메뉴 건너뛰기




Volumn 407, Issue 7, 2015, Pages 1885-1899

Highly sensitive analysis of polyphenols and their metabolites in human blood cells using dispersive SPE extraction and LC-MS/MS

Author keywords

Human; Metabolism; Pine bark; Procyanidins; QuEChERS

Indexed keywords

BIOMOLECULES; CELLS; CYTOLOGY; ENZYMATIC HYDROLYSIS; EXTRACTION; FLAVONOIDS; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; METABOLISM; METABOLITES; ORGANIC COMPOUNDS; PHARMACOKINETICS; PHASE SEPARATION; PHENOLS;

EID: 84928647961     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-8451-y     Document Type: Article
Times cited : (24)

References (36)
  • 1
    • 33748305800 scopus 로고    scopus 로고
    • Single and multiple dose pharmacokinetics of maritime pine bark extract (pycnogenol) after oral administration to healthy volunteers
    • 10.1186/1472-6904-6-4
    • Grimm T, Skrabala R, Chovanova Z, Muchova J, Sumegova K, Liptakova A, Durackova Z, Högger P (2006) Single and multiple dose pharmacokinetics of maritime pine bark extract (pycnogenol) after oral administration to healthy volunteers. BMC Clin Pharmacol 6:4. doi: 10.1186/1472-6904-6-4
    • (2006) BMC Clin Pharmacol , vol.6 , pp. 4
    • Grimm, T.1    Skrabala, R.2    Chovanova, Z.3    Muchova, J.4    Sumegova, K.5    Liptakova, A.6    Durackova, Z.7    Högger, P.8
  • 2
    • 79951609639 scopus 로고    scopus 로고
    • Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites
    • 10.1039/c0fo00132e 1:CAS:528:DC%2BC3MXktVSisA%3D%3D
    • Monagas M, Urpi-Sarda M, Sanchez-Patan F, Llorach R, Garrido I, Gomez-Cordoves C, Andres-Lacueva C, Bartolome B (2010) Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites. Food Funct 1(3):233-253. doi: 10.1039/c0fo00132e
    • (2010) Food Funct , vol.1 , Issue.3 , pp. 233-253
    • Monagas, M.1    Urpi-Sarda, M.2    Sanchez-Patan, F.3    Llorach, R.4    Garrido, I.5    Gomez-Cordoves, C.6    Andres-Lacueva, C.7    Bartolome, B.8
  • 3
    • 1342328148 scopus 로고    scopus 로고
    • Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol)
    • 1:CAS:528:DC%2BD2cXhsFWku7o%3D
    • Grimm T, Schäfer A, Högger P (2004) Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol). Free Radic Biol Med 36(6):811-822
    • (2004) Free Radic Biol Med , vol.36 , Issue.6 , pp. 811-822
    • Grimm, T.1    Schäfer, A.2    Högger, P.3
  • 4
    • 0036219486 scopus 로고    scopus 로고
    • A review of the French maritime pine bark extract (Pycnogenol), a herbal medication with a diverse clinical pharmacology
    • 1:CAS:528:DC%2BD38Xkt1Grs7o%3D
    • Rohdewald P (2002) A review of the French maritime pine bark extract (Pycnogenol), a herbal medication with a diverse clinical pharmacology. Int J Clin Pharmacol Ther 40:158-168
    • (2002) Int J Clin Pharmacol Ther , vol.40 , pp. 158-168
    • Rohdewald, P.1
  • 5
    • 78651397865 scopus 로고    scopus 로고
    • A review on biological, nutraceutical and clinical aspects of French maritime pine bark extract
    • 10.1016/j.jep.2010.10.041
    • Maimoona A, Naeem I, Saddiqe Z, Jameel K (2011) A review on biological, nutraceutical and clinical aspects of French maritime pine bark extract. J Ethnopharmacol 133(2):261-277. doi: 10.1016/j.jep.2010.10.041
    • (2011) J Ethnopharmacol , vol.133 , Issue.2 , pp. 261-277
    • Maimoona, A.1    Naeem, I.2    Saddiqe, Z.3    Jameel, K.4
  • 6
    • 84862287505 scopus 로고    scopus 로고
