-
1
-
-
77957921865
-
Potential for chlorine gas-induced injury in the extrapulmonary vasculature
-
Samal, A., Honovar, J., White, C.R., Patel, R.P., Potential for chlorine gas-induced injury in the extrapulmonary vasculature. Proc. Am. Thorac. Soc. 7 (2010), 290–293.
-
(2010)
Proc. Am. Thorac. Soc.
, vol.7
, pp. 290-293
-
-
Samal, A.1
Honovar, J.2
White, C.R.3
Patel, R.P.4
-
2
-
-
77953491262
-
Environmental hazards of sea-dumped chemical weapons
-
Sanderson, H., Fauser, P., Thomsen, M., Vanninen, P., Soderstrom, M., Savin, Y., Khalikov, I., Hirvonen, A., Niiranen, S., Missiaen, T., Gress, A., Borodin, P., Medvedeva, N., Polyak, Y., Paka, V., Zhurbas, V., Feller, P., Environmental hazards of sea-dumped chemical weapons. Environ. Sci. Technol. 44 (2010), 4389–4394.
-
(2010)
Environ. Sci. Technol.
, vol.44
, pp. 4389-4394
-
-
Sanderson, H.1
Fauser, P.2
Thomsen, M.3
Vanninen, P.4
Soderstrom, M.5
Savin, Y.6
Khalikov, I.7
Hirvonen, A.8
Niiranen, S.9
Missiaen, T.10
Gress, A.11
Borodin, P.12
Medvedeva, N.13
Polyak, Y.14
Paka, V.15
Zhurbas, V.16
Feller, P.17
-
4
-
-
77956916981
-
Management of phosgene-induced acute lung injury
-
Grainge, C., Rice, P., Management of phosgene-induced acute lung injury. Clin. Toxicol. (Phila) 48 (2010), 497–508.
-
(2010)
Clin. Toxicol. (Phila)
, vol.48
, pp. 497-508
-
-
Grainge, C.1
Rice, P.2
-
5
-
-
79251593999
-
Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity
-
Weinberger, B., Laskin, J.D., Sunil, V.R., Sinko, P.J., Heck, D.E., Laskin, D.L., Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity. Pulmonary Pharmacol. Ther. 24 (2011), 92–99.
-
(2011)
Pulmonary Pharmacol. Ther.
, vol.24
, pp. 92-99
-
-
Weinberger, B.1
Laskin, J.D.2
Sunil, V.R.3
Sinko, P.J.4
Heck, D.E.5
Laskin, D.L.6
-
6
-
-
84930091540
-
Implementing Toxicity Testing in the 21 st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment
-
Adeleye, Y., Andersen, M., Clewell, R., Davies, M., Dent, M., Edwards, S., Fowler, P., Malcomber, S., Nicol, B., Scott, A., Scott, S., Sun, B., Westmoreland, C., White, A., Zhang, Q., Carmichael, P.L., Implementing Toxicity Testing in the 21 st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment. Toxicology 332 (2015), 102–111.
-
(2015)
Toxicology
, vol.332
, pp. 102-111
-
-
Adeleye, Y.1
Andersen, M.2
Clewell, R.3
Davies, M.4
Dent, M.5
Edwards, S.6
Fowler, P.7
Malcomber, S.8
Nicol, B.9
Scott, A.10
Scott, S.11
Sun, B.12
Westmoreland, C.13
White, A.14
Zhang, Q.15
Carmichael, P.L.16
-
7
-
-
84894339604
-
Chemosensory TRP channels in the respiratory tract: role in toxic lung injury and potential as sweet spots for targeted therapies
-
Buch, T., Schafer, E., Steinritz, D., Dietrich, A., Gudermann, T., Chemosensory TRP channels in the respiratory tract: role in toxic lung injury and potential as sweet spots for targeted therapies. Rev. Physiol. Biochem. Pharmacol. 165 (2013), 31–65.
-
(2013)
Rev. Physiol. Biochem. Pharmacol.
, vol.165
, pp. 31-65
-
-
Buch, T.1
Schafer, E.2
Steinritz, D.3
Dietrich, A.4
Gudermann, T.5
-
8
-
-
0022347577
-
Rescue of the Drosophila phototransduction mutation trp by germline transformation
-
Montell, C., Jones, K., Hafen, E., Rubin, G., Rescue of the Drosophila phototransduction mutation trp by germline transformation. Science, 1985, 1040–1043.
-
(1985)
Science
, pp. 1040-1043
-
-
Montell, C.1
Jones, K.2
Hafen, E.3
Rubin, G.4
-
9
-
-
0024642547
-
Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction
-
Montell, C., Rubin, G.M., Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction. Neuron 2 (1989), 1313–1323.
-
(1989)
Neuron
, vol.2
, pp. 1313-1323
-
-
Montell, C.1
Rubin, G.M.2
-
10
-
-
0026583241
-
The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors
-
Hardie, R.C., Minke, B., The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors. Neuron 8 (1992), 643–651.
-
(1992)
Neuron
, vol.8
, pp. 643-651
-
-
Hardie, R.C.1
Minke, B.2
-
11
-
-
85056746661
-
Classical transient receptor potential 1 (TRPC1): channel or channel regulator?
-
Dietrich, A., Fahlbusch, M., Gudermann, T., Classical transient receptor potential 1 (TRPC1): channel or channel regulator?. Cells 3 (2014), 939–962.
-
(2014)
Cells
, vol.3
, pp. 939-962
-
-
Dietrich, A.1
Fahlbusch, M.2
Gudermann, T.3
-
12
-
-
21344474626
-
Functional characterization and physiological relevance of the TRPC3/6/7 subfamily of cation channels
-
Dietrich, A., Mederos y Schnitzler, M., Kalwa, H., Storch, U., Gudermann, T., Functional characterization and physiological relevance of the TRPC3/6/7 subfamily of cation channels. Naunyn Schmiedebergs Arch. Pharmacol. 371 (2005), 257–265.
-
(2005)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.371
, pp. 257-265
-
-
Dietrich, A.1
Mederos y Schnitzler, M.2
Kalwa, H.3
Storch, U.4
Gudermann, T.5
-
13
-
-
85008147871
-
Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol
-
Storch, U., Forst, A.L., Pardatscher, F., Erdogmus, S., Philipp, M., Gregoritza, M., Mederos, Y.S.M., Gudermann, T., Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol. Proc. Natl. Acad. Sci. U. S. A. 114 (2017), E37–E46.
-
(2017)
Proc. Natl. Acad. Sci. U. S. A.
, vol.114
, pp. E37-E46
-
-
Storch, U.1
Forst, A.L.2
Pardatscher, F.3
Erdogmus, S.4
Philipp, M.5
Gregoritza, M.6
Mederos, Y.S.M.7
Gudermann, T.8
-
14
-
-
0033590450
-
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol
-
Hofmann, T., Obukhov, A.G., Schaefer, M., Harteneck, C., Gudermann, T., Schultz, G., Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature 397 (1999), 259–263.
-
(1999)
Nature
, vol.397
, pp. 259-263
-
-
Hofmann, T.1
Obukhov, A.G.2
Schaefer, M.3
Harteneck, C.4
Gudermann, T.5
Schultz, G.6
-
15
-
-
0030725660
-
Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein
-
Boulay, G., Zhu, X., Peyton, M., Jiang, M., Hurst, R., Stefani, E., Birnbaumer, L., Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein. J. Biol. Chem. 272 (1997), 29672–29680.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29672-29680
-
-
Boulay, G.1
Zhu, X.2
Peyton, M.3
Jiang, M.4
Hurst, R.5
Stefani, E.6
Birnbaumer, L.7
-
16
-
-
84904868444
-
TRPC6: physiological function and pathophysiological relevance
-
Dietrich, A., Gudermann, T., TRPC6: physiological function and pathophysiological relevance. Handb. Exp. Pharmacol. 222 (2014), 157–188.
-
(2014)
Handb. Exp. Pharmacol.
, vol.222
, pp. 157-188
-
-
Dietrich, A.1
Gudermann, T.2
-
17
-
-
2442542398
-
Regulation of TRPC6 channel activity by tyrosine phosphorylation
-
Hisatsune, C., Kuroda, Y., Nakamura, K., Inoue, T., Nakamura, T., Michikawa, T., Mizutani, A., Mikoshiba, K., Regulation of TRPC6 channel activity by tyrosine phosphorylation. J. Biol. Chem. 279 (2004), 18887–18894.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18887-18894
-
-
Hisatsune, C.1
Kuroda, Y.2
Nakamura, K.3
Inoue, T.4
Nakamura, T.5
Michikawa, T.6
Mizutani, A.7
Mikoshiba, K.8
-
18
-
-
51749086155
-
Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6
-
Takahashi, S., Lin, H., Geshi, N., Mori, Y., Kawarabayashi, Y., Takami, N., Mori, M.X., Honda, A., Inoue, R., Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. J. Physiol. 586 (2008), 4209–4223.
-
(2008)
J. Physiol.
, vol.586
, pp. 4209-4223
-
-
Takahashi, S.1
Lin, H.2
Geshi, N.3
Mori, Y.4
Kawarabayashi, Y.5
Takami, N.6
Mori, M.X.7
Honda, A.8
Inoue, R.9
-
19
-
-
77949274491
-
Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition
-
Koitabashi, N., Aiba, T., Hesketh, G.G., Rowell, J., Zhang, M., Takimoto, E., Tomaselli, G.F., Kass, D.A., Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition. J. Mol. Cell. Cardiol. 48 (2010), 713–724.
-
(2010)
J. Mol. Cell. Cardiol.
, vol.48
, pp. 713-724
-
-
Koitabashi, N.1
Aiba, T.2
Hesketh, G.G.3
Rowell, J.4
Zhang, M.5
Takimoto, E.6
Tomaselli, G.F.7
Kass, D.A.8
-
20
-
-
77951232473
-
Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition
-
Nishida, M., Watanabe, K., Sato, Y., Nakaya, M., Kitajima, N., Ide, T., Inoue, R., Kurose, H., Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition. J. Biol. Chem. 285 (2010), 13244–13253.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 13244-13253
-
-
Nishida, M.1
Watanabe, K.2
Sato, Y.3
Nakaya, M.4
Kitajima, N.5
Ide, T.6
Inoue, R.7
Kurose, H.8
-
21
-
-
77954214838
-
Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart
-
Kinoshita, H., Kuwahara, K., Nishida, M., Jian, Z., Rong, X., Kiyonaka, S., Kuwabara, Y., Kurose, H., Inoue, R., Mori, Y., Li, Y., Nakagawa, Y., Usami, S., Fujiwara, M., Yamada, Y., Minami, T., Ueshima, K., Nakao, K., Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart. Circ. Res. 106 (2010), 1849–1860.
-
(2010)
Circ. Res.
, vol.106
, pp. 1849-1860
-
-
Kinoshita, H.1
Kuwahara, K.2
Nishida, M.3
Jian, Z.4
Rong, X.5
Kiyonaka, S.6
Kuwabara, Y.7
Kurose, H.8
Inoue, R.9
Mori, Y.10
Li, Y.11
Nakagawa, Y.12
Usami, S.13
Fujiwara, M.14
Yamada, Y.15
Minami, T.16
Ueshima, K.17
Nakao, K.18
-
22
-
-
38649130401
-
Long-term treatment with sildenafil in chronic thromboembolic pulmonary hypertension
-
Reichenberger, F., Voswinckel, R., Enke, B., Rutsch, M., El Fechtali, E., Schmehl, T., Olschewski, H., Schermuly, R., Weissmann, N., Ghofrani, H.A., Grimminger, F., Mayer, E., Seeger, W., Long-term treatment with sildenafil in chronic thromboembolic pulmonary hypertension. Eur. Resp. J. 30 (2007), 922–927.
-
(2007)
Eur. Resp. J.
, vol.30
, pp. 922-927
-
-
Reichenberger, F.1
Voswinckel, R.2
Enke, B.3
Rutsch, M.4
El Fechtali, E.5
Schmehl, T.6
Olschewski, H.7
Schermuly, R.8
Weissmann, N.9
Ghofrani, H.A.10
Grimminger, F.11
Mayer, E.12
Seeger, W.13
-
23
-
-
84904913362
-
TRPC4- and TRPC4-containing channels
-
Freichel, M., Tsvilovskyy, V., Camacho-Londono, J.E., TRPC4- and TRPC4-containing channels. Handb. Exp. Pharmacol. 222 (2014), 85–128.
-
(2014)
Handb. Exp. Pharmacol.
, vol.222
, pp. 85-128
-
-
Freichel, M.1
Tsvilovskyy, V.2
Camacho-Londono, J.E.3
-
24
-
-
0034625452
-
Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5
-
Schaefer, M., Plant, T.D., Obukhov, A.G., Hofmann, T., Gudermann, T., Schultz, G., Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5. J. Biol. Chem. 275 (2000), 17517–17526.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17517-17526
-
-
Schaefer, M.1
Plant, T.D.2
Obukhov, A.G.3
Hofmann, T.4
Gudermann, T.5
Schultz, G.6
-
25
-
-
0037423392
-
Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth
-
Jung, S., Muhle, A., Schaefer, M., Strotmann, R., Schultz, G., Plant, T.D., Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth. J. Biol. Chem. 278 (2003), 3562–3571.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 3562-3571
-
-
Jung, S.1
Muhle, A.2
Schaefer, M.3
Strotmann, R.4
Schultz, G.5
Plant, T.D.6
-
26
-
-
33750257552
-
Nitric oxide activates TRP channels by cysteine S-nitrosylation
-
Yoshida, T., Inoue, R., Morii, T., Takahashi, N., Yamamoto, S., Hara, Y., Tominaga, M., Shimizu, S., Sato, Y., Mori, Y., Nitric oxide activates TRP channels by cysteine S-nitrosylation. Nat. Chem. Biol. 2 (2006), 596–607.
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 596-607
-
-
Yoshida, T.1
Inoue, R.2
Morii, T.3
Takahashi, N.4
Yamamoto, S.5
Hara, Y.6
Tominaga, M.7
Shimizu, S.8
Sato, Y.9
Mori, Y.10
-
27
-
-
60249099419
-
Zinc activates damage-sensing TRPA1 ion channels
-
Hu, H., Bandell, M., Petrus, M.J., Zhu, M.X., Patapoutian, A., Zinc activates damage-sensing TRPA1 ion channels. Nat. Chem. Biol. 5 (2009), 183–190.
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 183-190
-
-
Hu, H.1
Bandell, M.2
Petrus, M.J.3
Zhu, M.X.4
Patapoutian, A.5
-
29
-
-
33847241778
-
Direct activation of the ion channel TRPA1 by Ca2+
-
Zurborg, S., Yurgionas, B., Jira, J.A., Caspani, O., Heppenstall, P.A., Direct activation of the ion channel TRPA1 by Ca2+. Nat. Neurosci. 10 (2007), 277–279.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 277-279
-
-
Zurborg, S.1
Yurgionas, B.2
Jira, J.A.3
Caspani, O.4
Heppenstall, P.A.5
-
30
-
-
52949088257
-
Contribution of TRPV1 to the bradykinin-evoked nociceptive behavior and excitation of cutaneous sensory neurons
-
Katanosaka, K., Banik, R.K., Giron, R., Higashi, T., Tominaga, M., Mizumura, K., Contribution of TRPV1 to the bradykinin-evoked nociceptive behavior and excitation of cutaneous sensory neurons. Neurosci. Res. 62 (2008), 168–175.
-
(2008)
Neurosci. Res.
, vol.62
, pp. 168-175
-
-
Katanosaka, K.1
Banik, R.K.2
Giron, R.3
Higashi, T.4
Tominaga, M.5
Mizumura, K.6
-
31
-
-
80052960971
-
TRPA1 underlies a sensing mechanism for O2
-
Takahashi, N., Kuwaki, T., Kiyonaka, S., Numata, T., Kozai, D., Mizuno, Y., Yamamoto, S., Naito, S., Knevels, E., Carmeliet, P., Oga, T., Kaneko, S., Suga, S., Nokami, T., Yoshida, J., Mori, Y., TRPA1 underlies a sensing mechanism for O2. Nat. Chem. Biol. 7 (2011), 701–711.
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 701-711
-
-
Takahashi, N.1
Kuwaki, T.2
Kiyonaka, S.3
Numata, T.4
Kozai, D.5
Mizuno, Y.6
Yamamoto, S.7
Naito, S.8
Knevels, E.9
Carmeliet, P.10
Oga, T.11
Kaneko, S.12
Suga, S.13
Nokami, T.14
Yoshida, J.15
Mori, Y.16
-
32
-
-
84957812540
-
Quaternary lidocaine derivative QX-314 activates and permeates human TRPV1 and TRPA1 to produce inhibition of sodium channels and cytotoxicity
-
Stueber, T., Eberhardt, M.J., Hadamitzky, C., Jangra, A., Schenk, S., Dick, F., Stoetzer, C., Kistner, K., Reeh, P.W., Binshtok, A.M., Leffler, A., Quaternary lidocaine derivative QX-314 activates and permeates human TRPV1 and TRPA1 to produce inhibition of sodium channels and cytotoxicity. Anesthesiology 124 (2016), 1153–1165.
