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1
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25444524604
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Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial 'pan-genome'
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in press.
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Tettelin H, Masignani V, Cieslewicz MJ, Donati C, Medini D, Ward NL, Angiuoli SV, Crabtree J, Jones A, Durkin AS et al.: Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial 'pan-genome'. Proc Natl Acad Sci USA 2005, in press. This study reports the first quantification of the diversity of a single prokaryotic species on the basis of genomic sequences of multiple strains. The authors introduce the pan-genome concept: the gene pool pertaining to a single species, which can be orders of magnitude larger than the genome of any single isolate.
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(2005)
Proc Natl Acad Sci USA
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Tettelin, H.1
Masignani, V.2
Cieslewicz, M.J.3
Donati, C.4
Medini, D.5
Ward, N.L.6
Angiuoli, S.V.7
Crabtree, J.8
Jones, A.9
Durkin, A.S.10
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2
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0035902534
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Evolutionary genomics of Staphylococcus aureus: Insights into the origin of methicillin-resistant strains and the toxic shock syndrome epidemic
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J.R. Fitzgerald, D.E. Sturdevant, S.M. Mackie, S.R. Gill, and J.M. Musser Evolutionary genomics of Staphylococcus aureus: insights into the origin of methicillin-resistant strains and the toxic shock syndrome epidemic Proc Natl Acad Sci USA 98 2001 8821 8826
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(2001)
Proc Natl Acad Sci USA
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Fitzgerald, J.R.1
Sturdevant, D.E.2
MacKie, S.M.3
Gill, S.R.4
Musser, J.M.5
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3
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0034756445
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Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity
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N. Dorrell, J.A. Mangan, K.G. Laing, J. Hinds, D. Linton, H. Al-Ghusein, B.G. Barrell, J. Parkhill, N.G. Stoker, and A.V. Karlyshev Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity Genome Res 11 2001 1706 1715
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(2001)
Genome Res
, vol.11
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Dorrell, N.1
Mangan, J.A.2
Laing, K.G.3
Hinds, J.4
Linton, D.5
Al-Ghusein, H.6
Barrell, B.G.7
Parkhill, J.8
Stoker, N.G.9
Karlyshev, A.V.10
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4
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2942571207
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Extensive genomic diversity in pathogenic Escherichia coli and Shigella strains revealed by comparative genomic hybridization microarray
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S. Fukiya, H. Mizoguchi, T. Tobe, and H. Mori Extensive genomic diversity in pathogenic Escherichia coli and Shigella strains revealed by comparative genomic hybridization microarray J Bacteriol 186 2004 3911 3921
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(2004)
J Bacteriol
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Fukiya, S.1
Mizoguchi, H.2
Tobe, T.3
Mori, H.4
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5
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11144354360
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Environmental genome shotgun sequencing of the Sargasso sea
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J.C. Venter, K. Remington, J.F. Heidelberg, A.L. Halpern, D. Rusch, J.A. Eisen, D. Wu, I. Paulsen, K.E. Nelson, and W. Nelson Environmental genome shotgun sequencing of the Sargasso sea Science 304 2004 66 74 The first work in which the 'whole-genome shotgun sequencing technique' was applied to an environmental sample. It greatly improves our understanding of how complex and variable is the world of uncultured bacteria.
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(2004)
Science
, vol.304
, pp. 66-74
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Venter, J.C.1
Remington, K.2
Heidelberg, J.F.3
Halpern, A.L.4
Rusch, D.5
Eisen, J.A.6
Wu, D.7
Paulsen, I.8
Nelson, K.E.9
Nelson, W.10
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6
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20544444045
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Diversity of the human intestinal microbial flora
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P.B. Eckburg, E.M. Bik, C.N. Bernstein, E. Purdom, L. Dethlefsen, M. Sargent, S.R. Gill, K.E. Nelson, and D.A. Relman Diversity of the human intestinal microbial flora Science 308 2005 1635 1638 A study showing that intestinal flora contains a much higher number of species than expected, with relevant variations both between different sites and between different subjects.
