Interpreting microbial biosynthesis in the genomic age: Biological and practical considerations

Marine Drugs

Volumn 15, Issue 6, 2017, Pages

  Miller, Ian J ^a   Chevrette, Marc G ^a   Kwan, Jason C ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Binning; Bioinformatics; Biosynthesis; Biosynthetic gene clusters; Genome mining; Genome sequencing; Metagenomics; Secondary metabolism

Indexed keywords

AMINOGLYCOSIDE; CONTIG; BIOLOGICAL PRODUCT;

ACCURACY; ALGORITHM; BACTERIAL GENE; BACTERIAL GENOME; BIOINFORMATICS; BIOSYNTHESIS; BIOSYNTHETIC GENE CLUSTER; CHEMICAL ANALYSIS; COMPUTER SIMULATION; DE NOVO ASSEMBLY; ENZYME SPECIFICITY; FUNCTIONAL METAGENOMICS; GENE CLUSTER; GENE SEQUENCE; GENETIC HETEROGENEITY; GENOME MINING; GENOMIC AGE; GENOMICS; MARINE BACTERIUM; METAGENOMIC BINNING; METAGENOMICS; MICROBIAL BIOSYNTHESIS; MICROBIAL DIVERSITY; MICROBIAL METABOLISM; MICROBIOLOGICAL PHENOMENA AND FUNCTIONS; MOLECULAR EVOLUTION; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; POLYMERASE CHAIN REACTION; PREDICTION; PRODUCT STRUCTURE PREDICTION; REVIEW; SALINISPORA TROPICA; SECONDARY METABOLISM; SHOTGUN SEQUENCING TECHNOLOGY; SLM GENE; BIOLOGY; DRUG DEVELOPMENT; GENETICS; METABOLISM; MICROMONOSPORACEAE; MULTIGENE FAMILY; PROCEDURES;

BIOLOGICAL PRODUCTS; COMPUTATIONAL BIOLOGY; DRUG DISCOVERY; GENOME, BACTERIAL; GENOMICS; METAGENOMICS; MICROMONOSPORACEAE; MULTIGENE FAMILY;

EID: 85020798913     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md15060165     Document Type: Review

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