Biosynthesis of therapeutic natural products using synthetic biology

Advanced Drug Delivery Reviews

Volumn 105, Issue , 2016, Pages 96-106

  Awan, Ali R ^a   Shaw, William M ^a   Ellis, Tom ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Alkaloids; Natural products; Nonribosomal peptides; Polyketides; Synthetic biology; Terpenoids; Therapeutics

Indexed keywords

ALKALOIDS; BIOCHEMISTRY; BIOSYNTHESIS; GENETIC ENGINEERING; METABOLIC ENGINEERING; PLANTS (BOTANY);

NATURAL PRODUCTS; NONRIBOSOMAL PEPTIDE; POLYKETIDES; SYNTHETIC BIOLOGY; TERPENOIDS; THERAPEUTICS;

DRUG PRODUCTS;

ALKALOID; ARTEMISINIC ACID; ARTEMISININ; BISBENZYLISOQUINOLINE ALKALOID; DAPTOMYCIN; FLAVONOID; INDOLE ALKALOID; LEVODOPA; MEVINOLIN; MORPHINE; NATURAL PRODUCT; PACLITAXEL; PENICILLIN DERIVATIVE; PEPTIDE; POLYKETIDE; POLYPEPTIDE ANTIBIOTIC AGENT; RHIZOXIN; SAPONIN; TERPENE; TERPENE INDOLE ALKALOID; TERPENOID; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE; BIOLOGICAL PRODUCT;

ASPERGILLUS; ASPERGILLUS ORYZAE; BIOSENSOR; DIRECTED MOLECULAR EVOLUTION; DRUG SYNTHESIS; ESCHERICHIA COLI; GENE CLUSTER; GENE EXPRESSION; GENETIC ENGINEERING; GENOME; GENOMICS; HUMAN; KOMAGATAELLA PASTORIS; LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; METABOLIC ENGINEERING; METAGENOMICS; NONHUMAN; OGATAEA ANGUSTA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ENGINEERING; PROTEOMICS; REVIEW; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; STREPTOMYCES; SYNTHETIC BIOLOGY;

BIOLOGICAL PRODUCTS; HUMANS; SYNTHETIC BIOLOGY;

EID: 84975780687     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2016.04.010     Document Type: Review

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