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Volumn 24, Issue 2, 2019, Pages

Role of intestinal microbiota in the bioavailability and physiological functions of dietary polyphenols

Author keywords

Bioavailability; Intestinal microbiota; Microbial catabolite; Physiological function; Polyphenol; Prebiotics; Tannin

Indexed keywords

POLYPHENOL; PREBIOTIC AGENT;

EID: 85060390182     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules24020370     Document Type: Review
Times cited : (437)

References (168)
  • 1
    • 85045005772 scopus 로고    scopus 로고
    • Dietary flavonoids in the prevention of T2D: An overview
    • CrossRef PubMed
    • Alkhalidy, H.; Wang, Y.; Liu, D. Dietary flavonoids in the prevention of T2D: An overview. Nutrients 2018, 10, 438. [CrossRef] [PubMed]
    • (2018) Nutrients , vol.10 , pp. 438
    • Alkhalidy, H.1    Wang, Y.2    Liu, D.3
  • 2
    • 85030760798 scopus 로고    scopus 로고
    • Polyphenols: Dietary assessment and role in the prevention of cancers
    • Rothwell, J.A.; Knaze, V.; Zamora-Ros, R. Polyphenols: Dietary assessment and role in the prevention of cancers. Curr. Opin. Clin. Nutr. Metab. Care 2017, 20, 512–521. [CrossRef]
    • (2017) Curr. Opin. Clin. Nutr. Metab. Care , vol.20 , pp. 512-521
    • Rothwell, J.A.1    Knaze, V.2    Zamora-Ros, R.3
  • 3
    • 85041461589 scopus 로고    scopus 로고
    • Dietary polyphenols: Structures, bioavailability and protective effects against atherosclerosis
    • CrossRef PubMed
    • Santhakumar, A.B.; Battino, M.; Alvarez-Suarez, J.M. Dietary polyphenols: Structures, bioavailability and protective effects against atherosclerosis. Food Chem. Toxicol. 2018, 113, 49–65. [CrossRef] [PubMed]
    • (2018) Food Chem. Toxicol. , vol.113 , pp. 49-65
    • Santhakumar, A.B.1    Battino, M.2    Alvarez-Suarez, J.M.3
  • 4
    • 85043262358 scopus 로고    scopus 로고
    • Polyphenols and oxidative stress in atherosclerosis-related ischemic heart disease and stroke
    • CrossRef PubMed
    • Cheng, Y.C.; Sheen, J.M.; Hu, W.L.; Hung, Y.C. Polyphenols and Oxidative Stress in Atherosclerosis-Related Ischemic Heart Disease and Stroke. Oxid. Med. Cell. Longev. 2017, 2017, 8526438. [CrossRef] [PubMed]
    • (2017) Oxid. Med. Cell. Longev. , vol.2017 , pp. 8526438
    • Cheng, Y.C.1    Sheen, J.M.2    Hu, W.L.3    Hung, Y.C.4
  • 5
    • 85042554915 scopus 로고    scopus 로고
    • The potential and action mechanism of polyphenols in the treatment of liver diseases
    • Li, S.; Tan, H.Y.; Wang, N.; Cheung, F.; Hong, M.; Feng, Y. The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases. Oxid. Med. Cell. Longev. 2018, 2018, 8394818. [CrossRef]
    • (2018) Oxid. Med. Cell. Longev. , vol.2018 , pp. 8394818
    • Li, S.1    Tan, H.Y.2    Wang, N.3    Cheung, F.4    Hong, M.5    Feng, Y.6
  • 6
    • 84875953344 scopus 로고    scopus 로고
    • Dietary (Poly)phenolics in Human Health: Structures, bioavailability, and evidence of protective effects against chronic diseases
    • CrossRef PubMed
    • Del Rio, D.; Rodriguez-Mateos, A.; Spencer, J.P.E.; Tognolini, M.; Borges, G.; Crozier, A. Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases. Antioxid. Redox Signal. 2013, 18, 1818–1892. [CrossRef] [PubMed]
    • (2013) Antioxid. Redox Signal. , vol.18 , pp. 1818-1892
    • Del Rio, D.1    Rodriguez-Mateos, A.2    Spencer, J.P.E.3    Tognolini, M.4    Borges, G.5    Crozier, A.6
  • 8
    • 77549087040 scopus 로고    scopus 로고
    • Flavonoids: Metabolism bioavailability, and health impacts
    • Fraga, C.G., Ed.; John Wiley & Sons: Hoboken NJ, USA, CrossRef
    • Terao, J. Flavonoids: Metabolism bioavailability, and health impacts. In Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology; Fraga, C.G., Ed.; John Wiley & Sons: Hoboken NJ, USA, 2009; pp. 185–196. [CrossRef]
    • (2009) Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology , pp. 185-196
    • Terao, J.1
  • 12
    • 84866013013 scopus 로고    scopus 로고
    • Bioavailablity and bioefficacy of poly-phenols in humans, II: Review of 93 intervention studies
    • Williamson, G.; Manach, C. Bioavailablity and bioefficacy of poly-phenols in humans, II: Review of 93 intervention studies. Am.J.Clin.Nutr. 2005, 81, 2435–2555. [CrossRef]
    • (2005) Am.J.Clin.Nutr. , vol.81 , pp. 2435-2555
    • Williamson, G.1    Manach, C.2
  • 13
    • 67650267213 scopus 로고    scopus 로고
    • Dietary flavonoids as antioxidants
    • CrossRef PubMed
    • Terao, J. Dietary flavonoids as antioxidants. Forum Nutr. 2009, 61, 87–94. [CrossRef] [PubMed]
    • (2009) Forum Nutr , vol.61 , pp. 87-94
    • Terao, J.1
  • 14
    • 79955506452 scopus 로고    scopus 로고
    • The biological relevance of direct antioxidant effects of polyphenols for cardiovascular health in humans is not established
    • CrossRef PubMed
    • Hollman, P.C.H.; Cassidy, A.; Comte, B.; Heinonen, M.; Richelle, M.; Richling, E.; Serafini, M.; Scalbert, A.; Sies, H.; Vidry, S. The Biological Relevance of Direct Antioxidant Effects of Polyphenols for Cardiovascular Health in Humans Is Not Established. J. Nutr. 2011, 141, 989S–1009S. [CrossRef] [PubMed]
    • (2011) J. Nutr. , vol.141 , pp. 989S-1009S
    • Hollman, P.C.H.1    Cassidy, A.2    Comte, B.3    Heinonen, M.4    Richelle, M.5    Richling, E.6    Serafini, M.7    Scalbert, A.8    Sies, H.9    Vidry, S.10
  • 15
    • 84860520256 scopus 로고    scopus 로고
    • Target molecules of food phytochemicals: Food science bound for the next dimension
    • CrossRef PubMed
    • Murakami, A.; Ohnishi, K. Target molecules of food phytochemicals: Food science bound for the next dimension. Food Funct. 2012, 3, 462–476. [CrossRef] [PubMed]
    • (2012) Food Funct , vol.3 , pp. 462-476
    • Murakami, A.1    Ohnishi, K.2
  • 16
    • 84901741434 scopus 로고    scopus 로고
    • Hydrogen peroxide sensing, signaling and regulation of transcription factors
    • CrossRef PubMed
    • Marinho, H.S.; Real, C.; Cyrne, L.; Soares, H.; Antunes, F. Hydrogen peroxide sensing, signaling and regulation of transcription factors. Redox Biol. 2014, 2, 535–562. [CrossRef] [PubMed]
    • (2014) Redox Biol , vol.2 , pp. 535-562
    • Marinho, H.S.1    Real, C.2    Cyrne, L.3    Soares, H.4    Antunes, F.5
  • 17
    • 85017357323 scopus 로고    scopus 로고
    • Factors modulating bioavailability of quercetin-related flavonoids and the consequences of their vascular function
    • Terao, J. Factors modulating bioavailability of quercetin-related flavonoids and the consequences of their vascular function. Biochem. Pharmacol. 2017, 139, 15–23. [CrossRef]
    • (2017) Biochem. Pharmacol. , vol.139 , pp. 15-23
    • Terao, J.1
  • 18
    • 85018881939 scopus 로고    scopus 로고
    • Proanthocyanidins and hydrolysable tannins: Occurrence, dietary intake and pharmacological effects
    • Smeriglio, A.; Barreca, D.; Bellocco, E.; Trombetta, D. Proanthocyanidins and hydrolysable tannins: Occurrence, dietary intake and pharmacological effects. Br. J. Pharmacol. 2017, 174, 1244–1262. [CrossRef]
    • (2017) Br. J. Pharmacol. , vol.174 , pp. 1244-1262
    • Smeriglio, A.1    Barreca, D.2    Bellocco, E.3    Trombetta, D.4
  • 19
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh, P.J.; Ley, R.E.; Mahowald, M.A.; Magrini, V.; Mardis, E.R.; Gordon, J.I. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444, 1027–1031. [CrossRef]
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 20
    • 84964696945 scopus 로고    scopus 로고
    • Dietary polyphenols promote growth of the gut bacterium akkermansia muciniphila and attenuate high-fat diet-induced metabolic syndrome
    • CrossRef PubMed
    • Roopchand, D.E.; Carmody, R.N.; Kuhn, P.; Moskal, K.; Rojas-Silva, P.; Turnbaugh, P.J.; Raskin, I. Dietary polyphenols promote growth of the gut bacterium akkermansia muciniphila and attenuate high-fat diet-induced metabolic syndrome. Diabetes 2015, 64, 2847–2858. [CrossRef] [PubMed]
    • (2015) Diabetes , vol.64 , pp. 2847-2858
    • Roopchand, D.E.1    Carmody, R.N.2    Kuhn, P.3    Moskal, K.4    Rojas-Silva, P.5    Turnbaugh, P.J.6    Raskin, I.7
  • 21
    • 84982078839 scopus 로고    scopus 로고
    • Non-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changes
    • Masumoto, S.; Terao, A.; Yamamoto, Y.; Mukai, T.; Miura, T.; Shoji, T. Non-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changes. Sci. Rep. 2016, 6, 31208. [CrossRef]
