-
1
-
-
0029786432
-
Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin
-
Fromm, M.F., Busse, D., Kroemer, H.K., and Eichelbaum, M. 1996. Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin. Hepatology. 24:796-801.
-
(1996)
Hepatology
, vol.24
, pp. 796-801
-
-
Fromm, M.F.1
Busse, D.2
Kroemer, H.K.3
Eichelbaum, M.4
-
2
-
-
0028054999
-
Extrahepatic metabolism of drugs in humans
-
Krishna, D.R., and Klotz, U. 1994. Extrahepatic metabolism of drugs in humans. Clin. Pharmacokinet. 26:144-160.
-
(1994)
Clin. Pharmacokinet.
, vol.26
, pp. 144-160
-
-
Krishna, D.R.1
Klotz, U.2
-
3
-
-
0021247103
-
Digoxinrifampin interaction
-
Gault, H., Longerich, L., Dawe, M., and Fine, A. 1984. Digoxinrifampin interaction. Clin. Pharmacol. Ther. 35:750-754.
-
(1984)
Clin. Pharmacol. Ther.
, vol.35
, pp. 750-754
-
-
Gault, H.1
Longerich, L.2
Dawe, M.3
Fine, A.4
-
4
-
-
84943984843
-
Rifampin and digoxin: Possible drug interaction in a dialysis patient
-
Novi, C., et al. 1980. Rifampin and digoxin: possible drug interaction in a dialysis patient. JAMA. 244:2521-2522.
-
(1980)
JAMA
, vol.244
, pp. 2521-2522
-
-
Novi, C.1
-
5
-
-
0026096151
-
Pharmacokinetics of digoxin and main metabolites/ derivatives in healthy humans
-
Hinderling, P.H., and Hartmann, D. 1991 Pharmacokinetics of digoxin and main metabolites/ derivatives in healthy humans. Ther. Drug Monit. 13:381-401.
-
(1991)
Ther. Drug Monit.
, vol.13
, pp. 381-401
-
-
Hinderling, P.H.1
Hartmann, D.2
-
6
-
-
0025917937
-
Metabolism of digoxin, digoxigenin, digitoxosides and digoxigenin in human hepatocytes and liver microsomes
-
Lacarelle, B., et al. 1991. Metabolism of digoxin, digoxigenin, digitoxosides and digoxigenin in human hepatocytes and liver microsomes. Fundam. Clin. Pharmacol. 5:567-582.
-
(1991)
Fundam. Clin. Pharmacol.
, vol.5
, pp. 567-582
-
-
Lacarelle, B.1
-
7
-
-
0027311241
-
Energy-dependent transport of digoxin across renal tubular cell monolayers (LLC-PK1)
-
Ito, S., Koren, G., and Harper, P.A. 1992. Energy-dependent transport of digoxin across renal tubular cell monolayers (LLC-PK1). Can. J. Physiol. Pharmacol. 71:40-47.
-
(1992)
Can. J. Physiol. Pharmacol.
, vol.71
, pp. 40-47
-
-
Ito, S.1
Koren, G.2
Harper, P.A.3
-
8
-
-
0010608710
-
P-glycoprotein-mediated renal tubular secretion of digoxin: The toxicological significance of the urine-blood barrier model
-
Ito, S., Woodland, C., Harper, P.A., and Koren, G. 1993. P-glycoprotein-mediated renal tubular secretion of digoxin: the toxicological significance of the urine-blood barrier model. Life Sci. 53:PL25-PL31.
-
(1993)
Life Sci.
, vol.53
-
-
Ito, S.1
Woodland, C.2
Harper, P.A.3
Koren, G.4
-
9
-
-
0027102401
-
The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin
-
de Lannoy, I.A.M., and Silverman, M. 1992. The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin. Biochem. Biophys. Res. Commun. 189:551-557.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.189
, pp. 551-557
-
-
De Lannoy, I.A.M.1
Silverman, M.2
-
10
-
-
0028825399
-
Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
-
Schinkel, A.H., Wagenaar, E., van Deemter, L., Mol, C.A.A.M., and Borst, P. 1995. Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J. Clin. Invest. 96:1698-1705.