-
(2016)
Anesthesiology
, vol.124
, pp. 1153-1165
-
-
Stueber, T.1
Eberhardt, M.J.2
Hadamitzky, C.3
Jangra, A.4
Schenk, S.5
Dick, F.6
Stoetzer, C.7
Kistner, K.8
Reeh, P.W.9
Binshtok, A.M.10
Leffler, A.11
-
33
-
-
77952650740
-
Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation
-
Banke, T.G., Chaplan, S.R., Wickenden, A.D., Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation. Am. J. Physiol. Cell Physiol. 298 (2010), C1457–1468.
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.298
, pp. C1457-1468
-
-
Banke, T.G.1
Chaplan, S.R.2
Wickenden, A.D.3
-
34
-
-
59849114038
-
Pore dilation occurs in TRPA1 but not in TRPM8 channels
-
Chen, J., Kim, D., Bianchi, B.R., Cavanaugh, E.J., Faltynek, C.R., Kym, P.R., Reilly, R.M., Pore dilation occurs in TRPA1 but not in TRPM8 channels. Mol. Pain, 5, 2009, 3.
-
(2009)
Mol. Pain
, vol.5
, pp. 3
-
-
Chen, J.1
Kim, D.2
Bianchi, B.R.3
Cavanaugh, E.J.4
Faltynek, C.R.5
Kym, P.R.6
Reilly, R.M.7
-
35
-
-
84966473894
-
Photosensitization in porphyrias and photodynamic therapy involves TRPA1 and TRPV1
-
Babes, A., Sauer, S.K., Moparthi, L., Kichko, T.I., Neacsu, C., Namer, B., Filipovic, M., Zygmunt, P.M., Reeh, P.W., Fischer, M.J., Photosensitization in porphyrias and photodynamic therapy involves TRPA1 and TRPV1. J. Neurosci. 36 (2016), 5264–5278.
-
(2016)
J. Neurosci.
, vol.36
, pp. 5264-5278
-
-
Babes, A.1
Sauer, S.K.2
Moparthi, L.3
Kichko, T.I.4
Neacsu, C.5
Namer, B.6
Filipovic, M.7
Zygmunt, P.M.8
Reeh, P.W.9
Fischer, M.J.10
-
36
-
-
0033548702
-
An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts
-
Jaquemar, D., Schenker, T., Trueb, B., An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts. J. Biol. Chem. 274 (1999), 7325–7333.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7325-7333
-
-
Jaquemar, D.1
Schenker, T.2
Trueb, B.3
-
37
-
-
0345616438
-
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
-
Story, G.M., Peier, A.M., Reeve, A.J., Eid, S.R., Mosbacher, J., Hricik, T.R., Earley, T.J., Hergarden, A.C., Andersson, D.A., Hwang, S.W., McIntyre, P., Jegla, T., Bevan, S., Patapoutian, A., ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112 (2003), 819–829.
-
(2003)
Cell
, vol.112
, pp. 819-829
-
-
Story, G.M.1
Peier, A.M.2
Reeve, A.J.3
Eid, S.R.4
Mosbacher, J.5
Hricik, T.R.6
Earley, T.J.7
Hergarden, A.C.8
Andersson, D.A.9
Hwang, S.W.10
McIntyre, P.11
Jegla, T.12
Bevan, S.13
Patapoutian, A.14
-
38
-
-
1642430679
-
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
-
Jordt, S.E., Bautista, D.M., Chuang, H.H., McKemy, D.D., Zygmunt, P.M., Hogestatt, E.D., Meng, I.D., Julius, D., Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427 (2004), 260–265.
-
(2004)
Nature
, vol.427
, pp. 260-265
-
-
Jordt, S.E.1
Bautista, D.M.2
Chuang, H.H.3
McKemy, D.D.4
Zygmunt, P.M.5
Hogestatt, E.D.6
Meng, I.D.7
Julius, D.8
-
39
-
-
84890118536
-
Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells
-
Buch, T.R., Schafer, E.A., Demmel, M.T., Boekhoff, I., Thiermann, H., Gudermann, T., Steinritz, D., Schmidt, A., Functional expression of the transient receptor potential channel TRPA1, a sensor for toxic lung inhalants, in pulmonary epithelial cells. Chem. Biol. Interact. 206 (2013), 462–471.
-
(2013)
Chem. Biol. Interact.
, vol.206
, pp. 462-471
-
-
Buch, T.R.1
Schafer, E.A.2
Demmel, M.T.3
Boekhoff, I.4
Thiermann, H.5
Gudermann, T.6
Steinritz, D.7
Schmidt, A.8
-
40
-
-
80053044013
-
Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells
-
Mukhopadhyay, I., Gomes, P., Aranake, S., Shetty, M., Karnik, P., Damle, M., Kuruganti, S., Thorat, S., Khairatkar-Joshi, N., Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells. J. Recept. Signal Transduct. Res. 31 (2011), 350–358.
-
(2011)
J. Recept. Signal Transduct. Res.
, vol.31
, pp. 350-358
-
-
Mukhopadhyay, I.1
Gomes, P.2
Aranake, S.3
Shetty, M.4
Karnik, P.5
Damle, M.6
Kuruganti, S.7
Thorat, S.8
Khairatkar-Joshi, N.9
-
41
-
-
84865052691
-
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation
-
Nassini, R., Pedretti, P., Moretto, N., Fusi, C., Carnini, C., Facchinetti, F., Viscomi, A.R., Pisano, A.R., Stokesberry, S., Brunmark, C., Svitacheva, N., McGarvey, L., Patacchini, R., Damholt, A.B., Geppetti, P., Materazzi, S., Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation. PLoS One, 7, 2012, e42454.
-
(2012)
PLoS One
, vol.7
, pp. e42454
-
-
Nassini, R.1
Pedretti, P.2
Moretto, N.3
Fusi, C.4
Carnini, C.5
Facchinetti, F.6
Viscomi, A.R.7
Pisano, A.R.8
Stokesberry, S.9
Brunmark, C.10
Svitacheva, N.11
McGarvey, L.12
Patacchini, R.13
Damholt, A.B.14
Geppetti, P.15
Materazzi, S.16
-
42
-
-
0032533315
-
Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain
-
Nagamine, K., Kudoh, J., Minoshima, S., Kawasaki, K., Asakawa, S., Ito, F., Shimizu, N., Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain. Genomics 54 (1998), 124–131.
-
(1998)
Genomics
, vol.54
, pp. 124-131
-
-
Nagamine, K.1
Kudoh, J.2
Minoshima, S.3
Kawasaki, K.4
Asakawa, S.5
Ito, F.6
Shimizu, N.7
-
43
-
-
0034177642
-
From worm to man: three subfamilies of TRP channels
-
Harteneck, C., Plant, T.D., Schultz, G., From worm to man: three subfamilies of TRP channels. Trends Neurosci. 23 (2000), 159–166.
-
(2000)
Trends Neurosci.
, vol.23
, pp. 159-166
-
-
Harteneck, C.1
Plant, T.D.2
Schultz, G.3
-
44
-
-
18244402941
-
A unified nomenclature for the superfamily of TRP cation channels
-
Montell, C., Birnbaumer, L., Flockerzi, V., Bindels, R.J., Bruford, E.A., Caterina, M.J., Clapham, D.E., Harteneck, C., Heller, S., Julius, D., Kojima, I., Mori, Y., Penner, R., Prawitt, D., Scharenberg, A.M., Schultz, G., Shimizu, N., Zhu, M.X., A unified nomenclature for the superfamily of TRP cation channels. Mol. Cell 9 (2002), 229–231.
-
(2002)
Mol. Cell
, vol.9
, pp. 229-231
-
-
Montell, C.1
Birnbaumer, L.2
Flockerzi, V.3
Bindels, R.J.4
Bruford, E.A.5
Caterina, M.J.6
Clapham, D.E.7
Harteneck, C.8
Heller, S.9
Julius, D.10
Kojima, I.11
Mori, Y.12
Penner, R.13
Prawitt, D.14
Scharenberg, A.M.15
Schultz, G.16
Shimizu, N.17
Zhu, M.X.18
-
46
-
-
33646950509
-
Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin
-
Tong, Q., Zhang, W., Conrad, K., Mostoller, K., Cheung, J.Y., Peterson, B.Z., Miller, B.A., Regulation of the transient receptor potential channel TRPM2 by the Ca2+ sensor calmodulin. J. Biol. Chem. 281 (2006), 9076–9085.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 9076-9085
-
-
Tong, Q.1
Zhang, W.2
Conrad, K.3
Mostoller, K.4
Cheung, J.Y.5
Peterson, B.Z.6
Miller, B.A.7
-
47
-
-
0035978751
-
ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
-
Perraud, A.L., Fleig, A., Dunn, C.A., Bagley, L.A., Launay, P., Schmitz, C., Stokes, A.J., Zhu, Q., Bessman, M.J., Penner, R., Kinet, J.P., Scharenberg, A.M., ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology. Nature 411 (2001), 595–599.
-
(2001)
Nature
, vol.411
, pp. 595-599
-
-
Perraud, A.L.1
Fleig, A.2
Dunn, C.A.3
Bagley, L.A.4
Launay, P.5
Schmitz, C.6
Stokes, A.J.7
Zhu, Q.8
Bessman, M.J.9
Penner, R.10
Kinet, J.P.11
Scharenberg, A.M.12
-
48
-
-
0037636203
-
TRPM2 Ca2+ permeable cation channels: from gene to biological function
-
Perraud, A.L., Schmitz, C., Scharenberg, A.M., TRPM2 Ca2+ permeable cation channels: from gene to biological function. Cell Calcium 33 (2003), 519–531.
-
(2003)
Cell Calcium
, vol.33
, pp. 519-531
-
-
Perraud, A.L.1
Schmitz, C.2
Scharenberg, A.M.3
-
49
-
-
8744315003
-
Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2
-
Kuhn, F.J., Luckhoff, A., Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2. J. Biol. Chem. 279 (2004), 46431–46437.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 46431-46437
-
-
Kuhn, F.J.1
Luckhoff, A.2
-
50
-
-
0037449761
-
NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase
-
Perraud, A.L., Shen, B., Dunn, C.A., Rippe, K., Smith, M.K., Bessman, M.J., Stoddard, B.L., Scharenberg, A.M., NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase. J. Biol. Chem. 278 (2003), 1794–1801.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1794-1801
-
-
Perraud, A.L.1
Shen, B.2
Dunn, C.A.3
Rippe, K.4
Smith, M.K.5
Bessman, M.J.6
Stoddard, B.L.7
Scharenberg, A.M.8
-
51
-
-
20044388114
-
Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels
-
Perraud, A.L., Takanishi, C.L., Shen, B., Kang, S., Smith, M.K., Schmitz, C., Knowles, H.M., Ferraris, D., Li, W., Zhang, J., Stoddard, B.L., Scharenberg, A.M., Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels. J. Biol. Chem. 280 (2005), 6138–6148.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 6138-6148
-
-
Perraud, A.L.1
Takanishi, C.L.2
Shen, B.3
Kang, S.4
Smith, M.K.5
Schmitz, C.6
Knowles, H.M.7
Ferraris, D.8
Li, W.9
Zhang, J.10
Stoddard, B.L.11
Scharenberg, A.M.12
-
52
-
-
15944417442
-
Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels
-
Kolisek, M., Beck, A., Fleig, A., Penner, R., Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels. Mol. Cell 18 (2005), 61–69.
-
(2005)
Mol. Cell
, vol.18
, pp. 61-69
-
-
Kolisek, M.1
Beck, A.2
Fleig, A.3
Penner, R.4
-
53
-
-
0037189484
-
Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose
-
Wehage, E., Eisfeld, J., Heiner, I., Jungling, E., Zitt, C., Luckhoff, A., Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose. J. Biol. Chem. 277 (2002), 23150–23156.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23150-23156
-
-
Wehage, E.1
Eisfeld, J.2
Heiner, I.3
Jungling, E.4
Zitt, C.5
Luckhoff, A.6
-
54
-
-
4344611521
-
The mitochondrial ADPR link between Ca2+ store release and Ca2+ influx channel opening in immune cells
-
Ayub, K., Hallett, M.B., The mitochondrial ADPR link between Ca2+ store release and Ca2+ influx channel opening in immune cells. FASEB J. 18 (2004), 1335–1338.
-
(2004)
FASEB J.
, vol.18
, pp. 1335-1338
-
-
Ayub, K.1
Hallett, M.B.2
-
55
-
-
84886723521
-
Virag, poly(ADP-ribose): PARadigms and PARadoxes
-
Burkle, A., Virag, L., Virag, poly(ADP-ribose): PARadigms and PARadoxes. Mol. Aspects Med. 34 (2013), 1046–1065.
-
(2013)
Mol. Aspects Med.
, vol.34
, pp. 1046-1065
-
-
Burkle, A.1
Virag, L.2
-
56
-
-
63849335919
-
Superoxide, NO, peroxynitrite and PARP in circulatory shock and inflammation
-
Esposito, E., Cuzzocrea, S., Superoxide, NO, peroxynitrite and PARP in circulatory shock and inflammation. Front Biosci. (Landmark Ed) 14 (2009), 263–296.
-
(2009)
Front Biosci. (Landmark Ed)
, vol.14
, pp. 263-296
-
-
Esposito, E.1
Cuzzocrea, S.2
-
57
-
-
84864292111
-
Divalent copper is a potent extracellular blocker for TRPM2 channel
-
Zeng, B., Chen, G.L., Xu, S.Z., Divalent copper is a potent extracellular blocker for TRPM2 channel. Biochem. Biophys. Res. Commun. 424 (2012), 279–284.
-
(2012)
Biochem. Biophys. Res. Commun.
, vol.424
, pp. 279-284
-
-
Zeng, B.1
Chen, G.L.2
Xu, S.Z.3
-
58
-
-
79959873314
-
Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore
-
Yang, W., Manna, P.T., Zou, J., Luo, J., Beech, D.J., Sivaprasadarao, A., Jiang, L.H., Zinc inactivates melastatin transient receptor potential 2 channels via the outer pore. J. Biol. Chem. 286 (2011), 23789–23798.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 23789-23798
-
-
Yang, W.1
Manna, P.T.2
Zou, J.3
Luo, J.4
Beech, D.J.5
Sivaprasadarao, A.6
Jiang, L.H.7
-
59
-
-
0035328671
-
Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins
-
Tsavaler, L., Shapero, M.H., Morkowski, S., Laus, R., Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. Cancer Res 61 (2001), 3760–3769.
-
(2001)
Cancer Res
, vol.61
, pp. 3760-3769
-
-
Tsavaler, L.1
Shapero, M.H.2
Morkowski, S.3
Laus, R.4
-
60
-
-
77956229134
-
Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma
-
Yee, N.S., Zhou, W., Lee, M., Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma. Cancer Lett. 297 (2010), 49–55.
-
(2010)
Cancer Lett.
, vol.297
, pp. 49-55
-
-
Yee, N.S.1
Zhou, W.2
Lee, M.3
-
61
-
-
0037034931
-
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
-
McKemy, D.D., Neuhausser, W.M., Julius, D., Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 416 (2002), 52–58.
-
(2002)
Nature
, vol.416
, pp. 52-58
-
-
McKemy, D.D.1
Neuhausser, W.M.2
Julius, D.3
-
62
-
-
18344386202
-
A TRP channel that senses cold stimuli and menthol
-
Peier, A.M., Moqrich, A., Hergarden, A.C., Reeve, A.J., Andersson, D.A., Story, G.M., Earley, T.J., Dragoni, I., McIntyre, P., Bevan, S., Patapoutian, A., A TRP channel that senses cold stimuli and menthol. Cell 108 (2002), 705–715.
-
(2002)
Cell
, vol.108
, pp. 705-715
-
-
Peier, A.M.1
Moqrich, A.2
Hergarden, A.C.3
Reeve, A.J.4
Andersson, D.A.5
Story, G.M.6
Earley, T.J.7
Dragoni, I.8
McIntyre, P.9
Bevan, S.10
Patapoutian, A.11
-
63
-
-
84904905490
-
Trpm8
-
Almaraz, L., Manenschijn, J.A., de la Pena, E., Viana, F., Trpm8. Handb. Exp. Pharmacol. 222 (2014), 547–579.
-
(2014)
Handb. Exp. Pharmacol.
, vol.222
, pp. 547-579
-
-
Almaraz, L.1
Manenschijn, J.A.2
de la Pena, E.3
Viana, F.4
-
64
-
-
34748877218
-
Characterisation of TRPM8 as a pharmacophore receptor
-
Bodding, M., Wissenbach, U., Flockerzi, V., Characterisation of TRPM8 as a pharmacophore receptor. Cell Calcium 42 (2007), 618–628.
-
(2007)
Cell Calcium
, vol.42
, pp. 618-628
-
-
Bodding, M.1
Wissenbach, U.2
Flockerzi, V.3
-
65
-
-
33846786479
-
Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators
-
Beck, B., Bidaux, G., Bavencoffe, A., Lemonnier, L., Thebault, S., Shuba, Y., Barrit, G., Skryma, R., Prevarskaya, N., Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators. Cell Calcium 41 (2007), 285–294.
-
(2007)
Cell Calcium
, vol.41
, pp. 285-294
-
-
Beck, B.1
Bidaux, G.2
Bavencoffe, A.3
Lemonnier, L.4
Thebault, S.5
Shuba, Y.6
Barrit, G.7
Skryma, R.8
Prevarskaya, N.9
-
66
-
-
4544368241
-
The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel
-
Chuang, H.H., Neuhausser, W.M., Julius, D., The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel. Neuron 43 (2004), 859–869.