    • Facilitated cellular uptake and suppression of inducible nitric oxide synthase by a metabolite of maritime pine bark extract (Pycnogenol)
    • 10.1016/j.freeradbiomed.2012.04.013 1:CAS:528:DC%2BC38XpvVOlsbs%3D
    • Uhlenhut K, Högger P (2012) Facilitated cellular uptake and suppression of inducible nitric oxide synthase by a metabolite of maritime pine bark extract (Pycnogenol). Free Radic Biol Med 53(2):305-313. doi: 10.1016/j.freeradbiomed.2012.04.013
    • (2012) Free Radic Biol Med , vol.53 , Issue.2 , pp. 305-313
    • Uhlenhut, K.1    Högger, P.2
  • 7
    • 84876953809 scopus 로고    scopus 로고
    • Facilitated uptake of a bioactive metabolite of maritime pine bark extract (Pycnogenol) into human erythrocytes
    • 10.1371/journal.pone.0063197 1:CAS:528:DC%2BC3sXnsFWrtbk%3D
    • Kurlbaum M, Mülek M, Högger P (2013) Facilitated uptake of a bioactive metabolite of maritime pine bark extract (Pycnogenol) into human erythrocytes. PLoS One 8(4):e63197. doi: 10.1371/journal.pone.0063197
    • (2013) PLoS One , vol.8 , Issue.4 , pp. e63197
    • Kurlbaum, M.1    Mülek, M.2    Högger, P.3
  • 8
    • 77957315722 scopus 로고    scopus 로고
    • Determination of quercetin and resveratrol in whole blood - Implications for bioavailability studies
    • 1:CAS:528:DC%2BC3cXht1CksbjO
    • Biasutto L, Marotta E, Hgarbisa S, Zoratti M, Paradisi C (2010) Determination of quercetin and resveratrol in whole blood - implications for bioavailability studies. Molecules 15:6570-6579
    • (2010) Molecules , vol.15 , pp. 6570-6579
    • Biasutto, L.1    Marotta, E.2    Hgarbisa, S.3    Zoratti, M.4    Paradisi, C.5
  • 9
    • 0037359650 scopus 로고    scopus 로고
    • Fast and easy multiresidue method employing acetonitrile extraction/partitioning and "dispersive solid-phase extraction" for the determination of pesticide residues in produce
    • 1:CAS:528:DC%2BD3sXivFOjsLc%3D
    • Anastassiades M, Lehotay SJ, Stajnbaher D, Schenck FJ (2003) Fast and easy multiresidue method employing acetonitrile extraction/partitioning and "dispersive solid-phase extraction" for the determination of pesticide residues in produce. J AOAC Int 86(2):412-431
    • (2003) J AOAC Int , vol.86 , Issue.2 , pp. 412-431
    • Anastassiades, M.1    Lehotay, S.J.2    Stajnbaher, D.3    Schenck, F.J.4
  • 10
    • 34250304405 scopus 로고    scopus 로고
    • Determination of pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulfate: Collaborative study
    • 1:CAS:528:DC%2BD2sXksFWjsb8%3D
    • Lehotay SJ (2007) Determination of pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulfate: collaborative study. J AOAC Int 90(2):485-520
    • (2007) J AOAC Int , vol.90 , Issue.2 , pp. 485-520
    • Lehotay, S.J.1
  • 11
    • 77950042977 scopus 로고    scopus 로고
    • Comparison of QuEChERS sample preparation methods for the analysis of pesticide residues in fruits and vegetables
    • 10.1016/j.chroma.2010.01.044 1:CAS:528:DC%2BC3cXktVWksL4%3D
    • Lehotay SJ, Son KA, Kwon H, Koesukwiwat U, Fu W, Mastovska K, Hoh E, Leepipatpiboon N (2010) Comparison of QuEChERS sample preparation methods for the analysis of pesticide residues in fruits and vegetables. J Chromatogr A 1217(16):2548-2560. doi: 10.1016/j.chroma.2010.01.044
    • (2010) J Chromatogr A , vol.1217 , Issue.16 , pp. 2548-2560
    • Lehotay, S.J.1    Son, K.A.2    Kwon, H.3    Koesukwiwat, U.4    Fu, W.5    Mastovska, K.6    Hoh, E.7    Leepipatpiboon, N.8
  • 12
    • 36849079273 scopus 로고    scopus 로고