-
(1995)
J. Clin. Invest.
, vol.96
, pp. 1698-1705
-
-
Schinkel, A.H.1
Wagenaar, E.2
Van Deemter, L.3
Mol, C.A.A.M.4
Borst, P.5
-
11
-
-
0027345980
-
Structure and function of P-glycoprotein in normal liver and small intestine
-
Gatmaitan, Z.C., and Arias, I.M. 1993. Structure and function of P-glycoprotein in normal liver and small intestine. Adv. Pharmacol. 24:77-97.
-
(1993)
Adv. Pharmacol.
, vol.24
, pp. 77-97
-
-
Gatmaitan, Z.C.1
Arias, I.M.2
-
12
-
-
0033514320
-
Inhibition of P-glycoprotein-mediated drug transport
-
Fromm, M.F., Kim, R.B., Stein, C.M., Wilkinson, G.R., and Roden, D.M. 1998. Inhibition of P-glycoprotein-mediated drug transport. Circulation. 99:552-557.
-
(1998)
Circulation
, vol.99
, pp. 552-557
-
-
Fromm, M.F.1
Kim, R.B.2
Stein, C.M.3
Wilkinson, G.R.4
Roden, D.M.5
-
13
-
-
0032518290
-
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
-
Kim, R.B., et al. 1997. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J. Clin. Invest. 101:289-294.
-
(1997)
J. Clin. Invest.
, vol.101
, pp. 289-294
-
-
Kim, R.B.1
-
14
-
-
0029860174
-
Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein
-
Mayer, U., et al. 1996. Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein. Br J. Pharmacol. 119:1038-1044.
-
(1996)
Br J. Pharmacol.
, vol.119
, pp. 1038-1044
-
-
Mayer, U.1
-
15
-
-
0025071180
-
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues
-
Cordon-Cardo, C., et al. 1990. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J. Histochem. Cytochem. 38:1277-1287.
-
(1990)
J. Histochem. Cytochem.
, vol.38
, pp. 1277-1287
-
-
Cordon-Cardo, C.1
-
16
-
-
0023447098
-
Cellular localization of the multidrug resistance gene product in normal human tissues
-
Thiebaut, F., et al. 1987. Cellular localization of the multidrug resistance gene product in normal human tissues. Proc. Natl. Acad. Sci. USA. 84:7735-7738.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
-
17
-
-
0029800447
-
Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier
-
Terao, T., Hisanaga, E., Sai, Y., Tamai, I., and Tsuji, A. 1996. Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier. J. Pharm. Pharmacol. 48:1083-1089.
-
(1996)
J. Pharm. Pharmacol.
, vol.48
, pp. 1083-1089
-
-
Terao, T.1
Hisanaga, E.2
Sai, Y.3
Tamai, I.4
Tsuji, A.5
-
18
-
-
0030781139
-
Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833
-
Mayer, U., et al. 1997. Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833. J. Clin. Invest. 100:2430-2436.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2430-2436
-
-
Mayer, U.1
-
19
-
-
0030059953
-
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells
-
Schuetz, E.G., Beck, W.T., and Schuetz, J.D. 1996. Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Mol. Pharmacol. 49:311-318.
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 311-318
-
-
Schuetz, E.G.1
Beck, W.T.2
Schuetz, J.D.3
-
20
-
-
0022998708
-
Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genomic polymorphism in oxidative drug metabolism
-
Guengerich, F.P., et al. 1986. Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genomic polymorphism in oxidative drug metabolism. J. Biol. Chem. 261:5051-5060.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 5051-5060
-
-
Guengerich, F.P.1
-
21
-
-
0019414144
-
The use of anti-avidin antibody and avidin-biotin-complex in immunoperoxidase techniques
-
Hsu, S.M., Raine, L., and Fanger, H. 1981. The use of anti-avidin antibody and avidin-biotin-complex in immunoperoxidase techniques. Am. J. Clin. Pathol. 75:816-821.
-
(1981)
Am. J. Clin. Pathol.
