Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 182, Issue 6, 2010, Pages 774-783

  Riteau, Nicolas ^a   Gasse, Pamela ^a   Fauconnier, Louis ^a   Gombault, Aurélie ^a   Couegnat, Marion ^a   Fick, Lizette ^b   Kanellopoulos, Jean ^c   Quesniaux, Valérie F J ^a   Marchand Adam, Sylvain ^d   Crestani, Bruno ^e,f   Ryffel, Bernhard ^a   Couillin, Isabelle ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c CNRS   (France)

^d UNIVERSITÉ DE TOURS   (France)

^e INSERM   (France)

^f BICHAT HOSPITAL   (France)

Author keywords

ATP; Inflammation; Lung fibrosis; P2X7 receptor; Pannexin 1

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; APYRASE; BLEOMYCIN; COLLAGEN; GELATINASE B; INTERLEUKIN 1BETA; MEMBRANE PROTEIN; PANNEXIN 1; PURINERGIC P2X7 RECEPTOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG; PURINERGIC P2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRESS; CONTROLLED STUDY; DNA STRAND BREAKAGE; FIBROSING ALVEOLITIS; HUMAN; IN VITRO STUDY; INFLAMMATORY CELL; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; LUNG LAVAGE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CASE CONTROL STUDY; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DISEASE MODEL; LUNG INJURY; METABOLISM; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; BLEOMYCIN; BRONCHOALVEOLAR LAVAGE FLUID; CASE-CONTROL STUDIES; DISEASE MODELS, ANIMAL; HUMANS; LUNG INJURY; MICE; MICE, INBRED C57BL; PNEUMONIA; PULMONARY FIBROSIS; RECEPTORS, PURINERGIC P2; SIGNAL TRANSDUCTION;

EID: 77957101431     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201003-0359OC     Document Type: Article

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