-
(2004)
Neuron
, vol.43
, pp. 859-869
-
-
Chuang, H.H.1
Neuhausser, W.M.2
Julius, D.3
-
67
-
-
33645352477
-
High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol
-
Bandell, M., Dubin, A.E., Petrus, M.J., Orth, A., Mathur, J., Hwang, S.W., Patapoutian, A., High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol. Nat. Neurosci. 9 (2006), 493–500.
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 493-500
-
-
Bandell, M.1
Dubin, A.E.2
Petrus, M.J.3
Orth, A.4
Mathur, J.5
Hwang, S.W.6
Patapoutian, A.7
-
68
-
-
0030777012
-
The capsaicin receptor: a heat-activated ion channel in the pain pathway
-
Caterina, M.J., Schumacher, M.A., Tominaga, M., Rosen, T.A., Levine, J.D., Julius, D., The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389 (1997), 816–824.
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
69
-
-
84904901841
-
Trpv1
-
Bevan, S., Quallo, T., Andersson, D.A., Trpv1. Handb Exp Pharmacol 222 (2014), 207–245.
-
(2014)
Handb Exp Pharmacol
, vol.222
, pp. 207-245
-
-
Bevan, S.1
Quallo, T.2
Andersson, D.A.3
-
70
-
-
0036183319
-
Molecular basis for species-specific sensitivity to hot chili peppers
-
Jordt, S.E., Julius, D., Molecular basis for species-specific sensitivity to hot chili peppers. Cell 108 (2002), 421–430.
-
(2002)
Cell
, vol.108
, pp. 421-430
-
-
Jordt, S.E.1
Julius, D.2
-
71
-
-
0033119629
-
A capsaicin-receptor homologue with a high threshold for noxious heat
-
Caterina, M.J., Rosen, T.A., Tominaga, M., Brake, A.J., Julius, D., A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398 (1999), 436–441.
-
(1999)
Nature
, vol.398
, pp. 436-441
-
-
Caterina, M.J.1
Rosen, T.A.2
Tominaga, M.3
Brake, A.J.4
Julius, D.5
-
72
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
Tominaga, M., Caterina, M.J., Malmberg, A.B., Rosen, T.A., Gilbert, H., Skinner, K., Raumann, B.E., Basbaum, A.I., Julius, D., The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21 (1998), 531–543.
-
(1998)
Neuron
, vol.21
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
Rosen, T.A.4
Gilbert, H.5
Skinner, K.6
Raumann, B.E.7
Basbaum, A.I.8
Julius, D.9
-
73
-
-
0033529214
-
Ion channels gated by heat
-
Cesare, P., Moriondo, A., Vellani, V., McNaughton, P.A., Ion channels gated by heat. Proc. Natl. Acad. Sci. U. S. A. 96 (1999), 7658–7663.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 7658-7663
-
-
Cesare, P.1
Moriondo, A.2
Vellani, V.3
McNaughton, P.A.4
-
74
-
-
0036703646
-
Heat-evoked activation of the ion channel, TRPV4
-
Guler, A.D., Lee, H., Iida, T., Shimizu, I., Tominaga, M., Caterina, M., Heat-evoked activation of the ion channel, TRPV4. J. Neurosci. 22 (2002), 6408–6414.
-
(2002)
J. Neurosci.
, vol.22
, pp. 6408-6414
-
-
Guler, A.D.1
Lee, H.2
Iida, T.3
Shimizu, I.4
Tominaga, M.5
Caterina, M.6
-
75
-
-
0037134482
-
Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives
-
Watanabe, H., Davis, J.B., Smart, D., Jerman, J.C., Smith, G.D., Hayes, P., Vriens, J., Cairns, W., Wissenbach, U., Prenen, J., Flockerzi, V., Droogmans, G., Benham, C.D., Nilius, B., Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives. J. Biol. Chem. 277 (2002), 13569–13577.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13569-13577
-
-
Watanabe, H.1
Davis, J.B.2
Smart, D.3
Jerman, J.C.4
Smith, G.D.5
Hayes, P.6
Vriens, J.7
Cairns, W.8
Wissenbach, U.9
Prenen, J.10
Flockerzi, V.11
Droogmans, G.12
Benham, C.D.13
Nilius, B.14
-
76
-
-
84889607320
-
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
-
Liao, M., Cao, E., Julius, D., Cheng, Y., Structure of the TRPV1 ion channel determined by electron cryo-microscopy. Nature 504 (2013), 107–112.
-
(2013)
Nature
, vol.504
, pp. 107-112
-
-
Liao, M.1
Cao, E.2
Julius, D.3
Cheng, Y.4
-
77
-
-
84889594608
-
TRPV1 structures in distinct conformations reveal activation mechanisms
-
Cao, E., Liao, M., Cheng, Y., Julius, D., TRPV1 structures in distinct conformations reveal activation mechanisms. Nature 504 (2013), 113–118.
-
(2013)
Nature
, vol.504
, pp. 113-118
-
-
Cao, E.1
Liao, M.2
Cheng, Y.3
Julius, D.4
-
78
-
-
34250190946
-
The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity
-
Lishko, P.V., Procko, E., Jin, X., Phelps, C.B., Gaudet, R., The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity. Neuron 54 (2007), 905–918.
-
(2007)
Neuron
, vol.54
, pp. 905-918
-
-
Lishko, P.V.1
Procko, E.2
Jin, X.3
Phelps, C.B.4
Gaudet, R.5
-
79
-
-
0032504093
-
Capsaicin sensitivity is associated with the expression of the vanilloid (capsaicin) receptor (VR1) mRNA in adult rat sensory ganglia
-
Helliwell, R.J., McLatchie, L.M., Clarke, M., Winter, J., Bevan, S., McIntyre, P., Capsaicin sensitivity is associated with the expression of the vanilloid (capsaicin) receptor (VR1) mRNA in adult rat sensory ganglia. Neurosci. Lett. 250 (1998), 177–180.
-
(1998)
Neurosci. Lett.
, vol.250
, pp. 177-180
-
-
Helliwell, R.J.1
McLatchie, L.M.2
Clarke, M.3
Winter, J.4
Bevan, S.5
McIntyre, P.6
-
80
-
-
0032970173
-
Vanilloid (Capsaicin) receptors and mechanisms
-
Szallasi, A., Blumberg, P.M., Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol. Rev. 51 (1999), 159–212.
-
(1999)
Pharmacol. Rev.
, vol.51
, pp. 159-212
-
-
Szallasi, A.1
Blumberg, P.M.2
-
81
-
-
0032559217
-
Brain derived neurotrophic factor but not nerve growth factor, regulates capsaicin sensitivity of rat vagal ganglion neurones
-
Winter, J., Brain derived neurotrophic factor but not nerve growth factor, regulates capsaicin sensitivity of rat vagal ganglion neurones. Neurosci. Lett. 241 (1998), 21–24.
-
(1998)
Neurosci. Lett.
, vol.241
, pp. 21-24
-
-
Winter, J.1
-
82
-
-
0037282830
-
Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors
-
Bron, R., Klesse, L.J., Shah, K., Parada, L.F., Winter, J., Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors. Mol. Cell. Neurosci. 22 (2003), 118–132.
-
(2003)
Mol. Cell. Neurosci.
, vol.22
, pp. 118-132
-
-
Bron, R.1
Klesse, L.J.2
Shah, K.3
Parada, L.F.4
Winter, J.5
-
83
-
-
0014796114
-
Stimulation and desensitization of the hypothalamic heat-sensitive structures by capsaicin in rats
-
Jancso-Gabor, A., Szolcsanyi, J., Jancso, N., Stimulation and desensitization of the hypothalamic heat-sensitive structures by capsaicin in rats. J. Physiol. 208 (1970), 449–459.
-
(1970)
J. Physiol.
, vol.208
, pp. 449-459
-
-
Jancso-Gabor, A.1
Szolcsanyi, J.2
Jancso, N.3
-
84
-
-
42449141959
-
Tissue-specific regulation of microvascular diameter: opposite functional roles of neuronal and smooth muscle located vanilloid receptor-1
-
Kark, T., Bagi, Z., Lizanecz, E., Pasztor, E.T., Erdei, N., Czikora, A., Papp, Z., Edes, I., Porszasz, R., Toth, A., Tissue-specific regulation of microvascular diameter: opposite functional roles of neuronal and smooth muscle located vanilloid receptor-1. Mol. Pharmacol. 73 (2008), 1405–1412.
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 1405-1412
-
-
Kark, T.1
Bagi, Z.2
Lizanecz, E.3
Pasztor, E.T.4
Erdei, N.5
Czikora, A.6
Papp, Z.7
Edes, I.8
Porszasz, R.9
Toth, A.10
-
85
-
-
79955732207
-
Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells
-
Cavanaugh, D.J., Chesler, A.T., Jackson, A.C., Sigal, Y.M., Yamanaka, H., Grant, R., O'Donnell, D., Nicoll, R.A., Shah, N.M., Julius, D., Basbaum, A.I., Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cells. J. Neurosci. 31 (2011), 5067–5077.
-
(2011)
J. Neurosci.
, vol.31
, pp. 5067-5077
-
-
Cavanaugh, D.J.1
Chesler, A.T.2
Jackson, A.C.3
Sigal, Y.M.4
Yamanaka, H.5
Grant, R.6
O'Donnell, D.7
Nicoll, R.A.8
Shah, N.M.9
Julius, D.10
Basbaum, A.I.11
-
86
-
-
84911995832
-
Direct evidence for functional TRPV1/TRPA1 heteromers
-
Fischer, M.J., Balasuriya, D., Jeggle, P., Goetze, T.A., McNaughton, P.A., Reeh, P.W., Edwardson, J.M., Direct evidence for functional TRPV1/TRPA1 heteromers. Pflugers Arch. 466 (2014), 2229–2241.
-
(2014)
Pflugers Arch.
, vol.466
, pp. 2229-2241
-
-
Fischer, M.J.1
Balasuriya, D.2
Jeggle, P.3
Goetze, T.A.4
McNaughton, P.A.5
Reeh, P.W.6
Edwardson, J.M.7
-
87
-
-
0034721648
-
Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor
-
Liedtke, W., Choe, Y., Marti-Renom, M.A., Bell, A.M., Denis, C.S., Sali, A., Hudspeth, A.J., Friedman, J.M., Heller, S., Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell 103 (2000), 525–535.
-
(2000)
Cell
, vol.103
, pp. 525-535
-
-
Liedtke, W.1
Choe, Y.2
Marti-Renom, M.A.3
Bell, A.M.4
Denis, C.S.5
Sali, A.6
Hudspeth, A.J.7
Friedman, J.M.8
Heller, S.9
-
88
-
-
0034306198
-
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity
-
Strotmann, R., Harteneck, C., Nunnenmacher, K., Schultz, G., Plant, T.D., OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat. Cell Biol. 2 (2000), 695–702.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 695-702
-
-
Strotmann, R.1
Harteneck, C.2
Nunnenmacher, K.3
Schultz, G.4
Plant, T.D.5
-
89
-
-
0034711336
-
Trp12, a novel Trp related protein from kidney
-
Wissenbach, U., Bodding, M., Freichel, M., Flockerzi, V., Trp12, a novel Trp related protein from kidney. FEBS Lett. 485 (2000), 127–134.
-
(2000)
FEBS Lett.
, vol.485
, pp. 127-134
-
-
Wissenbach, U.1
Bodding, M.2
Freichel, M.3
Flockerzi, V.4
-
90
-
-
73949155532
-
The progesterone receptor regulates the expression of TRPV4 channel
-
Jung, C., Fandos, C., Lorenzo, I.M., Plata, C., Fernandes, J., Gene, G.G., Vazquez, E., Valverde, M.A., The progesterone receptor regulates the expression of TRPV4 channel. Pflugers Arch. 459 (2009), 105–113.
-
(2009)
Pflugers Arch.
, vol.459
, pp. 105-113
-
-
Jung, C.1
Fandos, C.2
Lorenzo, I.M.3
Plata, C.4
Fernandes, J.5
Gene, G.G.6
Vazquez, E.7
Valverde, M.A.8
-
91
-
-
84874115924
-
MicroRNA-203 up-regulates nitric oxide expression in temporomandibular joint chondrocytes via targeting TRPV4
-
Hu, F., Zhu, W., Wang, L., MicroRNA-203 up-regulates nitric oxide expression in temporomandibular joint chondrocytes via targeting TRPV4. Arch. Oral Biol. 58 (2013), 192–199.
-
(2013)
Arch. Oral Biol.
, vol.58
, pp. 192-199
-
-
Hu, F.1
Zhu, W.2
Wang, L.3
-
92
-
-
84877769093
-
Probiotics VSL#3 protect against development of visceral pain in murine model of irritable bowel syndrome
-
Distrutti, E., Cipriani, S., Mencarelli, A., Renga, B., Fiorucci, S., Probiotics VSL#3 protect against development of visceral pain in murine model of irritable bowel syndrome. PLoS One, 8, 2013, e63893.
-
(2013)
PLoS One
, vol.8
, pp. e63893
-
-
Distrutti, E.1
Cipriani, S.2
Mencarelli, A.3
Renga, B.4
Fiorucci, S.5
-
93
-
-
84870835064
-
Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia
-
Segond von Banchet, G., Boettger, M.K., Konig, C., Iwakura, Y., Brauer, R., Schaible, H.G., Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia. Mol. Cell. Neurosci. 52 (2013), 152–160.
-
(2013)
Mol. Cell. Neurosci.
, vol.52
, pp. 152-160
-
-
Segond von Banchet, G.1
Boettger, M.K.2
Konig, C.3
Iwakura, Y.4
Brauer, R.5
Schaible, H.G.6
-
94
-
-
84885143900
-
Increased TRPV4 expression in urinary bladder and lumbosacral dorsal root ganglia in mice with chronic overexpression of NGF in urothelium
-
Girard, B.M., Merrill, L., Malley, S., Vizzard, M.A., Increased TRPV4 expression in urinary bladder and lumbosacral dorsal root ganglia in mice with chronic overexpression of NGF in urothelium. J. Mol. Neurosci.: MN 51 (2013), 602–614.
-
(2013)
J. Mol. Neurosci.: MN
, vol.51
, pp. 602-614
-
-
Girard, B.M.1
Merrill, L.2
Malley, S.3
Vizzard, M.A.4
-
95
-
-
84862992467
-
The increased activity of TRPV4 channel in the astrocytes of the adult rat hippocampus after cerebral hypoxia/ischemia
-
Butenko, O., Dzamba, D., Benesova, J., Honsa, P., Benfenati, V., Rusnakova, V., Ferroni, S., Anderova, M., The increased activity of TRPV4 channel in the astrocytes of the adult rat hippocampus after cerebral hypoxia/ischemia. PLoS One, 7, 2012, e39959.
-
(2012)
PLoS One
, vol.7
, pp. e39959
-
-
Butenko, O.1
Dzamba, D.2
Benesova, J.3
Honsa, P.4
Benfenati, V.5
Rusnakova, V.6
Ferroni, S.7
Anderova, M.8
-
96
-
-
84884254628
-
TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension
-
Xia, Y., Fu, Z., Hu, J., Huang, C., Paudel, O., Cai, S., Liedtke, W., Sham, J.S., TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension. Am. J. Physiol. Cell Physiol. 305 (2013), C704–715.
-
(2013)
Am. J. Physiol. Cell Physiol.
, vol.305
, pp. C704-715
-
-
Xia, Y.1
Fu, Z.2
Hu, J.3
Huang, C.4
Paudel, O.5
Cai, S.6
Liedtke, W.7
Sham, J.S.8
-
97
-
-
65649150431
-
Modulation of the transient receptor potential vanilloid channel TRPV4 by 4 alpha-phorbol esters: a structure-activity study
-
Klausen, T.K., Pagani, A., Minassi, A., Ech-Chahad, A., Prenen, J., Owsianik, G., Hoffmann, E.K., Pedersen, S.F., Appendino, G., Nilius, B., Modulation of the transient receptor potential vanilloid channel TRPV4 by 4 alpha-phorbol esters: a structure-activity study. J. Med. Chem. 52 (2009), 2933–2939.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 2933-2939
-
-
Klausen, T.K.1
Pagani, A.2
Minassi, A.3
Ech-Chahad, A.4
Prenen, J.5
Owsianik, G.6
Hoffmann, E.K.7
Pedersen, S.F.8
Appendino, G.9
Nilius, B.10
-
98
-
-
34250327530
-
Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4
-
Vriens, J., Owsianik, G., Janssens, A., Voets, T., Nilius, B., Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4. J. Biol. Chem. 282 (2007), 12796–12803.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 12796-12803
-
-
Vriens, J.1
Owsianik, G.2
Janssens, A.3
Voets, T.4
Nilius, B.5
-
99
-
-
33749562292
-
Bisandrographolide from Andrographis paniculata activates TRPV4 channels
-
Smith, P.L., Maloney, K.N., Pothen, R.G., Clardy, J., Clapham, D.E., Bisandrographolide from Andrographis paniculata activates TRPV4 channels. J. Biol. Chem. 281 (2006), 29897–29904.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 29897-29904
-
-
Smith, P.L.1
Maloney, K.N.2
Pothen, R.G.3
Clardy, J.4
Clapham, D.E.5
-
100
-
-
84859701223
-
Apigenin, a plant-derived flavone, activates transient receptor potential vanilloid 4 cation channel
-
Ma, X., He, D., Ru, X., Chen, Y., Cai, Y., Bruce, I.C., Xia, Q., Yao, X., Jin, J., Apigenin, a plant-derived flavone, activates transient receptor potential vanilloid 4 cation channel. Br. J. Pharmacol. 166 (2012), 349–358.