    • Analysis of pesticide residues in fruit and vegetables with ethyl acetate extraction using gas and liquid chromatography with tandem mass spectrometric detection
    • 10.1007/s00216-007-1425-6
    • Pihlström T, Blomkvist G, Friman P, Pagard U, Österdahl BG (2007) Analysis of pesticide residues in fruit and vegetables with ethyl acetate extraction using gas and liquid chromatography with tandem mass spectrometric detection. Anal Bioanal Chem 389(6):1773-1789. doi: 10.1007/s00216-007-1425-6
    • (2007) Anal Bioanal Chem , vol.389 , Issue.6 , pp. 1773-1789
    • Pihlström, T.1    Blomkvist, G.2    Friman, P.3    Pagard, U.4    Österdahl, B.G.5
  • 15
    • 33750364721 scopus 로고    scopus 로고
    • Multiresidue analytical method using dispersive solid-phase extraction and gas chromatography/ion trap mass spectrometry to determine pharmaceuticals in whole blood
    • 10.1016/j.chroma.2006.09.033
    • Plossl F, Giera M, Bracher F (2006) Multiresidue analytical method using dispersive solid-phase extraction and gas chromatography/ion trap mass spectrometry to determine pharmaceuticals in whole blood. J Chromatogr A 1135(1):19-26. doi: 10.1016/j.chroma.2006.09.033
    • (2006) J Chromatogr A , vol.1135 , Issue.1 , pp. 19-26
    • Plossl, F.1    Giera, M.2    Bracher, F.3
  • 16
    • 77955898553 scopus 로고    scopus 로고
    • Analysis of multiple anticoagulant rodenticides in animal blood and liver tissue using principles of QuEChERS method
    • 1:CAS:528:DC%2BC3cXmslGgsbc%3D
    • Vudathala D, Cummings M, Murphy L (2010) Analysis of multiple anticoagulant rodenticides in animal blood and liver tissue using principles of QuEChERS method. J Anal Toxicol 34:273-279
    • (2010) J Anal Toxicol , vol.34 , pp. 273-279
    • Vudathala, D.1    Cummings, M.2    Murphy, L.3
  • 17
    • 84866513354 scopus 로고    scopus 로고
    • Rapid drug extraction from human whole blood using a modified QuEChERS extraction method
    • 10.1016/j.legalmed.2012.04.008 1:CAS:528:DC%2BC38XhsVSmsb%2FO
    • Usui K, Hayashizaki Y, Hashiyada M, Funayama M (2012) Rapid drug extraction from human whole blood using a modified QuEChERS extraction method. Leg Med (Tokyo) 14(6):286-296. doi: 10.1016/j.legalmed.2012.04.008
    • (2012) Leg Med (Tokyo) , vol.14 , Issue.6 , pp. 286-296
    • Usui, K.1    Hayashizaki, Y.2    Hashiyada, M.3    Funayama, M.4
  • 18
    • 84866513352 scopus 로고    scopus 로고
    • Rapid determination of disulfoton and its oxidative metabolites in human whole blood and urine using QuEChERS extraction and liquid chromatography-tandem mass spectrometry
    • 10.1016/j.legalmed.2012.06.005 1:CAS:528:DC%2BC38XhsVSmsb%2FF
    • Usui K, Hayashizaki Y, Minagawa T, Hashiyada M, Nakano A, Funayama M (2012) Rapid determination of disulfoton and its oxidative metabolites in human whole blood and urine using QuEChERS extraction and liquid chromatography-tandem mass spectrometry. Leg Med (Tokyo) 14(6):309-316. doi: 10.1016/j.legalmed.2012.06.005
    • (2012) Leg Med (Tokyo) , vol.14 , Issue.6 , pp. 309-316
    • Usui, K.1    Hayashizaki, Y.2    Minagawa, T.3    Hashiyada, M.4    Nakano, A.5    Funayama, M.6
  • 19
    • 84881110984 scopus 로고    scopus 로고
    • Development of a simple one-pot extraction method for various drugs and metabolites of forensic interest in blood by modifying the QuEChERS method
    • 10.1016/j.forsciint.2013.06.015 1:CAS:528:DC%2BC3sXhsVylsLjK