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(2005)
Science
, vol.308
, pp. 1635-1638
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Eckburg, P.B.1
Bik, E.M.2
Bernstein, C.N.3
Purdom, E.4
Dethlefsen, L.5
Sargent, M.6
Gill, S.R.7
Nelson, K.E.8
Relman, D.A.9
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7
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23944525404
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Computational improvements reveal great bacterial diversity and high metal toxicity in soil
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J. Gans, M. Wolinsky, and J. Dunbar Computational improvements reveal great bacterial diversity and high metal toxicity in soil Science 309 2005 1387 1390 This excellent study introduces innovative computational methods for measuring species abundance in environmental samples, leading to an increase of more than two orders of magnitude in current estimates of species diversity.
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(2005)
Science
, vol.309
, pp. 1387-1390
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Gans, J.1
Wolinsky, M.2
Dunbar, J.3
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8
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0032856426
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Analysis of bacterial communities in heavy metal-contaminated soils at different levels of resolution
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R. Sandaa, V. Torsvik, Ø. Enger, F.L. Daae, T. Castberg, and D. Hahn Analysis of bacterial communities in heavy metal-contaminated soils at different levels of resolution FEMS Microbiol Ecol 30 1999 237 251
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(1999)
FEMS Microbiol Ecol
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Sandaa, R.1
Torsvik, V.2
Enger Ø3
Daae, F.L.4
Castberg, T.5
Hahn, D.6
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9
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85071411305
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Exploring microbial diversity - A vast below
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T.P. Curtis, and W.T. Sloan Exploring microbial diversity - a vast below Science 309 2005 1332 1333 Illuminating perspective on the new frontiers opened in microbial ecology by the use of advanced mathematical and computational approaches to the quantification of prokaryotic diversity.
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(2005)
Science
, vol.309
, pp. 1332-1333
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Curtis, T.P.1
Sloan, W.T.2
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10
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14544287770
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Genotypic diversity within a natural coastal bacterioplankton population
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J.R. Thompson, S. Pacocha, C. Pharino, V. Klepac-Ceraj, D.E. Hunt, J. Benoit, R. Sarma-Rupavtarm, D.L. Distel, and M.F. Polz Genotypic diversity within a natural coastal bacterioplankton population Science 307 2005 1311 1313 This study presents illuminating data on the genetic diversity of a bacterial population, clearly showing that macroscopic differences in genetic content are present also within seemingly homogeneous populations from a single ecosystem.
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(2005)
Science
, vol.307
, pp. 1311-1313
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Thompson, J.R.1
Pacocha, S.2
Pharino, C.3
Klepac-Ceraj, V.4
Hunt, D.E.5
Benoit, J.6
Sarma-Rupavtarm, R.7
Distel, D.L.8
Polz, M.F.9
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12
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0242490943
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Lateral gene transfer: When will adolescence end?
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J.G. Lawrence, and H. Hendrickson Lateral gene transfer: when will adolescence end? Mol Microbiol 50 2003 739 749
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(2003)
Mol Microbiol
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Lawrence, J.G.1
Hendrickson, H.2
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0242606207
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Horizontal gene transfer: The path to maturity
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E.V. Koonin Horizontal gene transfer: the path to maturity Mol Microbiol 50 2003 725 727
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(2003)
Mol Microbiol
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Koonin, E.V.1
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14
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18244380086
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Examining bacterial species under the specter of gene transfer and exchange
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H. Ochman, E. Lerat, and V. Daubin Examining bacterial species under the specter of gene transfer and exchange Proc Natl Acad Sci USA 102 Suppl 1 2005 6595 6599
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(2005)
Proc Natl Acad Sci USA
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Ochman, H.1
Lerat, E.2
Daubin, V.3
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15
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18244402898
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Decoding the genomic tree of life
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A.B. Simonson, J.A. Servin, R.G. Skophammer, C.W. Herbold, M.C. Rivera, and J.A. Lake Decoding the genomic tree of life Proc Natl Acad Sci USA 102 Suppl 1 2005 6608 6613
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Proc Natl Acad Sci USA
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Simonson, A.B.1
Servin, J.A.2
Skophammer, R.G.3
Herbold, C.W.4
Rivera, M.C.5
Lake, J.A.6
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16
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0642344263
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Duplication is more common among laterally transferred genes than among indigenous genes
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S.D. Hooper, and O.G. Berg Duplication is more common among laterally transferred genes than among indigenous genes Genome Biol 4 2003 R48
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(2003)
Genome Biol
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Hooper, S.D.1
Berg, O.G.2
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2442449227
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Genomic islands in pathogenic and environmental microorganisms
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U. Dobrindt, B. Hochhut, U. Hentschel, and J. Hacker Genomic islands in pathogenic and environmental microorganisms Nat Rev Microbiol 2 2004 414 424 Comprehensive review presenting the results on lateral gene transfer obtained for pathogenicity islands in pathogenic bacteria. It shows that lateral gene transfer is a universal mechanism of evolution.