-
(2012)
Br. J. Pharmacol.
, vol.166
, pp. 349-358
-
-
Ma, X.1
He, D.2
Ru, X.3
Chen, Y.4
Cai, Y.5
Bruce, I.C.6
Xia, Q.7
Yao, X.8
Jin, J.9
-
101
-
-
84855345743
-
Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation
-
De Petrocellis, L., Orlando, P., Moriello, A.S., Aviello, G., Stott, C., Izzo, A.A., Di Marzo, V., Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. Acta Physiol. (Oxf) 204 (2012), 255–266.
-
(2012)
Acta Physiol. (Oxf)
, vol.204
, pp. 255-266
-
-
De Petrocellis, L.1
Orlando, P.2
Moriello, A.S.3
Aviello, G.4
Stott, C.5
Izzo, A.A.6
Di Marzo, V.7
-
102
-
-
0043267987
-
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
-
Watanabe, H., Vriens, J., Prenen, J., Droogmans, G., Voets, T., Nilius, B., Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature 424 (2003), 434–438.
-
(2003)
Nature
, vol.424
, pp. 434-438
-
-
Watanabe, H.1
Vriens, J.2
Prenen, J.3
Droogmans, G.4
Voets, T.5
Nilius, B.6
-
103
-
-
78650479042
-
Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis
-
Everaerts, W., Zhen, X., Ghosh, D., Vriens, J., Gevaert, T., Gilbert, J.P., Hayward, N.J., McNamara, C.R., Xue, F., Moran, M.M., Strassmaier, T., Uykal, E., Owsianik, G., Vennekens, R., De Ridder, D., Nilius, B., Fanger, C.M., Voets, T., Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 19084–19089.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 19084-19089
-
-
Everaerts, W.1
Zhen, X.2
Ghosh, D.3
Vriens, J.4
Gevaert, T.5
Gilbert, J.P.6
Hayward, N.J.7
McNamara, C.R.8
Xue, F.9
Moran, M.M.10
Strassmaier, T.11
Uykal, E.12
Owsianik, G.13
Vennekens, R.14
De Ridder, D.15
Nilius, B.16
Fanger, C.M.17
Voets, T.18
-
104
-
-
84869141720
-
An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure
-
Thorneloe, K.S., Cheung, M., Bao, W., Alsaid, H., Lenhard, S., Jian, M.Y., Costell, M., Maniscalco-Hauk, K., Krawiec, J.A., Olzinski, A., Gordon, E., Lozinskaya, I., Elefante, L., Qin, P., Matasic, D.S., James, C., Tunstead, J., Donovan, B., Kallal, L., Waszkiewicz, A., Vaidya, K., Davenport, E.A., Larkin, J., Burgert, M., Casillas, L.N., Marquis, R.W., Ye, G., Eidam, H.S., Goodman, K.B., Toomey, J.R., Roethke, T.J., Jucker, B.M., Schnackenberg, C.G., Townsley, M.I., Lepore, J.J., Willette, R.N., An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure. Sci. Trans. Med., 4, 2012, 159ra148.
-
(2012)
Sci. Trans. Med.
, vol.4
, pp. 159ra148
-
-
Thorneloe, K.S.1
Cheung, M.2
Bao, W.3
Alsaid, H.4
Lenhard, S.5
Jian, M.Y.6
Costell, M.7
Maniscalco-Hauk, K.8
Krawiec, J.A.9
Olzinski, A.10
Gordon, E.11
Lozinskaya, I.12
Elefante, L.13
Qin, P.14
Matasic, D.S.15
James, C.16
Tunstead, J.17
Donovan, B.18
Kallal, L.19
Waszkiewicz, A.20
Vaidya, K.21
Davenport, E.A.22
Larkin, J.23
Burgert, M.24
Casillas, L.N.25
Marquis, R.W.26
Ye, G.27
Eidam, H.S.28
Goodman, K.B.29
Toomey, J.R.30
Roethke, T.J.31
Jucker, B.M.32
Schnackenberg, C.G.33
Townsley, M.I.34
Lepore, J.J.35
Willette, R.N.36
more..
-
105
-
-
84904359102
-
TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury, American journal of physiology
-
Balakrishna, S., Song, W., Achanta, S., Doran, S.F., Liu, B., Kaelberer, M.M., Yu, Z., Sui, A., Cheung, M., Leishman, E., Eidam, H.S., Ye, G., Willette, R.N., Thorneloe, K.S., Bradshaw, H.B., Matalon, S., Jordt, S.E., TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury, American journal of physiology. Lung Cell. Mol. Physiol. 307 (2014), L158–172.
-
(2014)
Lung Cell. Mol. Physiol.
, vol.307
, pp. L158-172
-
-
Balakrishna, S.1
Song, W.2
Achanta, S.3
Doran, S.F.4
Liu, B.5
Kaelberer, M.M.6
Yu, Z.7
Sui, A.8
Cheung, M.9
Leishman, E.10
Eidam, H.S.11
Ye, G.12
Willette, R.N.13
Thorneloe, K.S.14
Bradshaw, H.B.15
Matalon, S.16
Jordt, S.E.17
-
106
-
-
84963830297
-
Role of transient receptor potential vanilloid 4 in neutrophil activation and acute lung injury
-
Yin, J., Michalick, L., Tang, C., Tabuchi, A., Goldenberg, N., Dan, Q., Awwad, K., Wang, L., Erfinanda, L., Nouailles, G., Witzenrath, M., Vogelzang, A., Lv, L., Lee, W.L., Zhang, H., Rotstein, O., Kapus, A., Szaszi, K., Fleming, I., Liedtke, W.B., Kuppe, H., Kuebler, W.M., Role of transient receptor potential vanilloid 4 in neutrophil activation and acute lung injury. Am. J. Respir. Cell Mol. Biol. 54 (2016), 370–383.
-
(2016)
Am. J. Respir. Cell Mol. Biol.
, vol.54
, pp. 370-383
-
-
Yin, J.1
Michalick, L.2
Tang, C.3
Tabuchi, A.4
Goldenberg, N.5
Dan, Q.6
Awwad, K.7
Wang, L.8
Erfinanda, L.9
Nouailles, G.10
Witzenrath, M.11
Vogelzang, A.12
Lv, L.13
Lee, W.L.14
Zhang, H.15
Rotstein, O.16
Kapus, A.17
Szaszi, K.18
Fleming, I.19
Liedtke, W.B.20
Kuppe, H.21
Kuebler, W.M.22
more..
-
107
-
-
84655161875
-
Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben
-
Bang, S., Yang, T.J., Yoo, S., Heo, T.H., Hwang, S.W., Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben. Neurosci. Lett. 506 (2012), 297–302.
-
(2012)
Neurosci. Lett.
, vol.506
, pp. 297-302
-
-
Bang, S.1
Yang, T.J.2
Yoo, S.3
Heo, T.H.4
Hwang, S.W.5
-
108
-
-
85012271387
-
The role and importance of club cells (Clara cells) in the pathogenesis of some respiratory diseases
-
Rokicki, W., Rokicki, M., Wojtacha, J., Dzeljijli, A., The role and importance of club cells (Clara cells) in the pathogenesis of some respiratory diseases. Kardiochirurgia i torakochirurgia polska = Polish J. Cardio-Thoracic Surg. 13 (2016), 26–30.
-
(2016)
Kardiochirurgia i torakochirurgia polska = Polish J. Cardio-Thoracic Surg.
, vol.13
, pp. 26-30
-
-
Rokicki, W.1
Rokicki, M.2
Wojtacha, J.3
Dzeljijli, A.4
-
110
-
-
84871665278
-
Occupational asthma
-
Kenyon, N.J., Morrissey, B.M., Schivo, M., Albertson, T.E., Occupational asthma. Clin. Rev. Allergy Immunol. 43 (2012), 3–13.
-
(2012)
Clin. Rev. Allergy Immunol.
, vol.43
, pp. 3-13
-
-
Kenyon, N.J.1
Morrissey, B.M.2
Schivo, M.3
Albertson, T.E.4
-
111
-
-
39049170984
-
Global strategy for asthma management and prevention: GINA executive summary
-
Bateman, E.D., Hurd, S.S., Barnes, P.J., Bousquet, J., Drazen, J.M., FitzGerald, M., Gibson, P., Ohta, K., O'Byrne, P., Pedersen, S.E., Pizzichini, E., Sullivan, S.D., Wenzel, S.E., Zar, H.J., Global strategy for asthma management and prevention: GINA executive summary. Eur. Respir. J. 31 (2008), 143–178.
-
(2008)
Eur. Respir. J.
, vol.31
, pp. 143-178
-
-
Bateman, E.D.1
Hurd, S.S.2
Barnes, P.J.3
Bousquet, J.4
Drazen, J.M.5
FitzGerald, M.6
Gibson, P.7
Ohta, K.8
O'Byrne, P.9
Pedersen, S.E.10
Pizzichini, E.11
Sullivan, S.D.12
Wenzel, S.E.13
Zar, H.J.14
-
112
-
-
84875225940
-
Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease
-
Barnes, P.J., Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease. J. Allergy Clin. Immunol. 131 (2013), 636–645.
-
(2013)
J. Allergy Clin. Immunol.
, vol.131
, pp. 636-645
-
-
Barnes, P.J.1
-
113
-
-
79953726304
-
Glucocorticosteroids: current and future directions
-
Barnes, P.J., Glucocorticosteroids: current and future directions. Br. J. Pharmacol. 163 (2011), 29–43.
-
(2011)
Br. J. Pharmacol.
, vol.163
, pp. 29-43
-
-
Barnes, P.J.1
-
114
-
-
79951675683
-
Emphysema and chronic obstructive pulmonary disease in coal miners
-
Santo Tomas, L.H., Emphysema and chronic obstructive pulmonary disease in coal miners. Curr. Opin. Pulm. Med. 17 (2011), 123–125.
-
(2011)
Curr. Opin. Pulm. Med.
, vol.17
, pp. 123-125
-
-
Santo Tomas, L.H.1
-
115
-
-
0034126440
-
Smoking and chronic obstructive pulmonary disease
-
(viii)
-
Sethi, J.M., Rochester, C.L., Smoking and chronic obstructive pulmonary disease. Clin. Chest Med. 21 (2000), 67–86 (viii).
-
(2000)
Clin. Chest Med.
, vol.21
, pp. 67-86
-
-
Sethi, J.M.1
Rochester, C.L.2
-
116
-
-
69149102202
-
Chronic obstructive pulmonary disease in non-smokers
-
Salvi, S.S., Barnes, P.J., Chronic obstructive pulmonary disease in non-smokers. Lancet 374 (2009), 733–743.
-
(2009)
Lancet
, vol.374
, pp. 733-743
-
-
Salvi, S.S.1
Barnes, P.J.2
-
117
-
-
82755161052
-
Idiopathic pulmonary fibrosis
-
King, T.E. Jr., Pardo, A., Selman, M., Idiopathic pulmonary fibrosis. Lancet 378 (2011), 1949–1961.
-
(2011)
Lancet
, vol.378
, pp. 1949-1961
-
-
King, T.E.1
Pardo, A.2
Selman, M.3
-
118
-
-
0035895243
-
Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy
-
Selman, M., King, T.E., Pardo, A., Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann. Intern. Med. 134 (2001), 136–151.
-
(2001)
Ann. Intern. Med.
, vol.134
, pp. 136-151
-
-
Selman, M.1
King, T.E.2
Pardo, A.3
-
119
-
-
84859073207
-
Recent developments in myofibroblast biology: paradigms for connective tissue remodeling
-
Hinz, B., Phan, S.H., Thannickal, V.J., Prunotto, M., Desmouliere, A., Varga, J., De Wever, O., Mareel, M., Gabbiani, G., Recent developments in myofibroblast biology: paradigms for connective tissue remodeling. Am. J. Pathol. 180 (2012), 1340–1355.
-
(2012)
Am. J. Pathol.
, vol.180
, pp. 1340-1355
-
-
Hinz, B.1
Phan, S.H.2
Thannickal, V.J.3
Prunotto, M.4
Desmouliere, A.5
Varga, J.6
De Wever, O.7
Mareel, M.8
Gabbiani, G.9
-
120
-
-
84886304100
-
Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis
-
Hung, C., Linn, G., Chow, Y.H., Kobayashi, A., Mittelsteadt, K., Altemeier, W.A., Gharib, S.A., Schnapp, L.M., Duffield, J.S., Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 188 (2013), 820–830.
-
(2013)
Am. J. Respir. Crit. Care Med.
, vol.188
, pp. 820-830
-
-
Hung, C.1
Linn, G.2
Chow, Y.H.3
Kobayashi, A.4
Mittelsteadt, K.5
Altemeier, W.A.6
Gharib, S.A.7
Schnapp, L.M.8
Duffield, J.S.9
-
121
-
-
33748375828
-
Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
-
Kim, K.K., Kugler, M.C., Wolters, P.J., Robillard, L., Galvez, M.G., Brumwell, A.N., Sheppard, D., Chapman, H.A., Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 13180–13185.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 13180-13185
-
-
Kim, K.K.1
Kugler, M.C.2
Wolters, P.J.3
Robillard, L.4
Galvez, M.G.5
Brumwell, A.N.6
Sheppard, D.7
Chapman, H.A.8
-
122
-
-
80052196384
-
Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress
-
Tanjore, H., Cheng, D.S., Degryse, A.L., Zoz, D.F., Abdolrasulnia, R., Lawson, W.E., Blackwell, T.S., Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress. J. Biol. Chem. 286 (2011), 30972–30980.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 30972-30980
-
-
Tanjore, H.1
Cheng, D.S.2
Degryse, A.L.3
Zoz, D.F.4
Abdolrasulnia, R.5
Lawson, W.E.6
Blackwell, T.S.7
-
123
-
-
84855375381
-
Parenchymal trafficking of pleural mesothelial cells in idiopathic pulmonary fibrosis
-
Mubarak, K.K., Montes-Worboys, A., Regev, D., Nasreen, N., Mohammed, K.A., Faruqi, I., Hensel, E., Baz, M.A., Akindipe, O.A., Fernandez-Bussy, S., Nathan, S.D., Antony, V.B., Parenchymal trafficking of pleural mesothelial cells in idiopathic pulmonary fibrosis. Eur. Respir. J. 39 (2012), 133–140.
-
(2012)
Eur. Respir. J.
, vol.39
, pp. 133-140
-
-
Mubarak, K.K.1
Montes-Worboys, A.2
Regev, D.3
Nasreen, N.4
Mohammed, K.A.5
Faruqi, I.6
Hensel, E.7
Baz, M.A.8
Akindipe, O.A.9
Fernandez-Bussy, S.10
Nathan, S.D.11
Antony, V.B.12
-
124
-
-
84939524556
-
Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/beta-catenin-driven trans-differentiation of murine alveolar epithelial cells
-
Mutze, K., Vierkotten, S., Milosevic, J., Eickelberg, O., Konigshoff, M., Enolase 1 (ENO1) and protein disulfide-isomerase associated 3 (PDIA3) regulate Wnt/beta-catenin-driven trans-differentiation of murine alveolar epithelial cells. Dis. Models Mech. 8 (2015), 877–890.
-
(2015)
Dis. Models Mech.
, vol.8
, pp. 877-890
-
-
Mutze, K.1
Vierkotten, S.2
Milosevic, J.3
Eickelberg, O.4
Konigshoff, M.5
-
125
-
-
84889272385
-
Respiratory toxicity
-
R.C. Smart E. Hodgson John Wiley & Sons Hoboken, N.J
-
Bonner, C., Respiratory toxicity. Smart, R.C., Hodgson, E., (eds.) Molecular and Biochemical Toxicology, 2008, John Wiley & Sons, Hoboken, N.J, 639–670.
-
(2008)
Molecular and Biochemical Toxicology
, pp. 639-670
-
-
Bonner, C.1
-
126
-
-
84898041279
-
Respirationstrakt
-
H. Marquardt S. Schäfer Wissenschaftliche Verlagsgesellschaft mbH Stuttgart
-
Muhle, H., McClellan, R., Respirationstrakt. Marquardt, H., Schäfer, S., (eds.) Lehrbuch der Toxikologie, 2003, Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, 365–382.
-
(2003)
Lehrbuch der Toxikologie
, pp. 365-382
-
-
Muhle, H.1
McClellan, R.2
-
127
-
-
15544377977
-
TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity
-
Andrade, Y.N., Fernandes, J., Vazquez, E., Fernandez-Fernandez, J.M., Arniges, M., Sanchez, T.M., Villalon, M., Valverde, M.A., TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity. J. Cell Biol. 168 (2005), 869–874.