    • (2016) Sci. Rep. , vol.6 , pp. 31208
    • Masumoto, S.1    Terao, A.2    Yamamoto, Y.3    Mukai, T.4    Miura, T.5    Shoji, T.6
  • 22
    • 84934451277 scopus 로고    scopus 로고
    • A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. Population in the gut microbiota of mice
    • Anhê, F.F.; Roy, D.; Pilon, G.; Dudonné, S.; Matamoros, S.; Varin, T.V.; Garofalo, C.; Moine, Q.; Desjardins, Y.; Levy, E.; et al. A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice. Gut 2015, 64, 872–883. [CrossRef]
    • (2015) Gut , vol.64 , pp. 872-883
    • Anhê, F.F.1    Roy, D.2    Pilon, G.3    Dudonné, S.4    Matamoros, S.5    Varin, T.V.6    Garofalo, C.7    Moine, Q.8    Desjardins, Y.9    Levy, E.10
  • 23
    • 84929461632 scopus 로고    scopus 로고
    • Quercetin and related polyphenols: New insights and implications for their bioactivity and bioavailability
    • CrossRef PubMed
    • Kawabata, K.; Mukai, R.; Ishisaka, A. Quercetin and related polyphenols: New insights and implications for their bioactivity and bioavailability. Food Funct. 2015, 6, 1399–1417. [CrossRef] [PubMed]
    • (2015) Food Funct , vol.6 , pp. 1399-1417
    • Kawabata, K.1    Mukai, R.2    Ishisaka, A.3
  • 24
    • 84909979667 scopus 로고    scopus 로고
    • Gut microbes and the brain: Paradigm shift in neuroscience
    • CrossRef PubMed
    • Mayer, E.A.; Knight, R.; Mazmanian, S.K.; Cryan, J.F.; Tillisch, K. Gut Microbes and the Brain: Paradigm Shift in Neuroscience. J. Neurosci. 2014, 34, 15490–15496. [CrossRef] [PubMed]
    • (2014) J. Neurosci. , vol.34 , pp. 15490-15496
    • Mayer, E.A.1    Knight, R.2    Mazmanian, S.K.3    Cryan, J.F.4    Tillisch, K.5
  • 25
    • 84866546211 scopus 로고    scopus 로고
    • Mind-altering microorganisms: The impact of the gut microbiota on brain and behaviour
    • CrossRef PubMed
    • Cryan, J.F.; Dinan, T.G. Mind-altering microorganisms: The impact of the gut microbiota on brain and behaviour. Nat. Rev. Neurosci. 2012, 13, 701–712. [CrossRef] [PubMed]
    • (2012) Nat. Rev. Neurosci. , vol.13 , pp. 701-712
    • Cryan, J.F.1    Dinan, T.G.2
  • 28
    • 85040169221 scopus 로고    scopus 로고
    • Metabolite of ellagitannins, urolithin A induces autophagy and inhibits metastasis in human sw620 colorectal cancer cells
    • CrossRef PubMed
    • Zhao, W.; Shi, F.; Guo, Z.; Zhao, J.; Song, X.; Yang, H. Metabolite of ellagitannins, urolithin A induces autophagy and inhibits metastasis in human sw620 colorectal cancer cells. Mol. Carcinog. 2018, 57, 193–200. [CrossRef] [PubMed]
    • (2018) Mol. Carcinog. , vol.57 , pp. 193-200
    • Zhao, W.1    Shi, F.2    Guo, Z.3    Zhao, J.4    Song, X.5    Yang, H.6
  • 29
    • 85043480025 scopus 로고    scopus 로고
    • Trimethylamine-N-oxide (TMAO)-induced impairment of cardiomyocyte function and the protective role of urolithin B-glucuronide
    • Savi, M.; Bocchi, L.; Bresciani, L.; Falco, A.; Quaini, F.; Mena, P.; Brighenti, F.; Crozier, A.; Stilli, D.; Del Rio, D. Trimethylamine-N-oxide (TMAO)-induced impairment of cardiomyocyte function and the protective role of urolithin B-glucuronide. Molecules 2018, 23, 549. [CrossRef]
    • (2018) Molecules , vol.23 , pp. 549
    • Savi, M.1    Bocchi, L.2    Bresciani, L.3    Falco, A.4    Quaini, F.5    Mena, P.6    Brighenti, F.7    Crozier, A.8    Stilli, D.9    Del Rio, D.10
  • 30
    • 70449124410 scopus 로고    scopus 로고
    • Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells
    • Kasimsetty, S.G.; Bialonska, D.; Reddy, M.K.; Thornton, C.; Willett, K.L.; Ferreira, D. Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells. J. Agric. Food Chem. 2009, 57, 10636–10644. [CrossRef]
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 10636-10644
    • Kasimsetty, S.G.1    Bialonska, D.2    Reddy, M.K.3    Thornton, C.4    Willett, K.L.5    Ferreira, D.6
  • 31
    • 79957628024 scopus 로고    scopus 로고
    • Impact of polyphenol metabolites produced by colonic microbiota on expression of COX-2 and GSTT2 in human colon cells (LT97)
    • Miene, C.; Weise, A.; Glei, M. Impact of polyphenol metabolites produced by colonic microbiota on expression of COX-2 and GSTT2 in human colon cells (LT97). Nutr. Cancer 2011, 63, 653–662. [CrossRef]
    • (2011) Nutr. Cancer , vol.63 , pp. 653-662
    • Miene, C.1    Weise, A.2    Glei, M.3
  • 32
    • 84925376931 scopus 로고    scopus 로고
    • Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH)
    • Surapaneni, K.M.; Priya, V.V.; Mallika, J. Pioglitazone, quercetin and hydroxy citric acid effect on cytochrome P450 2E1 (CYP2E1) enzyme levels in experimentally induced non alcoholic steatohepatitis (NASH). Eur. Rev. Med. Pharmacol. Sci. 2014, 18, 2736–2741. [CrossRef]
    • (2014) Eur. Rev. Med. Pharmacol. Sci. , vol.18 , pp. 2736-2741
    • Surapaneni, K.M.1    Priya, V.V.2    Mallika, J.3
  • 33
    • 84982676242 scopus 로고    scopus 로고
    • Bioactivity of polyphenols: Preventive and adjuvant strategies toward reducing inflammatory bowel diseases - Promises, perspectives, and pitfalls
    • CrossRef PubMed
    • Kaulmann, A.; Bohn, T. Bioactivity of Polyphenols: Preventive and Adjuvant Strategies toward Reducing Inflammatory Bowel Diseases - Promises, Perspectives, and Pitfalls. Oxid. Med. Cell. Longev. 2016, 9346470. [CrossRef] [PubMed]
    • (2016) Oxid. Med. Cell. Longev. , pp. 9346470
    • Kaulmann, A.1    Bohn, T.2
  • 34
    • 0043063961 scopus 로고    scopus 로고
    • Antioxidative flavonoid quercetin: Implication of its intestinal absorption and metabolism
    • Murota, K.; Terao, J. Antioxidative flavonoid quercetin: Implication of its intestinal absorption and metabolism. Arch. Biochem. Biophys. 2003, 417, 12–17. [CrossRef]
    • (2003) Arch. Biochem. Biophys. , vol.417 , pp. 12-17
    • Murota, K.1    Terao, J.2
  • 35
    • 85008440879 scopus 로고    scopus 로고
    • The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids
    • CrossRef PubMed
    • Cassidy, A.; Minihane, A.M. The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids. Am. J. Clin. Nutr. 2017, 105, 10–22. [CrossRef] [PubMed]
    • (2017) Am. J. Clin. Nutr. , vol.105 , pp. 10-22
    • Cassidy, A.1    Minihane, A.M.2
  • 36
    • 84888224134 scopus 로고    scopus 로고
    • Human studies on the absorption, distribution, metabolism, and excretion of tea polyphenols1-3
    • CrossRef PubMed
    • Clifford, M.N.; Van Der Hooft, J.J.J.; Crozier, A. Human studies on the absorption, distribution, metabolism, and excretion of tea polyphenols1-3. Am. J. Clin. Nutr. 2013, 98, 1619S–1630S. [CrossRef] [PubMed]
    • (2013) Am. J. Clin. Nutr. , vol.98 , pp. 1619S-1630S
    • Clifford, M.N.1    Van Der Hooft, J.J.J.2    Crozier, A.3
  • 37
    • 0043136588 scopus 로고    scopus 로고
    • Distribution pattern of a flavonoid extract in the gastrointestinal lumen and wall of rats
    • Pforte, H.; Hempel, J.; Jacobasch, G. Distribution pattern of a flavonoid extract in the gastrointestinal lumen and wall of rats. Nahrung 1999, 43, 205–208. [CrossRef]
    • (1999) Nahrung , vol.43 , pp. 205-208
    • Pforte, H.1    Hempel, J.2    Jacobasch, G.3
  • 39
    • 0036229187 scopus 로고    scopus 로고
    • Procyanidins are not bioavailable in rats fed a single meal containing a grapeseed extract or the procyanidin dimer B3
    • Donovan, J.L.; Lee, A.; Manach, C.; Rios, L.; Morand, C.; Scalbert, A.; Rémésy, C. Procyanidins are not bioavailable in rats fed a single meal containing a grapeseed extract or the procyanidin dimer B3. Br. J. Nutr. 2002, 87, 299–306. [CrossRef]
    • (2002) Br. J. Nutr. , vol.87 , pp. 299-306
    • Donovan, J.L.1    Lee, A.2    Manach, C.3    Rios, L.4    Morand, C.5    Scalbert, A.6    Rémésy, C.7
  • 45
    • 0037977138 scopus 로고    scopus 로고
    • Chlorogenic acid, quercetin-3-rutinoside and black tea phenols are extensively metabolized in humans
    • CrossRef PubMed
    • Olthof, M.R.; Hollman, P.C.H.; Buijsman, M.N.C.P.; van Amelsvoort, J.M.M.; Katan, M.B. Chlorogenic acid, quercetin-3-rutinoside and black tea phenols are extensively metabolized in humans. J. Nutr. 2003, 133, 1806–1814. [CrossRef] [PubMed]
    • (2003) J. Nutr. , vol.133 , pp. 1806-1814
    • Olthof, M.R.1    Hollman, P.C.H.2    Buijsman, M.N.C.P.3    Van Amelsvoort, J.M.M.4    Katan, M.B.5