    • Matsuta S, Nakanishi K, Miki A, Zaitsu K, Shima N, Kamata T, Nishioka H, Katagi M, Tatsuno M, Tsuboi K, Tsuchihashi H, Suzuki K (2013) Development of a simple one-pot extraction method for various drugs and metabolites of forensic interest in blood by modifying the QuEChERS method. Forensic Sci Int 232(1-3):40-45. doi: 10.1016/j.forsciint.2013.06.015
    • (2013) Forensic Sci Int , vol.232 , Issue.1-3 , pp. 40-45
    • Matsuta, S.1    Nakanishi, K.2    Miki, A.3    Zaitsu, K.4    Shima, N.5    Kamata, T.6    Nishioka, H.7    Katagi, M.8    Tatsuno, M.9    Tsuboi, K.10    Tsuchihashi, H.11    Suzuki, K.12
  • 20
    • 84901927912 scopus 로고    scopus 로고
    • Cleaning up blood samples using a modified "QuEChERS" procedure for the determination of drugs of abuse and benzodiazepines by UPLC-MSMS
    • 10.1016/j.forsciint.2014.05.005
    • Anzillotti L, Odoardi S, Strano-Rossi S (2014) Cleaning up blood samples using a modified "QuEChERS" procedure for the determination of drugs of abuse and benzodiazepines by UPLC-MSMS. Forensic Sci Int 243C:99-106. doi: 10.1016/j.forsciint.2014.05.005
    • (2014) Forensic Sci Int , vol.243 C , pp. 99-106
    • Anzillotti, L.1    Odoardi, S.2    Strano-Rossi, S.3
  • 21
    • 0037663202 scopus 로고    scopus 로고
    • Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS
    • 1:CAS:528:DC%2BD3sXltV2jsL8%3D
    • Matuszewski BK, Constanzer L, Chavez-Eng M (2003) Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal Chem 75:3019-3030
    • (2003) Anal Chem , vol.75 , pp. 3019-3030
    • Matuszewski, B.K.1    Constanzer, L.2    Chavez-Eng, M.3
  • 22
    • 34249721558 scopus 로고    scopus 로고
    • Systematic and comprehensive strategy for reducing matrix effects in LC/MS/MS analyses
    • 10.1016/j.jchromb.2006.12.030 1:CAS:528:DC%2BD2sXmtVGmsrs%3D
    • Chambers E, Wagrowski-Diehl DM, Lu Z, Mazzeo JR (2007) Systematic and comprehensive strategy for reducing matrix effects in LC/MS/MS analyses. J Chromatogr B Anal Technol Biomed Life Sci 852(1-2):22-34. doi: 10.1016/j.jchromb.2006.12.030
    • (2007) J Chromatogr B Anal Technol Biomed Life Sci , vol.852 , Issue.1-2 , pp. 22-34
    • Chambers, E.1    Wagrowski-Diehl, D.M.2    Lu, Z.3    Mazzeo, J.R.4
  • 26
    • 42649108388 scopus 로고    scopus 로고
    • Absolute quantification of cardiac troponin T by means of liquid chromatography/triple quadrupole tandem mass spectrometry
    • 10.1002/rcm.3495 1:CAS:528:DC%2BD1cXltlCjt74%3D
    • Cavaliere C, Cucci F, Guarino C, Gubbiotti R, Samperi R, Lagana A (2008) Absolute quantification of cardiac troponin T by means of liquid chromatography/triple quadrupole tandem mass spectrometry. Rapid Commun Mass Spectrom 22(8):1159-1167. doi: 10.1002/rcm.3495
    • (2008) Rapid Commun Mass Spectrom , vol.22 , Issue.8 , pp. 1159-1167
    • Cavaliere, C.1    Cucci, F.2    Guarino, C.3    Gubbiotti, R.4    Samperi, R.5    Lagana, A.6
  • 27
    • 58149183250 scopus 로고    scopus 로고
    • Rapid-resolution liquid chromatography/mass spectrometry for determination and quantitation of polyphenols in grape berries
    • 10.1002/rcm.3705 1:CAS:528:DC%2BD1cXhtleiu77J
    • Cavaliere C, Foglia P, Gubbiotti R, Sacchetti P, Samperi R, Lagana A (2008) Rapid-resolution liquid chromatography/mass spectrometry for determination and quantitation of polyphenols in grape berries. Rapid Commun Mass Spectrom 22(20):3089-3099. doi: 10.1002/rcm.3705
    • (2008) Rapid Commun Mass Spectrom , vol.22 , Issue.20 , pp. 3089-3099