-
(2005)
J. Cell Biol.
, vol.168
, pp. 869-874
-
-
Andrade, Y.N.1
Fernandes, J.2
Vazquez, E.3
Fernandez-Fernandez, J.M.4
Arniges, M.5
Sanchez, T.M.6
Villalon, M.7
Valverde, M.A.8
-
128
-
-
37649008470
-
Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion
-
Gradilone, S.A., Masyuk, A.I., Splinter, P.L., Banales, J.M., Huang, B.Q., Tietz, P.S., Masyuk, T.V., Larusso, N.F., Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion. Proc. Natl. Acad. Sci. U. S. A. 104 (2007), 19138–19143.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 19138-19143
-
-
Gradilone, S.A.1
Masyuk, A.I.2
Splinter, P.L.3
Banales, J.M.4
Huang, B.Q.5
Tietz, P.S.6
Masyuk, T.V.7
Larusso, N.F.8
-
129
-
-
50449106167
-
TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells
-
Lorenzo, I.M., Liedtke, W., Sanderson, M.J., Valverde, M.A., TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 12611–12616.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 12611-12616
-
-
Lorenzo, I.M.1
Liedtke, W.2
Sanderson, M.J.3
Valverde, M.A.4
-
130
-
-
79960694399
-
Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia
-
Seminario-Vidal, L., Okada, S.F., Sesma, J.I., Kreda, S.M., van Heusden, C.A., Zhu, Y., Jones, L.C., O'Neal, W.K., Penuela, S., Laird, D.W., Boucher, R.C., Lazarowski, E.R., Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia. J. Biol. Chem. 286 (2011), 26277–26286.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 26277-26286
-
-
Seminario-Vidal, L.1
Okada, S.F.2
Sesma, J.I.3
Kreda, S.M.4
van Heusden, C.A.5
Zhu, Y.6
Jones, L.C.7
O'Neal, W.K.8
Penuela, S.9
Laird, D.W.10
Boucher, R.C.11
Lazarowski, E.R.12
-
131
-
-
77957101431
-
Extracellular ATP is a danger signal activating P2 × 7 receptor in lung inflammation and fibrosis
-
Riteau, N., Gasse, P., Fauconnier, L., Gombault, A., Couegnat, M., Fick, L., Kanellopoulos, J., Quesniaux, V.F., Marchand-Adam, S., Crestani, B., Ryffel, B., Couillin, I., Extracellular ATP is a danger signal activating P2 × 7 receptor in lung inflammation and fibrosis. Am. J. Respir. Crit. Care Med. 182 (2010), 774–783.
-
(2010)
Am. J. Respir. Crit. Care Med.
, vol.182
, pp. 774-783
-
-
Riteau, N.1
Gasse, P.2
Fauconnier, L.3
Gombault, A.4
Couegnat, M.5
Fick, L.6
Kanellopoulos, J.7
Quesniaux, V.F.8
Marchand-Adam, S.9
Crestani, B.10
Ryffel, B.11
Couillin, I.12
-
132
-
-
57749111494
-
Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control
-
Bessac, B.F., Jordt, S.E., Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control. Physiology 23 (2008), 360–370.
-
(2008)
Physiology
, vol.23
, pp. 360-370
-
-
Bessac, B.F.1
Jordt, S.E.2
-
133
-
-
77957894138
-
Sensory detection and responses to toxic gases: mechanisms, health effects, and countermeasures
-
Bessac, B.F., Jordt, S.E., Sensory detection and responses to toxic gases: mechanisms, health effects, and countermeasures. Proc. Am. Thorac. Soc. 7 (2010), 269–277.
-
(2010)
Proc. Am. Thorac. Soc.
, vol.7
, pp. 269-277
-
-
Bessac, B.F.1
Jordt, S.E.2
-
134
-
-
84900799033
-
Transient receptor potential (TRP) channels in the airway: role in airway disease
-
Grace, M.S., Baxter, M., Dubuis, E., Birrell, M.A., Belvisi, M.G., Transient receptor potential (TRP) channels in the airway: role in airway disease. Br. J. Pharmacol. 171 (2014), 2593–2607.
-
(2014)
Br. J. Pharmacol.
, vol.171
, pp. 2593-2607
-
-
Grace, M.S.1
Baxter, M.2
Dubuis, E.3
Birrell, M.A.4
Belvisi, M.G.5
-
135
-
-
84903842029
-
CHEST launches a new era with a new design
-
Irwin, R.S., Tedeschi, V., Rice, J., French, C.T., Welch, S.J., CHEST launches a new era with a new design. Chest 146 (2014), 1–4.
-
(2014)
Chest
, vol.146
, pp. 1-4
-
-
Irwin, R.S.1
Tedeschi, V.2
Rice, J.3
French, C.T.4
Welch, S.J.5
-
136
-
-
84864288800
-
Comparison of TRPA1-versus TRPV1-mediated cough in guinea pigs
-
Brozmanova, M., Mazurova, L., Ru, F., Tatar, M., Kollarik, M., Comparison of TRPA1-versus TRPV1-mediated cough in guinea pigs. Eur. J. Pharmacol. 689 (2012), 211–218.
-
(2012)
Eur. J. Pharmacol.
, vol.689
, pp. 211-218
-
-
Brozmanova, M.1
Mazurova, L.2
Ru, F.3
Tatar, M.4
Kollarik, M.5
-
137
-
-
70350543343
-
Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents
-
Andre, E., Gatti, R., Trevisani, M., Preti, D., Baraldi, P.G., Patacchini, R., Geppetti, P., Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents. Br. J. Pharmacol. 158 (2009), 1621–1628.
-
(2009)
Br. J. Pharmacol.
, vol.158
, pp. 1621-1628
-
-
Andre, E.1
Gatti, R.2
Trevisani, M.3
Preti, D.4
Baraldi, P.G.5
Patacchini, R.6
Geppetti, P.7
-
138
-
-
70449534119
-
TRPA1 agonists evoke coughing in guinea pig and human volunteers
-
Birrell, M.A., Belvisi, M.G., Grace, M., Sadofsky, L., Faruqi, S., Hele, D.J., Maher, S.A., Freund-Michel, V., Morice, A.H., TRPA1 agonists evoke coughing in guinea pig and human volunteers. Am. J. Respir. Crit. Care Med. 180 (2009), 1042–1047.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.180
, pp. 1042-1047
-
-
Birrell, M.A.1
Belvisi, M.G.2
Grace, M.3
Sadofsky, L.4
Faruqi, S.5
Hele, D.J.6
Maher, S.A.7
Freund-Michel, V.8
Morice, A.H.9
-
139
-
-
3042684373
-
Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs
-
Canning, B.J., Mazzone, S.B., Meeker, S.N., Mori, N., Reynolds, S.M., Undem, B.J., Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs. J. Physiol. 557 (2004), 543–558.
-
(2004)
J. Physiol.
, vol.557
, pp. 543-558
-
-
Canning, B.J.1
Mazzone, S.B.2
Meeker, S.N.3
Mori, N.4
Reynolds, S.M.5
Undem, B.J.6
-
140
-
-
84866780647
-
Antitussive effects of the peripherally restricted GABAB receptor agonist lesogaberan in guinea pigs: comparison to baclofen and other GABAB receptor-selective agonists
-
Canning, B.J., Mori, N., Lehmann, A., Antitussive effects of the peripherally restricted GABAB receptor agonist lesogaberan in guinea pigs: comparison to baclofen and other GABAB receptor-selective agonists. Cough, 8, 2012, 7.
-
(2012)
Cough
, vol.8
, pp. 7
-
-
Canning, B.J.1
Mori, N.2
Lehmann, A.3
-
141
-
-
84866090064
-
Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin
-
Grace, M., Birrell, M.A., Dubuis, E., Maher, S.A., Belvisi, M.G., Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin. Thorax 67 (2012), 891–900.
-
(2012)
Thorax
, vol.67
, pp. 891-900
-
-
Grace, M.1
Birrell, M.A.2
Dubuis, E.3
Maher, S.A.4
Belvisi, M.G.5
-
142
-
-
48949120476
-
Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal
-
Taylor-Clark, T.E., McAlexander, M.A., Nassenstein, C., Sheardown, S.A., Wilson, S., Thornton, J., Carr, M.J., Undem, B.J., Relative contributions of TRPA1 and TRPV1 channels in the activation of vagal bronchopulmonary C-fibres by the endogenous autacoid 4-oxononenal. J. Physiol. 586 (2008), 3447–3459.
-
(2008)
J. Physiol.
, vol.586
, pp. 3447-3459
-
-
Taylor-Clark, T.E.1
McAlexander, M.A.2
Nassenstein, C.3
Sheardown, S.A.4
Wilson, S.5
Thornton, J.6
Carr, M.J.7
Undem, B.J.8
-
143
-
-
40949085115
-
Expression and function of the ion channel TRPA1 in vagal afferent nerves innervating mouse lungs
-
Nassenstein, C., Kwong, K., Taylor-Clark, T., Kollarik, M., Macglashan, D.M., Braun, A., Undem, B.J., Expression and function of the ion channel TRPA1 in vagal afferent nerves innervating mouse lungs. J. Physiol. 586 (2008), 1595–1604.
-
(2008)
J. Physiol.
, vol.586
, pp. 1595-1604
-
-
Nassenstein, C.1
Kwong, K.2
Taylor-Clark, T.3
Kollarik, M.4
Macglashan, D.M.5
Braun, A.6
Undem, B.J.7
-
144
-
-
33646045075
-
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
-
Bautista, D.M., Jordt, S.E., Nikai, T., Tsuruda, P.R., Read, A.J., Poblete, J., Yamoah, E.N., Basbaum, A.I., Julius, D., TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 124 (2006), 1269–1282.
-
(2006)
Cell
, vol.124
, pp. 1269-1282
-
-
Bautista, D.M.1
Jordt, S.E.2
Nikai, T.3
Tsuruda, P.R.4
Read, A.J.5
Poblete, J.6
Yamoah, E.N.7
Basbaum, A.I.8
Julius, D.9
-
145
-
-
84891888332
-
Modulation of transient receptor vanilloid 1 activity by transient receptor potential ankyrin 1
-
Spahn, V., Stein, C., Zollner, C., Modulation of transient receptor vanilloid 1 activity by transient receptor potential ankyrin 1. Mol. Pharmacol. 85 (2014), 335–344.
-
(2014)
Mol. Pharmacol.
, vol.85
, pp. 335-344
-
-
Spahn, V.1
Stein, C.2
Zollner, C.3
-
146
-
-
84903709164
-
Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: a double-blind randomized controlled trial
-
Khalid, R., Murdoch, A., Newlands, K., Smart, A., Kelsall, K., Holt, R., Dockry, A., Woodcock, J.A., Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: a double-blind randomized controlled trial. J. Allergy Clin. Immunol. 134 (2014), 56–62.
-
(2014)
J. Allergy Clin. Immunol.
, vol.134
, pp. 56-62
-
-
Khalid, R.1
Murdoch, A.2
Newlands, K.3
Smart, A.4
Kelsall, K.5
Holt, R.6
Dockry, A.7
Woodcock, J.A.8
-
147
-
-
84962198276
-
Role of reactive oxygen species and TRP channels in the cough reflex
-
Taylor-Clark, T.E., Role of reactive oxygen species and TRP channels in the cough reflex. Cell Calcium 60 (2016), 155–162.
-
(2016)
Cell Calcium
, vol.60
, pp. 155-162
-
-
Taylor-Clark, T.E.1
-
148
-
-
84875237220
-
Emerging mechanistic targets in lung injury induced by combustion-generated particles
-
Fariss, M.W., Gilmour, M.I., Reilly, C.A., Liedtke, W., Ghio, A.J., Emerging mechanistic targets in lung injury induced by combustion-generated particles. Toxicol. Sci. 132 (2013), 253–267.
-
(2013)
Toxicol. Sci.
, vol.132
, pp. 253-267
-
-
Fariss, M.W.1
Gilmour, M.I.2
Reilly, C.A.3
Liedtke, W.4
Ghio, A.J.5
-
149
-
-
84884295530
-
Toxic inhalation injury and toxic industrial chemicals
-
M. Lenhart Office of the General Surgeon Washington
-
Tuorinsky, S., Sciuto, A., Toxic inhalation injury and toxic industrial chemicals. Lenhart, M., (eds.) Medical Aspects of Chemical Warfare, 2008, Office of the General Surgeon, Washington, 339–370.
-
(2008)
Medical Aspects of Chemical Warfare
, pp. 339-370
-
-
Tuorinsky, S.1
Sciuto, A.2
-
150
-
-
0033036642
-
Upper and lower airway sequelae of irritant inhalations
-
Shusterman, D., Upper and lower airway sequelae of irritant inhalations. Clin. Pulmonary Med. 6 (1999), 18–31.
-
(1999)
Clin. Pulmonary Med.
, vol.6
, pp. 18-31
-
-
Shusterman, D.1
-
151
-
-
85008894514
-
Role of TRPA1 in acute cardiopulmonary toxicity of inhaled acrolein
-
Conklin, D.J., Haberzettl, P., Jagatheesan, G., Kong, M., Hoyle, G.W., Role of TRPA1 in acute cardiopulmonary toxicity of inhaled acrolein. Toxicol. Appl. Pharmacol. 324 (2017), 61–72.
-
(2017)
Toxicol. Appl. Pharmacol.
, vol.324
, pp. 61-72
-
-
Conklin, D.J.1
Haberzettl, P.2
Jagatheesan, G.3
Kong, M.4
Hoyle, G.W.5
-
152
-
-
38949113159
-
Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease
-
Stevens, J.F., Maier, C.S., Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease. Mol. Nutr. Food Res. 52 (2008), 7–25.
-
(2008)
Mol. Nutr. Food Res.
, vol.52
, pp. 7-25
-
-
Stevens, J.F.1
Maier, C.S.2
-
153
-
-
33846692923
-
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
-
Macpherson, L.J., Dubin, A.E., Evans, M.J., Marr, F., Schultz, P.G., Cravatt, B.F., Patapoutian, A., Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature 445 (2007), 541–545.
-
(2007)
Nature
, vol.445
, pp. 541-545
-
-
Macpherson, L.J.1
Dubin, A.E.2
Evans, M.J.3
Marr, F.4
Schultz, P.G.5
Cravatt, B.F.6
Patapoutian, A.7
-
154
-
-
84856409044
-
TRPA1 antagonists as potential analgesic drugs
-
Andrade, E.L., Meotti, F.C., Calixto, J.B., TRPA1 antagonists as potential analgesic drugs. Pharmacol. Ther. 133 (2012), 189–204.
-
(2012)
Pharmacol. Ther.
, vol.133
, pp. 189-204
-
-
Andrade, E.L.1
Meotti, F.C.2
Calixto, J.B.3
-
155
-
-
0015688843
-
Sensory irritation by airborne chemicals
-
Alarie, Y., Sensory irritation by airborne chemicals. CRC Crit. Rev. Toxicol. 2 (1973), 299–363.
-
(1973)
CRC Crit. Rev. Toxicol.
, vol.2
, pp. 299-363
-
-
Alarie, Y.1
-
156
-
-
84940585274
-
Activation of the chemosensing transient receptor potential channel A1 (TRPA1) by alkylating agents
-
Stenger, B., Zehfuss, F., Muckter, H., Schmidt, A., Balszuweit, F., Schafer, E., Buch, T., Gudermann, T., Thiermann, H., Steinritz, D., Activation of the chemosensing transient receptor potential channel A1 (TRPA1) by alkylating agents. Arch. Toxicol. 89 (2015), 1631–1643.
-
(2015)
Arch. Toxicol.
, vol.89
, pp. 1631-1643
-
-
Stenger, B.1
Zehfuss, F.2
Muckter, H.3
Schmidt, A.4
Balszuweit, F.5
Schafer, E.6
Buch, T.7
Gudermann, T.8
Thiermann, H.9
Steinritz, D.10
-
157
-
-
84991049630
-
N-Acetyl-L-cysteine inhibits sulfur mustard-induced and TRPA1-dependent calcium influx
-
Stenger, B., Popp, T., John, H., Siegert, M., Tsoutsoulopoulos, A., Schmidt, A., Muckter, H., Gudermann, T., Thiermann, H., Steinritz, D., N-Acetyl-L-cysteine inhibits sulfur mustard-induced and TRPA1-dependent calcium influx. Arch. Toxicol. 91 (2017), 2179–2189.
-
(2017)
Arch. Toxicol.
, vol.91
, pp. 2179-2189
-
-
Stenger, B.1
Popp, T.2
John, H.3
Siegert, M.4
Tsoutsoulopoulos, A.5
Schmidt, A.6
Muckter, H.7
Gudermann, T.8
Thiermann, H.9
Steinritz, D.10
-
158
-
-
84913549281
-
TRPV4: an exciting new target to promote alveolocapillary barrier function, American journal of physiology
-
Morty, R.E., Kuebler, W.M., TRPV4: an exciting new target to promote alveolocapillary barrier function, American journal of physiology. Lung Cell. Mol. Physiol. 307 (2014), L817–821.
-
(2014)
Lung Cell. Mol. Physiol.
, vol.307
, pp. L817-821
-
-
Morty, R.E.1
Kuebler, W.M.2
-
159
-
-
84874657531
-
Opportunistic activation of TRP receptors by endogenous lipids: exploiting lipidomics to understand TRP receptor cellular communication
-
Bradshaw, H.B., Raboune, S., Hollis, J.L., Opportunistic activation of TRP receptors by endogenous lipids: exploiting lipidomics to understand TRP receptor cellular communication. Life Sci. 92 (2013), 404–409.
-
(2013)
Life Sci.