  • 46
    • 33749249943 scopus 로고    scopus 로고
    • The relative contribution of the small and large intestine to the absorption and metabolism of rutin in man
    • CrossRef PubMed
    • Jaganath, I.B.; Mullen, W.; Edwards, C.A.; Crozier, A. The relative contribution of the small and large intestine to the absorption and metabolism of rutin in man. Free Radic. Res. 2006, 40, 1035–1046. [CrossRef] [PubMed]
    • (2006) Free Radic. Res. , vol.40 , pp. 1035-1046
    • Jaganath, I.B.1    Mullen, W.2    Edwards, C.A.3    Crozier, A.4
  • 47
    • 70249115522 scopus 로고    scopus 로고
    • In vitro catabolism of rutin by human fecal bacteria and the antioxidant capacity of its catabolites
    • CrossRef PubMed
    • Jaganath, I.B.; Mullen, W.; Lean, M.E.J.; Edwards, C.A.; Crozier, A. In vitro catabolism of rutin by human fecal bacteria and the antioxidant capacity of its catabolites. Free Radic. Biol. Med. 2009, 47, 1180–1189. [CrossRef] [PubMed]
    • (2009) Free Radic. Biol. Med. , vol.47 , pp. 1180-1189
    • Jaganath, I.B.1    Mullen, W.2    Lean, M.E.J.3    Edwards, C.A.4    Crozier, A.5
  • 48
    • 0037376885 scopus 로고    scopus 로고
    • Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: Differences between human and rat
    • Natsume, M.; Osakabe, N.; Oyama, M.; Sasaki, M.; Baba, S.; Nakamura, Y.; Osawa, T.; Terao, J. Structures of (-)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (-)-epicatechin: Differences between human and rat. Free Radic. Biol. Med. 2003, 34, 840–849. [CrossRef]
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 840-849
    • Natsume, M.1    Osakabe, N.2    Oyama, M.3    Sasaki, M.4    Baba, S.5    Nakamura, Y.6    Osawa, T.7    Terao, J.8
  • 49
    • 0034493222 scopus 로고    scopus 로고
    • Bioavailability of (-)-epicatechin upon intake of chocolate and cocoa in human volunteers
    • CrossRef PubMed
    • Baba, S.; Osakabe, N.; Yasuda, A.; Natsume, M.; Takizawa, T.; Nakamura, T.; Terao, J. Bioavailability of (-)-epicatechin upon intake of chocolate and cocoa in human volunteers. Free Radic. Res. 2000, 33, 635–641. [CrossRef] [PubMed]
    • (2000) Free Radic. Res. , vol.33 , pp. 635-641
    • Baba, S.1    Osakabe, N.2    Yasuda, A.3    Natsume, M.4    Takizawa, T.5    Nakamura, T.6    Terao, J.7
  • 51
    • 77649307443 scopus 로고    scopus 로고
    • Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy
    • Stalmach, A.; Mullen, W.; Steiling, H.; Williamson, G.; Lean, M.E.J.; Crozier, A. Absorption, metabolism, and excretion of green tea flavan-3-ols in humans with an ileostomy. Mol. Nutr. Food Res. 2010, 54, 323–334. [CrossRef]
    • (2010) Mol. Nutr. Food Res. , vol.54 , pp. 323-334
    • Stalmach, A.1    Mullen, W.2    Steiling, H.3    Williamson, G.4    Lean, M.E.J.5    Crozier, A.6
  • 52
    • 67649934106 scopus 로고    scopus 로고
    • Absorption, metabolism and excretion of Choladi green tea flavan-3-ols by humans
    • Stalmach, A.; Troufflard, S.; Serafini, M.; Crozier, A. Absorption, metabolism and excretion of Choladi green tea flavan-3-ols by humans. Mol. Nutr. Food Res. 2009, 53, 44–53. [CrossRef]
    • (2009) Mol. Nutr. Food Res. , vol.53 , pp. 44-53
    • Stalmach, A.1    Troufflard, S.2    Serafini, M.3    Crozier, A.4
  • 53
    • 84961755075 scopus 로고    scopus 로고
    • The absorption, distribution, metabolism and excretion of procyanidins
    • Zhang, L.; Wang, Y.; Li, D.; Ho, C.T.; Li, J.; Wan, X. The absorption, distribution, metabolism and excretion of procyanidins. Food Funct. 2016, 7, 1273–1281. [CrossRef]
    • (2016) Food Funct , vol.7 , pp. 1273-1281
    • Zhang, L.1    Wang, Y.2    Li, D.3    Ho, C.T.4    Li, J.5    Wan, X.6
  • 54
    • 84856911781 scopus 로고    scopus 로고
    • Transport of cranberry A-type procyanidin dimers, trimers, and tetramers across monolayers of human intestinal epithelial caco-2 cells
    • CrossRef PubMed
    • Ou, K.; Percival, S.S.; Zou, T.; Khoo, C.; Gu, L. Transport of cranberry A-type procyanidin dimers, trimers, and tetramers across monolayers of human intestinal epithelial caco-2 cells. J. Agric. Food Chem. 2012, 60, 1390–1396. [CrossRef] [PubMed]
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 1390-1396
    • Ou, K.1    Percival, S.S.2    Zou, T.3    Khoo, C.4    Gu, L.5
  • 55
    • 33244497325 scopus 로고    scopus 로고
    • Apple procyanidin oligomers absorption in rats after oral administration: Analysis of procyanidins in plasma using the porter method and high-performance liquid chromatography/tandem mass spectrometry
    • CrossRef PubMed
    • Shoji, T.; Masumoto, S.; Moriichi, N.; Akiyama, H.; Kanda, T.; Ohtake, Y.; Goda, Y. Apple procyanidin oligomers absorption in rats after oral administration: Analysis of procyanidins in plasma using the porter method and high-performance liquid chromatography/tandem mass spectrometry. J. Agric. Food Chem. 2006, 54, 884–892. [CrossRef] [PubMed]
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 884-892
    • Shoji, T.1    Masumoto, S.2    Moriichi, N.3    Akiyama, H.4    Kanda, T.5    Ohtake, Y.6    Goda, Y.7
  • 56
    • 77951209860 scopus 로고    scopus 로고
    • Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models
    • CrossRef PubMed
    • Serra, A.; Maci, A.; Romero, M.P.; Valls, J.; Bladé, C.; Arola, L.; Motilva, M.J. Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models. Br. J. Nutr. 2010, 103, 944–952. [CrossRef] [PubMed]
    • (2010) Br. J. Nutr. , vol.103 , pp. 944-952
    • Serra, A.1    Maci, A.2    Romero, M.P.3    Valls, J.4    Bladé, C.5    Arola, L.6    Motilva, M.J.7
  • 58
    • 0036628736 scopus 로고    scopus 로고
    • Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats
    • Baba, S.; Osakabe, N.; Natsume, M.; Terao, J. Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats. Free Radic. Biol. Med. 2002, 33, 142–148. [CrossRef]
    • (2002) Free Radic. Biol. Med. , vol.33 , pp. 142-148
    • Baba, S.1    Osakabe, N.2    Natsume, M.3    Terao, J.4
  • 59
    • 67749147086 scopus 로고    scopus 로고
    • Procyanidin dimers A1, A2, and B2 are absorbed without conjugation or methylation from the small intestine of rats
    • Appeldoorn, M.M.; Vincken, J.-P.; Gruppen, H.; Hollman, P.C.H. Procyanidin Dimers A1, A2, and B2 Are Absorbed without Conjugation or Methylation from the Small Intestine of Rats. J. Nutr. 2009, 139, 1469–1473. [CrossRef]
    • (2009) J. Nutr. , vol.139 , pp. 1469-1473
    • Appeldoorn, M.M.1    Vincken, J.-P.2    Gruppen, H.3    Hollman, P.C.H.4
  • 60
    • 84959284188 scopus 로고    scopus 로고
    • Urinary metabolites from mango (Mangifera indica L. Cv. Keitt) galloyl derivatives and in vitro hydrolysis of gallotannins in physiological conditions
    • CrossRef PubMed
    • Barnes, R.C.; Krenek, K.A.; Meibohm, B.; Mertens-Talcott, S.U.; Talcott, S.T. Urinary metabolites from mango (Mangifera indica L. cv. Keitt) galloyl derivatives and in vitro hydrolysis of gallotannins in physiological conditions. Mol. Nutr. Food Res. 2016, 60, 542–550. [CrossRef] [PubMed]
    • (2016) Mol. Nutr. Food Res. , vol.60 , pp. 542-550
    • Barnes, R.C.1    Krenek, K.A.2    Meibohm, B.3    Mertens-Talcott, S.U.4    Talcott, S.T.5
  • 61
    • 4444365417 scopus 로고    scopus 로고
    • Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice
    • Seeram, N.P.; Lee, R.; Heber, D. Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice. Clin. Chim. Acta 2004, 348, 63–68. [CrossRef]
    • (2004) Clin. Chim. Acta , vol.348 , pp. 63-68
    • Seeram, N.P.1    Lee, R.2    Heber, D.3
  • 62
    • 77950640680 scopus 로고    scopus 로고
    • Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy
    • CrossRef PubMed
    • González-Barrio, R.; Borges, G.; Mullen, W.; Crozier, A. Bioavailability of anthocyanins and ellagitannins following consumption of raspberries by healthy humans and subjects with an ileostomy. J. Agric. Food Chem. 2010, 58, 3933–3939. [CrossRef] [PubMed]
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 3933-3939
    • González-Barrio, R.1    Borges, G.2    Mullen, W.3    Crozier, A.4
  • 64
    • 80052261264 scopus 로고    scopus 로고
    • Metabolic pathways of the colonic metabolism of flavonoids (flavonols, flavones and flavanones) and phenolic acids