, vol.75
, pp. 816-821
-
-
Hsu, S.M.1
Raine, L.2
Fanger, H.3
-
22
-
-
0027236953
-
Differential expression of drug metabolizing enzymes in primary and secondary liver neoplasm: Immunohistochemical characterization of cytochrome P 450 3A and glutathione-S-transferase
-
Fritz, P., Behrle, E., Beaune, P., Eichelbaum, M., and Kroemer, H.K. 1993. Differential expression of drug metabolizing enzymes in primary and secondary liver neoplasm: immunohistochemical characterization of cytochrome P 450 3A and glutathione-S-transferase. Histochemistry. 99:443-451.
-
(1993)
Histochemistry
, vol.99
, pp. 443-451
-
-
Fritz, P.1
Behrle, E.2
Beaune, P.3
Eichelbaum, M.4
Kroemer, H.K.5
-
23
-
-
0027859130
-
Characterization of a new monoclonal antibody F4 detecting cell surface epitope and P-glycoprotein in drug-resistant human tumor cell lines
-
Chu, T.M., Kawinski, E., and Lin, T.H. 1993. Characterization of a new monoclonal antibody F4 detecting cell surface epitope and P-glycoprotein in drug-resistant human tumor cell lines. Hybridoma. 12:417-429.
-
(1993)
Hybridoma
, vol.12
, pp. 417-429
-
-
Chu, T.M.1
Kawinski, E.2
Lin, T.H.3
-
24
-
-
0014787893
-
The unlabeled antibody enzyme method of immunohistochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochaetes
-
Sternberger, L.A., Hardy, P.H., Cuculis J.J., and Meyer, H.G. 1970. The unlabeled antibody enzyme method of immunohistochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochaetes. J. Histochem. Cytochem. 18:315-334.
-
(1970)
J. Histochem. Cytochem.
, vol.18
, pp. 315-334
-
-
Sternberger, L.A.1
Hardy, P.H.2
Cuculis, J.J.3
Meyer, H.G.4
-
25
-
-
0027033641
-
Immunohistochemical quantification of steroid receptors and other prognosis factors in human breast cancer patients
-
Fritz, P., et al. 1992. Immunohistochemical quantification of steroid receptors and other prognosis factors in human breast cancer patients. J. Histochem. Cytochem. 26:146-158.
-
(1992)
J. Histochem. Cytochem.
, vol.26
, pp. 146-158
-
-
Fritz, P.1
-
26
-
-
0022186670
-
Measurment of protein using bichinonic acid
-
Smith, P.K., et al. 1985. Measurment of protein using bichinonic acid. Anal. Biochem. 150:76-85.
-
(1985)
Anal. Biochem.
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
-
27
-
-
0026464616
-
Identification of rifampicin-inducible P450IIIA4 (Cyp3A4) in human small bowel enterocytes
-
Kolars, J.C., Schmiedlin-Ren, P., Schuetz, J.D., Fang, C., and Watkins, P.B. 1992. Identification of rifampicin-inducible P450IIIA4 (Cyp3A4) in human small bowel enterocytes. J. Clin. Invest. 90:1871-1878.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1871-1878
-
-
Kolars, J.C.1
Schmiedlin-Ren, P.2
Schuetz, J.D.3
Fang, C.4
Watkins, P.B.5
-
28
-
-
12644278301
-
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
-
Sparreboom, A., et al. 1997. Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. Proc. Natl. Acad. Sci. USA. 94:2031-2035.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2031-2035
-
-
Sparreboom, A.1
-
29
-
-
12644272784
-
Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporin
-
Lown, K.S., et al. 1997. Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporin. Clin. Pharmacol. Ther. 62:248-260.
-
(1997)
Clin. Pharmacol. Ther.
, vol.62
, pp. 248-260
-
-
Lown, K.S.1
-
30
-
-
0026467167
-
Cyclosporine and quinidine inhibition of renal digoxin excretion: Evidence for luminal secretion of digoxin
-
de Lannoy, I.A.M., Koren, G., Klein, J., Charuk, J., and Silverman, M. 1992. Cyclosporine and quinidine inhibition of renal digoxin excretion: evidence for luminal secretion of digoxin. Am. J. Physiol 263:F613-F622.
