Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: In vitro-in vivo correlation

British Journal of Pharmacology

Volumn 118, Issue 7, 1996, Pages 1841-1847

  Fricker, G ^a   Drewe, J ^b   Huwyler, J ^b   Gutmann, H ^b   Beglinger, C ^b  

^a Inst Pharmaceut and Biopharmacy   (Germany)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Caco 2 cells; Cyclosporin A; Intestinal absorption; Intubation study; Local administration; P glycoprotein

Indexed keywords

CYCLOSPORIN A; DAUNORUBICIN; GLYCOPROTEIN P; MESSENGER RNA; MONOCLONAL ANTIBODY; VALSPODAR; VINBLASTINE;

ADULT; ANIMAL CELL; AREA UNDER THE CURVE; ARTICLE; CALCULATION; CLINICAL TRIAL; COLON; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIFFUSION; DOSE RESPONSE; DRUG ABSORPTION; DRUG TRANSPORT; DRUG UPTAKE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; ILEUM; IMMUNOBLOTTING; INTESTINE ABSORPTION; INTRAGASTRIC DRUG ADMINISTRATION; INTUBATION; JEJUNUM; MALE; MOUSE; NONHUMAN; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH; TEMPERATURE SENSITIVITY;

EID: 0029986277     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15612.x     Document Type: Article

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