Increased drug delivery to the brain by P-glycoprotein inhibition

Clinical Pharmacology and Therapeutics

Volumn 68, Issue 3, 2000, Pages 231-237

  Sadeque, Abu J M ^a   Wandel, Christoph ^a   He, Hauibing ^a   Shah, Selina ^a   Wood, Alastair J J ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE KINASE; CARBON DIOXIDE; GLYCOPROTEIN P; KETOCONAZOLE; LOPERAMIDE; OPIATE AGONIST; PLACEBO; QUINIDINE; VERAPAMIL;

ADULT; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIARRHEA; DOSE RESPONSE; DRUG METABOLISM; DRUG POTENTIATION; DRUG SAFETY; HUMAN; HUMAN EXPERIMENT; MALE; MEMBRANE TRANSPORT; NORMAL HUMAN; PRIORITY JOURNAL; RESPIRATION DEPRESSION;

ADRENERGIC ALPHA-ANTAGONISTS; ADULT; ANTIDIARRHEALS; BRAIN; CARBON DIOXIDE; DOUBLE-BLIND METHOD; DRUG INTERACTIONS; HUMANS; LOPERAMIDE; MALE; P-GLYCOPROTEIN; QUINIDINE; RESPIRATION;

EID: 0033833430     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1067/mcp.2000.109156     Document Type: Article

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