, vol.92
, pp. 404-409
-
-
Bradshaw, H.B.1
Raboune, S.2
Hollis, J.L.3
-
160
-
-
33746657575
-
A FAAH-regulated class of N-acyl taurines that activates TRP ion channels
-
Saghatelian, A., McKinney, M.K., Bandell, M., Patapoutian, A., Cravatt, B.F., A FAAH-regulated class of N-acyl taurines that activates TRP ion channels. Biochemistry 45 (2006), 9007–9015.
-
(2006)
Biochemistry
, vol.45
, pp. 9007-9015
-
-
Saghatelian, A.1
McKinney, M.K.2
Bandell, M.3
Patapoutian, A.4
Cravatt, B.F.5
-
161
-
-
84867801052
-
Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates
-
Groot-Kormelink, P.J., Fawcett, L., Wright, P.D., Gosling, M., Kent, T.C., Quantitative GPCR and ion channel transcriptomics in primary alveolar macrophages and macrophage surrogates. BMC. Immunol., 13, 2012, 57.
-
(2012)
BMC. Immunol.
, vol.13
, pp. 57
-
-
Groot-Kormelink, P.J.1
Fawcett, L.2
Wright, P.D.3
Gosling, M.4
Kent, T.C.5
-
162
-
-
84863143271
-
Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material
-
Deering-Rice, C.E., Johansen, M.E., Roberts, J.K., Thomas, K.C., Romero, E.G., Lee, J., Yost, G.S., Veranth, J.M., Reilly, C.A., Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material. Mol. Pharmacol. 81 (2012), 411–419.
-
(2012)
Mol. Pharmacol.
, vol.81
, pp. 411-419
-
-
Deering-Rice, C.E.1
Johansen, M.E.2
Roberts, J.K.3
Thomas, K.C.4
Romero, E.G.5
Lee, J.6
Yost, G.S.7
Veranth, J.M.8
Reilly, C.A.9
-
163
-
-
79959475019
-
Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP
-
Deering-Rice, C.E., Romero, E.G., Shapiro, D., Hughen, R.W., Light, A.R., Yost, G.S., Veranth, J.M., Reilly, C.A., Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP. Chem. Res. Toxicol. 24 (2011), 950–959.
-
(2011)
Chem. Res. Toxicol.
, vol.24
, pp. 950-959
-
-
Deering-Rice, C.E.1
Romero, E.G.2
Shapiro, D.3
Hughen, R.W.4
Light, A.R.5
Yost, G.S.6
Veranth, J.M.7
Reilly, C.A.8
-
164
-
-
84964786368
-
TRP channels and traffic-related environmental pollution-induced pulmonary disease
-
Akopian, A.N., Fanick, E.R., Brooks, E.G., TRP channels and traffic-related environmental pollution-induced pulmonary disease. Semin. Immunopathol. 38 (2016), 331–338.
-
(2016)
Semin. Immunopathol.
, vol.38
, pp. 331-338
-
-
Akopian, A.N.1
Fanick, E.R.2
Brooks, E.G.3
-
165
-
-
1242329293
-
TRPV1 receptors mediate particulate matter-induced apoptosis: american journal of physiology
-
Agopyan, N., Head, J., Yu, S., Simon, S.A., TRPV1 receptors mediate particulate matter-induced apoptosis: american journal of physiology. Lung Cell. Mol. Physiol. 286 (2004), L563–572.
-
(2004)
Lung Cell. Mol. Physiol.
, vol.286
, pp. L563-572
-
-
Agopyan, N.1
Head, J.2
Yu, S.3
Simon, S.A.4
-
166
-
-
0141783754
-
Vanilloid receptor activation by 2- and 10-microm particles induces responses leading to apoptosis in human airway epithelial cells
-
Agopyan, N., Bhatti, T., Yu, S., Simon, S.A., Vanilloid receptor activation by 2- and 10-microm particles induces responses leading to apoptosis in human airway epithelial cells. Toxicol. Appl. Pharmacol. 192 (2003), 21–35.
-
(2003)
Toxicol. Appl. Pharmacol.
, vol.192
, pp. 21-35
-
-
Agopyan, N.1
Bhatti, T.2
Yu, S.3
Simon, S.A.4
-
167
-
-
0034669190
-
Vanilloid (capsaicin) receptors influence inflammatory sensitivity in response to particulate matter
-
Veronesi, B., Oortgiesen, M., Roy, J., Carter, J.D., Simon, S.A., Gavett, S.H., Vanilloid (capsaicin) receptors influence inflammatory sensitivity in response to particulate matter. Toxicol. Appl. Pharmacol. 169 (2000), 66–76.
-
(2000)
Toxicol. Appl. Pharmacol.
, vol.169
, pp. 66-76
-
-
Veronesi, B.1
Oortgiesen, M.2
Roy, J.3
Carter, J.D.4
Simon, S.A.5
Gavett, S.H.6
-
168
-
-
35848940292
-
Alpha, beta-unsaturated aldehydes in cigarette smoke release inflammatory mediators from human macrophages
-
Facchinetti, F., Amadei, F., Geppetti, P., Tarantini, F., Di Serio, C., Dragotto, A., Gigli, P.M., Catinella, S., Civelli, M., Patacchini, R., Alpha, beta-unsaturated aldehydes in cigarette smoke release inflammatory mediators from human macrophages. Am. J. Respir. Cell Mol. Biol. 37 (2007), 617–623.
-
(2007)
Am. J. Respir. Cell Mol. Biol.
, vol.37
, pp. 617-623
-
-
Facchinetti, F.1
Amadei, F.2
Geppetti, P.3
Tarantini, F.4
Di Serio, C.5
Dragotto, A.6
Gigli, P.M.7
Catinella, S.8
Civelli, M.9
Patacchini, R.10
-
169
-
-
77951957689
-
Activations of TRPA1 and P2X receptors are important in ROS-mediated stimulation of capsaicin-sensitive lung vagal afferents by cigarette smoke in rats
-
Lin, Y.S., Hsu, C.C., Bien, M.Y., Hsu, H.C., Weng, H.T., Kou, Y.R., Activations of TRPA1 and P2X receptors are important in ROS-mediated stimulation of capsaicin-sensitive lung vagal afferents by cigarette smoke in rats. J. Appl. Physiol. (1985) 108 (2010), 1293–1303.
-
(2010)
J. Appl. Physiol. (1985)
, vol.108
, pp. 1293-1303
-
-
Lin, Y.S.1
Hsu, C.C.2
Bien, M.Y.3
Hsu, H.C.4
Weng, H.T.5
Kou, Y.R.6
-
170
-
-
70349559585
-
Nicotine activates the chemosensory cation channel TRPA1
-
Talavera, K., Gees, M., Karashima, Y., Meseguer, V.M., Vanoirbeek, J.A., Damann, N., Everaerts, W., Benoit, M., Janssens, A., Vennekens, R., Viana, F., Nemery, B., Nilius, B., Voets, T., Nicotine activates the chemosensory cation channel TRPA1. Nat. Neurosci. 12 (2009), 1293–1299.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 1293-1299
-
-
Talavera, K.1
Gees, M.2
Karashima, Y.3
Meseguer, V.M.4
Vanoirbeek, J.A.5
Damann, N.6
Everaerts, W.7
Benoit, M.8
Janssens, A.9
Vennekens, R.10
Viana, F.11
Nemery, B.12
Nilius, B.13
Voets, T.14
-
171
-
-
46749091281
-
Cigarette smoke-induced neurogenic inflammation is mediated by alpha, beta-unsaturated aldehydes and the TRPA1 receptor in rodents
-
Andre, E., Campi, B., Materazzi, S., Trevisani, M., Amadesi, S., Massi, D., Creminon, C., Vaksman, N., Nassini, R., Civelli, M., Baraldi, P.G., Poole, D.P., Bunnett, N.W., Geppetti, P., Patacchini, R., Cigarette smoke-induced neurogenic inflammation is mediated by alpha, beta-unsaturated aldehydes and the TRPA1 receptor in rodents. J. Clin. Invest. 118 (2008), 2574–2582.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2574-2582
-
-
Andre, E.1
Campi, B.2
Materazzi, S.3
Trevisani, M.4
Amadesi, S.5
Massi, D.6
Creminon, C.7
Vaksman, N.8
Nassini, R.9
Civelli, M.10
Baraldi, P.G.11
Poole, D.P.12
Bunnett, N.W.13
Geppetti, P.14
Patacchini, R.15
-
172
-
-
65549109223
-
Association of TRPV4 gene polymorphisms with chronic obstructive pulmonary disease
-
Zhu, G., Gulsvik, A., Bakke, P., Ghatta, S., Anderson, W., Lomas, D.A., Silverman, E.K., Pillai, S.G., Association of TRPV4 gene polymorphisms with chronic obstructive pulmonary disease. Hum. Mol. Genet. 18 (2009), 2053–2062.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 2053-2062
-
-
Zhu, G.1
Gulsvik, A.2
Bakke, P.3
Ghatta, S.4
Anderson, W.5
Lomas, D.A.6
Silverman, E.K.7
Pillai, S.G.8
-
173
-
-
67049119907
-
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
-
Caceres, A.I., Brackmann, M., Elia, M.D., Bessac, B.F., del Camino, D., D'Amours, M., Witek, J.S., Fanger, C.M., Chong, J.A., Hayward, N.J., Homer, R.J., Cohn, L., Huang, X., Moran, M.M., Jordt, S.E., A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 9099–9104.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 9099-9104
-
-
Caceres, A.I.1
Brackmann, M.2
Elia, M.D.3
Bessac, B.F.4
del Camino, D.5
D'Amours, M.6
Witek, J.S.7
Fanger, C.M.8
Chong, J.A.9
Hayward, N.J.10
Homer, R.J.11
Cohn, L.12
Huang, X.13
Moran, M.M.14
Jordt, S.E.15
-
174
-
-
84855204361
-
A role for sensory nerves in the late asthmatic response
-
Raemdonck, K., de Alba, J., Birrell, M.A., Grace, M., Maher, S.A., Irvin, C.G., Fozard, J.R., O'Byrne, P.M., Belvisi, M.G., A role for sensory nerves in the late asthmatic response. Thorax 67 (2012), 19–25.
-
(2012)
Thorax
, vol.67
, pp. 19-25
-
-
Raemdonck, K.1
de Alba, J.2
Birrell, M.A.3
Grace, M.4
Maher, S.A.5
Irvin, C.G.6
Fozard, J.R.7
O'Byrne, P.M.8
Belvisi, M.G.9
-
175
-
-
84875151356
-
Crucial role of transient receptor potential ankyrin 1 and mast cells in induction of nonallergic airway hyperreactivity in mice
-
Hox, V., Vanoirbeek, J.A., Alpizar, Y.A., Voedisch, S., Callebaut, I., Bobic, S., Sharify, A., De Vooght, V., Van Gerven, L., Devos, F., Liston, A., Voets, T., Vennekens, R., Bullens, D.M., De Vries, A., Hoet, P., Braun, A., Ceuppens, J.L., Talavera, K., Nemery, B., Hellings, P.W., Crucial role of transient receptor potential ankyrin 1 and mast cells in induction of nonallergic airway hyperreactivity in mice. Am. J. Respir. Crit. Care Med. 187 (2013), 486–493.
-
(2013)
Am. J. Respir. Crit. Care Med.
, vol.187
, pp. 486-493
-
-
Hox, V.1
Vanoirbeek, J.A.2
Alpizar, Y.A.3
Voedisch, S.4
Callebaut, I.5
Bobic, S.6
Sharify, A.7
De Vooght, V.8
Van Gerven, L.9
Devos, F.10
Liston, A.11
Voets, T.12
Vennekens, R.13
Bullens, D.M.14
De Vries, A.15
Hoet, P.16
Braun, A.17
Ceuppens, J.L.18
Talavera, K.19
Nemery, B.20
Hellings, P.W.21
more..
-
176
-
-
50249160065
-
Loss of classical transient receptor potential 6 channel reduces allergic airway response
-
Sel, S., Rost, B.R., Yildirim, A.O., Sel, B., Kalwa, H., Fehrenbach, H., Renz, H., Gudermann, T., Dietrich, A., Loss of classical transient receptor potential 6 channel reduces allergic airway response. Clin. Exp. Allergy 38 (2008), 1548–1558.
-
(2008)
Clin. Exp. Allergy
, vol.38
, pp. 1548-1558
-
-
Sel, S.1
Rost, B.R.2
Yildirim, A.O.3
Sel, B.4
Kalwa, H.5
Fehrenbach, H.6
Renz, H.7
Gudermann, T.8
Dietrich, A.9
-
177
-
-
84974817778
-
Canonical transient receptor potential 3 channels activate NF-kappaB to mediate allergic airway disease via PKC-alpha/IkappaB-alpha and calcineurin/IkappaB-beta pathways
-
Song, T., Zheng, Y.M., Vincent, P.A., Cai, D., Rosenberg, P., Wang, Y.X., Canonical transient receptor potential 3 channels activate NF-kappaB to mediate allergic airway disease via PKC-alpha/IkappaB-alpha and calcineurin/IkappaB-beta pathways. FASEB J. 30 (2016), 214–229.
-
(2016)
FASEB J.
, vol.30
, pp. 214-229
-
-
Song, T.1
Zheng, Y.M.2
Vincent, P.A.3
Cai, D.4
Rosenberg, P.5
Wang, Y.X.6
-
178
-
-
85011044750
-
Inhibition of TRPC3 downregulates airway hyperresponsiveness, remodeling of OVA-sensitized mouse
-
Wang, L., Li, J., Zhang, J., He, Q., Weng, X., Huang, Y., Guan, M., Qiu, C., Inhibition of TRPC3 downregulates airway hyperresponsiveness, remodeling of OVA-sensitized mouse. Biochem. Biophys. Res. Commun. 484 (2017), 209–217.
-
(2017)
Biochem. Biophys. Res. Commun.
, vol.484
, pp. 209-217
-
-
Wang, L.1
Li, J.2
Zhang, J.3
He, Q.4
Weng, X.5
Huang, Y.6
Guan, M.7
Qiu, C.8
-
179
-
-
79957624012
-
C-fibers but not the transient potential receptor vanilloid 1 (TRPV1), play a role in experimental allergic airway inflammation
-
Rogerio, A.P., Andrade, E.L., Calixto, J.B., C-fibers but not the transient potential receptor vanilloid 1 (TRPV1), play a role in experimental allergic airway inflammation. Eur. J. Pharmacol. 662 (2011), 55–62.
-
(2011)
Eur. J. Pharmacol.
, vol.662
, pp. 55-62
-
-
Rogerio, A.P.1
Andrade, E.L.2
Calixto, J.B.3
-
180
-
-
84862285513
-
Inhibition of airway hyper-responsiveness by TRPV1 antagonists (SB-705498 and PF-04065463) in the unanaesthetized, ovalbumin-sensitized guinea pig
-
Delescluse, I., Mace, H., Adcock, J.J., Inhibition of airway hyper-responsiveness by TRPV1 antagonists (SB-705498 and PF-04065463) in the unanaesthetized, ovalbumin-sensitized guinea pig. Br. J. Pharmacol. 166 (2012), 1822–1832.
-
(2012)
Br. J. Pharmacol.
, vol.166
, pp. 1822-1832
-
-
Delescluse, I.1
Mace, H.2
Adcock, J.J.3
-
181
-
-
77956235414
-
Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma
-
Cantero-Recasens, G., Gonzalez, J.R., Fandos, C., Duran-Tauleria, E., Smit, L.A., Kauffmann, F., Anto, J.M., Valverde, M.A., Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma. J. Biol. Chem. 285 (2010), 27532–27535.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 27532-27535
-
-
Cantero-Recasens, G.1
Gonzalez, J.R.2
Fandos, C.3
Duran-Tauleria, E.4
Smit, L.A.5
Kauffmann, F.6
Anto, J.M.7
Valverde, M.A.8
-
182
-
-
84860519073
-
TRPV1 induction in airway vagal low-threshold mechanosensory neurons by allergen challenge and neurotrophic factors, American journal of physiology
-
Lieu, T.M., Myers, A.C., Meeker, S., Undem, B.J., TRPV1 induction in airway vagal low-threshold mechanosensory neurons by allergen challenge and neurotrophic factors, American journal of physiology. Lung Cell. Mol. Physiol. 302 (2012), L941–948.
-
(2012)
Lung Cell. Mol. Physiol.
, vol.302
, pp. L941-948
-
-
Lieu, T.M.1
Myers, A.C.2
Meeker, S.3
Undem, B.J.4
-
183
-
-
85017302219
-
Mechanosensitive transient receptor potential vanilloid 4 regulates Dermatophagoides farinae-induced airway remodeling via 2 distinct pathways modulating matrix synthesis and degradation
-
Gombedza, F., Kondeti, V., Al-Azzam, N., Koppes, S., Duah, E., Patil, P., Hexter, M., Phillips, D., Thodeti, C.K., Paruchuri, S., Mechanosensitive transient receptor potential vanilloid 4 regulates Dermatophagoides farinae-induced airway remodeling via 2 distinct pathways modulating matrix synthesis and degradation. FASEB J. 31 (2017), 1556–1570.
-
(2017)
FASEB J.
