The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

Nature Medicine

Volumn 7, Issue 5, 2001, Pages 584-590

  Synold, Timothy W ^a   Dussault, Isabelle ^a   Forman, Barry Marc ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; DOCETAXEL; GLYCOPROTEIN P; PACLITAXEL; STEROID RECEPTOR; TRABECTEDIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG CLEARANCE; DRUG EFFECT; DRUG EXCRETION; DRUG METABOLISM; DRUG TRANSPORT; ENZYME INACTIVATION; GENE TARGETING; METABOLIC INHIBITION; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ARYL HYDROCARBON HYDROXYLASES; CELL LINE; CYTOCHROME P-450 ENZYME SYSTEM; DIOXOLES; GENE EXPRESSION REGULATION; HUMANS; ISOQUINOLINES; P-GLYCOPROTEIN; PACLITAXEL; RECEPTORS, STEROID; STEROID 16-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES; TAXOIDS; TETRAHYDROISOQUINOLINES;

EID: 0035038919     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/87912     Document Type: Article

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