    • Serra, A.; MacIà, A.; Romero, M.P.; Reguant, J.; Ortega, N.; Motilva, M.J. Metabolic pathways of the colonic metabolism of flavonoids (flavonols, flavones and flavanones) and phenolic acids. Food Chem. 2012, 130, 383–393. [CrossRef]
    • (2012) Food Chem , vol.130 , pp. 383-393
    • Serra, A.1    MacIà, A.2    Romero, M.P.3    Reguant, J.4    Ortega, N.5    Motilva, M.J.6
  • 65
    • 41849099278 scopus 로고    scopus 로고
    • Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by fluorescence in situ hybridization (FISH)
    • CrossRef PubMed
    • Hein, E.M.; Rose, K.; Van’t Slot, G.; Friedrich, A.W.; Humpf, H.U. Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by fluorescence in situ hybridization (FISH). J. Agric. Food Chem. 2008, 56, 2281–2290. [CrossRef] [PubMed]
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 2281-2290
    • Hein, E.M.1    Rose, K.2    Van’t Slot, G.3    Friedrich, A.W.4    Humpf, H.U.5
  • 66
    • 84899048608 scopus 로고    scopus 로고
    • In vitro catabolism of quercetin by human fecal bacteria and the antioxidant capacity of its catabolites
    • Peng, X.; Zhang, Z.; Zhang, N.; Liu, L.; Li, S.; Wei, H. In vitro catabolism of quercetin by human fecal bacteria and the antioxidant capacity of its catabolites. Food Nutr. Res. 2014, 58, 23406. [CrossRef]
    • (2014) Food Nutr. Res. , vol.58 , pp. 23406
    • Peng, X.1    Zhang, Z.2    Zhang, N.3    Liu, L.4    Li, S.5    Wei, H.6
  • 67
    • 0034528031 scopus 로고    scopus 로고
    • Degradation of quercetin-3-glucoside in gnotobiotic rats associated with human intestinal bacteria
    • CrossRef PubMed
    • Schneider, H.; Simmering, R.; Hartmann, L.; Pforte, H.; Blaut, M. Degradation of quercetin-3-glucoside in gnotobiotic rats associated with human intestinal bacteria. J. Appl. Microbiol. 2000, 89, 1027–1037. [CrossRef] [PubMed]
    • (2000) J. Appl. Microbiol. , vol.89 , pp. 1027-1037
    • Schneider, H.1    Simmering, R.2    Hartmann, L.3    Pforte, H.4    Blaut, M.5
  • 68
    • 0026463538 scopus 로고
    • Role of the gastrointestinal mucosa and microflora in the bioactivation of dietary and environmental mutagens or carcinogens
    • CrossRef PubMed
    • Chadwick, R.W.; George, S.E.; Claxton, L.D. Role of the gastrointestinal mucosa and microflora in the bioactivation of dietary and environmental mutagens or carcinogens. Drug Metab. Rev. 1992, 24, 425–492. [CrossRef] [PubMed]
    • (1992) Drug Metab. Rev. , vol.24 , pp. 425-492
    • Chadwick, R.W.1    George, S.E.2    Claxton, L.D.3
  • 69
    • 77955376981 scopus 로고    scopus 로고
    • Excess production of Bacillus subtilis quercetin 2,3-dioxygenase affects cell viability in the presence of quercetin
    • CrossRef PubMed
    • Hirooka, K.; Fujita, Y. Excess production of Bacillus subtilis quercetin 2,3-dioxygenase affects cell viability in the presence of quercetin. Biosci. Biotechnol. Biochem. 2010, 74, 1030–1038. [CrossRef] [PubMed]
    • (2010) Biosci. Biotechnol. Biochem. , vol.74 , pp. 1030-1038
    • Hirooka, K.1    Fujita, Y.2
  • 70
    • 31044441352 scopus 로고    scopus 로고
    • Kinetic and spectroscopic studies on the quercetin 2,3-dioxygenase from Bacillus subtilis
    • CrossRef PubMed
    • Schaab, M.R.; Barney, B.M.; Francisco, W.A. Kinetic and spectroscopic studies on the quercetin 2,3-dioxygenase from Bacillus subtilis. Biochemistry 2006, 45, 1009–1016. [CrossRef] [PubMed]
    • (2006) Biochemistry , vol.45 , pp. 1009-1016
    • Schaab, M.R.1    Barney, B.M.2    Francisco, W.A.3
  • 71
    • 84938773548 scopus 로고    scopus 로고
    • Catalytic dioxygenation of flavonol by MII-complexes (M = Mn, Fe, Co, Ni, Cu and Zn)-mimicking the MII-substituted quercetin 2,3-dioxygenase
    • CrossRef PubMed
    • Sun, Y.J.; Huang, Q.Q.; Li, P.; Zhang, J.J. Catalytic dioxygenation of flavonol by MII-complexes (M = Mn, Fe, Co, Ni, Cu and Zn)-mimicking the MII-substituted quercetin 2,3-dioxygenase. Dalt. Trans. 2015, 44, 13926–13938. [CrossRef] [PubMed]
    • (2015) Dalt. Trans. , vol.44 , pp. 13926-13938
    • Sun, Y.J.1    Huang, Q.Q.2    Li, P.3    Zhang, J.J.4
  • 72
    • 84861180869 scopus 로고    scopus 로고
    • Ring-cleaving dioxygenases with a cupin fold
    • Fetzner, S. Ring-Cleaving Dioxygenases with a Cupin Fold. Appl. Environ. Microbiol. 2012, 78, 2505–2514. [CrossRef]
    • (2012) Appl. Environ. Microbiol. , vol.78 , pp. 2505-2514
    • Fetzner, S.1
  • 73
    • 84949115106 scopus 로고    scopus 로고
    • The microbial degradation of onion flavonol glucosides and their roasting products by the human gut bacteria Eubacterium ramulus and Flavonifractor plautii
    • Ulbrich, K.; Reichardt, N.; Braune, A.; Krohd, L.W.; Blaut, M.; Rohn, S. The microbial degradation of onion flavonol glucosides and their roasting products by the human gut bacteria Eubacterium ramulus and Flavonifractor plautii. Food Res. Int. 2015, 67, 349–355. [CrossRef]
    • (2015) Food Res. Int. , vol.67 , pp. 349-355
    • Ulbrich, K.1    Reichardt, N.2    Braune, A.3    Krohd, L.W.4    Blaut, M.5    Rohn, S.6
  • 74
    • 84929888251 scopus 로고    scopus 로고
    • Anoxic conditions promote species-specific mutualism between gut microbes in silico
    • CrossRef PubMed
    • Heinken, A.; Thiele, I. Anoxic Conditions Promote Species-Specific Mutualism between Gut Microbes In Silico. Appl Env. Microbiol 2015, 81, 4049–4061. [CrossRef] [PubMed]
    • (2015) Appl Env. Microbiol , vol.81 , pp. 4049-4061
    • Heinken, A.1    Thiele, I.2
  • 75
    • 36849055112 scopus 로고    scopus 로고
    • Hypoxia and gastrointestinal disease
    • CrossRef PubMed
    • Taylor, C.T.; Colgan, S.P. Hypoxia and gastrointestinal disease. J. Mol. Med. 2007, 85, 1295–1300. [CrossRef] [PubMed]
    • (2007) J. Mol. Med. , vol.85 , pp. 1295-1300
    • Taylor, C.T.1    Colgan, S.P.2
  • 76
    • 0029153686 scopus 로고
    • The anaerobic life of Bacillus subtilis: Cloning of the genes encoding the respiratory nitrate reductase system
    • CrossRef PubMed
    • Hoffmann, T.; Troup, B.; Szabo, A.; Hungerer, C.; Jahn, D. The anaerobic life of Bacillus subtilis: Cloning of the genes encoding the respiratory nitrate reductase system. FEMS Microbiol. Lett. 1995, 131, 219–225. [CrossRef] [PubMed]
    • (1995) FEMS Microbiol. Lett. , vol.131 , pp. 219-225
    • Hoffmann, T.1    Troup, B.2    Szabo, A.3    Hungerer, C.4    Jahn, D.5
  • 78
    • 1642573174 scopus 로고    scopus 로고
    • Bacillus subtilis YxaG is a novel Fe-containing quercetin 2,3-dioxygenase
    • Bowater, L.; Fairhurst, S.A.; Just, V.J.; Bornemann, S. Bacillus subtilis YxaG is a novel Fe-containing quercetin 2,3-dioxygenase. FEBS Lett. 2004, 557, 45–48. [CrossRef]
    • (2004) FEBS Lett , vol.557 , pp. 45-48
    • Bowater, L.1    Fairhurst, S.A.2    Just, V.J.3    Bornemann, S.4
  • 79
    • 1542286856 scopus 로고    scopus 로고
    • Concentrations of proanthocyanidins in common foods and estimations of normal consumption
    • CrossRef PubMed
    • Gu, L.; Kelm, M.A.; Hammerstone, J.F.; Beecher, G.; Holden, J.; Haytowitz, D.; Gebhardt, S.; Prior, R.L. Concentrations of Proanthocyanidins in Common Foods and Estimations of Normal Consumption. J. Nutr. 2004, 134, 613–617. [CrossRef] [PubMed]
    • (2004) J. Nutr. , vol.134 , pp. 613-617
    • Gu, L.1    Kelm, M.A.2    Hammerstone, J.F.3    Beecher, G.4    Holden, J.5    Haytowitz, D.6    Gebhardt, S.7    Prior, R.L.8
  • 80
    • 15044340025 scopus 로고    scopus 로고
    • Dietary proanthocyanidins: Occurrence, dietary intake, bioavailability, and protection against cardiovascular disease
    • Rasmussen, S.E.; Frederiksen, H.; Krogholm, K.S.; Poulsen, L. Dietary proanthocyanidins: Occurrence, dietary intake, bioavailability, and protection against cardiovascular disease. Mol. Nutr. Food Res. 2005, 49, 159–174. [CrossRef]
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 159-174
    • Rasmussen, S.E.1    Frederiksen, H.2    Krogholm, K.S.3    Poulsen, L.4
  • 81
    • 61449211248 scopus 로고    scopus 로고
    • Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-dihydroxyphenyl)-γ-valerolactone as the major metabolites
    • Appeldoorn, M.M.; Vincken, J.P.; Aura, A.M.; Hollman, P.C.H.; Gruppen, H. Procyanidin dimers are metabolized by human microbiota with 2-(3,4-dihydroxyphenyl)acetic acid and 5-(3,4-dihydroxyphenyl)-γ-valerolactone as the major metabolites. J. Agric. Food Chem. 2009, 57, 1084–1092. [CrossRef]