, vol.31
, pp. 1556-1570
-
-
Gombedza, F.1
Kondeti, V.2
Al-Azzam, N.3
Koppes, S.4
Duah, E.5
Patil, P.6
Hexter, M.7
Phillips, D.8
Thodeti, C.K.9
Paruchuri, S.10
-
184
-
-
84945448175
-
Transient receptor potential melastatin 8 gene polymorphism is associated with cold-induced airway hyperresponsiveness in bronchial asthma
-
Naumov, D.E., Perelman, J.M., Kolosov, V.P., Potapova, T.A., Maksimov, V.N., Zhou, X., Transient receptor potential melastatin 8 gene polymorphism is associated with cold-induced airway hyperresponsiveness in bronchial asthma. Respirology 20 (2015), 1192–1197.
-
(2015)
Respirology
, vol.20
, pp. 1192-1197
-
-
Naumov, D.E.1
Perelman, J.M.2
Kolosov, V.P.3
Potapova, T.A.4
Maksimov, V.N.5
Zhou, X.6
-
185
-
-
80052267978
-
Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism
-
(e621-625)
-
Li, M., Li, Q., Yang, G., Kolosov, V.P., Perelman, J.M., Zhou, X.D., Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism. J. Allergy Clin. Immunol. 128 (2011), 626–634 (e621-625).
-
(2011)
J. Allergy Clin. Immunol.
, vol.128
, pp. 626-634
-
-
Li, M.1
Li, Q.2
Yang, G.3
Kolosov, V.P.4
Perelman, J.M.5
Zhou, X.D.6
-
186
-
-
84894261996
-
The rise of oxygen in Earth's early ocean and atmosphere
-
Lyons, T.W., Reinhard, C.T., Planavsky, N.J., The rise of oxygen in Earth's early ocean and atmosphere. Nature 506 (2014), 307–315.
-
(2014)
Nature
, vol.506
, pp. 307-315
-
-
Lyons, T.W.1
Reinhard, C.T.2
Planavsky, N.J.3
-
187
-
-
84923164260
-
Peripheral neural circuitry in cough
-
Taylor-Clark, T.E., Peripheral neural circuitry in cough. Curr. Opin. Pharmacol. 22 (2015), 9–17.
-
(2015)
Curr. Opin. Pharmacol.
, vol.22
, pp. 9-17
-
-
Taylor-Clark, T.E.1
-
188
-
-
84987990585
-
Mechanisms of the acute effects of inhaled ozone in humans
-
Bromberg, P.A., Mechanisms of the acute effects of inhaled ozone in humans. Biochim. Biophys. Acta 1860 (2016), 2771–2781.
-
(2016)
Biochim. Biophys. Acta
, vol.1860
, pp. 2771-2781
-
-
Bromberg, P.A.1
-
189
-
-
79953156425
-
Irritating channels: the case of TRPA1
-
Nilius, B., Prenen, J., Owsianik, G., Irritating channels: the case of TRPA1. J. Physiol. 589 (2011), 1543–1549.
-
(2011)
J. Physiol.
, vol.589
, pp. 1543-1549
-
-
Nilius, B.1
Prenen, J.2
Owsianik, G.3
-
190
-
-
35348873821
-
TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs, American journal of physiology
-
Hamanaka, K., Jian, M.Y., Weber, D.S., Alvarez, D.F., Townsley, M.I., Al-Mehdi, A.B., King, J.A., Liedtke, W., Parker, J.C., TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs, American journal of physiology. Lung cellular and molecular physiology 293 (2007), L923–932.
-
(2007)
Lung cellular and molecular physiology
, vol.293
, pp. L923-932
-
-
Hamanaka, K.1
Jian, M.Y.2
Weber, D.S.3
Alvarez, D.F.4
Townsley, M.I.5
Al-Mehdi, A.B.6
King, J.A.7
Liedtke, W.8
Parker, J.C.9
-
191
-
-
84995745225
-
Transient receptor potential vanilloid 4 and serum glucocorticoid-regulated kinase 1 are critical mediators of lung injury in overventilated mice In vivo
-
Michalick, L., Erfinanda, L., Weichelt, U., van der Giet, M., Liedtke, W., Kuebler, W.M., Transient receptor potential vanilloid 4 and serum glucocorticoid-regulated kinase 1 are critical mediators of lung injury in overventilated mice In vivo. Anesthesiology 126 (2017), 300–311.
-
(2017)
Anesthesiology
, vol.126
, pp. 300-311
-
-
Michalick, L.1
Erfinanda, L.2
Weichelt, U.3
van der Giet, M.4
Liedtke, W.5
Kuebler, W.M.6
-
192
-
-
84925481981
-
TRPV4: physiological role and therapeutic potential in respiratory diseases
-
Goldenberg, N.M., Ravindran, K., Kuebler, W.M., TRPV4: physiological role and therapeutic potential in respiratory diseases. Naunyn. Schmiedebergs Arch. Pharmacol. 388 (2015), 421–436.
-
(2015)
Naunyn. Schmiedebergs Arch. Pharmacol.
, vol.388
, pp. 421-436
-
-
Goldenberg, N.M.1
Ravindran, K.2
Kuebler, W.M.3
-
193
-
-
84915748921
-
TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice
-
Rahaman, S.O., Grove, L.M., Paruchuri, S., Southern, B.D., Abraham, S., Niese, K.A., Scheraga, R.G., Ghosh, S., Thodeti, C.K., Zhang, D.X., Moran, M.M., Schilling, W.P., Tschumperlin, D.J., Olman, M.A., TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice. J. Clin. Invest. 124 (2014), 5225–5238.
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 5225-5238
-
-
Rahaman, S.O.1
Grove, L.M.2
Paruchuri, S.3
Southern, B.D.4
Abraham, S.5
Niese, K.A.6
Scheraga, R.G.7
Ghosh, S.8
Thodeti, C.K.9
Zhang, D.X.10
Moran, M.M.11
Schilling, W.P.12
Tschumperlin, D.J.13
Olman, M.A.14
-
194
-
-
85003811129
-
Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis
-
Hofmann, K., Fiedler, S., Vierkotten, S., Weber, J., Klee, S., Jia, J., Zwickenpflug, W., Flockerzi, V., Storch, U., Yildirim, A.O., Gudermann, T., Konigshoff, M., Dietrich, A., Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis. Biochim. Biophys. Acta 1863 (2017), 560–568.
-
(2017)
Biochim. Biophys. Acta
, vol.1863
, pp. 560-568
-
-
Hofmann, K.1
Fiedler, S.2
Vierkotten, S.3
Weber, J.4
Klee, S.5
Jia, J.6
Zwickenpflug, W.7
Flockerzi, V.8
Storch, U.9
Yildirim, A.O.10
Gudermann, T.11
Konigshoff, M.12
Dietrich, A.13
-
195
-
-
84867732495
-
A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo
-
Davis, J., Burr, A.R., Davis, G.F., Birnbaumer, L., Molkentin, J.D., A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Dev. Cell 23 (2012), 705–715.
-
(2012)
Dev. Cell
, vol.23
, pp. 705-715
-
-
Davis, J.1
Burr, A.R.2
Davis, G.F.3
Birnbaumer, L.4
Molkentin, J.D.5
-
196
-
-
20244375821
-
Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice
-
Freichel, M., Suh, S.H., Pfeifer, A., Schweig, U., Trost, C., Weissgerber, P., Biel, M., Philipp, S., Freise, D., Droogmans, G., Hofmann, F., Flockerzi, V., Nilius, B., Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice. Nat. Cell Biol. 3 (2001), 121–127.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 121-127
-
-
Freichel, M.1
Suh, S.H.2
Pfeifer, A.3
Schweig, U.4
Trost, C.5
Weissgerber, P.6
Biel, M.7
Philipp, S.8
Freise, D.9
Droogmans, G.10
Hofmann, F.11
Flockerzi, V.12
Nilius, B.13
-
197
-
-
0037067430
-
Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability
-
Tiruppathi, C., Freichel, M., Vogel, S.M., Paria, B.C., Mehta, D., Flockerzi, V., Malik, A.B., Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability. Circ. Res. 91 (2002), 70–76.
-
(2002)
Circ. Res.
, vol.91
, pp. 70-76
-
-
Tiruppathi, C.1
Freichel, M.2
Vogel, S.M.3
Paria, B.C.4
Mehta, D.5
Flockerzi, V.6
Malik, A.B.7
-
198
-
-
84858788478
-
The Ca(2 +) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2 +) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells
-
Sundivakkam, P.C., Freichel, M., Singh, V., Yuan, J.P., Vogel, S.M., Flockerzi, V., Malik, A.B., Tiruppathi, C., The Ca(2 +) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2 +) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells. Mol. Pharmacol. 81 (2012), 510–526.
-
(2012)
Mol. Pharmacol.
, vol.81
, pp. 510-526
-
-
Sundivakkam, P.C.1
Freichel, M.2
Singh, V.3
Yuan, J.P.4
Vogel, S.M.5
Flockerzi, V.6
Malik, A.B.7
Tiruppathi, C.8
-
199
-
-
84875716476
-
STIMulating stress fibers in endothelial cells
-
Gudermann, T., Steinritz, D., STIMulating stress fibers in endothelial cells. Sci. Signal., 6, 2013, pe8.
-
(2013)
Sci. Signal.
, vol.6
, pp. pe8
-
-
Gudermann, T.1
Steinritz, D.2
-
200
-
-
84875755342
-
STIM1 controls endothelial barrier function independently of Orai1 and Ca2+ entry
-
Shinde, A.V., Motiani, R.K., Zhang, X., Abdullaev, I.F., Adam, A.P., Gonzalez-Cobos, J.C., Zhang, W., Matrougui, K., Vincent, P.A., Trebak, M., STIM1 controls endothelial barrier function independently of Orai1 and Ca2+ entry. Sci. Signal., 6, 2013, ra18.
-
(2013)
Sci. Signal.
, vol.6
, pp. ra18
-
-
Shinde, A.V.1
Motiani, R.K.2
Zhang, X.3
Abdullaev, I.F.4
Adam, A.P.5
Gonzalez-Cobos, J.C.6
Zhang, W.7
Matrougui, K.8
Vincent, P.A.9
Trebak, M.10
-
201
-
-
84860255381
-
Models and mechanisms of acute lung injury caused by direct insults
-
Reiss, L.K., Uhlig, U., Uhlig, S., Models and mechanisms of acute lung injury caused by direct insults. Eur. J. Cell Biol. 91 (2012), 590–601.
-
(2012)
Eur. J. Cell Biol.
, vol.91
, pp. 590-601
-
-
Reiss, L.K.1
Uhlig, U.2
Uhlig, S.3
-
202
-
-
0026767075
-
Platelet-activating factor in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome
-
Matsumoto, K., Taki, F., Kondoh, Y., Taniguchi, H., Takagi, K., Platelet-activating factor in bronchoalveolar lavage fluid of patients with adult respiratory distress syndrome. Clin. Exp. Pharmacol. Physiol. 19 (1992), 509–515.
-
(1992)
Clin. Exp. Pharmacol. Physiol.
, vol.19
, pp. 509-515
-
-
Matsumoto, K.1
Taki, F.2
Kondoh, Y.3
Taniguchi, H.4
Takagi, K.5
-
203
-
-
0030901314
-
Proteins and phospholipids in BAL from patients with hydrostatic pulmonary edema
-
Nakos, J., Pneumatikos, I., Tsangaris, C., Tellis, M., Proteins and phospholipids in BAL from patients with hydrostatic pulmonary edema. Am. J. Respir. Crit. Care Med. 155 (1997), 945–951.
-
(1997)
Am. J. Respir. Crit. Care Med.
, vol.155
, pp. 945-951
-
-
Nakos, J.1
Pneumatikos, I.2
Tsangaris, C.3
Tellis, M.4
-
204
-
-
33645696641
-
Mechanisms of platelet-activating factor (PAF)-mediated responses in the lung
-
(Suppl)
-
Uhlig, R., Goggel, S., Mechanisms of platelet-activating factor (PAF)-mediated responses in the lung. Pharmacological reports: PR 57 (2005), 206–221 (Suppl).
-
(2005)
Pharmacological reports: PR
, vol.57
, pp. 206-221
-
-
Uhlig, R.1
Goggel, S.2
-
205
-
-
0036724432
-
Platelet-activating factor-induced pulmonary edema is partly mediated by prostaglandin E(2), E-prostanoid 3-receptors, and potassium channels
-
Goggel, R., Hoffman, S., Nusing, R., Narumiya, S., Uhlig, S., Platelet-activating factor-induced pulmonary edema is partly mediated by prostaglandin E(2), E-prostanoid 3-receptors, and potassium channels. Am. J. Respir. Crit. Care Med. 166 (2002), 657–662.
-
(2002)
Am. J. Respir. Crit. Care Med.
, vol.166
, pp. 657-662
-
-
Goggel, R.1
Hoffman, S.2
Nusing, R.3
Narumiya, S.4
Uhlig, S.5
-
206
-
-
11144354259
-
PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide
-
Goggel, R., Winoto-Morbach, S., Vielhaber, G., Imai, Y., Lindner, K., Brade, L., Brade, H., Ehlers, S., Slutsky, A.S., Schutze, S., Gulbins, E., Uhlig, S., PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide. Nat. Med. 10 (2004), 155–160.
-
(2004)
Nat. Med.
, vol.10
, pp. 155-160
-
-
Goggel, R.1
Winoto-Morbach, S.2
Vielhaber, G.3
Imai, Y.4
Lindner, K.5
Brade, L.6
Brade, H.7
Ehlers, S.8
Slutsky, A.S.9
Schutze, S.10
Gulbins, E.11
Uhlig, S.12
-
207
-
-
84856019712
-
Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6
-
Samapati, R., Yang, Y., Yin, J., Stoerger, C., Arenz, C., Dietrich, A., Gudermann, T., Adam, D., Wu, S., Freichel, M., Flockerzi, V., Uhlig, S., Kuebler, W.M., Lung endothelial Ca2+ and permeability response to platelet-activating factor is mediated by acid sphingomyelinase and transient receptor potential classical 6. Am. J. Respir. Crit. Care Med. 185 (2012), 160–170.
-
(2012)
Am. J. Respir. Crit. Care Med.
, vol.185
, pp. 160-170
-
-
Samapati, R.1
Yang, Y.2
Yin, J.3
Stoerger, C.4
Arenz, C.5
Dietrich, A.6
Gudermann, T.7
Adam, D.8
Wu, S.9
Freichel, M.10
Flockerzi, V.11
Uhlig, S.12
Kuebler, W.M.13
-
208
-
-
84870256592
-
TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation
-
Tauseef, M., Knezevic, N., Chava, K.R., Smith, M., Sukriti, S., Gianaris, N., Obukhov, A.G., Vogel, S.M., Schraufnagel, D.E., Dietrich, A., Birnbaumer, L., Malik, A.B., Mehta, D., TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation. J. Exp. Med. 209 (2012), 1953–1968.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1953-1968
-
-
Tauseef, M.1
Knezevic, N.2
Chava, K.R.3
Smith, M.4
Sukriti, S.5
Gianaris, N.6
Obukhov, A.G.7
Vogel, S.M.8
Schraufnagel, D.E.9
Dietrich, A.10
Birnbaumer, L.11
Malik, A.B.12
Mehta, D.13
-
209
-
-
84856692677
-
Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice
-
Weissmann, N., Sydykov, A., Kalwa, H., Storch, U., Fuchs, B., Mederos y Schnitzler, M., Brandes, R.P., Grimminger, F., Meissner, M., Freichel, M., Offermanns, S., Veit, F., Pak, O., Krause, K.H., Schermuly, R.T., Brewer, A.C., Schmidt, H.H., Seeger, W., Shah, A.M., Gudermann, T., Ghofrani, H.A., Dietrich, A., Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice. Nat. Commun., 3, 2012, 649.
-
(2012)
Nat. Commun.
, vol.3
, pp. 649
-
-
Weissmann, N.1
Sydykov, A.2
Kalwa, H.3
Storch, U.4
Fuchs, B.5
Mederos y Schnitzler, M.6
Brandes, R.P.7
Grimminger, F.8
Meissner, M.9
Freichel, M.10
Offermanns, S.11
Veit, F.12
Pak, O.13
Krause, K.H.14
Schermuly, R.T.15
Brewer, A.C.16
Schmidt, H.H.17
Seeger, W.18
Shah, A.M.19
Gudermann, T.20
Ghofrani, H.A.21
Dietrich, A.22
more..
-
210
-
-
84864360259
-
The NOX toolbox: validating the role of NADPH oxidases in physiology and disease
-
Altenhofer, S., Kleikers, P.W., Radermacher, K.A., Scheurer, P., Rob Hermans, J.J., Schiffers, P., Ho, H., Wingler, K., Schmidt, H.H., The NOX toolbox: validating the role of NADPH oxidases in physiology and disease. Cell. Mol. Life Sci.: CMLS 69 (2012), 2327–2343.
-
(2012)
Cell. Mol. Life Sci.: CMLS
, vol.69
, pp. 2327-2343
-
-
Altenhofer, S.1
Kleikers, P.W.2
Radermacher, K.A.3
Scheurer, P.4
Rob Hermans, J.J.5
Schiffers, P.6
Ho, H.7
Wingler, K.8
Schmidt, H.H.9
-
211
-
-
84861062943
-
Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
-
Lassegue, B., San Martin, A., Griendling, K.K., Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system. Circ. Res. 110 (2012), 1364–1390.
-
(2012)
Circ. Res.