    • Cavaliere, C.1    Foglia, P.2    Gubbiotti, R.3    Sacchetti, P.4    Samperi, R.5    Lagana, A.6
  • 28
    • 0029658249 scopus 로고    scopus 로고
    • Erythrocytes and the transport of drugs and endogenous compounds
    • 1:CAS:528:DyaK28Xht1Oktbc%3D
    • Highley MS, De Bruijn EA (1996) Erythrocytes and the transport of drugs and endogenous compounds. Pharm Res 13(2):186-195
    • (1996) Pharm Res , vol.13 , Issue.2 , pp. 186-195
    • Highley, M.S.1    De Bruijn, E.A.2
  • 29
    • 0030770275 scopus 로고    scopus 로고
    • Red blood cells: A neglected compartment in pharmacokinetics and pharmacodynamics
    • 1:CAS:528:DyaK2sXmtl2hsbs%3D
    • Hinderling PH (1997) Red blood cells: a neglected compartment in pharmacokinetics and pharmacodynamics. Pharmacol Rev 49:279-295
    • (1997) Pharmacol Rev , vol.49 , pp. 279-295
    • Hinderling, P.H.1
  • 30
    • 0027174992 scopus 로고
    • Cyclosporin clinical pharmacokinetics
    • 10.2165/00003088-199324060-00004 1:STN:280:DyaK3s3pt1aktw%3D%3D
    • Fahr A (1993) Cyclosporin clinical pharmacokinetics. Clin Pharmacokinet 24(6):472-495. doi: 10.2165/00003088-199324060-00004
    • (1993) Clin Pharmacokinet , vol.24 , Issue.6 , pp. 472-495
    • Fahr, A.1
  • 31
    • 0023567976 scopus 로고
    • Kinetics of methotrexate and its metabolites in red blood cells
    • 10.1089/cdd.1987.4.119 1:CAS:528:DyaL1cXjtFamuw%3D%3D
    • Lena N, Imbert AM, Brunet P, Cano JP, Carcassonne Y (1987) Kinetics of methotrexate and its metabolites in red blood cells. Cancer Drug Deliv 4(2):119-127. doi: 10.1089/cdd.1987.4.119
    • (1987) Cancer Drug Deliv , vol.4 , Issue.2 , pp. 119-127
    • Lena, N.1    Imbert, A.M.2    Brunet, P.3    Cano, J.P.4    Carcassonne, Y.5
  • 32
    • 0037347482 scopus 로고    scopus 로고
    • Measurement of metformin concentration in erythrocytes: Clinical implications
    • 1:CAS:528:DC%2BD3sXivVCjs7g%3D
    • Lalau JD, Lacroix C (2003) Measurement of metformin concentration in erythrocytes: clinical implications. Diabetes Obes Metab 5:93-98
    • (2003) Diabetes Obes Metab , vol.5 , pp. 93-98
    • Lalau, J.D.1    Lacroix, C.2
  • 34
    • 0037420211 scopus 로고    scopus 로고
    • Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography-tandem mass spectrometry
    • 1:CAS:528:DC%2BD3sXmtVaksbc%3D
    • Polson C, Sarkar P, Incledon B, Raguvaran V, Grant R (2003) Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography-tandem mass spectrometry. J Chromatogr B Anal Technol Biomed Life Sci 785(2):263-275
    • (2003) J Chromatogr B Anal Technol Biomed Life Sci , vol.785 , Issue.2 , pp. 263-275
    • Polson, C.1    Sarkar, P.2    Incledon, B.3    Raguvaran, V.4    Grant, R.5
  • 35
    • 34250304405 scopus 로고    scopus 로고
    • Pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulfate
    • AOAC Official Method 2007.01
    • AOAC Official Method 2007.01 (2007) Pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulfate. J AOAC Int 90:485
    • (2007) J AOAC Int , vol.90 , pp. 485
  • 36
    • 84896357341 scopus 로고    scopus 로고
    • Nutrition-derived bioactive metabolites produced by gut microbiota and their potential impact on human health
    • Högger P (2013) Nutrition-derived bioactive metabolites produced by gut microbiota and their potential impact on human health. NUME 1:1
    • (2013) NUME , vol.1 , pp. 1
    • Högger, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.