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 1084-1092
    • Appeldoorn, M.M.1    Vincken, J.P.2    Aura, A.M.3    Hollman, P.C.H.4    Gruppen, H.5
  • 83
    • 84897430278 scopus 로고    scopus 로고
    • Simultaneous UPLC-MS/MS analysis of native catechins and procyanidins and their microbial metabolites in intestinal contents and tissues of Male Wistar Furth inbred rats
    • Goodrich, K.M.; Neilson, A.P. Simultaneous UPLC-MS/MS analysis of native catechins and procyanidins and their microbial metabolites in intestinal contents and tissues of male Wistar Furth inbred rats. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2014, 958, 63–74. [CrossRef]
    • (2014) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.958 , pp. 63-74
    • Goodrich, K.M.1    Neilson, A.P.2
  • 85
    • 84905753789 scopus 로고    scopus 로고
    • A rapid method to determine colonic microbial metabolites derived from grape flavanols in rat plasma by liquid chromatography-tandem mass spectrometry
    • CrossRef PubMed
    • Margalef, M.; Pons, Z.; Muguerza, B.; Arola-Arnal, A. A rapid method to determine colonic microbial metabolites derived from grape flavanols in rat plasma by liquid chromatography-tandem mass spectrometry. J. Agric. Food Chem. 2014, 62, 7698–7706. [CrossRef] [PubMed]
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 7698-7706
    • Margalef, M.1    Pons, Z.2    Muguerza, B.3    Arola-Arnal, A.4
  • 86
    • 84928647961 scopus 로고    scopus 로고
    • Highly sensitive analysis of polyphenols and their metabolites in human blood cells using dispersive SPE extraction and LC-MS/MS
    • Mülek, M.; Högger, P. Highly sensitive analysis of polyphenols and their metabolites in human blood cells using dispersive SPE extraction and LC-MS/MS. Anal. Bioanal. Chem. 2015, 407, 1885–1899. [CrossRef]
    • (2015) Anal. Bioanal. Chem. , vol.407 , pp. 1885-1899
    • Mülek, M.1    Högger, P.2
  • 87
    • 84878218577 scopus 로고    scopus 로고
    • Catabolism of (+)-catechin and (-)-epicatechin by rat intestinal microbiota
    • CrossRef PubMed
    • Takagaki, A.; Nanjo, F. Catabolism of (+)-catechin and (-)-epicatechin by rat intestinal microbiota. J. Agric. Food Chem. 2013, 61, 4927–4935. [CrossRef] [PubMed]
    • (2013) J. Agric. Food Chem. , vol.61 , pp. 4927-4935
    • Takagaki, A.1    Nanjo, F.2
  • 88
    • 2542494981 scopus 로고    scopus 로고
    • Bioavailability of anthocyanidin-3-glycosides following consumption of elderberry extract and blackcurrant juice
    • CrossRef PubMed
    • Bitsch, I.; Janssen, M.; Netzel, M.; Strass, G.; Frank, T. Bioavailability of anthocyanidin-3-glycosides following consumption of elderberry extract and blackcurrant juice. Int. J. Clin. Pharmacol. Ther. 2004, 42, 293–300. [CrossRef] [PubMed]
    • (2004) Int. J. Clin. Pharmacol. Ther. , vol.42 , pp. 293-300
    • Bitsch, I.1    Janssen, M.2    Netzel, M.3    Strass, G.4    Frank, T.5
  • 89
    • 0034788719 scopus 로고    scopus 로고
    • Malvidin-3-glucoside bioavailability in humans after ingestion of red wine, dealcoholized red wine and red grape juice
    • CrossRef PubMed
    • Bub, A.; Watzl, B.; Heeb, D.; Rechkemmer, G.; Briviba, K. Malvidin-3-glucoside bioavailability in humans after ingestion of red wine, dealcoholized red wine and red grape juice. Eur. J. Nutr. 2001, 40, 113–120. [CrossRef] [PubMed]
    • (2001) Eur. J. Nutr. , vol.40 , pp. 113-120
    • Bub, A.1    Watzl, B.2    Heeb, D.3    Rechkemmer, G.4    Briviba, K.5
  • 90
  • 92
    • 52649120818 scopus 로고    scopus 로고
    • Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich açai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers
    • CrossRef PubMed
    • Mertens-Talcott, S.U.; Rios, J.; Jilma-Stohlawetz, P.; Pacheco-Palencia, L.A.; Meibohm, B.; Talcott, S.T.; Derendorf, H. Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich açai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. J. Agric. Food Chem. 2008, 56, 7796–7802. [CrossRef] [PubMed]
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 7796-7802
    • Mertens-Talcott, S.U.1    Rios, J.2    Jilma-Stohlawetz, P.3    Pacheco-Palencia, L.A.4    Meibohm, B.5    Talcott, S.T.6    Derendorf, H.7
  • 94
    • 3142516348 scopus 로고    scopus 로고
    • Anthocyanin metabolites in human urine and serum
    • CrossRef PubMed
    • Kay, C.D.; Mazza, G.; Holub, B.J.; Wang, J. Anthocyanin metabolites in human urine and serum. Br. J. Nutr. 2004, 91, 933–942. [CrossRef] [PubMed]
    • (2004) Br. J. Nutr. , vol.91 , pp. 933-942
    • Kay, C.D.1    Mazza, G.2    Holub, B.J.3    Wang, J.4
  • 97
    • 78650523303 scopus 로고    scopus 로고
    • Oxidation of benzoins to benzoic acids using sodium hydride under oxygen atmosphere
    • Kang, S.; Joo, C.; Kim, S.M.; Han, H.; Yang, J.W. Oxidation of benzoins to benzoic acids using sodium hydride under oxygen atmosphere. Tetrahedron Lett. 2011, 52, 502–504. [CrossRef]
    • (2011) Tetrahedron Lett , vol.52 , pp. 502-504
    • Kang, S.1    Joo, C.2    Kim, S.M.3    Han, H.4    Yang, J.W.5
  • 98
    • 84930178829 scopus 로고    scopus 로고
    • Anthocyanins and their physiologically relevant metabolites alter the expression of IL-6 and VCAM-1 in CD40L and oxidized LDL challenged vascular endothelial cells
    • CrossRef PubMed
    • Amin, H.P.; Czank, C.; Raheem, S.; Zhang, Q.; Botting, N.P.; Cassidy, A.; Kay, C.D. Anthocyanins and their physiologically relevant metabolites alter the expression of IL-6 and VCAM-1 in CD40L and oxidized LDL challenged vascular endothelial cells. Mol. Nutr. Food Res. 2015, 59, 1095–1106. [CrossRef] [PubMed]
    • (2015) Mol. Nutr. Food Res. , vol.59 , pp. 1095-1106
    • Amin, H.P.1    Czank, C.2    Raheem, S.3    Zhang, Q.4    Botting, N.P.5    Cassidy, A.6    Kay, C.D.7
  • 99
    • 84866973849 scopus 로고    scopus 로고
    • Gut microbiota metabolism of anthocyanin promotes reverse cholesterol transport in mice via repressing miRNA-10b
    • CrossRef PubMed
    • Wang, D.; Xia, M.; Yan, X.; Li, D.; Wang, L.; Xu, Y.; Jin, T.; Ling, W. Gut microbiota metabolism of anthocyanin promotes reverse cholesterol transport in mice via repressing miRNA-10b. Circ. Res. 2012, 111, 967–981. [CrossRef] [PubMed]
    • (2012) Circ. Res. , vol.111 , pp. 967-981
    • Wang, D.1    Xia, M.2    Yan, X.3    Li, D.4    Wang, L.5    Xu, Y.6    Jin, T.7    Ling, W.8
  • 100
    • 79952174576 scopus 로고    scopus 로고
    • Anthocyanin-derived phenolic acids form glucuronides following simulated gastrointestinal digestion and microsomal glucuronidation
    • CrossRef PubMed
    • Woodward, G.M.; Needs, P.W.; Kay, C.D. Anthocyanin-derived phenolic acids form glucuronides following simulated gastrointestinal digestion and microsomal glucuronidation. Mol. Nutr. Food Res. 2011, 55, 378–386. [CrossRef] [PubMed]
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 378-386
    • Woodward, G.M.1    Needs, P.W.2    Kay, C.D.3
  • 101
    • 0018222291 scopus 로고
    • The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat
    • Holder, G.M.; Plummer, J.L.; Ryan, A.J. The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat. Xenobiotica 1978, 8, 761–768. [CrossRef]
    • (1978) Xenobiotica , vol.8 , pp. 761-768
    • Holder, G.M.1    Plummer, J.L.2    Ryan, A.J.3
  • 103
    • 79955598016 scopus 로고    scopus 로고
    • Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism
    • Hassaninasab, A.; Hashimoto, Y.; Tomita-Yokotani, K.; Kobayashi, M. Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism. Proc. Natl. Acad. Sci. USA 2011, 108, 6615–6620. [CrossRef]
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 6615-6620
    • Hassaninasab, A.1    Hashimoto, Y.2    Tomita-Yokotani, K.3    Kobayashi, M.4
  • 105
    • 12344282206 scopus 로고    scopus 로고
    • Metabolism of antioxidant and chemopreventive ellagitannins from strawberries, raspberries, walnuts, and oak-aged wine in humans: Identification of biomarkers and individual variability
    • Cerdá, B.; Tomás-Barberán, F.A.; Espín, J.C. Metabolism of antioxidant and chemopreventive ellagitannins from strawberries, raspberries, walnuts, and oak-aged wine in humans: Identification of biomarkers and individual variability. J. Agric. Food Chem. 2005, 53, 227–235. [CrossRef]
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 227-235