, vol.110
, pp. 1364-1390
-
-
Lassegue, B.1
San Martin, A.2
Griendling, K.K.3
-
212
-
-
84864356954
-
Targeting NOX enzymes in pulmonary fibrosis
-
Hecker, L., Cheng, J., Thannickal, V.J., Targeting NOX enzymes in pulmonary fibrosis. Cell. Mol. Life Sci.: CMLS 69 (2012), 2365–2371.
-
(2012)
Cell. Mol. Life Sci.: CMLS
, vol.69
, pp. 2365-2371
-
-
Hecker, L.1
Cheng, J.2
Thannickal, V.J.3
-
213
-
-
84864375987
-
siRNA-mediated knock-down of NOX3: therapy for hearing loss?
-
Rybak, L.P., Mukherjea, D., Jajoo, S., Kaur, T., Ramkumar, V., siRNA-mediated knock-down of NOX3: therapy for hearing loss?. Cell. Mol. Life Sci.: CMLS 69 (2012), 2429–2434.
-
(2012)
Cell. Mol. Life Sci.: CMLS
, vol.69
, pp. 2429-2434
-
-
Rybak, L.P.1
Mukherjea, D.2
Jajoo, S.3
Kaur, T.4
Ramkumar, V.5
-
214
-
-
79957518453
-
A key role for NOX4 in epithelial cell death during development of lung fibrosis
-
Carnesecchi, S., Deffert, C., Donati, Y., Basset, O., Hinz, B., Preynat-Seauve, O., Guichard, C., Arbiser, J.L., Banfi, B., Pache, J.C., Barazzone-Argiroffo, C., Krause, K.H., A key role for NOX4 in epithelial cell death during development of lung fibrosis. Antioxidants Redox Signal. 15 (2011), 607–619.
-
(2011)
Antioxidants Redox Signal.
, vol.15
, pp. 607-619
-
-
Carnesecchi, S.1
Deffert, C.2
Donati, Y.3
Basset, O.4
Hinz, B.5
Preynat-Seauve, O.6
Guichard, C.7
Arbiser, J.L.8
Banfi, B.9
Pache, J.C.10
Barazzone-Argiroffo, C.11
Krause, K.H.12
-
215
-
-
68949200471
-
The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death
-
Cristovao, A.C., Choi, D.H., Baltazar, G., Beal, M.F., Kim, Y.S., The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death. Antioxidants Redox Signal. 11 (2009), 2105–2118.
-
(2009)
Antioxidants Redox Signal.
, vol.11
, pp. 2105-2118
-
-
Cristovao, A.C.1
Choi, D.H.2
Baltazar, G.3
Beal, M.F.4
Kim, Y.S.5
-
216
-
-
0031885884
-
Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer
-
Bokemeyer, C., Berger, C.C., Hartmann, J.T., Kollmannsberger, C., Schmoll, H.J., Kuczyk, M.A., Kanz, L., Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer. Br. J. Cancer 77 (1998), 1355–1362.
-
(1998)
Br. J. Cancer
, vol.77
, pp. 1355-1362
-
-
Bokemeyer, C.1
Berger, C.C.2
Hartmann, J.T.3
Kollmannsberger, C.4
Schmoll, H.J.5
Kuczyk, M.A.6
Kanz, L.7
-
217
-
-
0021288059
-
Paraquat: model for oxidant-initiated toxicity
-
Bus, J.S., Gibson, J.E., Paraquat: model for oxidant-initiated toxicity. Environ. Health Perspect. 55 (1984), 37–46.
-
(1984)
Environ. Health Perspect.
, vol.55
, pp. 37-46
-
-
Bus, J.S.1
Gibson, J.E.2
-
218
-
-
24944517043
-
Damage and threshold shift resulting from cochlear exposure to paraquat-generated superoxide
-
Bielefeld, E.C., Hu, B.H., Harris, K.C., Henderson, D., Damage and threshold shift resulting from cochlear exposure to paraquat-generated superoxide. Hear. Res. 207 (2005), 35–42.
-
(2005)
Hear. Res.
, vol.207
, pp. 35-42
-
-
Bielefeld, E.C.1
Hu, B.H.2
Harris, K.C.3
Henderson, D.4
-
219
-
-
84867588505
-
NADPH oxidase 1 mediates alpha-synucleinopathy in parkinson's disease
-
Cristovao, A.C., Guhathakurta, S., Bok, E., Je, G., Yoo, S.D., Choi, D.H., Kim, Y.S., NADPH oxidase 1 mediates alpha-synucleinopathy in parkinson's disease. J. Neurosci. 32 (2012), 14465–14477.
-
(2012)
J. Neurosci.
, vol.32
, pp. 14465-14477
-
-
Cristovao, A.C.1
Guhathakurta, S.2
Bok, E.3
Je, G.4
Yoo, S.D.5
Choi, D.H.6
Kim, Y.S.7
-
220
-
-
84864403641
-
Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases
-
Lee, I.T., Yang, C.M., Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases. Biochem. Pharmacol. 84 (2012), 581–590.
-
(2012)
Biochem. Pharmacol.
, vol.84
, pp. 581-590
-
-
Lee, I.T.1
Yang, C.M.2
-
221
-
-
48649095693
-
Role of TRPM2 channel in mediating H2O2-Induced Ca2+ entry and endothelial hyperpermeability
-
Hecquet, C.M., Ahmmed, G.U., Vogel, S.M., Malik, A.B., Role of TRPM2 channel in mediating H2O2-Induced Ca2+ entry and endothelial hyperpermeability. Circ. Res., 2007.
-
(2007)
Circ. Res.
-
-
Hecquet, C.M.1
Ahmmed, G.U.2
Vogel, S.M.3
Malik, A.B.4
-
222
-
-
60749126088
-
TRPing on the lung endothelium: calcium channels that regulate barrier function
-
Cioffi, D.L., Lowe, K., Alvarez, D.F., Barry, C., Stevens, T., TRPing on the lung endothelium: calcium channels that regulate barrier function. Antioxidants Redox Signal. 11 (2009), 765–776.
-
(2009)
Antioxidants Redox Signal.
, vol.11
, pp. 765-776
-
-
Cioffi, D.L.1
Lowe, K.2
Alvarez, D.F.3
Barry, C.4
Stevens, T.5
-
223
-
-
84887571932
-
Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction, American journal of physiology
-
Herold, S., Gabrielli, N.M., Vadasz, I., Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction, American journal of physiology. Lung Cell. Mol. Physiol. 305 (2013), L665–681.
-
(2013)
Lung Cell. Mol. Physiol.
, vol.305
, pp. L665-681
-
-
Herold, S.1
Gabrielli, N.M.2
Vadasz, I.3
-
224
-
-
80655145896
-
Functional and molecular heterogeneity of pulmonary endothelial cells
-
Stevens, T., Functional and molecular heterogeneity of pulmonary endothelial cells. Proc. Am. Thorac. Soc. 8 (2011), 453–457.
-
(2011)
Proc. Am. Thorac. Soc.
, vol.8
, pp. 453-457
-
-
Stevens, T.1
-
225
-
-
70349773183
-
Ca2+ entry via alpha1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium, American journal of physiology
-
Wu, S., Jian, M.Y., Xu, Y.C., Zhou, C., Al-Mehdi, A.B., Liedtke, W., Shin, H.S., Townsley, M.I., Ca2+ entry via alpha1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium, American journal of physiology. Lung Cell. Mol. Physiol. 297 (2009), L650–657.
-
(2009)
Lung Cell. Mol. Physiol.
, vol.297
, pp. L650-657
-
-
Wu, S.1
Jian, M.Y.2
Xu, Y.C.3
Zhou, C.4
Al-Mehdi, A.B.5
Liedtke, W.6
Shin, H.S.7
Townsley, M.I.8
-
226
-
-
41449112586
-
High vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4
-
Jian, M.Y., King, J.A., Al-Mehdi, A.B., Liedtke, W., Townsley, M.I., High vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4. Am. J. Respir. Cell Mol. Biol. 38 (2008), 386–392.
-
(2008)
Am. J. Respir. Cell Mol. Biol.
, vol.38
, pp. 386-392
-
-
Jian, M.Y.1
King, J.A.2
Al-Mehdi, A.B.3
Liedtke, W.4
Townsley, M.I.5
-
227
-
-
42549098958
-
Negative-feedback loop attenuates hydrostatic lung edema via a cGMP-dependent regulation of transient receptor potential vanilloid 4
-
Yin, J., Hoffmann, J., Kaestle, S.M., Neye, N., Wang, L., Baeurle, J., Liedtke, W., Wu, S., Kuppe, H., Pries, A.R., Kuebler, W.M., Negative-feedback loop attenuates hydrostatic lung edema via a cGMP-dependent regulation of transient receptor potential vanilloid 4. Circ. Res. 102 (2008), 966–974.
-
(2008)
Circ. Res.
, vol.102
, pp. 966-974
-
-
Yin, J.1
Hoffmann, J.2
Kaestle, S.M.3
Neye, N.4
Wang, L.5
Baeurle, J.6
Liedtke, W.7
Wu, S.8
Kuppe, H.9
Pries, A.R.10
Kuebler, W.M.11
-
228
-
-
0036081102
-
Pressure-induced endothelial Ca(2 +) oscillations in lung capillaries, American journal of physiology
-
Kuebler, W.M., Ying, X., Bhattacharya, J., Pressure-induced endothelial Ca(2 +) oscillations in lung capillaries, American journal of physiology. Lung Cell. Mol. Physiol. 282 (2002), L917–923.
-
(2002)
Lung Cell. Mol. Physiol.
, vol.282
, pp. L917-923
-
-
Kuebler, W.M.1
Ying, X.2
Bhattacharya, J.3
-
229
-
-
0344741460
-
Stretch activates nitric oxide production in pulmonary vascular endothelial cells in situ
-
Kuebler, W.M., Uhlig, U., Goldmann, T., Schael, G., Kerem, A., Exner, K., Martin, C., Vollmer, E., Uhlig, S., Stretch activates nitric oxide production in pulmonary vascular endothelial cells in situ. Am. J. Respir. Crit. Care Med. 168 (2003), 1391–1398.
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.168
, pp. 1391-1398
-
-
Kuebler, W.M.1
Uhlig, U.2
Goldmann, T.3
Schael, G.4
Kerem, A.5
Exner, K.6
Martin, C.7
Vollmer, E.8
Uhlig, S.9
-
230
-
-
58149316656
-
Secretogranin III directs secretory vesicle biogenesis in mast cells in a manner dependent upon interaction with chromogranin A
-
Prasad, P., Yanagihara, A.A., Small-Howard, A.L., Turner, H., Stokes, A.J., Secretogranin III directs secretory vesicle biogenesis in mast cells in a manner dependent upon interaction with chromogranin A. J. Immunol. 181 (2008), 5024–5034.
-
(2008)
J. Immunol.
, vol.181
, pp. 5024-5034
-
-
Prasad, P.1
Yanagihara, A.A.2
Small-Howard, A.L.3
Turner, H.4
Stokes, A.J.5
-
231
-
-
77956646454
-
Expression of transient receptor potential C6 channels in human lung macrophages
-
Finney-Hayward, T.K., Popa, M.O., Bahra, P., Li, S., Poll, C.T., Gosling, M., Nicholson, A.G., Russell, R.E., Kon, O.M., Jarai, G., Westwick, J., Barnes, P.J., Donnelly, L.E., Expression of transient receptor potential C6 channels in human lung macrophages. Am. J. Respir. Cell Mol. Biol. 43 (2010), 296–304.
-
(2010)
Am. J. Respir. Cell Mol. Biol.
, vol.43
, pp. 296-304
-
-
Finney-Hayward, T.K.1
Popa, M.O.2
Bahra, P.3
Li, S.4
Poll, C.T.5
Gosling, M.6
Nicholson, A.G.7
Russell, R.E.8
Kon, O.M.9
Jarai, G.10
Westwick, J.11
Barnes, P.J.12
Donnelly, L.E.13
-
232
-
-
57449114954
-
The calcium-conducting ion channel transient receptor potential canonical 6 is involved in macrophage inflammatory protein-2-induced migration of mouse neutrophils
-
Damann, N., Owsianik, G., Li, S., Poll, C., Nilius, B., The calcium-conducting ion channel transient receptor potential canonical 6 is involved in macrophage inflammatory protein-2-induced migration of mouse neutrophils. Acta Physiol. (Oxf) 195 (2009), 3–11.
-
(2009)
Acta Physiol. (Oxf)
, vol.195
, pp. 3-11
-
-
Damann, N.1
Owsianik, G.2
Li, S.3
Poll, C.4
Nilius, B.5
-
233
-
-
84878046889
-
TRPC6 regulates CXCR2-Mediated chemotaxis of murine neutrophils
-
Lindemann, O., Umlauf, D., Frank, S., Schimmelpfennig, S., Bertrand, J., Pap, T., Hanley, P.J., Fabian, A., Dietrich, A., Schwab, A., TRPC6 regulates CXCR2-Mediated chemotaxis of murine neutrophils. J. Immunol. 190 (2013), 5496–5505.
-
(2013)
J. Immunol.
, vol.190
, pp. 5496-5505
-
-
Lindemann, O.1
Umlauf, D.2
Frank, S.3
Schimmelpfennig, S.4
Bertrand, J.5
Pap, T.6
Hanley, P.J.7
Fabian, A.8
Dietrich, A.9
Schwab, A.10
-
234
-
-
84938494066
-
TRPM2 channel-mediated ROS-Sensitive Ca(2 + ) signaling mechanisms in immune cells
-
Syed Mortadza, S.A., Wang, L., Li, D., Jiang, L.H., TRPM2 channel-mediated ROS-Sensitive Ca(2 + ) signaling mechanisms in immune cells. Front. Immunol., 6, 2015, 407.
-
(2015)
Front. Immunol.
, vol.6
, pp. 407
-
-
Syed Mortadza, S.A.1
Wang, L.2
Li, D.3
Jiang, L.H.4
-
235
-
-
84858027505
-
TRPM2 contributes to inflammatory and neuropathic pain through the aggravation of pronociceptive inflammatory responses in mice
-
Haraguchi, K., Kawamoto, A., Isami, K., Maeda, S., Kusano, A., Asakura, K., Shirakawa, H., Mori, Y., Nakagawa, T., Kaneko, S., TRPM2 contributes to inflammatory and neuropathic pain through the aggravation of pronociceptive inflammatory responses in mice. J. Neurosci. 32 (2012), 3931–3941.
-
(2012)
J. Neurosci.
, vol.32
, pp. 3931-3941
-
-
Haraguchi, K.1
Kawamoto, A.2
Isami, K.3
Maeda, S.4
Kusano, A.5
Asakura, K.6
Shirakawa, H.7
Mori, Y.8
Nakagawa, T.9
Kaneko, S.10
-
236
-
-
46849091975
-
TRPM2-mediated Ca2 + influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
-
Yamamoto, S., Shimizu, S., Kiyonaka, S., Takahashi, N., Wajima, T., Hara, Y., Negoro, T., Hiroi, T., Kiuchi, Y., Okada, T., Kaneko, S., Lange, I., Fleig, A., Penner, R., Nishi, M., Takeshima, H., Mori, Y., TRPM2-mediated Ca2 + influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. Nat. Med. 14 (2008), 738–747.
-
(2008)
Nat. Med.
, vol.14
, pp. 738-747
-
-
Yamamoto, S.1
Shimizu, S.2
Kiyonaka, S.3
Takahashi, N.4
Wajima, T.5
Hara, Y.6
Negoro, T.7
Hiroi, T.8
Kiuchi, Y.9
Okada, T.10
Kaneko, S.11
Lange, I.12
Fleig, A.13
Penner, R.14
Nishi, M.15
Takeshima, H.16
Mori, Y.17
-
237
-
-
77955266662
-
Chemical physiology of oxidative stress-activated TRPM2 and TRPC5 channels
-
Yamamoto, S., Takahashi, N., Mori, Y., Chemical physiology of oxidative stress-activated TRPM2 and TRPC5 channels. Prog. Biophys. Mol. Biol. 103 (2010), 18–27.
-
(2010)
Prog. Biophys. Mol. Biol.
, vol.103
, pp. 18-27
-
-
Yamamoto, S.1
Takahashi, N.2
Mori, Y.3
-
238
-
-
83855165656
-
The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation
-
Di, A., Gao, X.P., Qian, F., Kawamura, T., Han, J., Hecquet, C., Ye, R.D., Vogel, S.M., Malik, A.B., The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation. Nat. Immunol. 13 (2011), 29–34.
-
(2011)
Nat. Immunol.
, vol.13
, pp. 29-34
-
-
Di, A.1
Gao, X.P.2
Qian, F.3
Kawamura, T.4
Han, J.5
Hecquet, C.6
Ye, R.D.7
Vogel, S.M.8
Malik, A.B.9
-
239
-
-
79251471450
-
Functional expression of TRPV4 cation channels in human mast cell line (HMC-1)
-
Kim, K.S., Shin, D.H., Nam, J.H., Park, K.S., Zhang, Y.H., Kim, W.K., Kim, S.J., Functional expression of TRPV4 cation channels in human mast cell line (HMC-1). Kor. J. Physiol. Pharmacol. 14 (2010), 419–425.
-
(2010)
Kor. J. Physiol. Pharmacol.
, vol.14
, pp. 419-425
-
-
Kim, K.S.1
Shin, D.H.2
Nam, J.H.3
Park, K.S.4
Zhang, Y.H.5
Kim, W.K.6
Kim, S.J.7
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