Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice

Journal of Pharmaceutical Sciences

Volumn 88, Issue 12, 1999, Pages 1281-1287

  Kawahara, Masami ^a   Sakata, Atsushi ^b   Miyashita, Toshiaki ^b   Tamai, Ikumi ^b   Tsuji, Akira ^b  

^a KANAZAWA UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIN; GENE PRODUCT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CLEARANCE; DRUG TISSUE LEVEL; GENE DISRUPTION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY CLEARANCE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PARTITION COEFFICIENT; PHARMACOKINETICS; PLASMA PROTEIN BINDING;

EID: 0032705762     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js9901763     Document Type: Article

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