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(2004)
Nat Rev Microbiol
, vol.2
, pp. 414-424
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Dobrindt, U.1
Hochhut, B.2
Hentschel, U.3
Hacker, J.4
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1542513556
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Mobile elements: Drivers of genome evolution
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H.H. Kazazian Jr. Mobile elements: drivers of genome evolution Science 303 2004 1626 1632
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(2004)
Science
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Kazazian Jr., H.H.1
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4544321685
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Phages and the evolution of bacterial pathogens: From genomic rearrangements to lysogenic conversion
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H. Brussow, C. Canchaya, and W.D. Hardt Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion Microbiol Mol Biol Rev 68 2004 560 602 A clear review highlighting the importance of phages as a source of novel genes in bacterial evolution.
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(2004)
Microbiol Mol Biol Rev
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Brussow, H.1
Canchaya, C.2
Hardt, W.D.3
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20
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0242323595
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Bacteriophage genomics
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R.W. Hendrix Bacteriophage genomics Curr Opin Microbiol 6 2003 506 511
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(2003)
Curr Opin Microbiol
, vol.6
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Hendrix, R.W.1
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3042569657
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Bacterial genomes as new gene homes: The genealogy of ORFans in E. coli
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V. Daubin, and H. Ochman Bacterial genomes as new gene homes: the genealogy of ORFans in E. coli Genome Res 14 2004 1036 1042
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(2004)
Genome Res
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Daubin, V.1
Ochman, H.2
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2942679276
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Small change: Keeping pace with microevolution
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E.J. Feil Small change: keeping pace with microevolution Nat Rev Microbiol 2 2004 483 495 Outstanding review, detailing the latest experimental results for characterizing species variability, with a special focus on genome sequencing, microarray and MLST data. The consequences on the concept of species and on evolutionary mechanisms in bacteria are thoroughly discussed.
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(2004)
Nat Rev Microbiol
, vol.2
, pp. 483-495
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Feil, E.J.1
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23
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21644488274
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Genome analysis reveals pili in Group B Streptococcus
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P. Lauer, C.D. Rinaudo, M. Soriani, I. Margarit, D. Maione, R. Rosini, A.R. Taddei, M. Mora, R. Rappuoli, and G. Grandi Genome analysis reveals pili in Group B Streptococcus Science 309 2005 105
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(2005)
Science
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, pp. 105
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Lauer, P.1
Rinaudo, C.D.2
Soriani, M.3
Margarit, I.4
Maione, D.5
Rosini, R.6
Taddei, A.R.7
Mora, M.8
Rappuoli, R.9
Grandi, G.10
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24
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0037189373
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50 million years of genomic stasis in endosymbiotic bacteria
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I. Tamas, L. Klasson, B. Canback, A.K. Naslund, A.S. Eriksson, J.J. Wernegreen, J.P. Sandstrom, N.A. Moran, and S.G. Andersson 50 million years of genomic stasis in endosymbiotic bacteria Science 296 2002 2376 2379
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Science
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Tamas, I.1
Klasson, L.2
Canback, B.3
Naslund, A.K.4
Eriksson, A.S.5
Wernegreen, J.J.6
Sandstrom, J.P.7
Moran, N.A.8
Andersson, S.G.9
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26
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21644481459
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Identification of a universal group B Streptococcus vaccine by multiple genome screen
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D. Maione, I. Margarit, C.D. Rinaudo, V. Masignani, M. Mora, M. Scarselli, H. Tettelin, C. Brettoni, E.T. Iacobini, and R. Rosini Identification of a universal group B Streptococcus vaccine by multiple genome screen Science 309 2005 148 150 A clear demonstration of the practical importance of sequencing multiple strains of a single pathogen for the formulation of an effective vaccine.
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(2005)
Science
, vol.309
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Maione, D.1
Margarit, I.2
Rinaudo, C.D.3
Masignani, V.4
Mora, M.5
Scarselli, M.6
Tettelin, H.7
Brettoni, C.8
Iacobini, E.T.9
Rosini, R.10
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