    • Cerdá, B.1    Tomás-Barberán, F.A.2    Espín, J.C.3
  • 106
    • 33646405748 scopus 로고    scopus 로고
    • Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
    • CrossRef PubMed
    • González, C.A.; Pera, G.; Agudo, A.; Bueno-De-Mesquita, H.B.; Ceroti, M.; Boeing, H.; Schulz, M.; Del Giudice, G.; Plebani, M.; Carneiro, F.; et al. Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Int. J. Cancer 2006, 118, 2559–2566. [CrossRef] [PubMed]
    • (2006) Int. J. Cancer , vol.118 , pp. 2559-2566
    • González, C.A.1    Pera, G.2    Agudo, A.3    Bueno-De-Mesquita, H.B.4    Ceroti, M.5    Boeing, H.6    Schulz, M.7    Del Giudice, G.8    Plebani, M.9    Carneiro, F.10
  • 107
    • 33749494522 scopus 로고    scopus 로고
    • Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours
    • CrossRef PubMed
    • Seeram, N.P.; Henning, S.M.; Zhang, Y.; Suchard, M.; Li, Z.; Heber, D. Pomegranate Juice Ellagitannin Metabolites Are Present in Human Plasma and Some Persist in Urine for Up to 48 Hours. J. Nutr. 2006, 136, 2481–2485. [CrossRef] [PubMed]
    • (2006) J. Nutr. , vol.136 , pp. 2481-2485
    • Seeram, N.P.1    Henning, S.M.2    Zhang, Y.3    Suchard, M.4    Li, Z.5    Heber, D.6
  • 110
    • 84904437984 scopus 로고    scopus 로고
    • Ellagic acid metabolism by human gut microbiota: Consistent observation of three urolithin phenotypes in intervention trials, independent of food source, age, and health status
    • CrossRef PubMed
    • Tomás-Barberán, F.A.; García-Villalba, R.; González-Sarrías, A.; Selma, M.V.; Espín, J.C. Ellagic acid metabolism by human gut microbiota: Consistent observation of three urolithin phenotypes in intervention trials, independent of food source, age, and health status. J. Agric. Food Chem. 2014, 62, 6535–6538. [CrossRef] [PubMed]
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 6535-6538
    • Tomás-Barberán, F.A.1    García-Villalba, R.2    González-Sarrías, A.3    Selma, M.V.4    Espín, J.C.5
  • 111
  • 113
    • 11844285673 scopus 로고    scopus 로고
    • Absorption, bioavailability, and metabolism of flavonoids
    • Hollman, P.C.H. Absorption, Bioavailability, and Metabolism of Flavonoids. Pharm. Biol. 2009, 42, 74–83. [CrossRef]
    • (2009) Pharm. Biol. , vol.42 , pp. 74-83
    • Hollman, P.C.H.1
  • 114
    • 0033863355 scopus 로고    scopus 로고
    • Dietary intake and bioavailability of polyphenols
    • Scalbert, A.; Williamson, G. Dietary Intake and Bioavailability of Polyphenols. J. Nutr. 2000, 130, 2073S–2085S. [CrossRef]
    • (2000) J. Nutr. , vol.130 , pp. 2073S-2085S
    • Scalbert, A.1    Williamson, G.2
  • 115
    • 12144262315 scopus 로고    scopus 로고
    • Diet-derived phenols in plasma and tissues and their implications for health
    • CrossRef PubMed
    • Clifford, M.N. Diet-derived phenols in plasma and tissues and their implications for health. Planta Med. 2004, 70, 1103–1114. [CrossRef] [PubMed]
    • (2004) Planta Med , vol.70 , pp. 1103-1114
    • Clifford, M.N.1
  • 116
  • 117
    • 84904968388 scopus 로고    scopus 로고
    • Flavonoids and phenolic acids from cranberry juice are bioavailable and bioactive in healthy older adults
    • CrossRef PubMed
    • McKay, D.L.; Chen, C.Y.O.; Zampariello, C.A.; Blumberg, J.B. Flavonoids and phenolic acids from cranberry juice are bioavailable and bioactive in healthy older adults. Food Chem. 2015, 168, 233–240. [CrossRef] [PubMed]
    • (2015) Food Chem , vol.168 , pp. 233-240
    • McKay, D.L.1    Chen, C.Y.O.2    Zampariello, C.A.3    Blumberg, J.B.4
  • 118
    • 84865762064 scopus 로고    scopus 로고
    • Prebiotic effects of yacon (Smallanthus sonchifolius Poepp. & Endl), a source of fructooligosaccharides and phenolic compounds with antioxidant activity
    • CrossRef PubMed
    • Campos, D.; Betalleluz-Pallardel, I.; Chirinos, R.; Aguilar-Galvez, A.; Noratto, G.; Pedreschi, R. Prebiotic effects of yacon (Smallanthus sonchifolius Poepp. & Endl), a source of fructooligosaccharides and phenolic compounds with antioxidant activity. Food Chem. 2012, 135, 1592–1599. [CrossRef] [PubMed]
    • (2012) Food Chem , vol.135 , pp. 1592-1599
    • Campos, D.1    Betalleluz-Pallardel, I.2    Chirinos, R.3    Aguilar-Galvez, A.4    Noratto, G.5    Pedreschi, R.6
  • 119
    • 64549135899 scopus 로고    scopus 로고
    • Oligosaccharide promotes bioavailability of a water-soluble flavonoid glycoside, αG-rutin, in rats
    • CrossRef PubMed
    • Matsukawa, N.; Matsumoto, M.; Chiji, H.; Hara, H. Oligosaccharide promotes bioavailability of a water-soluble flavonoid glycoside, αG-rutin, in rats. J. Agric. Food Chem. 2009, 57, 1498–1505. [CrossRef] [PubMed]
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 1498-1505
    • Matsukawa, N.1    Matsumoto, M.2    Chiji, H.3    Hara, H.4
  • 120
    • 46749097580 scopus 로고    scopus 로고
    • Pomegranate juice and extracts provide similar levels of plasma and urinary ellagitannin metabolites in human subjects
    • Seeram, N.P.; Zhang, Y.; McKeever, R.; Henning, S.M.; Lee, R.; Suchard, M.A.; Li, Z.; Chen, S.; Thames, G.; Zerlin, A.; et al. Pomegranate Juice and Extracts Provide Similar Levels of Plasma and Urinary Ellagitannin Metabolites in Human Subjects. J. Med. Food 2008, 11, 390–394. [CrossRef]
    • (2008) J. Med. Food , vol.11 , pp. 390-394
    • Seeram, N.P.1    Zhang, Y.2    McKeever, R.3    Henning, S.M.4    Lee, R.5    Suchard, M.A.6    Li, Z.7    Chen, S.8    Thames, G.9    Zerlin, A.10
  • 121
    • 0025895019 scopus 로고
    • The effects of pH and rat intestinal contents on the liberation of ellagic acid from purified and crude ellagitannins
    • Daniel, E.M.; Ratnayake, S.; Kinstle, T.; Stoner, G.D. The effects of pH and rat intestinal contents on the liberation of ellagic acid from purified and crude ellagitannins. J. Nat. Prod. 1991, 54, 946–952. [CrossRef]
    • (1991) J. Nat. Prod. , vol.54 , pp. 946-952
    • Daniel, E.M.1    Ratnayake, S.2    Kinstle, T.3    Stoner, G.D.4
  • 123
    • 85060654593 scopus 로고    scopus 로고
    • Of the major phenolic acids formed during human microbial fermentation of tea, citrus, and soy flavonoid supplements, only
    • Has, A.; Activity, A.; Gao, K.; Xu, A.; Krul, C.; Venema, K.; Liu, Y.; Niu, Y.; Lu, J.; Bensoussan, L.; et al. Of the Major Phenolic Acids Formed during Human Microbial Fermentation of Tea, Citrus, and Soy Flavonoid Supplements, Only. Joournal Nutr. 2006, 136, 52–57. [CrossRef]
    • (2006) Joournal Nutr , vol.136 , pp. 52-57
    • Has, A.1    Activity, A.2    Gao, K.3    Xu, A.4    Krul, C.5    Venema, K.6    Liu, Y.7    Niu, Y.8    Lu, J.9    Bensoussan, L.10
  • 124
    • 85041611921 scopus 로고    scopus 로고
    • Bioavailable blueberry-derived phenolic acids at physiological concentrations enhance Nrf2-regulated antioxidant responses in human vascular endothelial cells
    • Tang, J.S.; Vissers, M.C.M.; Anderson, R.F.; Sreebhavan, S.; Bozonet, S.M.; Scheepens, A.; Melton, L.D. Bioavailable Blueberry-Derived Phenolic Acids at Physiological Concentrations Enhance Nrf2-Regulated Antioxidant Responses in Human Vascular Endothelial Cells. Mol. Nutr. Food Res. 2018, 62, 1700647. [CrossRef]
    • (2018) Mol. Nutr. Food Res. , vol.62 , pp. 1700647
    • Tang, J.S.1    Vissers, M.C.M.2    Anderson, R.F.3    Sreebhavan, S.4    Bozonet, S.M.5    Scheepens, A.6    Melton, L.D.7
  • 125
    • 84881641465 scopus 로고    scopus 로고
    • Flavonols enhanced production of anti-inflammatory substance(s) by Bifidobacterium adolescentis: Prebiotic actions of galangin, quercetin, and fisetin
    • CrossRef PubMed
    • Kawabata, K.; Sugiyama, Y.; Sakano, T.; Ohigashi, H. Flavonols enhanced production of anti-inflammatory substance(s) by Bifidobacterium adolescentis: Prebiotic actions of galangin, quercetin, and fisetin. BioFactors 2013, 39, 422–429. [CrossRef] [PubMed]
    • (2013) BioFactors , vol.39 , pp. 422-429
    • Kawabata, K.1    Sugiyama, Y.2    Sakano, T.3    Ohigashi, H.4
  • 126
    • 85042023348 scopus 로고    scopus 로고
    • 3-(4-Hydroxyphenyl)propionic acid, a major microbial metabolite of procyanidin A2, shows similar suppression of macrophage foam cell formation as its parent molecule
    • Zhang, Y.Y.; Li, X.L.; Li, T.Y.; Li, M.Y.; Huang, R.M.; Li, W.; Yang, R.L. 3-(4-Hydroxyphenyl)propionic acid, a major microbial metabolite of procyanidin A2, shows similar suppression of macrophage foam cell formation as its parent molecule. RSC Adv. 2018, 8, 6242–6250. [CrossRef]