-
(1992)
Am. J. Physiol
, vol.263
-
-
De Lannoy, I.A.M.1
Koren, G.2
Klein, J.3
Charuk, J.4
Silverman, M.5
-
31
-
-
0027856015
-
Digoxin-cyclosporin A interaction: Modulation of the multidrug transporter P-glycoprotein in the kidney
-
Okamura, N., et al. 1993. Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney. J. Pharmacol. Exp. Ther. 266:1614-1619.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.266
, pp. 1614-1619
-
-
Okamura, N.1
-
32
-
-
9044245300
-
Inhibition of the intestinal digoxin absorption and exsorption by quinidine
-
Su, S.F., and Huang, J.D. 1995. Inhibition of the intestinal digoxin absorption and exsorption by quinidine. Drug Metab. Dispos. 24:142-147.
-
(1995)
Drug Metab. Dispos.
, vol.24
, pp. 142-147
-
-
Su, S.F.1
Huang, J.D.2
-
33
-
-
0027818964
-
Role of P-glycoprotein in renal tubular secretion of digoxin in the isolated perfused rat kidney
-
Hori, R., Okamura, N., Aiba, T., and Tanigawara, Y. 1993. Role of P-glycoprotein in renal tubular secretion of digoxin in the isolated perfused rat kidney. J. Pharmacol. Exp. Ther. 266:1620-1625.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.266
, pp. 1620-1625
-
-
Hori, R.1
Okamura, N.2
Aiba, T.3
Tanigawara, Y.4
-
34
-
-
0027455141
-
The mechanism of the verapamil-digoxin interaction in renal tubular cells (LLC-PK1)
-
Ito, S., Woodland, C., Harper, P.A., and Koren, G. 1993. The mechanism of the verapamil-digoxin interaction in renal tubular cells (LLC-PK1). Life Sci. 53:PL399-PL403.
-
(1993)
Life Sci.
, vol.53
-
-
Ito, S.1
Woodland, C.2
Harper, P.A.3
Koren, G.4
-
35
-
-
0024496708
-
Interaction between digoxin and propafenone
-
Calvo, M.V., et al. 1989. Interaction between digoxin and propafenone. Ther. Drug Monit. 11:10-15.
-
(1989)
Ther. Drug Monit.
, vol.11
, pp. 10-15
-
-
Calvo, M.V.1
-
36
-
-
0031443240
-
Itraconazole decreases renal clearance of digoxin
-
Jalava, K.M., Partanen, J., and Neuvonen, P.J. 1997. Itraconazole decreases renal clearance of digoxin. Ther. Drug Monit. 19:609-613.
-
(1997)
Ther. Drug Monit.
, vol.19
, pp. 609-613
-
-
Jalava, K.M.1
Partanen, J.2
Neuvonen, P.J.3
-
37
-
-
0031914323
-
The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor
-
Calleja, C., Pascussi, J.M., Mani, J.C., Maurel, P., and Vilarem, M.J. 1998. The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor. Nat Med. 4:92-96.
-
(1998)
Nat Med.
, vol.4
, pp. 92-96
-
-
Calleja, C.1
Pascussi, J.M.2
Mani, J.C.3
Maurel, P.4
Vilarem, M.J.5
-
38
-
-
0030823456
-
Expression of P-glycoprotein 170 in nasal mucosa may be increased with topical steroids
-
Henriksson, G., Norlander, T., Zheng, X., Stierna, P., and Westrin, K.M. 1997. Expression of P-glycoprotein 170 in nasal mucosa may be increased with topical steroids. Am. J. Rhinol. 11:317-321.
-
(1997)
Am. J. Rhinol.
, vol.11
, pp. 317-321
-
-
Henriksson, G.1
Norlander, T.2
Zheng, X.3
Stierna, P.4
Westrin, K.M.5
-
39
-
-
0027169368
-
Modulation of multidrug resistance gene expression by dexamethasone in cultured hepatoma cells
-
Zhao, J.Y., Ikeguchi, M., Eckersberg, T., and Kuo, M.T. 1993. Modulation of multidrug resistance gene expression by dexamethasone in cultured hepatoma cells. Endocrinology. 133:521-528.
-
(1993)
Endocrinology
, vol.133
, pp. 521-528
-
-
Zhao, J.Y.1
Ikeguchi, M.2
Eckersberg, T.3
Kuo, M.T.4
|