Antimicrobials inspired by nonribosomal peptide synthetase gene clusters

Journal of the American Chemical Society

Volumn 139, Issue 4, 2017, Pages 1404-1407

  Vila Farres, Xavier ^a   Chu, John ^a   Inoyama, Daigo ^b   Ternei, Melinda A ^a   Lemetre, Christophe ^a   Cohen, Louis J ^a   Cho, Wooyoung ^a   Reddy, Boojala Vijay B ^a   Zebroski, Henry A ^a   Freundlich, Joel S ^b   Perlin, David S ^c   Brady, Sean F ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENTS; BIOSYNTHESIS; PEPTIDES;

BACTERIAL CULTURES; BIOSYNTHETIC GENE CLUSTER; FUNGAL PATHOGEN; MICROBIAL PATHOGENS; NATURAL PRODUCTS; NONRIBOSOMAL PEPTIDE SYNTHETASES; PRIMARY SEQUENCES; SMALL MOLECULES;

GENES;

BACTERIAL EXTRACT; NONRIBOSOMAL PEPTIDE SYNTHETASE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; BIOLOGICAL PRODUCT; PEPTIDE SYNTHASE;

ACINETOBACTER BAUMANNII; AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GENOME; BACTERIUM CULTURE; BIOSYNTHESIS; CANDIDA ALBICANS; DNA SEQUENCE; DRUG IDENTIFICATION; DRUG SCREENING; ENTEROBACTER CLOACAE; ENTEROCOCCUS FAECIUM; GENE CLUSTER; GENE SEQUENCE; KLEBSIELLA PNEUMONIAE; MEMBRANE DEPOLARIZATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PEPTIDE SYNTHESIS; PREDICTION; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; SYNTHESIS; BACTERIUM; BIOLOGY; CHEMISTRY; DRUG EFFECT; FUNGUS; GENETICS; METABOLISM; MICROBIAL SENSITIVITY TEST; MULTIGENE FAMILY;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BACTERIA; BIOLOGICAL PRODUCTS; COMPUTATIONAL BIOLOGY; FUNGI; MICROBIAL SENSITIVITY TESTS; MULTIGENE FAMILY; PEPTIDE SYNTHASES;

EID: 85011309166     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.6b11861     Document Type: Article

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