    • (2018) RSC Adv , vol.8 , pp. 6242-6250
    • Zhang, Y.Y.1    Li, X.L.2    Li, T.Y.3    Li, M.Y.4    Huang, R.M.5    Li, W.6    Yang, R.L.7
  • 127
    • 70449085306 scopus 로고    scopus 로고
    • Urolithins, intestinal microbial metabolites of pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay
    • Dobroslawa, B.; Kasimsetty, S.G.; Khan, S.I.; Daneel, F. Urolithins, intestinal microbial metabolites of pomegranate ellagitannins, exhibit potent antioxidant activity in a cell-based assay. J. Agric. Food Chem. 2009, 57, 10181–10186. [CrossRef]
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 10181-10186
    • Dobroslawa, B.1    Kasimsetty, S.G.2    Khan, S.I.3    Daneel, F.4
  • 128
    • 77956196994 scopus 로고    scopus 로고
    • NF-κB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts
    • CrossRef PubMed
    • González-Sarrías, A.; Larrosa, M.; Toms-Barberán, F.A.; Dolara, P.; Espín, J.C. NF-κB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts. Br. J. Nutr. 2010, 104, 503–512. [CrossRef] [PubMed]
    • (2010) Br. J. Nutr. , vol.104 , pp. 503-512
    • González-Sarrías, A.1    Larrosa, M.2    Toms-Barberán, F.A.3    Dolara, P.4    Espín, J.C.5
  • 130
    • 84925511323 scopus 로고    scopus 로고
    • Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: A review
    • CrossRef PubMed
    • Duda-Chodak, A.; Tarko, T.; Satora, P.; Sroka, P. Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: A review. Eur. J. Nutr. 2015, 54, 325–341. [CrossRef] [PubMed]
    • (2015) Eur. J. Nutr. , vol.54 , pp. 325-341
    • Duda-Chodak, A.1    Tarko, T.2    Satora, P.3    Sroka, P.4
  • 131
    • 84924598047 scopus 로고    scopus 로고
    • Bioavailability of dietary polyphenols and gut microbiota metabolism: Antimicrobial properties
    • CrossRef PubMed
    • Marín, L.; Miguélez, E.M.; Villar, C.J.; Lombó, F. Bioavailability of dietary polyphenols and gut microbiota metabolism: Antimicrobial properties. Biomed Res. Int. 2015, 2015, 905215. [CrossRef] [PubMed]
    • (2015) Biomed Res. Int. , vol.2015 , pp. 905215
    • Marín, L.1    Miguélez, E.M.2    Villar, C.J.3    Lombó, F.4
  • 134
    • 70349325799 scopus 로고    scopus 로고
    • The effect of pomegranate (Punica granatum L.) byproducts and ellagitannins on the growth of human gut bacteria
    • Bialonska, D.; Kasimsetty, S.G.; Schrader, K.K.; Ferreira, D. The effect of pomegranate (Punica granatum L.) byproducts and ellagitannins on the growth of human gut bacteria. J. Agric. Food Chem. 2009, 57, 8344–8349. [CrossRef]
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 8344-8349
    • Bialonska, D.1    Kasimsetty, S.G.2    Schrader, K.K.3    Ferreira, D.4
  • 135
    • 77953122894 scopus 로고    scopus 로고
    • The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota
    • Bialonska, D.; Ramnani, P.; Kasimsetty, S.G.; Muntha, K.R.; Gibson, G.R.; Ferreira, D. The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota. Int. J. Food Microbiol. 2010, 140, 175–182. [CrossRef]
    • (2010) Int. J. Food Microbiol. , vol.140 , pp. 175-182
    • Bialonska, D.1    Ramnani, P.2    Kasimsetty, S.G.3    Muntha, K.R.4    Gibson, G.R.5    Ferreira, D.6
  • 136
    • 70350302911 scopus 로고    scopus 로고
    • Stimulatory role of grape pomace polyphenols on Lactobacillus acidophilus growth
    • CrossRef PubMed
    • Hervert-Hernández, D.; Pintado, C.; Rotger, R.; Goñi, I. Stimulatory role of grape pomace polyphenols on Lactobacillus acidophilus growth. Int. J. Food Microbiol. 2009, 136, 119–122. [CrossRef] [PubMed]
    • (2009) Int. J. Food Microbiol. , vol.136 , pp. 119-122
    • Hervert-Hernández, D.1    Pintado, C.2    Rotger, R.3    Goñi, I.4
  • 137
    • 85063071774 scopus 로고    scopus 로고
    • Prebiotic effect of predigested mango peel on gut microbiota assessed in a dynamic in vitro model of the human colon (TIM-2)
    • press. CrossRef
    • Sáyago-Ayerdi, S.G.; Zamora-Gasga, V.M.; Venema, K. Prebiotic effect of predigested mango peel on gut microbiota assessed in a dynamic in vitro model of the human colon (TIM-2). Food Res. Int. 2017, in press. [CrossRef]
    • (2017) Food Res. Int.
    • Sáyago-Ayerdi, S.G.1    Zamora-Gasga, V.M.2    Venema, K.3
  • 142
    • 85032257760 scopus 로고    scopus 로고
    • Effect of curcumin on the diversity of gut microbiota in ovariectomized rats
    • Zhang, Z.; Chen, Y.; Xiang, L.; Wang, Z.; Xiao, G.G.; Hu, J. Effect of curcumin on the diversity of gut microbiota in ovariectomized rats. Nutrients 2017, 9, 1146. [CrossRef]
    • (2017) Nutrients , vol.9 , pp. 1146
    • Zhang, Z.1    Chen, Y.2    Xiang, L.3    Wang, Z.4    Xiao, G.G.5    Hu, J.6
  • 143
    • 84901654102 scopus 로고    scopus 로고
    • Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity
    • Qiao, Y.; Sun, J.; Xia, S.; Tang, X.; Shi, Y.; Le, G. Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity. Food Funct. 2014, 5, 1241–1249. [CrossRef]
    • (2014) Food Funct , vol.5 , pp. 1241-1249
    • Qiao, Y.1    Sun, J.2    Xia, S.3    Tang, X.4    Shi, Y.5    Le, G.6
  • 144
    • 84965006890 scopus 로고    scopus 로고
    • Resveratrol attenuates trimethylamine-N-oxide (TMAO)-induced atherosclerosis by regulating TMAO synthesis and bile acid metabolism via remodeling of the gut microbiota
    • Chen, M.L.; Yi, L.; Zhang, Y.; Zhou, X.; Ran, L.; Yang, J.; Zhu, J.D.; Zhang, Q.Y.; Mi, M.T. Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota. MBio 2016, 7, e02210-15. [CrossRef]
    • (2016) MBio , vol.7 , pp. e02210-e02215
    • Chen, M.L.1    Yi, L.2    Zhang, Y.3    Zhou, X.4    Ran, L.5    Yang, J.6    Zhu, J.D.7    Zhang, Q.Y.8    Mi, M.T.9
  • 145
    • 85046650260 scopus 로고    scopus 로고
    • Metagenomics analysis of gut microbiota modulatory effect of green tea polyphenols by high fat diet-induced obesity mice model
    • Zhang, X.; Zhang, M.; Ho, C.T.; Guo, X.; Wu, Z.; Weng, P.; Yan, M.; Cao, J. Metagenomics analysis of gut microbiota modulatory effect of green tea polyphenols by high fat diet-induced obesity mice model. J. Funct. Foods 2018, 46, 268–277. [CrossRef]
    • (2018) J. Funct. Foods , vol.46 , pp. 268-277
    • Zhang, X.1    Zhang, M.2    Ho, C.T.3    Guo, X.4    Wu, Z.5    Weng, P.6    Yan, M.7    Cao, J.8
  • 146
    • 85041719930 scopus 로고    scopus 로고
    • Green tea polyphenols modulate colonic microbiota diversity and lipid metabolism in high-fat diet treated HfA mice
    • CrossRef PubMed
    • Wang, L.; Zeng, B.; Liu, Z.; Liao, Z.; Zhong, Q.; Gu, L.; Wei, H.; Fang, X. Green Tea Polyphenols Modulate Colonic Microbiota Diversity and Lipid Metabolism in High-Fat Diet Treated HFA Mice. J. Food Sci. 2018, 83, 864–873. [CrossRef] [PubMed]
    • (2018) J. Food Sci. , vol.83 , pp. 864-873
    • Wang, L.1    Zeng, B.2    Liu, Z.3    Liao, Z.4    Zhong, Q.5    Gu, L.6    Wei, H.7    Fang, X.8
  • 147
    • 5444248493 scopus 로고    scopus 로고
    • Akkermansia municiphila gen. Nov., sp. Nov., a human intestinal mucin-degrading bacterium
    • Derrien, M.; Vaughan, E.E.; Plugge, C.M.; de Vos, W.M. Akkermansia municiphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. Int. J. Syst. Evol. Microbiol. 2004, 54, 1469–1476. [CrossRef]
    • (2004) Int. J. Syst. Evol. Microbiol. , vol.54 , pp. 1469-1476
    • Derrien, M.1    Vaughan, E.E.2    Plugge, C.M.3    De Vos, W.M.4
  • 148
    • 84997701899 scopus 로고    scopus 로고
    • A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice
    • CrossRef PubMed
    • Plovier, H.; Everard, A.; Druart, C.; Depommier, C.; Van Hul, M.; Geurts, L.; Chilloux, J.; Ottman, N.; Duparc, T.; Lichtenstein, L.; et al. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nat. Med. 2017, 23, 107–113. [CrossRef] [PubMed]
    • (2017) Nat. Med. , vol.23 , pp. 107-113
    • Plovier, H.1    Everard, A.2    Druart, C.3    Depommier, C.4    Van Hul, M.5    Geurts, L.6    Chilloux, J.7    Ottman, N.8    Duparc, T.9    Lichtenstein, L.10
  • 149
    • 84947460237 scopus 로고    scopus 로고
    • Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice
    • CrossRef PubMed
    • Schneeberger, M.; Everard, A.; Gómez-Valadés, A.G.; Matamoros, S.; Ramírez, S.; Delzenne, N.M.; Gomis, R.; Claret, M.; Cani, P.D. Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice. Sci. Rep. 2015, 5, 16643. [CrossRef] [PubMed]
