Emerging mechanistic targets in lung injury induced by combustion-generated particles

Toxicological Sciences

Volumn 132, Issue 2, 2013, Pages 253-267

  Fariss, Marc W ^a   Gilmour, M Ian ^b   Reilly, Christopher A ^c   Liedtke, Wolfgang ^d   Ghio, Andrew J ^b  

^a Altria Client Services Inc   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c UNIVERSITY OF UTAH   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium; Cigarette smoke; Humic like substances; Transient receptor potential channels; Vehicle emissions

Indexed keywords

CARBOXYHEMOGLOBIN; CIGARETTE SMOKE CONDENSATE; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MITOGEN ACTIVATED PROTEIN KINASE; NANOPARTICLE; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; RAF PROTEIN; RANTES; RAS PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 4;

AIR POLLUTION; ASTHMA; BINDING SITE; CALCIUM TRANSPORT; CELL ENGINEERING; CHRONIC OBSTRUCTIVE LUNG DISEASE; COMBUSTION; CYTOTOXICITY; ENZYME ACTIVATION; EPIGENETICS; EPITHELIUM CELL; EXHAUST GAS; EXPOSURE; FLY ASH; HUMAN; HUMIC SUBSTANCE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; LOSS OF FUNCTION MUTATION; LUNG INJURY; LUNG TOXICITY; MALIGNANT TRANSFORMATION; NONHUMAN; OXIDATIVE STRESS; PARTICULATE MATTER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVIEW; SMOKING CESSATION;

AIR POLLUTANTS; CALCIUM; CELLS, CULTURED; HUMANS; IRON; LUNG; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; PARTICLE SIZE; SMOKE; TOBACCO; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 84875237220     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft001     Document Type: Review

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