Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution

BMC Evolutionary Biology

Volumn 7, Issue , 2007, Pages

  Rausch, Christian ^a   Hoof, Ilka ^a,b   Weber, Tilmann ^a   Wohlleben, Wolfgang ^a   Huson, Daniel H ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMANITIN; AMINO ACID DERIVATIVE; BETA HYDROXYCARBOXYLIC ACID; BETA HYDROXYL FATTY ACID; BLEOMYCIN; CYCLOSPORIN A; CYSTEINE; NON RIBOSOMAL PEPTIDE SYNTHASE; PENICILLIN G; PEPTIDE SYNTHASE; SERINE; THREONINE; UNCLASSIFIED DRUG; VANCOMYCIN; NON-RIBOSOMAL PEPTIDE SYNTHASE;

ARTICLE; CATALYSIS; CYCLIZATION; ENZYME STRUCTURE; ENZYME SYNTHESIS; EPIMERIZATION; HIDDEN MARKOV MODEL; MOLECULAR EVOLUTION; NONHUMAN; NONRIBOSOMAL PEPTIDE SYNTHESIS; PEPTIDE ANALYSIS; PHYLOGENY; POLYMERIZATION; PROTEIN DOMAIN; PROTEIN MOTIF; STATISTICAL MODEL; AMINO ACID SEQUENCE; BACTERIAL GENOME; BACTERIUM; CLASSIFICATION; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BACTERIA; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENOME, BACTERIAL; PEPTIDE SYNTHASES; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 34250710858     PISSN: None     EISSN: 14712148     Source Type: Journal    
DOI: 10.1186/1471-2148-7-78     Document Type: Article

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