    • (2015) Sci. Rep. , vol.5 , pp. 16643
    • Schneeberger, M.1    Everard, A.2    Gómez-Valadés, A.G.3    Matamoros, S.4    Ramírez, S.5    Delzenne, N.M.6    Gomis, R.7    Claret, M.8    Cani, P.D.9
  • 150
    • 85008192260 scopus 로고    scopus 로고
    • Metformin is associated with higher relative abundance of mucin-degrading Akkermansia muciniphila and several short-chain fatty acid-producing microbiota in the gut
    • CrossRef PubMed
    • De La Cuesta-Zuluaga, J.; Mueller, N.T.; Corrales-Agudelo, V.; Velásquez-Mejía, E.P.; Carmona, J.A.; Abad, J.M.; Escobar, J.S. Metformin is associated with higher relative abundance of mucin-degrading Akkermansia muciniphila and several short-chain fatty acid-producing microbiota in the gut. Diabetes Care 2017, 40, 54–62. [CrossRef] [PubMed]
    • (2017) Diabetes Care , vol.40 , pp. 54-62
    • De La Cuesta-Zuluaga, J.1    Mueller, N.T.2    Corrales-Agudelo, V.3    Velásquez-Mejía, E.P.4    Carmona, J.A.5    Abad, J.M.6    Escobar, J.S.7
  • 151
    • 0033950802 scopus 로고    scopus 로고
    • Survival and therapeutic potential of probiotic organisms with reference to Lactobacillus acidophilus and Bifidobacterium spp
    • CrossRef PubMed
    • Kailasapathy, K.; Chin, J. Survival and therapeutic potential of probiotic organisms with reference to Lactobacillus acidophilus and Bifidobacterium spp. Immunol. Cell Biol. 2000, 78, 80–88. [CrossRef] [PubMed]
    • (2000) Immunol. Cell Biol. , vol.78 , pp. 80-88
    • Kailasapathy, K.1    Chin, J.2
  • 153
    • 85020401269 scopus 로고    scopus 로고
    • Effect of apple extracts and selective polyphenols on the adhesion of potential probiotic strains of Lactobacillus gasseri R and Lactobacillus casei FMP
    • Volstatova, T.; Marsik, P.; Rada, V.; Geigerova, M.; Havlik, J. Effect of apple extracts and selective polyphenols on the adhesion of potential probiotic strains of Lactobacillus gasseri R and Lactobacillus casei FMP. J. Funct. Foods 2017, 35, 391–397. [CrossRef]
    • (2017) J. Funct. Foods , vol.35 , pp. 391-397
    • Volstatova, T.1    Marsik, P.2    Rada, V.3    Geigerova, M.4    Havlik, J.5
  • 154
    • 84971519476 scopus 로고    scopus 로고
    • From dietary fiber to host physiology: Short-chain fatty acids as key bacterial metabolites
    • Koh, A.; De Vadder, F.; Kovatcheva-Datchary, P.; Bäckhed, F. From dietary fiber to host physiology: Short-chain fatty acids as key bacterial metabolites. Cell 2016, 165, 1332–1345. [CrossRef]
    • (2016) Cell , vol.165 , pp. 1332-1345
    • Koh, A.1    De Vadder, F.2    Kovatcheva-Datchary, P.3    Bäckhed, F.4
  • 156
    • 33747170602 scopus 로고    scopus 로고
    • Cecal parameters of rats fed diets containing grapefruit polyphenols and inulin as single supplements or in a combination
    • CrossRef PubMed
    • Zdunczyk, ´ Z.; Juskiewicz, J.; Estrella, I. Cecal parameters of rats fed diets containing grapefruit polyphenols and inulin as single supplements or in a combination. Nutrition 2006, 22, 898–904. [CrossRef] [PubMed]
    • (2006) Nutrition , vol.22 , pp. 898-904
    • Zdunczyk, Z.1    Juskiewicz, J.2    Estrella, I.3
  • 157
    • 0038314499 scopus 로고    scopus 로고
    • Apple pectin and a polyphenol-rich apple concentrate are more effective together than separately on cecal fermentations and plasma lipids in rats
    • CrossRef PubMed
    • Aprikian, O.; Duclos, V.; Guyot, S.; Besson, C.; Manach, C.; Bernalier, A.; Morand, C.; Rémésy, C.; Demigné, C. Apple Pectin and a Polyphenol-Rich Apple Concentrate Are More Effective Together Than Separately on Cecal Fermentations and Plasma Lipids in Rats. J. Nutr. 2003, 133, 1860–1865. [CrossRef] [PubMed]
    • (2003) J. Nutr. , vol.133 , pp. 1860-1865
    • Aprikian, O.1    Duclos, V.2    Guyot, S.3    Besson, C.4    Manach, C.5    Bernalier, A.6    Morand, C.7    Rémésy, C.8    Demigné, C.9
  • 158
    • 84903291718 scopus 로고    scopus 로고
    • Strawberry ellagitannins thwarted the positive effects of dietary fructooligosaccharides in rat cecum
    • CrossRef PubMed
    • Fotschki, B.; Milala, J.; Jurgonski, A.; Karlinska, E.; Zdunczyk, Z.; Juskiewicz, J. Strawberry ellagitannins thwarted the positive effects of dietary fructooligosaccharides in rat cecum. J. Agric. Food Chem. 2014, 62, 5871–5880. [CrossRef] [PubMed]
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 5871-5880
    • Fotschki, B.1    Milala, J.2    Jurgonski, A.3    Karlinska, E.4    Zdunczyk, Z.5    Juskiewicz, J.6
  • 159
    • 84978670440 scopus 로고    scopus 로고
    • Anthocyanins in strawberry polyphenolic extract enhance the beneficial effects of diets with fructooligosaccharides in the rat cecal environment
    • Fotschki, B.; Juskiewicz, J.; Jurgonski, ´ A.; Kołodziejczyk, K.; Milala, J.; Kosmala, M.; Zdunczyk, ´ Z. Anthocyanins in strawberry polyphenolic extract enhance the beneficial effects of diets with fructooligosaccharides in the rat cecal environment. PLoS ONE 2016, 11, e0149081. [CrossRef]
    • (2016) PLoS ONE , vol.11 , pp. e0149081
    • Fotschki, B.1    Juskiewicz, J.2    Jurgonski, A.3    Kołodziejczyk, K.4    Milala, J.5    Kosmala, M.6    Zdunczyk, Z.7
  • 161
    • 2442655096 scopus 로고    scopus 로고
    • Lactic acid bacteria secrete metabolites retaining anti-inflammatory properties after intestinal transport
    • CrossRef PubMed
    • Ménard, S.; Candalh, C.; Bambou, J.C.; Terpend, K.; Cerf-Bensussan, N.; Heyman, M. Lactic acid bacteria secrete metabolites retaining anti-inflammatory properties after intestinal transport. Gut 2004, 53, 821–828. [CrossRef] [PubMed]
    • (2004) Gut , vol.53 , pp. 821-828
    • Ménard, S.1    Candalh, C.2    Bambou, J.C.3    Terpend, K.4    Cerf-Bensussan, N.5    Heyman, M.6
  • 163
    • 47849097120 scopus 로고    scopus 로고
    • Anti-inflammatory activity of probiotic Bifidobacterium: Enhancement of IL-10 production in peripheral blood mononuclear cells from ulcerative colitis patients and inhibition of IL-8 secretion in HT-29 cells
    • Imaoka, A.; Shima, T.; Kato, K.; Mizuno, S.; Uehara, T.; Matsumoto, S.; Setoyana, H.; Hara, T.; Umesaki, Y. Anti-inflammatory activity of probiotic Bifidobacterium: Enhancement of IL-10 production in peripheral blood mononuclear cells from ulcerative colitis patients and inhibition of IL-8 secretion in HT-29 cells. World J. Gastroenterol. 2008, 14, 2511–2516. [CrossRef]
    • (2008) World J. Gastroenterol. , vol.14 , pp. 2511-2516
    • Imaoka, A.1    Shima, T.2    Kato, K.3    Mizuno, S.4    Uehara, T.5    Matsumoto, S.6    Setoyana, H.7    Hara, T.8    Umesaki, Y.9
  • 165
    • 85056590725 scopus 로고    scopus 로고
    • The gut microbiota at the intersection of diet and human health
    • CrossRef PubMed
    • Gentile, C.L.; Weir, T.L. The gut microbiota at the intersection of diet and human health. Science 2018, 362, 776–780. [CrossRef] [PubMed]
    • (2018) Science , vol.362 , pp. 776-780
    • Gentile, C.L.1    Weir, T.L.2
  • 166
    • 85022068358 scopus 로고    scopus 로고
    • Gut microbiome, metabolome, and allergic diseases
    • CrossRef PubMed
    • Hirata, S.; Kunisawa, J. Gut microbiome, metabolome, and allergic diseases. Allergol. Int. 2017, 66, 523–528. [CrossRef] [PubMed]
    • (2017) Allergol. Int. , vol.66 , pp. 523-528
    • Hirata, S.1    Kunisawa, J.2
  • 167
    • 85033784875 scopus 로고    scopus 로고
    • Dietary and microbial metabolites in the regulation of host immunity
    • CrossRef PubMed
    • Shibata, N.; Kunisawa, J.; Kiyono, H. Dietary and microbial metabolites in the regulation of host immunity. Front. Microbiol. 2017, 8, 2171. [CrossRef] [PubMed]
    • (2017) Front. Microbiol. , vol.8 , pp. 2171
    • Shibata, N.1    Kunisawa, J.2    Kiyono, H.3
  • 168
    • 4043161248 scopus 로고    scopus 로고
    • Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice
    • CrossRef PubMed
    • Sudo, N.; Chida, Y.; Aiba, Y.; Sonoda, J.; Oyama, N.; Yu, X.N.; Kubo, C.; Koga, Y. Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J. Physiol. 2004, 558, 263–275. [CrossRef] [PubMed]
    • (2004) J. Physiol. , vol.558 , pp. 263-275
    • Sudo, N.1    Chida, Y.2    Aiba, Y.3    Sonoda, J.4    Oyama, N.5    Yu, X.N.6    Kubo, C.7    Koga, Y.8


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