Detection of low-abundance bacterial strains in metagenomic datasets by eigengenome partitioning

Nature Biotechnology

Volumn 33, Issue 10, 2015, Pages 1053-1060

  Cleary, Brian ^a,b   Brito, Ilana Lauren ^a,b,c   Huang, Katherine ^b   Gevers, Dirk ^b   Shea, Terrance ^b   Young, Sarah ^b   Alm, Eric J ^b,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RANDOM ACCESS STORAGE;

BACTERIAL STRAINS; BACTERIAL TAXA; COMMODITY HARDWARE; COMPLETE GENOMES; MICROBIAL GENOMES; RELATIVE ABUNDANCE; STRAIN ANALYSIS;

GENES;

CONTIG;

ALGORITHM; ANALYTIC METHOD; ARTICLE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTEROIDACEAE; BIFIDOBACTERIACEAE; BRACHYSPIRACEAE; CALCULATION; CLOSTRIDIACEAE; CONTROLLED STUDY; CORIOBACTERIACEAE; DNA BASE COMPOSITION; EIGENGENOME PARTITIONING; ENTEROBACTERIACEAE; EUBACTERIACEAE; GENOME ANALYSIS; INTERMETHOD COMPARISON; LACHNOSPIRACEAE; LATENT STRAIN ANALYSIS; MEASUREMENT ACCURACY; METAGENOMICS; NATURAL LANGUAGE PROCESSING; NONHUMAN; PEPTOSTREPTOCOCCACEAE; PREVOTELLACEAE; PRIORITY JOURNAL; RIKENELLACEAE; RUMINOCOCCACEAE; SALMONELLA; SEQUENCE ALIGNMENT; SPIROCHAETECEAE; STREPTOCOCCACEAE; VEIONELLACEAE; BACTERIUM; CHROMOSOMAL MAPPING; CLASSIFICATION; DNA SEQUENCE; GENETIC DATABASE; GENETIC EPIGENESIS; GENETICS; INFORMATION PROCESSING; MICROFLORA; PROCEDURES; SPECIES DIFFERENCE;

ALGORITHMS; BACTERIA; CHROMOSOME MAPPING; DATABASES, GENETIC; DATASETS AS TOPIC; EPIGENESIS, GENETIC; GENOME, BACTERIAL; METAGENOMICS; MICROBIOTA; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY;

EID: 84943595976     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3329     Document Type: Article

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