M. M., Tsuruo, T., Gottesman, M. M., and Pastan, I. (1987) FASEB J. 1, 51-54
11. Currier, S. J., Kane, S. E., Willingham, M. C , Cardarelk, C. O., Pastan, I., and Gottesman, M. M. (1992) J Biol. Chem. 267, 25153-25159
12. Doige, C. A., Yu, X., and Sharom, F. J. (1992) Biochim Biophys. Acta 1109, 149-160
13. Doige, C A., Yu, X., and Sharom, F. J. (1993) Biochim. Biophys. Acta 1146, 65-72
14. Endicott, J. A., and Ling, V. (1989) Annu. Rev. Biochem. 58, 137-171
15. Germann, U. A., Willingham, M. C., Pastan, I., and Gottesman, M M. (1990) Biochemistry 29, 2295-2303
16. Gottesman, M. M., and Pastan, I. (1993) Annu. Rev. Biochem 62, 385-427
17. Greenberger, L M. (1993) J. Biol. Chem. 268, 11417-11425
18. Greenberger, L. M., Williams, S. S., and Horwitz, S. B. (1987) J. Biol Chem. 262, 13685-13689
19. Higgins, C. F. (1992) Annu. Rev. Cell Biol. 8, 67-113
20. Holló, Zs., Homolya, L., Davis, C. W., and Sarkadi, B. (1994) Biochim. Biophys. Acta 1191, 384-388
21. Homolya, L., Holló, Zs., Germann, U. A., Pastan, I., Gottesman, M. M., and Sarkadi, B. (1993) J. Biol. Chem. 268, 21493-21496
22. Kioka, N., Tsubota, J., Kakehi, Y., Komano, T., Gottesman, M. M., Pastan, I., and Ueda, K. (1989) Biophys. Biochem. Res. Commun. 162, 224-231
23. Loo, T. W, and Clarke, D. M. (1994a) J. Biol. Chem. 269, 7243-7248
24. Loo, T. W., and Clarke, D. M. (1994b) J. Biol. Chem 269, 7750-7755
25. Neyfakh, A. A (1988) Exp. Cell Res 174, 168-176
26. O'Reilly, D. R., Miller, L. K., and Luckow, V. A. (1992) Baculovirus Expression Vectors, A Laboratory Manual, pp. 216-229, W. H. Freeman and Co , New York
27. Parsonage D., Al-Shawi, M. K., and Senior, A. E (1988) J. Biol. Chem 263, 4740-4744
28. Rao, U. S (1995) J. Biol. Chem. 270, 6686-6690
29. Safa, A. E., Stern, R. K., Choi, K., Agresti, M., Tamai, I., Mehta, N. D., and Roninson, I. B. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 7225-7229
30. Sarkadi, B., Price, E M., Boucher, R. C , Germann, U. A., and Scarborough, G A. (1992) J. Biol. Chem. 267, 4854-4858
31. Sarkadi, B., Muller, M., Homolya, L , Holló, Zs., Seprôdi, J., Germann, U. A., Gottesman, M. M., Price, E. M., and Boucher, R. C. (1994) FASEB J. 8, 766-770
32. Schinkel, A. H , Kemp, S , Dollé, M., Rudenko, G , and Wagenaar, E. (1993) J. Biol. Chem 268, 7474-7481
33. Shapiro, A. B., and Ling, V. (1994) J. Biol. Chem 269, 3745-3754
34. Sharma, R. C., Inoue, S., Roitelman, J., Schimke, R., and Simoni, R. D. (1992) J. Biol. Chem. 267, 5731-5734
35. Sharom, F J., Yu, X., and Doige, C. A. (1993) J. Biol Chem. 268, 24197-24202
36. Shimabuku, A. M , Nishimoto, T., Ueda, K., and Komano, T. (1992) J. Chem. 267, 4308-4311
37. Tanaka, S., Currier, S. J., Bruggemann, E. P., Germann, U. A., Pastan, I., and Gottesman, M. M (1990) Biophys Biochem Res. Commun. 166, 180-186
38. Urbatsch, I. L, Al-Shawi, M. K., and Senior, A. E. (1994) Biochemistry 33, 7069-7076
39. Walker, J. E., Saraste, M., Runswick, M. J., and Gay, N. J. (1982) EMBO J. 1, 945-951
40. Zhang, L., Sachs, W., Fine, R. L., and Casey, P. J. (1994) J. Biol. Chem. 269, 15973-15976